Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:calcium-ion regulated exocytosis
go back to main search page
Accession:GO:0017156 term browser browse the term
Definition:The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.
Comment:Note that the calcium regulated exocytosis pathway can be leaky: some level of exocytosis via this pathway occurs spontaneously. This phenomenon underlies spontaneous neurotransmitter release from presynapses. This phenomenon is distinct from the unregulated, calcium independent exocytosis pathway.
Synonyms:exact_synonym: calcium ion-dependent exocytosis


show annotations for term's descendants           Sort by:
calcium-ion regulated exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap17 Rho GTPase activating protein 17 acts_upstream_of_or_within IDA PMID:10967100 MGI PMID:10967100 RGD:633422 NCBI chr 1:177,807,579...177,897,027
Ensembl chr 1:177,807,583...177,896,854 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:2181384 (PMID:12065603) RGD PMID:12065603 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C acts_upstream_of_or_within ISO MGI:2176227|MGI:2674119 (PMID:12881419) RGD PMID:12881419 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cltrn collectrin, amino acid transport regulator acts_upstream_of_positive_effect
involved_in		 ISO
IEA		 (PMID:16330323)
GO_REF:0000107		 RGD
Ensembl		 PMID:16330323 GO_REF:0000107 NCBI chr  X:30,361,967...30,395,264
Ensembl chr  X:30,361,967...30,395,349 		JBrowse link
G Notch1 notch receptor 1 acts_upstream_of ISO MGI:2684314 (PMID:19251639) RGD PMID:19251639 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:11978799)
GO_REF:0000107
(MGI:5306323|PMID:11978799)		 UniProt
RGD
Ensembl		 PMID:11978799 GO_REF:0000024 GO_REF:0000107 MGI:5306323 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in ISO
IBA		 (MGI:4830800|PMID:20338242)
(PMID:20338242)
GO_REF:0000033		 RGD
GO_Central		 PMID:20338242 GO_REF:0000033 MGI:4830800 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family acts_upstream_of ISO MGI:97852 (PMID:23616533) RGD PMID:23616533 NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:11056535)		 Ensembl
RGD		 PMID:11056535 GO_REF:0000107 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:11056535)		 ParkinsonsUK-UCL
RGD		 PMID:11056535 GO_REF:0000024 NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491 		JBrowse link
G Rims3 regulating synaptic membrane exocytosis 3 IDA RGD PMID:10748113 RGD:633421 NCBI chr 5:134,429,092...134,468,935
Ensembl chr 5:134,435,829...134,640,489 		JBrowse link
G Sdf4 stromal cell derived factor 4 involved_in IMP
IBA		 PMID:17442889
GO_REF:0000033		 GO_Central PMID:17442889 GO_REF:0000033, RGD:2312426 NCBI chr 5:166,586,581...166,606,661
Ensembl chr 5:166,586,390...166,604,521 		JBrowse link
G Stx1a syntaxin 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:10468580)		 Ensembl
RGD		 PMID:10468580 GO_REF:0000107 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930 		JBrowse link
G Syn2 synapsin II involved_in IEA
ISO		 GO_REF:0000107
(PMID:20338242)
(MGI:4830800|PMID:20338242)		 Ensembl
RGD		 PMID:20338242 GO_REF:0000107 MGI:4830800 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192 		JBrowse link
G Syt1 synaptotagmin 1 TAS RGD PMID:2333096 RGD:729959 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803 		JBrowse link
G Syt10 synaptotagmin 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:120,857,698...120,920,863
Ensembl chr 7:120,862,972...120,920,863 		JBrowse link
G Syt12 synaptotagmin 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:201,729,307...201,760,192
Ensembl chr 1:201,730,371...201,759,609 		JBrowse link
G Syt13 synaptotagmin 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:78,877,114...78,917,527
Ensembl chr 3:78,877,114...78,917,392 		JBrowse link
G Syt15 synaptotagmin 15 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:9,532,478...9,543,288
Ensembl chr16:9,532,478...9,543,281 		JBrowse link
G Syt17 synaptotagmin 17 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:172,695,275...172,761,906
