Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:calcium-ion regulated exocytosis
go back to main search page
Accession:GO:0017156 term browser browse the term
Definition:The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.
Comment:Note that the calcium regulated exocytosis pathway can be leaky: some level of exocytosis via this pathway occurs spontaneously. This phenomenon underlies spontaneous neurotransmitter release from presynapses. This phenomenon is distinct from the unregulated, calcium independent exocytosis pathway.
Synonyms:exact_synonym: calcium ion-dependent exocytosis


show annotations for term's descendants           Sort by:
 
calcium-ion regulated exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap17 Rho GTPase activating protein 17 IDA
IBA
PMID:10967100
PMID:21873635
MGI
GO_Central
PMID:10967100, PMID:21873635 RGD:633422, RGD:13792537 NCBI chr 1:193,239,036...193,328,425
Ensembl chr 1:193,239,040...193,328,371
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO MGI:MGI:2181384 (MGI:MGI:2180460|PMID:12065603) RGD PMID:12065603 MGI:MGI:2180460 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO MGI:MGI:2176227|MGI:MGI:2674119 (MGI:MGI:2670808|PMID:12881419) RGD PMID:12881419 MGI:MGI:2670808 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5306323|PMID:11978799)
Ensembl
UniProt
RGD
PMID:11978799 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5306323 NCBI chr15:4,209,702...4,236,895
Ensembl chr15:4,209,703...4,236,895
JBrowse link
G Rab3a RAB3A, member RAS oncogene family ISO (MGI:MGI:4830800|PMID:20338242) RGD PMID:20338242 MGI:MGI:4830800 NCBI chr16:20,435,098...20,439,206
Ensembl chr16:20,435,101...20,439,206
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 ISO
IEA
(MGI:MGI:2151174|PMID:11056535)
GO_REF:0000107
RGD
Ensembl
PMID:11056535 GO_REF:0000107, MGI:MGI:2151174 NCBI chr 3:58,632,338...58,925,127
Ensembl chr 3:58,632,476...58,924,038
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 ISO
ISS
(MGI:MGI:2151174|PMID:11056535)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:11056535 GO_REF:0000024, MGI:MGI:2151174 NCBI chr 7:78,091,998...78,594,164
Ensembl chr 7:78,092,037...78,594,138
JBrowse link
G Rims3 regulating synaptic membrane exocytosis 3 IDA RGD PMID:10748113 RGD:633421 NCBI chr 5:139,790,395...139,819,014
Ensembl chr 5:139,783,951...139,819,016
JBrowse link
G Sdf4 stromal cell derived factor 4 IMP
IBA
PMID:17442889
PMID:21873635
BHF-UCL
GO_Central
PMID:17442889, PMID:21873635 RGD:2312426, RGD:13792537 NCBI chr 5:173,425,922...173,444,478
Ensembl chr 5:173,425,907...173,444,620
JBrowse link
G Stx1a syntaxin 1A ISO (MGI:MGI:3703420|PMID:10468580) RGD PMID:10468580 MGI:MGI:3703420 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019
JBrowse link
G Syn2 synapsin II IEA
ISO
GO_REF:0000107
(MGI:MGI:4830800|PMID:20338242)
Ensembl
RGD
PMID:20338242 GO_REF:0000107, MGI:MGI:4830800 NCBI chr 4:147,037,179...147,195,096
Ensembl chr 4:147,037,179...147,195,096
JBrowse link
G Syt1 synaptotagmin 1 TAS
IBA
PMID:21873635 RGD
GO_Central
PMID:2333096, PMID:21873635 RGD:729959, RGD:13792537 NCBI chr 7:50,084,063...50,638,996
Ensembl chr 7:50,084,060...50,638,798
JBrowse link
G Syt10 synaptotagmin 10 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:130,769,039...130,827,030
Ensembl chr 7:130,768,841...130,827,152
JBrowse link
G Syt11 synaptotagmin 11 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link
G Syt12 synaptotagmin 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:219,690,013...219,719,359
Ensembl chr 1:219,688,451...219,719,272
