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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA dihydrouridine synthase activity
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Accession:GO:0017150 term browser browse the term
Definition:Catalysis of the reaction: a 5,6-dihydrouridine in tRNA + NAD(P)+ = a uridine in tRNA + H+ + NAD(P)H.
Synonyms:xref: reactome:R-HSA-6782296 "DUS2:EPRS reduces uridine to dihydrouridine in tRNAs"


show annotations for term's descendants           Sort by:
tRNA dihydrouridine synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus1l dihydrouridine synthase 1-like enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:106,553,841...106,560,977
Ensembl chr10:106,553,238...106,561,285 		JBrowse link
G Dus2 dihydrouridine synthase 2 enables ISO
IEA 		(PMID:26429968)
GO_REF:0000002 		RGD
InterPro		 PMID:26429968 GO_REF:0000002 NCBI chr19:50,816,306...50,864,559
Ensembl chr19:50,816,310...50,864,559 		JBrowse link
G Dus3l dihydrouridine synthase 3-like enables IEA
IBA 		GO_REF:0000104
GO_REF:0000002
GO_REF:0000033 		UniProt
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 9:1,680,619...1,685,784
Ensembl chr 9:1,675,819...1,686,367 		JBrowse link
G Dus4l dihydrouridine synthase 4-like enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 6:53,955,609...53,970,050
Ensembl chr 6:53,955,609...53,970,087 		JBrowse link
tRNA-dihydrouridine16 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus1l dihydrouridine synthase 1-like enables ISO
IEA
ISS 		(PMID:39354220)
GO_REF:0000116
GO_REF:0000107
GO_REF:0000024 		RGD
RHEA
Ensembl
UniProt		 PMID:39354220 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr10:106,553,841...106,560,977
Ensembl chr10:106,553,238...106,561,285 		JBrowse link
tRNA-dihydrouridine17 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus1l dihydrouridine synthase 1-like enables ISO
ISS
IEA 		(PMID:39354220)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000116 		RGD
UniProt
Ensembl
RHEA		 PMID:39354220 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr10:106,553,841...106,560,977
Ensembl chr10:106,553,238...106,561,285 		JBrowse link
tRNA-dihydrouridine20 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus2 dihydrouridine synthase 2 enables ISO
IEA 		(PMID:38680565)
GO_REF:0000003 		RGD
UniProt		 PMID:38680565 GO_REF:0000003 NCBI chr19:50,816,306...50,864,559
Ensembl chr19:50,816,310...50,864,559 		JBrowse link
tRNA-dihydrouridine20a synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus4l dihydrouridine synthase 4-like enables IEA GO_REF:0000116
GO_REF:0000003 		RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 6:53,955,609...53,970,050
Ensembl chr 6:53,955,609...53,970,087 		JBrowse link
tRNA-dihydrouridine20b synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus4l dihydrouridine synthase 4-like enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 6:53,955,609...53,970,050
Ensembl chr 6:53,955,609...53,970,087 		JBrowse link
tRNA-dihydrouridine47 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus3l dihydrouridine synthase 3-like enables ISO
IEA
ISS 		(PMID:34556860)
GO_REF:0000003
GO_REF:0000117
GO_REF:0000024 		RGD
UniProt		 PMID:34556860 GO_REF:0000003 GO_REF:0000024 GO_REF:0000117 NCBI chr 9:1,680,619...1,685,784
Ensembl chr 9:1,675,819...1,686,367 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19971
    catalytic activity 5918
      catalytic activity, acting on a nucleic acid 681
        catalytic activity, acting on RNA 425
          catalytic activity, acting on a tRNA 155
            tRNA dihydrouridine synthase activity 4
              tRNA-dihydrouridine16 synthase activity 1
              tRNA-dihydrouridine17 synthase activity 1
              tRNA-dihydrouridine20 synthase activity 1
              tRNA-dihydrouridine20a synthase activity 1
              tRNA-dihydrouridine20b synthase activity 1
              tRNA-dihydrouridine47 synthase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 19971
    catalytic activity 5918
      oxidoreductase activity 800
        oxidoreductase activity, acting on the CH-CH group of donors 64
          oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 36
            RNA dihydrouridine synthase activity 4
              tRNA dihydrouridine synthase activity 4
                tRNA-dihydrouridine16 synthase activity 1
                tRNA-dihydrouridine17 synthase activity 1
                tRNA-dihydrouridine20 synthase activity 1
                tRNA-dihydrouridine20a synthase activity 1
                tRNA-dihydrouridine20b synthase activity 1
                tRNA-dihydrouridine47 synthase activity 1
paths to the root