Ensembl chr 1:172,696,120...172,761,960 		JBrowse link
G Syt3 synaptotagmin 3 involved_in TAS
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:7791877 GO_REF:0000033, RGD:61762 NCBI chr 1:94,880,835...94,895,518
Ensembl chr 1:94,881,247...94,895,246 		JBrowse link
G Syt4 synaptotagmin 4 NAS RGD PMID:7892240 RGD:730180 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
G Syt5 synaptotagmin 5 NAS RGD PMID:12006594 RGD:730140 NCBI chr 1:69,277,351...69,285,071
Ensembl chr 1:69,277,351...69,285,067 		JBrowse link
G Syt6 synaptotagmin 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:191,093,009...191,152,283
Ensembl chr 2:191,093,007...191,149,956 		JBrowse link
G Syt7 synaptotagmin 7 involved_in IDA PMID:11395007 UniProt PMID:11395007 RGD:634203 NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026 		JBrowse link
G Syt7_v1 synaptotagmin 7, variant 1 TAS RGD PMID:12071850 RGD:619692
G Syt7_v2 synaptotagmin 7, variant 2 TAS RGD PMID:12071850 RGD:619692
G Syt7_v3 synaptotagmin 7, variant 3 TAS RGD PMID:12071850 RGD:619692
G Syt9 synaptotagmin 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:161,275,882...161,456,384
Ensembl chr 1:161,275,734...161,455,007 		JBrowse link
G Tspan18 tetraspanin 18 acts_upstream_of_or_within ISO MGI:5007398 (PMID:30573509) RGD PMID:30573509 NCBI chr 3:79,160,060...79,299,907
Ensembl chr 3:79,161,662...79,299,852 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 acts_upstream_of_or_within ISO MGI:2179745 (PMID:12145198), (PMID:15920476) RGD PMID:12145198 PMID:15920476 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Vamp3 vesicle-associated membrane protein 3 acts_upstream_of_or_within ISO MGI:2385941 (PMID:15920476) RGD PMID:15920476 NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in IDA PMID:14993220 UniProt PMID:14993220 RGD:8553828 NCBI chr12:16,728,486...16,764,261
Ensembl chr12:16,728,524...16,764,097 		JBrowse link
acrosomal vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eqtn equatorin involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000002
(PMID:19285662)
GO_REF:0000033		 InterPro
RGD
GO_Central		 PMID:19285662 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:109,734,495...109,762,048
Ensembl chr 5:109,728,999...109,761,840 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in ISO
IEA		 (PMID:22248876)
GO_REF:0000107		 RGD
Ensembl		 PMID:22248876 GO_REF:0000107 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in ISO (PMID:22248876) RGD PMID:22248876 NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631 		JBrowse link
G Syt6 synaptotagmin 6 involved_in ISO
IEA		 (PMID:11437455)
GO_REF:0000107		 RGD
Ensembl		 PMID:11437455 GO_REF:0000107 NCBI chr 2:191,093,009...191,152,283
Ensembl chr 2:191,093,007...191,149,956 		JBrowse link
G Unc13b unc-13 homolog B involved_in ISO (PMID:22248876) RGD PMID:22248876 NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926 		JBrowse link
G Zp4 zona pellucida glycoprotein 4 involved_in ISO
IEA		 (PMID:19004505)
GO_REF:0000107		 RGD
Ensembl		 PMID:19004505 GO_REF:0000107 NCBI chr17:59,005,649...59,012,202
Ensembl chr17:59,005,649...59,012,202 		JBrowse link
calcium ion regulated lysosome exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ADP-ribosylation factor like GTPase 8B involved_in ISS
ISO		 GO_REF:0000024
(PMID:29592961)		 UniProt
RGD		 PMID:29592961 GO_REF:0000024 NCBI chr 4:141,748,634...141,792,605
Ensembl chr 4:141,748,587...141,792,596 		JBrowse link
G Syt11 synaptotagmin 11 involved_in ISO
IEA		 (MGI:5788615|PMID:26450452)
(PMID:26450452)
GO_REF:0000107		 RGD
Ensembl		 PMID:26450452 GO_REF:0000107 MGI:5788615 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964 		JBrowse link
G Syt7 synaptotagmin 7 involved_in IDA
ISO		 PMID:10725327
(MGI:3690533|PMID:16982801), (MGI:3798323|PMID:18539119)
PMID:11511344		 RGD PMID:16982801 PMID:18539119 PMID:10725327 PMID:11511344 MGI:3690533 MGI:3798323, RGD:2311145, RGD:11041027 NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026 		JBrowse link