JBrowse link
G Syt13 synaptotagmin 13 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:81,814,287...81,852,454
Ensembl chr 3:81,814,261...81,854,605
JBrowse link
G Syt15 synaptotagmin 15 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:10,554,136...10,564,934
Ensembl chr16:10,554,136...10,564,927
JBrowse link
G Syt17 synaptotagmin 17 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:188,034,614...188,101,590
Ensembl chr 1:188,034,495...188,101,566
JBrowse link
G Syt2 synaptotagmin 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:51,569,248...51,577,824
Ensembl chr13:51,534,025...51,578,052
JBrowse link
G Syt3 synaptotagmin 3 TAS
IBA
IEA
PMID:21873635
GO_REF:0000002
InterPro PMID:7791877, PMID:21873635 GO_REF:0000002, RGD:61762, RGD:13792537 NCBI chr 1:100,379,236...100,407,862
Ensembl chr 1:100,379,186...100,408,083
JBrowse link
G Syt4 synaptotagmin 4 NAS
IBA
PMID:21873635 RGD
GO_Central
PMID:7892240, PMID:21873635 RGD:730180, RGD:13792537 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012
JBrowse link
G Syt5 synaptotagmin 5 NAS
IBA
PMID:21873635 RGD
GO_Central
PMID:12006594, PMID:21873635 RGD:730140, RGD:13792537 NCBI chr 1:72,859,806...72,867,934
Ensembl chr 1:72,860,218...72,867,930
JBrowse link
G Syt6 synaptotagmin 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:206,064,181...206,119,034
Ensembl chr 2:206,064,179...206,127,907
JBrowse link
G Syt7 synaptotagmin 7 IDA
IBA
PMID:11395007
PMID:21873635
UniProt
GO_Central
PMID:11395007, PMID:21873635 RGD:634203, RGD:13792537 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377
JBrowse link
G Syt7_v1 synaptotagmin 7, variant 1 TAS RGD PMID:12071850 RGD:619692
G Syt7_v2 synaptotagmin 7, variant 2 TAS RGD PMID:12071850 RGD:619692
G Syt7_v3 synaptotagmin 7, variant 3 TAS RGD PMID:12071850 RGD:619692
G Syt8 synaptotagmin 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:215,605,408...215,607,602
Ensembl chr 1:215,605,404...215,607,696
JBrowse link
G Syt9 synaptotagmin 9 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:171,592,703...171,769,780
Ensembl chr 1:171,592,797...171,769,780
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 ISO MGI:MGI:2179745 (MGI:MGI:2384381|PMID:12145198), (MGI:MGI:3589987|PMID:15920476) RGD PMID:12145198, PMID:15920476 MGI:MGI:2384381, MGI:MGI:3589987 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
G Vamp3 vesicle-associated membrane protein 3 ISO MGI:MGI:2385941 (MGI:MGI:3589987|PMID:15920476) RGD PMID:15920476 MGI:MGI:3589987 NCBI chr 5:168,126,157...168,136,628
Ensembl chr 5:168,126,157...168,136,666
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 IDA PMID:14993220 UniProt PMID:14993220 RGD:8553828 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381
JBrowse link
acrosomal vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eqtn equatorin ISO
IBA
(MGI:MGI:5293452|PMID:19285662)
PMID:21873635
RGD PMID:19285662, PMID:21873635 MGI:MGI:5293452, RGD:13792537 NCBI chr 5:113,852,191...113,881,142
Ensembl chr 5:113,871,230...113,880,911
JBrowse link
G Rab3a RAB3A, member RAS oncogene family ISO (PMID:22248876) RGD PMID:22248876 NCBI chr16:20,435,098...20,439,206
Ensembl chr16:20,435,101...20,439,206
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 IEA
ISO
GO_REF:0000107
(PMID:22248876)
Ensembl
RGD
PMID:22248876 GO_REF:0000107 NCBI chr 9:28,440,408...28,973,246
Ensembl chr 9:28,442,229...28,973,246
JBrowse link
G Syt6 synaptotagmin 6 ISO (PMID:11437455) RGD PMID:11437455 NCBI chr 2:206,064,181...206,119,034
Ensembl chr 2:206,064,179...206,127,907
