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ONTOLOGY REPORT - ANNOTATIONS


Term:tRNA dihydrouridine synthase activity
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Accession:GO:0017150 term browser browse the term
Definition:Catalysis of the reaction: a 5,6-dihydrouridine in tRNA + NAD(P)+ = a uridine in tRNA + H+ + NAD(P)H.
Synonyms:xref: reactome:R-HSA-6782296 "DUS2:EPRS reduces uridine to dihydrouridine in tRNAs"



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tRNA dihydrouridine synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus1l dihydrouridine synthase 1-like enables IEA
IBA
GO_REF:0000002
GO_REF:0000033
InterPro
GO_Central
GO_REF:0000002 GO_REF:0000033 NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781
JBrowse link
G Dus2 dihydrouridine synthase 2 enables ISO
IBA
(PMID:26429968)
GO_REF:0000033
RGD
GO_Central
PMID:26429968 GO_REF:0000033 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709
JBrowse link
G Dus3l dihydrouridine synthase 3-like enables IEA
IBA
ISO
ISS
GO_REF:0000104
GO_REF:0000033
(PMID:34556860)
GO_REF:0000024
UniProt
GO_Central
RGD
PMID:34556860 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655
JBrowse link
G Dus4l dihydrouridine synthase 4-like enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:48,228,111...48,242,553
Ensembl chr 6:48,228,111...48,242,449
JBrowse link
tRNA-dihydrouridine16 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus1l dihydrouridine synthase 1-like enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781
JBrowse link
tRNA-dihydrouridine17 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus1l dihydrouridine synthase 1-like enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781
JBrowse link
tRNA-dihydrouridine20 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus2 dihydrouridine synthase 2 enables ISO (PMID:38680565) RGD PMID:38680565 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709
JBrowse link
tRNA-dihydrouridine47 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus3l dihydrouridine synthase 3-like enables ISO (PMID:34556860) RGD PMID:34556860 NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20730
    catalytic activity 6116
      catalytic activity, acting on a nucleic acid 633
        catalytic activity, acting on RNA 397
          catalytic activity, acting on a tRNA 136
            tRNA dihydrouridine synthase activity 4
              tRNA-dihydrouridine16 synthase activity 1
              tRNA-dihydrouridine17 synthase activity 1
              tRNA-dihydrouridine20 synthase activity 1
              tRNA-dihydrouridine20a synthase activity 0
              tRNA-dihydrouridine20b synthase activity 0
              tRNA-dihydrouridine47 synthase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 20730
    catalytic activity 6116
      oxidoreductase activity 859
        oxidoreductase activity, acting on the CH-CH group of donors 61
          oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 32
            RNA dihydrouridine synthase activity 4
              tRNA dihydrouridine synthase activity 4
                tRNA-dihydrouridine16 synthase activity 1
                tRNA-dihydrouridine17 synthase activity 1
                tRNA-dihydrouridine20 synthase activity 1
                tRNA-dihydrouridine20a synthase activity 0
                tRNA-dihydrouridine20b synthase activity 0
                tRNA-dihydrouridine47 synthase activity 1
paths to the root