calcium ion-regulated exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:1856209 (PMID:10670432) RGD PMID:10670432 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Doc2b double C2 domain beta involved_in IDA
ISO
IEA		 PMID:20150444
(MGI:4439222|PMID:20150444)
GO_REF:0000107		 RGD
Ensembl		 PMID:20150444 PMID:20150444 GO_REF:0000107 MGI:4439222, RGD:8554647 NCBI chr10:60,628,029...60,653,267
Ensembl chr10:60,628,029...60,653,267 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2152972 (PMID:17124501)		 GO_Central
RGD		 PMID:17124501 GO_REF:0000033 NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA		 GO_REF:0000024
MGI:2152971 (PMID:17124501)
GO_REF:0000033		 ParkinsonsUK-UCL
RGD
GO_Central		 PMID:17124501 GO_REF:0000024 GO_REF:0000033 NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491 		JBrowse link
G Rims3 regulating synaptic membrane exocytosis 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:134,429,092...134,468,935
Ensembl chr 5:134,435,829...134,640,489 		JBrowse link
G Rims4 regulating synaptic membrane exocytosis 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:152,520,982...152,585,070
Ensembl chr 3:152,524,095...152,584,780 		JBrowse link
G Snap25 synaptosome associated protein 25 IDA RGD PMID:14980208 RGD:1581082 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
G Stx1b syntaxin 1B involved_in IEA
ISO		 GO_REF:0000107
(PMID:18703708)
(MGI:3803800|PMID:18703708)		 Ensembl
RGD		 PMID:18703708 GO_REF:0000107 MGI:3803800 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280 		JBrowse link
G Syt1 synaptotagmin 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1857252 (PMID:21521611)		 GO_Central
RGD		 PMID:21521611 GO_REF:0000033 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803 		JBrowse link
G Syt11 synaptotagmin 11 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964 		JBrowse link
G Syt2 synaptotagmin 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859 		JBrowse link
G Syt4 synaptotagmin 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
G Syt5 synaptotagmin 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:69,277,351...69,285,071
Ensembl chr 1:69,277,351...69,285,067 		JBrowse link
G Syt7 synaptotagmin 7 involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:26738595)
GO_REF:0000033
(MGI:5707519|PMID:26738595)		 UniProt
RGD
GO_Central		 PMID:26738595 GO_REF:0000024 GO_REF:0000033 MGI:5707519 NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026 		JBrowse link
G Syt8 synaptotagmin 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:197,588,126...197,593,598
Ensembl chr 1:197,590,149...197,593,504 		JBrowse link
cortical granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh9 myosin, heavy chain 9 involved_in ISO
IEA
ISS		 (MGI:6323780|PMID:31118423)
(PMID:31118423)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:31118423 GO_REF:0000024 GO_REF:0000107 MGI:6323780 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Nlrp5 NLR family, pyrin domain containing 5 involved_in ISO (MGI:6323780|PMID:31118423)
(PMID:31118423)		 RGD PMID:31118423 MGI:6323780 NCBI chr 1:67,778,037...67,810,941
Ensembl chr 1:67,777,948...68,023,736 		JBrowse link
dense core granule docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A NOT|involved_in ISO UniProtKB:Q9Z1N9 (MGI:5819330|PMID:26575293)
UniProtKB:Q9Z1N9 (PMID:26575293)		 RGD PMID:26575293 MGI:5819330 NCBI chr16:18,333,910...18,381,813
Ensembl chr16:18,336,229...18,381,872 		JBrowse link
G Unc13b unc-13 homolog B NOT|involved_in ISO UniProtKB:Q4KUS2 (MGI:5819330|PMID:26575293)
UniProtKB:Q4KUS2 (PMID:26575293)		 RGD PMID:26575293 MGI:5819330 NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926 		JBrowse link
dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadps calcium dependent secretion activator involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:12,289,803...12,742,786
Ensembl chr15:12,290,262...12,742,779 		JBrowse link
G Cadps2 calcium dependent secretion activator 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829 		JBrowse link