JBrowse link
G Unc13b unc-13 homolog B IEA
ISO
GO_REF:0000107
(PMID:22248876)
Ensembl
RGD
PMID:22248876 GO_REF:0000107 NCBI chr 5:58,505,449...58,714,396
Ensembl chr 5:58,505,500...58,715,576
JBrowse link
G Zp4 zona pellucida glycoprotein 4 IEA
ISO
GO_REF:0000107
(PMID:19004505)
Ensembl
RGD
PMID:19004505 GO_REF:0000107 NCBI chr17:65,497,359...65,503,912
Ensembl chr17:65,497,359...65,503,912
JBrowse link
calcium ion regulated lysosome exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt11 synaptotagmin 11 ISO (MGI:MGI:5788615|PMID:26450452) RGD PMID:26450452 MGI:MGI:5788615 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link
G Syt7 synaptotagmin 7 IDA
ISO
PMID:10725327
(MGI:MGI:3690533|PMID:16982801), (MGI:MGI:3798323|PMID:18539119)
PMID:11511344
RGD PMID:16982801, PMID:18539119, PMID:10725327, PMID:11511344 MGI:MGI:3690533, MGI:MGI:3798323, RGD:2311145, RGD:11041027 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377
JBrowse link
calcium ion-regulated exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO
IEA
MGI:MGI:1856209 (MGI:MGI:1353373|PMID:10670432)
GO_REF:0000107
RGD
Ensembl
PMID:10670432 GO_REF:0000107, MGI:MGI:1353373 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Doc2b double C2 domain beta IDA
ISO
IEA
PMID:20150444
(MGI:MGI:4439222|PMID:20150444)
GO_REF:0000107
RGD
Ensembl
PMID:20150444, PMID:20150444 GO_REF:0000107, MGI:MGI:4439222, RGD:8554647 NCBI chr10:63,921,255...63,952,944
Ensembl chr10:63,928,064...63,952,726
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 ISO
IBA
MGI:MGI:2152972 (MGI:MGI:3703478|PMID:17124501)
PMID:21873635
RGD PMID:17124501, PMID:21873635 MGI:MGI:3703478, RGD:13792537 NCBI chr 9:28,440,408...28,973,246
Ensembl chr 9:28,442,229...28,973,246
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 ISO
IBA
ISS
IEA
MGI:MGI:2152971 (MGI:MGI:3703478|PMID:17124501)
PMID:21873635
GO_REF:0000024
GO_REF:0000002
RGD
ParkinsonsUK-UCL
InterPro
PMID:17124501, PMID:21873635 GO_REF:0000002, GO_REF:0000024, MGI:MGI:3703478, RGD:13792537 NCBI chr 7:78,091,998...78,594,164
Ensembl chr 7:78,092,037...78,594,138
JBrowse link
G Rims3 regulating synaptic membrane exocytosis 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:139,790,395...139,819,014
Ensembl chr 5:139,783,951...139,819,016
JBrowse link
G Snap25 synaptosome associated protein 25 IDA RGD PMID:14980208 RGD:1581082 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400
JBrowse link
G Stx1b syntaxin 1B ISO (MGI:MGI:3803800|PMID:18703708) RGD PMID:18703708 MGI:MGI:3803800 NCBI chr 1:199,251,842...199,270,465
Ensembl chr 1:199,251,844...199,270,627
JBrowse link
G Syt1 synaptotagmin 1 ISO
IBA
MGI:MGI:1857252 (MGI:MGI:5141208|PMID:21521611)
PMID:21873635
RGD PMID:21521611, PMID:21873635 MGI:MGI:5141208, RGD:13792537 NCBI chr 7:50,084,063...50,638,996
Ensembl chr 7:50,084,060...50,638,798
JBrowse link
G Syt10 synaptotagmin 10 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:130,769,039...130,827,030
Ensembl chr 7:130,768,841...130,827,152
JBrowse link
G Syt12 synaptotagmin 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:219,690,013...219,719,359
Ensembl chr 1:219,688,451...219,719,272
JBrowse link
G Syt17 synaptotagmin 17 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:188,034,614...188,101,590
Ensembl chr 1:188,034,495...188,101,566
JBrowse link
G Syt2 synaptotagmin 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:51,569,248...51,577,824
Ensembl chr13:51,534,025...51,578,052
JBrowse link
G Syt3 synaptotagmin 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:100,379,236...100,407,862
