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ONTOLOGY REPORT - ANNOTATIONS


Term:protein hydroxylation
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Accession:GO:0018126 term browser browse the term
Definition:The addition of a hydroxy group to a protein amino acid.
Synonyms:exact_synonym: protein amino acid hydroxylation



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protein hydroxylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egln3 egl-9 family hypoxia-inducible factor 3 involved_in ISO (PMID:19584355) RGD PMID:19584355 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Jmjd4 jumonji domain containing 4 involved_in ISO
IBA
(PMID:24486019)
PMID:21873635
RGD PMID:24486019 PMID:21873635 RGD:13792537 NCBI chr10:44,234,465...44,242,754
Ensembl chr10:44,234,549...44,240,065
JBrowse link
G Jmjd7 jumonji domain containing 7 involved_in ISO (PMID:29915238) RGD PMID:29915238 NCBI chr 3:106,998,454...107,004,538
Ensembl chr 3:106,998,477...107,004,538
JBrowse link
G Ogfod1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 involved_in ISO (PMID:24550447), (PMID:24550462) RGD PMID:24550447 PMID:24550462 NCBI chr19:10,948,778...10,974,566
Ensembl chr19:10,946,018...10,975,119
JBrowse link
G P3h1 prolyl 3-hydroxylase 1 involved_in ISO (PMID:17277775) RGD PMID:17277775 NCBI chr 5:132,841,868...132,856,664
Ensembl chr 5:132,841,928...132,856,659
JBrowse link
G Pah phenylalanine hydroxylase IDA RGD PMID:16953590 RGD:1601531 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
peptidyl-aspartic acid hydroxylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asph aspartate-beta-hydroxylase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2177999|PMID:11773073)
RGD PMID:11773073 PMID:21873635 MGI:2177999, RGD:13792537 NCBI chr 5:22,603,879...22,814,107
Ensembl chr 5:22,603,486...22,813,876
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor involved_in ISO
IBA
(PMID:21177872)
PMID:21873635
RGD PMID:21177872 PMID:21873635 RGD:13792537 NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327
JBrowse link
peptidyl-histidine hydroxylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor involved_in ISO
IBA
(PMID:21251231)
PMID:21873635
RGD PMID:21251231 PMID:21873635 RGD:13792537 NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327
JBrowse link
peptidyl-lysine hydroxylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fkbp10 FKBP prolyl isomerase 10 acts_upstream_of_or_within ISO MGI:5432211 (MGI:5585367|PMID:24777781), (MGI:6114458|PMID:28206698) RGD PMID:24777781 PMID:28206698 MGI:5585367 MGI:6114458 NCBI chr10:85,345,434...85,357,998
Ensembl chr10:85,346,126...85,427,330
JBrowse link
G P3h3 prolyl 3-hydroxylase 3 involved_in ISO (MGI:5888787|PMID:28115524) RGD PMID:28115524 MGI:5888787 NCBI chr 4:157,646,238...157,662,035
Ensembl chr 4:157,646,243...157,695,509
JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 involved_in IBA
IEA
ISO
ISS
PMID:21873635
GO_REF:0000107
(MGI:5779580|PMID:27119146)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:27119146 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5779580, RGD:13792537 NCBI chr10:85,338,158...85,345,108
Ensembl chr10:85,338,161...85,345,093
JBrowse link
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 involved_in IDA
IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:10934207), (PMID:8621606), (PMID:9724729)
PMID:7578263
Ensembl
RGD
PMID:8621606 PMID:9724729 PMID:10934207 PMID:11714250 PMID:21873635 More... GO_REF:0000107, RGD:1599090, RGD:13792537, RGD:734487 NCBI chr 5:158,340,674...158,367,581
Ensembl chr 5:158,340,490...158,367,620
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 involved_in IEA
ISO
IBA
GO_REF:0000107
(PMID:10934207)
PMID:21873635
Ensembl
RGD
PMID:10934207 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
ISS
PMID:21873635
(MGI:5804716|PMID:27435297)
(MGI:6202004|PMID:16447251)
GO_REF:0000024
(PMID:10934207), (PMID:18298658), (PMID:9582318), (PMID:9724729)
RGD
UniProt
PMID:9582318 PMID:9724729 PMID:10934207 PMID:16447251 PMID:18298658 More... GO_REF:0000024 MGI:5804716 MGI:6202004, RGD:13792537 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960
JBrowse link
G Vipas39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog acts_upstream_of_or_within ISO MGI:3699244|MGI:5816979 (MGI:5804716|PMID:27435297)
(PMID:27435297)
RGD PMID:27435297 MGI:5804716 NCBI chr 6:106,888,284...106,913,139
Ensembl chr 6:106,888,284...106,913,117
JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated acts_upstream_of_or_within ISO MGI:3699244|MGI:5770088 (MGI:5804716|PMID:27435297)
(PMID:27435297)
RGD PMID:27435297 MGI:5804716 NCBI chr 1:134,223,967...134,247,232
Ensembl chr 1:134,223,949...134,246,970
JBrowse link
peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase involved_in ISS
ISO
GO_REF:0000024
(PMID:19574390)
(PMID:19574390), (PMID:22189873)
UniProt
RGD
PMID:19574390 PMID:22189873 GO_REF:0000024 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
JBrowse link
peptidyl-proline hydroxylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egln3 egl-9 family hypoxia-inducible factor 3 acts_upstream_of_or_within ISO (MGI:5574277|PMID:24030251) RGD PMID:24030251 MGI:5574277 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Gpr162 G protein-coupled receptor 162 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:157,662,200...157,668,341 JBrowse link