dense core granule priming term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A involved_in IGI
IBA		 PMID:26575293
GO_REF:0000033		 GO_Central PMID:26575293 GO_REF:0000033, RGD:12050107 NCBI chr16:18,333,910...18,381,813
Ensembl chr16:18,336,229...18,381,872 		JBrowse link
G Unc13b unc-13 homolog B involved_in IGI
IBA		 PMID:26575293
GO_REF:0000033		 GO_Central PMID:26575293 GO_REF:0000033, RGD:12050107 NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926 		JBrowse link
G Unc13c unc-13 homolog C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:74,247,026...74,697,629
Ensembl chr 8:74,247,899...74,673,223 		JBrowse link
G Unc13d unc-13 homolog D involved_in IGI PMID:26575293 SynGO-UCL PMID:26575293 RGD:12050107 NCBI chr10:101,296,755...101,311,513
Ensembl chr10:101,296,776...101,311,687 		JBrowse link
fast, calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt1 synaptotagmin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12526776), (PMID:7954835), (PMID:9194562)
(MGI:3040539|PMID:12526776), (MGI:3653150|PMID:9194562), (MGI:69538|PMID:7954835)		 ParkinsonsUK-UCL
RGD		 PMID:7954835 PMID:9194562 PMID:12526776 GO_REF:0000024 MGI:3040539 MGI:3653150 MGI:69538 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803 		JBrowse link
negative regulation of calcium ion-dependent exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A involved_in IMP PMID:19965390 BHF-UCL PMID:19965390 RGD:2316628 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Cbarp CACN subunit beta associated regulatory protein involved_in ISO (MGI:5607190|PMID:24751537)
(PMID:24751537)		 RGD PMID:24751537 MGI:5607190 NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204 		JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:11533141 RGD:13508598 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:2684314 (PMID:19251639) RGD PMID:19251639 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:2357966) RGD PMID:2357966 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in IC PMID:19965390 BHF-UCL PMID:19965390 RGD:2316628 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family acts_upstream_of_or_within ISO MGI:97852 (PMID:23616533) RGD PMID:23616533 NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370 		JBrowse link
G Rest RE1-silencing transcription factor involved_in IMP PMID:21536750 UniProt PMID:21536750 RGD:8554180 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
G Stxbp3 syntaxin binding protein 3 involved_in ISO (PMID:12649283) RGD PMID:12649283 NCBI chr 2:196,442,738...196,485,733
Ensembl chr 2:196,442,634...196,485,671 		JBrowse link
G Syt4 synaptotagmin 4 IDA RGD PMID:21551071 RGD:7205660 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
G Trim9 tripartite motif-containing 9 IMP RGD PMID:11524423 RGD:631246 NCBI chr 6:88,756,824...88,856,588
Ensembl chr 6:88,757,303...88,856,542 		JBrowse link
negative regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 involved_in IMP PMID:20303854 ParkinsonsUK-UCL PMID:20303854 RGD:11541109 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
neuronal dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A involved_in ISS
ISO		 GO_REF:0000024
(MGI:5476894|PMID:23229896)		 UniProt
RGD		 PMID:23229896 GO_REF:0000024 MGI:5476894 NCBI chr16:18,333,910...18,381,813
Ensembl chr16:18,336,229...18,381,872 		JBrowse link
G Unc13b unc-13 homolog B involved_in ISS
ISO		 GO_REF:0000024
(MGI:5476894|PMID:23229896)		 UniProt
RGD		 PMID:23229896 GO_REF:0000024 MGI:5476894 NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926 		JBrowse link
positive regulation of acrosomal vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyal3 hyaluronidase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4834982|PMID:20586096)
(PMID:20586096)		 UniProt
RGD		 PMID:20586096 GO_REF:0000024 MGI:4834982 NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647 		JBrowse link
G Zp3 zona pellucida glycoprotein 3 involved_in ISO
ISS		 (PMID:19004505), (PMID:19246320)
GO_REF:0000024		 RGD
UniProt		 PMID:19004505 PMID:19246320 GO_REF:0000024 NCBI chr12:20,690,547...20,697,513