Ensembl chr 1:100,379,186...100,408,083
JBrowse link
G Syt5 synaptotagmin 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:72,859,806...72,867,934
Ensembl chr 1:72,860,218...72,867,930
JBrowse link
G Syt6 synaptotagmin 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:206,064,181...206,119,034
Ensembl chr 2:206,064,179...206,127,907
JBrowse link
G Syt7 synaptotagmin 7 ISO
ISS
(MGI:MGI:5707519|PMID:26738595)
GO_REF:0000024
RGD
UniProt
PMID:26738595 GO_REF:0000024, MGI:MGI:5707519 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377
JBrowse link
G Syt8 synaptotagmin 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:215,605,408...215,607,602
Ensembl chr 1:215,605,404...215,607,696
JBrowse link
G Syt9 synaptotagmin 9 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:171,592,703...171,769,780
Ensembl chr 1:171,592,797...171,769,780
JBrowse link
dense core granule docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A NOT ISO UniProtKB:Q9Z1N9 (MGI:MGI:5819330|PMID:26575293) RGD PMID:26575293 MGI:MGI:5819330 NCBI chr16:20,056,398...20,103,951
Ensembl chr16:20,056,765...20,097,287
JBrowse link
G Unc13b unc-13 homolog B NOT ISO UniProtKB:Q4KUS2 (MGI:MGI:5819330|PMID:26575293) RGD PMID:26575293 MGI:MGI:5819330 NCBI chr 5:58,505,449...58,714,396
Ensembl chr 5:58,505,500...58,715,576
JBrowse link
dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadps2 calcium dependent secretion activator 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:50,326,447...50,861,161
Ensembl chr 4:50,326,442...50,860,756
JBrowse link
dense core granule priming term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A IGI
IBA
PMID:26575293
PMID:21873635
SynGO-UCL
GO_Central
PMID:26575293, PMID:21873635 RGD:12050107, RGD:13792537 NCBI chr16:20,056,398...20,103,951
Ensembl chr16:20,056,765...20,097,287
JBrowse link
G Unc13b unc-13 homolog B IGI
IBA
PMID:26575293
PMID:21873635
SynGO-UCL
GO_Central
PMID:26575293, PMID:21873635 RGD:12050107, RGD:13792537 NCBI chr 5:58,505,449...58,714,396
Ensembl chr 5:58,505,500...58,715,576
JBrowse link
G Unc13c unc-13 homolog C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:80,202,736...80,656,363
Ensembl chr 8:80,203,609...80,631,926
JBrowse link
G Unc13d unc-13 homolog D IGI PMID:26575293 SynGO-UCL PMID:26575293 RGD:12050107 NCBI chr10:104,613,907...104,628,664
Ensembl chr10:104,613,928...104,628,676
JBrowse link
fast, calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt1 synaptotagmin 1 ISS
ISO
GO_REF:0000024
(MGI:MGI:3040539|PMID:12526776), (MGI:MGI:3653150|PMID:9194562), (MGI:MGI:69538|PMID:7954835)
ParkinsonsUK-UCL
RGD
PMID:7954835, PMID:9194562, PMID:12526776 GO_REF:0000024, MGI:MGI:3040539, MGI:MGI:3653150, MGI:MGI:69538 NCBI chr 7:50,084,063...50,638,996
Ensembl chr 7:50,084,060...50,638,798
JBrowse link
negative regulation of calcium ion-dependent exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A IMP PMID:19965390 BHF-UCL PMID:19965390 RGD:2316628 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein ISO
IBA
(MGI:MGI:5607190|PMID:24751537)
PMID:21873635
RGD PMID:24751537, PMID:21873635 MGI:MGI:5607190, RGD:13792537 NCBI chr 7:12,433,422...12,441,048
Ensembl chr 7:12,433,933...12,441,048
JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:11533141 RGD:13508598 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Notch1 notch receptor 1 ISO MGI:MGI:2684314 (MGI:MGI:3841508|PMID:19251639) RGD PMID:19251639 MGI:MGI:3841508 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Pou5f1 POU class 5 homeobox 1 ISO (MGI:MGI:59016|PMID:2357966) RGD PMID:2357966 MGI:MGI:59016 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IC PMID:19965390 BHF-UCL PMID:19965390 RGD:2316628 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family ISO MGI:MGI:97852 (MGI:MGI:5490391|PMID:23616533) RGD PMID:23616533 MGI:MGI:5490391 NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990
JBrowse link
G Rest RE1-silencing transcription factor IMP PMID:21536750 UniProt PMID:21536750 RGD:8554180 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
G Stxbp3 syntaxin binding protein 3 ISO (PMID:12649283) RGD PMID:12649283 NCBI chr 2:211,595,763...211,638,756
Ensembl chr 2:211,595,659...211,638,788
JBrowse link
G Syt4 synaptotagmin 4 IDA RGD PMID:21551071 RGD:7205660 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012
JBrowse link
G Trim9 tripartite motif-containing 9 IMP RGD PMID:11524423 RGD:631246 NCBI chr 6:92,660,026...92,760,036
Ensembl chr 6:92,660,505...92,760,018
JBrowse link
negative regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 IMP PMID:20303854 ParkinsonsUK-UCL PMID:20303854 RGD:11541109 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012
JBrowse link
neuronal dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A ISS
ISO
GO_REF:0000024
(MGI:MGI:5476894|PMID:23229896)
UniProt
RGD
PMID:23229896 GO_REF:0000024, MGI:MGI:5476894 NCBI chr16:20,056,398...20,103,951
Ensembl chr16:20,056,765...20,097,287
JBrowse link
G Unc13b unc-13 homolog B ISS
ISO
GO_REF:0000024
(MGI:MGI:5476894|PMID:23229896)
UniProt
RGD
PMID:23229896 GO_REF:0000024, MGI:MGI:5476894 NCBI chr 5:58,505,449...58,714,396
Ensembl chr 5:58,505,500...58,715,576
JBrowse link
positive regulation of acrosomal vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyal3 hyaluronidase 3 IEA
ISO
ISS
GO_REF:0000107
(MGI:MGI:4834982|PMID:20586096)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:20586096 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4834982 NCBI chr 8:116,336,512...116,342,147
Ensembl chr 8:116,336,512...116,342,146
JBrowse link
G Zp3 zona pellucida glycoprotein 3 ISS
ISO
GO_REF:0000024
(PMID:19004505), (PMID:19246320)
UniProt
RGD
PMID:19004505, PMID:19246320 GO_REF:0000024 NCBI chr12:23,735,225...23,752,734
Ensembl chr12:23,735,223...23,742,190
JBrowse link
positive regulation of calcium ion-dependent exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP-ribosylation factor 1 IDA RGD PMID:10657240 RGD:9684853 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:17172292, PMID:21873635 RGD:2316206, RGD:13792537 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283
JBrowse link
G Cadps calcium dependent secretion activator IMP RGD PMID:9289490 RGD:1299539 NCBI chr15:15,275,489...15,690,575
Ensembl chr15:15,275,541...15,667,778
JBrowse link
G Cdk5 cyclin-dependent kinase 5 ISO (MGI:MGI:3709145|PMID:15123626) RGD PMID:15123626 MGI:MGI:3709145 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cdk5r2 cyclin-dependent kinase 5 regulatory subunit 2 ISO (MGI:MGI:3709145|PMID:15123626) RGD PMID:15123626 MGI:MGI:3709145 NCBI chr 9:82,120,059...82,121,527
Ensembl chr 9:82,120,059...82,121,527
JBrowse link
G Cltrn collectrin, amino acid transport regulator ISO
IBA
(PMID:16330323)
PMID:21873635
RGD PMID:16330323, PMID:21873635 RGD:13792537 NCBI chr  X:32,118,082...32,153,687
Ensembl chr  X:32,118,054...32,153,794
JBrowse link
G Doc2b double C2 domain beta IDA
IEA
PMID:18596155
GO_REF:0000002
InterPro PMID:18596155 GO_REF:0000002, RGD:8554556 NCBI chr10:63,921,255...63,952,944
Ensembl chr10:63,928,064...63,952,726