G Ogfod1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 involved_in IBA
ISO
PMID:21873635
(PMID:24550447)
RGD PMID:24550447 PMID:21873635 RGD:13792537 NCBI chr19:10,948,778...10,974,566
Ensembl chr19:10,946,018...10,975,119
JBrowse link
G P3h1 prolyl 3-hydroxylase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:132,841,868...132,856,664
Ensembl chr 5:132,841,928...132,856,659
JBrowse link
G P3h2 prolyl 3-hydroxylase 2 involved_in ISO
IEA
ISS
IDA
(PMID:18487197)
GO_REF:0000107
GO_REF:0000024
PMID:21757687
RGD
Ensembl
UniProt
PMID:18487197 PMID:21757687 GO_REF:0000024 GO_REF:0000107, RGD:8553392 NCBI chr11:74,634,267...74,775,422
Ensembl chr11:74,634,267...74,775,421
JBrowse link
G P3h3 prolyl 3-hydroxylase 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:157,646,238...157,662,035
Ensembl chr 4:157,646,243...157,695,509
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3706369 (MGI:3706231|PMID:17135260)
(MGI:72931|PMID:7753822)
GO_REF:0000108
RGD
GOC
PMID:7753822 PMID:17135260 GO_REF:0000108 MGI:3706231 MGI:72931 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 acts_upstream_of_or_within ISO (MGI:72931|PMID:7753822) RGD PMID:7753822 MGI:72931 NCBI chr10:38,243,047...38,271,989
Ensembl chr10:38,243,139...38,287,314
JBrowse link
G P4ha3 prolyl 4-hydroxylase subunit alpha 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:154,628,723...154,663,779
Ensembl chr 1:154,628,736...154,663,775
JBrowse link
peptidyl-proline hydroxylation to 3-hydroxy-L-proline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crtap cartilage associated protein involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3693334 (MGI:3692844|PMID:17055431)
RGD PMID:17055431 PMID:21873635 MGI:3692844, RGD:13792537 NCBI chr 8:114,047,929...114,067,648
Ensembl chr 8:114,047,933...114,067,631
JBrowse link
peptidyl-proline hydroxylation to 4-hydroxy-L-proline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egln1 egl-9 family hypoxia-inducible factor 1 involved_in IBA
ISO
PMID:21873635
(PMID:11598268)
RGD PMID:11598268 PMID:21873635 RGD:13792537 NCBI chr19:52,867,914...52,907,169
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 involved_in ISO
IDA
IBA
(PMID:11598268), (PMID:12039559)
PMID:15925519
PMID:21873635
RGD PMID:11598268 PMID:12039559 PMID:15925519 PMID:21873635 RGD:13602003, RGD:13792537 NCBI chr 1:82,451,554...82,459,809
Ensembl chr 1:82,451,555...82,459,751
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 involved_in IBA
ISO
PMID:21873635
(PMID:11598268)
RGD PMID:11598268 PMID:21873635 RGD:13792537 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha acts_upstream_of_or_within ISO MGI:1859815|MGI:1914725 (MGI:5461404|PMID:22981861) RGD PMID:22981861 MGI:5461404 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta acts_upstream_of_or_within ISO MGI:1354385|MGI:1859815 (MGI:5461404|PMID:22981861) RGD PMID:22981861 MGI:5461404 NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 acts_upstream_of_or_within
involved_in
TAS
ISO
IBA
(MGI:72931|PMID:7753822)
PMID:21873635
RGD PMID:7753822 PMID:11997102 PMID:21873635 MGI:72931, RGD:625562, RGD:13792537 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:72931|PMID:7753822)
RGD PMID:7753822 PMID:21873635 MGI:72931, RGD:13792537 NCBI chr10:38,243,047...38,271,989
Ensembl chr10:38,243,139...38,287,314
JBrowse link
G P4ha3 prolyl 4-hydroxylase subunit alpha 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:154,628,723...154,663,779
Ensembl chr 1:154,628,736...154,663,775
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta acts_upstream_of_or_within ISO (PMID:7753822) RGD PMID:7753822 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G P4htm prolyl 4-hydroxylase, transmembrane involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:109,274,629...109,292,802
Ensembl chr 8:109,274,626...109,292,473
JBrowse link
G Prdx4 peroxiredoxin 4 acts_upstream_of_or_within ISO MGI:1354385|MGI:1914725 (MGI:5461404|PMID:22981861) RGD PMID:22981861 MGI:5461404 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19876
    metabolic process 12192
      primary metabolic process 10955
        protein metabolic process 6101
          protein modification process 3730
            protein hydroxylation 30
              peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine 0
              peptidyl-aspartic acid hydroxylation + 2
              peptidyl-histidine hydroxylation 1
              peptidyl-lysine hydroxylation + 9
              peptidyl-proline hydroxylation + 17
              peptidyl-tyrosine hydroxylation + 0
Path 2
Term Annotations click to browse term
  biological_process 19876
    metabolic process 12192
      organic substance metabolic process 11723
        macromolecule metabolic process 10080
          protein metabolic process 6101
            protein modification process 3730
              protein hydroxylation 30
                peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine 0
                peptidyl-aspartic acid hydroxylation + 2
                peptidyl-histidine hydroxylation 1
                peptidyl-lysine hydroxylation + 9
                peptidyl-proline hydroxylation + 17
                peptidyl-tyrosine hydroxylation + 0
paths to the root