Ensembl chr12:20,690,547...20,697,513 		JBrowse link
positive regulation of calcium ion-dependent exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP-ribosylation factor 1 IDA RGD PMID:10657240 RGD:9684853 NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:17172292 GO_REF:0000033, RGD:2316206 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688 		JBrowse link
G Cadps calcium dependent secretion activator IMP RGD PMID:9289490 RGD:1299539 NCBI chr15:12,289,803...12,742,786
Ensembl chr15:12,290,262...12,742,779 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15123626)		 Ensembl
RGD		 PMID:15123626 GO_REF:0000107 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cdk5r2 cyclin-dependent kinase 5 regulatory subunit 2 acts_upstream_of_or_within ISO (PMID:15123626) RGD PMID:15123626 NCBI chr 9:76,416,251...76,417,719
Ensembl chr 9:76,416,062...76,418,344 		JBrowse link
G Doc2b double C2 domain beta involved_in IDA PMID:18596155 UniProt PMID:18596155 RGD:8554556 NCBI chr10:60,628,029...60,653,267
Ensembl chr10:60,628,029...60,653,267 		JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 involved_in IDA PMID:18167541
PMID:17301173
PMID:20484665		 UniProt PMID:18167541 PMID:17301173 PMID:20484665 RGD:10047360, RGD:10047384, RGD:10047179 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194 		JBrowse link
G Scamp5 secretory carrier membrane protein 5 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19234194)		 UniProt
Ensembl
RGD		 PMID:19234194 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:57,845,831...57,884,516
Ensembl chr 8:57,846,659...57,872,027 		JBrowse link
G Stx1a syntaxin 1A involved_in IDA PMID:17301173
PMID:20484665
PMID:18167541		 UniProt PMID:17301173 PMID:20484665 PMID:18167541 RGD:10047384, RGD:10047179, RGD:10047360 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930 		JBrowse link
G Stxbp1 syntaxin binding protein 1 acts_upstream_of_or_within ISO (PMID:15123626) RGD PMID:15123626 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
G Syt1 synaptotagmin 1 IDA RGD PMID:21551071 RGD:7205660 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803 		JBrowse link
G Syt10 synaptotagmin 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21496647)
(MGI:5751674|PMID:21496647)		 UniProt
RGD		 PMID:21496647 GO_REF:0000024 MGI:5751674 NCBI chr 7:120,857,698...120,920,863
Ensembl chr 7:120,862,972...120,920,863 		JBrowse link
G Syt7 synaptotagmin 7 IDA RGD PMID:21551071 RGD:7205660 NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026 		JBrowse link
G Syt9 synaptotagmin 9 IDA RGD PMID:21551071 RGD:7205660 NCBI chr 1:161,275,882...161,456,384
Ensembl chr 1:161,275,734...161,455,007 		JBrowse link
positive regulation of calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt1 synaptotagmin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11242035)
(MGI:2179533|PMID:11242035)		 UniProt
RGD		 PMID:11242035 GO_REF:0000024 MGI:2179533 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803 		JBrowse link
positive regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 involved_in ISO (MGI:3795609|PMID:18468511)
(PMID:18468511)		 RGD PMID:18468511 MGI:3795609 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt6 synaptotagmin 6 involved_in IDA
IMP		 PMID:26216953 SynGO PMID:26216953 PMID:26216953 RGD:13702162, RGD:13702162 NCBI chr 2:191,093,009...191,152,283
Ensembl chr 2:191,093,007...191,149,956 		JBrowse link
presynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadps calcium dependent secretion activator involved_in ISO
IEA		 UniProtKB:Q8BYR5 (MGI:5634021|PMID:25719439), (PMID:25719439)
GO_REF:0000107		 RGD
Ensembl		 PMID:25719439 GO_REF:0000107 MGI:5634021 NCBI chr15:12,289,803...12,742,786
Ensembl chr15:12,290,262...12,742,779 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in ISO (PMID:31679900) RGD PMID:31679900 NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631 		JBrowse link
G Snap25 synaptosome associated protein 25 involved_in IEA
ISO		 GO_REF:0000107
(PMID:28404788)		 Ensembl