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 IDA PMID:17301173
PMID:20484665
PMID:18167541
UniProt PMID:17301173, PMID:20484665, PMID:18167541 RGD:10047384, RGD:10047179, RGD:10047360 NCBI chr 3:163,850,785...163,935,610
Ensembl chr 3:163,850,785...163,935,617
JBrowse link
G Scamp5 secretory carrier membrane protein 5 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19234194)
Ensembl
UniProt
RGD
PMID:19234194 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:62,221,820...62,266,269
Ensembl chr 8:62,220,892...62,248,017
JBrowse link
G Stx1a syntaxin 1A IDA PMID:17301173
PMID:20484665
PMID:18167541
UniProt PMID:17301173, PMID:20484665, PMID:18167541 RGD:10047384, RGD:10047179, RGD:10047360 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019
JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO (MGI:MGI:3709145|PMID:15123626) RGD PMID:15123626 MGI:MGI:3709145 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
G Syt1 synaptotagmin 1 IDA RGD PMID:21551071 RGD:7205660 NCBI chr 7:50,084,063...50,638,996
Ensembl chr 7:50,084,060...50,638,798
JBrowse link
G Syt10 synaptotagmin 10 ISO
ISS
(MGI:MGI:5751674|PMID:21496647)
GO_REF:0000024
RGD
UniProt
PMID:21496647 GO_REF:0000024, MGI:MGI:5751674 NCBI chr 7:130,769,039...130,827,030
Ensembl chr 7:130,768,841...130,827,152
JBrowse link
G Syt7 synaptotagmin 7 IDA RGD PMID:21551071 RGD:7205660 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377
JBrowse link
G Syt9 synaptotagmin 9 IDA RGD PMID:21551071 RGD:7205660 NCBI chr 1:171,592,703...171,769,780
Ensembl chr 1:171,592,797...171,769,780
JBrowse link
positive regulation of calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt1 synaptotagmin 1 ISS
ISO
GO_REF:0000024
(MGI:MGI:2179533|PMID:11242035)
UniProt
RGD
PMID:11242035 GO_REF:0000024, MGI:MGI:2179533 NCBI chr 7:50,084,063...50,638,996
Ensembl chr 7:50,084,060...50,638,798
JBrowse link
positive regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 ISO (MGI:MGI:3795609|PMID:18468511) RGD PMID:18468511 MGI:MGI:3795609 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012
JBrowse link
presynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadps calcium dependent secretion activator IEA
ISO
GO_REF:0000107
UniProtKB:Q8BYR5 (MGI:MGI:5634021|PMID:25719439)
Ensembl
RGD
PMID:25719439 GO_REF:0000107, MGI:MGI:5634021 NCBI chr15:15,275,489...15,690,575
Ensembl chr15:15,275,541...15,667,778
JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO (MGI:MGI:3621672|PMID:11545717) RGD PMID:11545717 MGI:MGI:3621672 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
G Unc13a unc-13 homolog A IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
UniProtKB:Q9Z1N9 (MGI:MGI:5819330|PMID:26575293)
Ensembl
RGD
PMID:26575293, PMID:21873635 GO_REF:0000107, MGI:MGI:5819330, RGD:13792537 NCBI chr16:20,056,398...20,103,951
Ensembl chr16:20,056,765...20,097,287
JBrowse link
G Unc13b unc-13 homolog B ISO
IBA
(MGI:MGI:5819330|PMID:26575293)
PMID:21873635
RGD PMID:26575293, PMID:21873635 MGI:MGI:5819330, RGD:13792537 NCBI chr 5:58,505,449...58,714,396
Ensembl chr 5:58,505,500...58,715,576
JBrowse link
G Unc13c unc-13 homolog C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:80,202,736...80,656,363
Ensembl chr 8:80,203,609...80,631,926
JBrowse link
regulation of acrosomal vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stxbp1 syntaxin binding protein 1 ISO (PMID:23091057) RGD PMID:23091057 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
regulation of calcium ion-dependent exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO
