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Term:keratan sulfate biosynthetic process
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Accession:GO:0018146 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.
Synonyms:exact_synonym: keratan sulfate anabolism;   keratan sulfate biosynthesis;   keratan sulfate formation;   keratan sulfate synthesis;   keratan sulphate biosynthesis;   keratan sulphate biosynthetic process
 xref: RESID:AA0247

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keratan sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst5 carbohydrate sulfotransferase 5 involved_in ISO
RGD PMID:11278593, PMID:21873635, PMID:21873635 MGI:1934540, RGD:13792537, RGD:13792537 NCBI chr19:44,115,065...44,136,092
Ensembl chr19:44,115,120...44,135,387
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  biological_process 20082
    metabolic process 12142
      cellular metabolic process 11078
        sulfur compound metabolic process 334
          sulfur compound biosynthetic process 111
            keratan sulfate biosynthetic process 1
Path 2
Term Annotations click to browse term
  biological_process 20082
    metabolic process 12142
      organic substance metabolic process 11647
        macromolecule metabolic process 10055
          aminoglycan metabolic process 122
            glycosaminoglycan metabolic process 103
              mucopolysaccharide metabolic process 80
                keratan sulfate metabolic process 3
                  keratan sulfate biosynthetic process 1
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