RGD		 PMID:28404788 GO_REF:0000107 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
G Stxbp1 syntaxin binding protein 1 involved_in ISO (MGI:3621672|PMID:11545717) RGD PMID:11545717 MGI:3621672 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
G Syt10 synaptotagmin 10 involved_in ISO (PMID:28683263) RGD PMID:28683263 NCBI chr 7:120,857,698...120,920,863
Ensembl chr 7:120,862,972...120,920,863 		JBrowse link
G Unc13a unc-13 homolog A involved_in ISO
IBA		 UniProtKB:Q9Z1N9 (MGI:5819330|PMID:26575293)
GO_REF:0000033		 RGD
GO_Central		 PMID:26575293 GO_REF:0000033 MGI:5819330 NCBI chr16:18,333,910...18,381,813
Ensembl chr16:18,336,229...18,381,872 		JBrowse link
G Unc13b unc-13 homolog B involved_in ISO
IBA		 (MGI:5819330|PMID:26575293)
GO_REF:0000033		 RGD
GO_Central		 PMID:26575293 GO_REF:0000033 MGI:5819330 NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926 		JBrowse link
G Unc13c unc-13 homolog C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:74,247,026...74,697,629
Ensembl chr 8:74,247,899...74,673,223 		JBrowse link
regulation of acrosomal vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stxbp1 syntaxin binding protein 1 involved_in ISO (PMID:23091057) RGD PMID:23091057 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
regulation of calcium ion-dependent exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO (PMID:8632762) RGD PMID:8632762 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Doc2a double C2 domain alpha involved_in ISO
IBA		 (PMID:18354201)
GO_REF:0000033
(MGI:3778349|PMID:18354201)		 RGD
GO_Central		 PMID:18354201 GO_REF:0000033 MGI:3778349 NCBI chr 1:181,457,415...181,462,528
Ensembl chr 1:181,458,390...181,462,030 		JBrowse link
G Doc2b double C2 domain beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:60,628,029...60,653,267
Ensembl chr10:60,628,029...60,653,267 		JBrowse link
G Doc2g double C2-like domains, gamma involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:201,295,377...201,299,867
Ensembl chr 1:201,296,342...201,299,865 		JBrowse link
G Rph3a rabphilin 3A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:35,542,389...35,618,901
Ensembl chr12:35,542,728...35,617,592 		JBrowse link
G Rph3al rabphilin 3A-like (without C2 domains) involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3051976 (PMID:15159548)		 GO_Central
RGD		 PMID:15159548 GO_REF:0000033 NCBI chr10:60,689,943...60,833,354
Ensembl chr10:60,690,031...60,801,883 		JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 involved_in TAS PMID:9704016 UniProt PMID:9704016 RGD:70020 NCBI chr 1:202,002,970...202,045,343
Ensembl chr 1:202,002,970...202,044,283 		JBrowse link
G Sycn syncollin TAS RGD PMID:9244306 RGD:634177 NCBI chr 1:83,823,836...83,833,542
Ensembl chr 1:83,832,102...83,833,538 		JBrowse link
G Syt1 synaptotagmin 1 involved_in IMP
ISO		 (PMID:11562488)
(MGI:3761204|PMID:11562488)
PMID:12860971		 RGD PMID:11562488 PMID:11751925 PMID:12860971 PMID:17686463 MGI:3761204, RGD:2311146, RGD:11079189, RGD:7205657 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803 		JBrowse link
G Syt10 synaptotagmin 10 involved_in ISO (MGI:5780544|PMID:12860971)
(PMID:12860971)		 RGD PMID:12860971 MGI:5780544 NCBI chr 7:120,857,698...120,920,863
Ensembl chr 7:120,862,972...120,920,863 		JBrowse link
G Syt3 synaptotagmin 3 involved_in IMP PMID:12860971 ParkinsonsUK-UCL PMID:12860971 RGD:11079189 NCBI chr 1:94,880,835...94,895,518
Ensembl chr 1:94,881,247...94,895,246 		JBrowse link
G Syt4 synaptotagmin 4 involved_in ISO (MGI:3836866|PMID:19136969), (MGI:4421257|PMID:20010821)
(PMID:19136969), (PMID:20010821)		 RGD PMID:19136969 PMID:20010821 MGI:3836866 MGI:4421257 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
G Syt5 synaptotagmin 5 involved_in ISO (MGI:5780544|PMID:12860971)
(PMID:12860971)		 RGD PMID:12860971 MGI:5780544 NCBI chr 1:69,277,351...69,285,071
Ensembl chr 1:69,277,351...69,285,067 		JBrowse link
G Syt7 synaptotagmin 7 involved_in IMP
ISO		 (MGI:5780544|PMID:12860971) RGD PMID:12860971 PMID:10725327 PMID:20016973 MGI:5780544, RGD:2311145, RGD:7241272 NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026 		JBrowse link