IEA
(MGI:MGI:79428|PMID:8632762)
GO_REF:0000107
RGD
Ensembl
PMID:8632762 GO_REF:0000107, MGI:MGI:79428 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Doc2a double C2 domain alpha ISO (PMID:18354201)
(MGI:MGI:3778349|PMID:18354201)
RGD PMID:18354201 MGI:MGI:3778349 NCBI chr 1:198,282,828...198,288,611
Ensembl chr 1:198,284,473...198,288,113
JBrowse link
G Rph3al rabphilin 3A-like (without C2 domains) ISO MGI:MGI:3051976 (MGI:MGI:3044444|PMID:15159548) RGD PMID:15159548 MGI:MGI:3044444 NCBI chr10:63,989,556...64,140,584
Ensembl chr10:63,989,644...64,108,554
JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 TAS PMID:9704016 UniProt PMID:9704016 RGD:70020 NCBI chr 1:219,964,429...220,006,811
Ensembl chr 1:219,964,429...220,005,068
JBrowse link
G Sycn syncollin TAS RGD PMID:9244306 RGD:634177 NCBI chr 1:85,219,827...85,220,239
Ensembl chr 1:85,218,803...85,220,237
JBrowse link
G Syt1 synaptotagmin 1 IMP
IBA
ISO
PMID:21873635
PMID:12860971
(MGI:MGI:3761204|PMID:11562488)
RGD PMID:11562488, PMID:11751925, PMID:21873635, PMID:12860971, PMID:17686463 MGI:MGI:3761204, RGD:2311146, RGD:13792537, RGD:11079189, RGD:7205657 NCBI chr 7:50,084,063...50,638,996
Ensembl chr 7:50,084,060...50,638,798
JBrowse link
G Syt10 synaptotagmin 10 ISO
IBA
(MGI:MGI:5780544|PMID:12860971)
PMID:21873635
RGD PMID:12860971, PMID:21873635 MGI:MGI:5780544, RGD:13792537 NCBI chr 7:130,769,039...130,827,030
Ensembl chr 7:130,768,841...130,827,152
JBrowse link
G Syt11 synaptotagmin 11 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link
G Syt12 synaptotagmin 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:219,690,013...219,719,359
Ensembl chr 1:219,688,451...219,719,272
JBrowse link
G Syt13 synaptotagmin 13 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:81,814,287...81,852,454
Ensembl chr 3:81,814,261...81,854,605
JBrowse link
G Syt15 synaptotagmin 15 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:10,554,136...10,564,934
Ensembl chr16:10,554,136...10,564,927
JBrowse link
G Syt17 synaptotagmin 17 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:188,034,614...188,101,590
Ensembl chr 1:188,034,495...188,101,566
JBrowse link
G Syt2 synaptotagmin 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:51,569,248...51,577,824
Ensembl chr13:51,534,025...51,578,052
JBrowse link
G Syt3 synaptotagmin 3 IMP
IBA
PMID:12860971
PMID:21873635
ParkinsonsUK-UCL
GO_Central
PMID:12860971, PMID:21873635 RGD:11079189, RGD:13792537 NCBI chr 1:100,379,236...100,407,862
Ensembl chr 1:100,379,186...100,408,083
JBrowse link
G Syt4 synaptotagmin 4 ISO
IBA
(MGI:MGI:3836866|PMID:19136969), (MGI:MGI:4421257|PMID:20010821)
PMID:21873635
RGD PMID:19136969, PMID:20010821, PMID:21873635 MGI:MGI:3836866, MGI:MGI:4421257, RGD:13792537 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012
JBrowse link
G Syt5 synaptotagmin 5 ISO
IBA
(MGI:MGI:5780544|PMID:12860971)
PMID:21873635
RGD PMID:12860971, PMID:21873635 MGI:MGI:5780544, RGD:13792537 NCBI chr 1:72,859,806...72,867,934
Ensembl chr 1:72,860,218...72,867,930
JBrowse link
G Syt6 synaptotagmin 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:206,064,181...206,119,034
Ensembl chr 2:206,064,179...206,127,907
JBrowse link
G Syt7 synaptotagmin 7 IMP
IBA
ISO
PMID:21873635
(MGI:MGI:5780544|PMID:12860971)
RGD PMID:12860971, PMID:10725327, PMID:21873635, PMID:20016973 MGI:MGI:5780544, RGD:2311145, RGD:13792537, RGD:7241272 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377
JBrowse link
G Syt8 synaptotagmin 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:215,605,408...215,607,602
