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ONTOLOGY REPORT - ANNOTATIONS


Term:peptidyl-diphthamide biosynthetic process from peptidyl-histidine
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Accession:GO:0017183 term browser browse the term
Definition:The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
Synonyms:exact_synonym: peptidyl-diphthamide anabolism from peptidyl-histidine;   peptidyl-diphthamide formation from peptidyl-histidine;   peptidyl-diphthamide synthesis from peptidyl-histidine
 xref: RESID:AA0040


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peptidyl-diphthamide biosynthetic process from peptidyl-histidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dph1 diphthamide biosynthesis 1 involved_in IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr10:62,019,379...62,032,384
Ensembl chr10:62,019,379...62,032,407
JBrowse link
G Dph2 diphthamide biosynthesis 2 involved_in IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 5:136,723,398...136,726,358
Ensembl chr 5:136,723,406...136,726,358
JBrowse link
G Dph3 diphthamide biosynthesis 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:8,202,048...8,207,492
Ensembl chr16:8,202,048...8,207,464
JBrowse link
G Dph5 diphthamide biosynthesis 5 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:218,834,034...218,866,763
Ensembl chr 2:218,834,034...218,866,761
JBrowse link
G Dph6 diphthamine biosynthesis 6 involved_in IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:106,007,721...106,136,662
Ensembl chr 3:106,009,356...106,136,615
JBrowse link
G Dph7 diphthamide biosynthesis 7 involved_in ISO
ISS
(PMID:19965467)
GO_REF:0000024
RGD
UniProt
PMID:19965467 GO_REF:0000024 NCBI chr 3:2,170,193...2,179,101
Ensembl chr 3:2,170,533...2,179,010
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    cellular process 18451
      cellular metabolic process 10814
        cellular biosynthetic process 5985
          peptidyl-diphthamide biosynthetic process from peptidyl-histidine 6
Path 2
Term Annotations click to browse term
  biological_process 19599
    metabolic process 11860
      nitrogen compound metabolic process 10074
        cellular nitrogen compound metabolic process 6615
          cellular amide metabolic process 1540
            peptide metabolic process 1290
              peptide biosynthetic process 1123
                translation 1103
                  cytoplasmic translation 242
                    cytoplasmic translational elongation 13
                      regulation of cytoplasmic translational elongation 8
                        peptidyl-diphthamide biosynthetic process from peptidyl-histidine 6
paths to the root