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ONTOLOGY REPORT - ANNOTATIONS


Term:keratan sulfate biosynthetic process
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Accession:GO:0018146 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.
Synonyms:exact_synonym: keratan sulfate anabolism;   keratan sulfate biosynthesis;   keratan sulfate formation;   keratan sulfate synthesis;   keratan sulphate biosynthesis;   keratan sulphate biosynthetic process
 xref: RESID:AA0247



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keratan sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:118,644,899...118,650,463 JBrowse link
G B4GALT4 beta-1,4-galactosyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:116,329,595...116,358,779
Ensembl chr 3:123,241,676...123,270,806
JBrowse link
G CHST1 carbohydrate sulfotransferase 1 involved_in ISO (PMID:17690104) UniProt PMID:17690104 NCBI chr11:45,604,605...45,621,332 JBrowse link
G CHST4 carbohydrate sulfotransferase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:53,472,432...53,485,605
Ensembl chr16:71,373,703...71,374,863
JBrowse link
G CHST5 carbohydrate sulfotransferase 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:56,097,770...56,105,546
Ensembl chr16:75,446,349...75,447,584
JBrowse link
G CHST6 carbohydrate sulfotransferase 6 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr16:56,041,518...56,062,463
Ensembl chr16:75,394,187...75,395,374
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 16313
    metabolic process 10179
      cellular metabolic process 8945
        sulfur compound metabolic process 305
          sulfur compound biosynthetic process 135
            keratan sulfate biosynthetic process 6
Path 2
Term Annotations click to browse term
  biological_process 16313
    metabolic process 10179
      organic substance metabolic process 9739
        macromolecule metabolic process 8210
          aminoglycan metabolic process 116
            glycosaminoglycan metabolic process 103
              mucopolysaccharide metabolic process 83
                keratan sulfate metabolic process 7
                  keratan sulfate biosynthetic process 6
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