Ensembl chr 1:215,605,404...215,607,696
JBrowse link
G Syt9 synaptotagmin 9 IMP
IBA
ISO
PMID:21873635
(MGI:MGI:5780544|PMID:12860971)
RGD PMID:12860971, PMID:11751925, PMID:21873635, PMID:15015935, PMID:17686463 MGI:MGI:5780544, RGD:2311146, RGD:13792537, RGD:7241274, RGD:7205657 NCBI chr 1:171,592,703...171,769,780
Ensembl chr 1:171,592,797...171,769,780
JBrowse link
regulation of calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO (MGI:MGI:4866942|PMID:21106823) RGD PMID:21106823 MGI:MGI:4866942 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 ISO
ISS
(MGI:MGI:3652690|PMID:16782817)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:16782817 GO_REF:0000024, MGI:MGI:3652690 NCBI chr13:44,578,208...44,649,876
Ensembl chr13:44,615,553...44,648,620
JBrowse link
regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baiap3 BAI1-associated protein 3 ISO (PMID:28626000) RGD PMID:28626000 NCBI chr10:14,601,133...14,613,881
Ensembl chr10:14,599,197...14,613,878
JBrowse link
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2rx7 purinergic receptor P2X 7 EXP
IDA
PMID:24037803 SynGO PMID:24037803, PMID:24037803 RGD:13702177, RGD:13702177 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Syt4 synaptotagmin 4 ISO (MGI:MGI:4457852|PMID:19448629) RGD PMID:19448629 MGI:MGI:4457852 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012
JBrowse link
zymogen granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sdf4 stromal cell derived factor 4 IMP PMID:17442889 BHF-UCL PMID:17442889 RGD:2312426 NCBI chr 5:173,425,922...173,444,478
Ensembl chr 5:173,425,907...173,444,620
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 ISO MGI:MGI:3056083 (MGI:MGI:3801544|PMID:18535671) RGD PMID:18535671 MGI:MGI:3801544 NCBI chr 4:100,250,301...100,252,756
Ensembl chr 4:100,250,301...100,252,755
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      vesicle-mediated transport 1652
        exocytosis 414
          regulated exocytosis 279
            calcium-ion regulated exocytosis 75
              acrosomal vesicle exocytosis + 9
              calcium ion regulated lysosome exocytosis 2
              calcium ion-regulated exocytosis of neurotransmitter + 27
              cortical granule exocytosis + 0
              dense core granule exocytosis + 10
              negative regulation of calcium ion-dependent exocytosis + 11
              positive regulation of calcium ion-dependent exocytosis + 20
              regulation of calcium ion-dependent exocytosis + 49
              zymogen granule exocytosis 2
Path 2
Term Annotations click to browse term
  biological_process 20014
    localization 6486
      establishment of localization 4918
        transport 4774
          secretion 1217
            secretion by cell 1020
              exocytosis 414
                regulated exocytosis 279
                  calcium-ion regulated exocytosis 75
                    acrosomal vesicle exocytosis + 9
                    calcium ion regulated lysosome exocytosis 2
                    calcium ion-regulated exocytosis of neurotransmitter + 27
                    cortical granule exocytosis + 0
                    dense core granule exocytosis + 10
                    negative regulation of calcium ion-dependent exocytosis + 11
                    positive regulation of calcium ion-dependent exocytosis + 20
                    regulation of calcium ion-dependent exocytosis + 49
                    zymogen granule exocytosis 2
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.