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ONTOLOGY REPORT - ANNOTATIONS


Term:peptidyl-diphthamide biosynthetic process from peptidyl-histidine
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Accession:GO:0017183 term browser browse the term
Definition:The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
Synonyms:exact_synonym: peptidyl-diphthamide anabolism from peptidyl-histidine;   peptidyl-diphthamide formation from peptidyl-histidine;   peptidyl-diphthamide synthesis from peptidyl-histidine
 xref: RESID:AA0040



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peptidyl-diphthamide biosynthetic process from peptidyl-histidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dph1 diphthamide biosynthesis 1 involved_in ISO
IEA
IBA
(MGI:5603957|PMID:24895408)
GO_REF:0000041
PMID:21873635
RGD
UniProt
PMID:24895408 PMID:21873635 GO_REF:0000041 MGI:5603957, RGD:13792537 NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,026,048...60,039,850
JBrowse link
G Dph2 diphthamide biosynthesis 2 involved_in IEA
IBA
ISS
ISO
GO_REF:0000041
PMID:21873635
GO_REF:0000024
(PMID:32576952)
UniProt
RGD
PMID:32576952 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr 5:131,428,434...131,431,394
Ensembl chr 5:131,428,268...131,431,395
JBrowse link
G Dph3 diphthamide biosynthesis 3 involved_in ISO (MGI:3625663|PMID:16648478) RGD PMID:16648478 MGI:3625663 NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265
JBrowse link
G Dph5 diphthamide biosynthesis 5 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:203,804,620...203,858,196
Ensembl chr 2:203,804,936...203,840,433
JBrowse link
G Dph6 diphthamine biosynthesis 6 involved_in IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:101,307,229...101,437,463
Ensembl chr 3:101,307,231...101,534,603
JBrowse link
G Dph7 diphthamide biosynthesis 7 involved_in ISO
ISS
IBA
(PMID:19965467)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:19965467 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:7,770,385...7,778,994
Ensembl chr 3:7,770,379...7,778,982
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    metabolic process 11591
      biosynthetic process 5893
        cellular biosynthetic process 5729
          peptidyl-diphthamide biosynthetic process from peptidyl-histidine 6
Path 2
Term Annotations click to browse term
  biological_process 18877
    metabolic process 11591
      nitrogen compound metabolic process 9873
        cellular nitrogen compound metabolic process 6553
          cellular amide metabolic process 1512
            peptide metabolic process 1248
              peptide biosynthetic process 1074
                translation 1050
                  cytoplasmic translation 211
                    cytoplasmic translational elongation 13
                      regulation of cytoplasmic translational elongation 9
                        peptidyl-diphthamide biosynthetic process from peptidyl-histidine 6
paths to the root