G Syt9 synaptotagmin 9 involved_in IMP
ISO
IEA		 (PMID:12860971)
GO_REF:0000107
(MGI:5780544|PMID:12860971)		 RGD
Ensembl		 PMID:12860971 PMID:11751925 PMID:15015935 PMID:17686463 GO_REF:0000107 MGI:5780544, RGD:2311146, RGD:7241274, RGD:7205657 NCBI chr 1:161,275,882...161,456,384
Ensembl chr 1:161,275,734...161,455,007 		JBrowse link
regulation of calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21106823)		 Ensembl
RGD		 PMID:21106823 GO_REF:0000107 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3652690|PMID:16782817)		 ParkinsonsUK-UCL
RGD		 PMID:16782817 GO_REF:0000024 MGI:3652690 NCBI chr13:39,355,698...39,429,154
Ensembl chr13:39,352,247...39,429,169 		JBrowse link
regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baiap3 BAI1-associated protein 3 involved_in ISO
IBA		 (PMID:28626000)
GO_REF:0000033		 RGD
GO_Central		 PMID:28626000 GO_REF:0000033 NCBI chr10:14,260,269...14,273,019
Ensembl chr10:14,260,269...14,273,019 		JBrowse link
regulation of postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 involved_in ISO (PMID:19448629) RGD PMID:19448629 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2rx7 purinergic receptor P2X 7 involved_in EXP
IDA		 PMID:24037803 SynGO PMID:24037803 PMID:24037803 RGD:13702177, RGD:13702177 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in IDA
IMP		 PMID:14627637 SynGO PMID:14627637 PMID:14627637 RGD:8554199, RGD:8554199 NCBI chr 7:14,521,448...14,534,589
Ensembl chr 7:14,521,368...14,534,593 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in IEA
ISO		 GO_REF:0000107
(PMID:31679900)		 Ensembl
RGD		 PMID:31679900 GO_REF:0000107 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336 		JBrowse link
G Unc13b unc-13 homolog B involved_in IMP
IEP
IDA		 PMID:31679900 SynGO PMID:31679900 PMID:31679900 PMID:31679900 RGD:155230690, RGD:155230690, RGD:155230690 NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926 		JBrowse link
zymogen granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sdf4 stromal cell derived factor 4 involved_in IMP PMID:17442889 BHF-UCL PMID:17442889 RGD:2312426 NCBI chr 5:166,586,581...166,606,661
Ensembl chr 5:166,586,390...166,604,521 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 acts_upstream_of_or_within ISO MGI:3056083 (PMID:18535671) RGD PMID:18535671 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20133
    cellular process 19325
      vesicle-mediated transport 1638
        exocytosis 407
          regulated exocytosis 280
            calcium-ion regulated exocytosis 83
              acrosomal vesicle exocytosis + 9
              calcium ion regulated lysosome exocytosis 3
              calcium ion-regulated exocytosis of neurotransmitter + 26
              cortical granule exocytosis + 2
              dense core granule exocytosis + 16
              negative regulation of calcium ion-dependent exocytosis + 11
              positive regulation of calcium ion-dependent exocytosis + 19
              regulation of calcium ion-dependent exocytosis + 45
              zymogen granule exocytosis 2
Path 2
Term Annotations click to browse term
  biological_process 20133
    localization 5688
      establishment of localization 4991
        transport 4684
          secretion 1208
            secretion by cell 1013
              exocytosis 407
                regulated exocytosis 280
                  calcium-ion regulated exocytosis 83
                    acrosomal vesicle exocytosis + 9
                    calcium ion regulated lysosome exocytosis 3
                    calcium ion-regulated exocytosis of neurotransmitter + 26
                    cortical granule exocytosis + 2
                    dense core granule exocytosis + 16
                    negative regulation of calcium ion-dependent exocytosis + 11
                    positive regulation of calcium ion-dependent exocytosis + 19
                    regulation of calcium ion-dependent exocytosis + 45
                    zymogen granule exocytosis 2
paths to the root