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ONTOLOGY REPORT - ANNOTATIONS


Term:phospholipid scramblase activity
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Accession:GO:0017128 term browser browse the term
Definition:Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism.
Comment:Nomenclature note. Scramblases are ATP-independent, non-selective, translocases inducing non-specific transbilayer movements across the membrane. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases).


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phospholipid scramblase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G 1700057G04Rik RIKEN cDNA 1700057G04 gene JBrowse link 9 92,309,326 92,357,876 RGD:2290270
G Ano1 anoctamin 1, calcium activated chloride channel JBrowse link 7 144,588,549 144,752,026 RGD:2290270
G Ano10 anoctamin 10 JBrowse link 9 122,175,874 122,294,444 RGD:2290270
G Ano2 anoctamin 2 JBrowse link 6 125,690,419 126,040,133 RGD:2290270
G Ano3 anoctamin 3 JBrowse link 2 110,655,201 110,950,391 RGD:2290270
G Ano4 anoctamin 4 JBrowse link 10 88,948,932 89,345,205 RGD:2290270
G Ano5 anoctamin 5 JBrowse link 7 51,510,007 51,598,707 RGD:2290270
G Ano6 anoctamin 6 JBrowse link 15 95,790,843 95,975,472 RGD:2290270
G Ano7 anoctamin 7 JBrowse link 1 93,373,796 93,404,304 RGD:2290270
G Ano8 anoctamin 8 JBrowse link 8 71,476,016 71,486,092 RGD:2290270
G Ano9 anoctamin 9 JBrowse link 7 141,101,212 141,117,806 RGD:2290270
G Plscr1 phospholipid scramblase 1 JBrowse link 9 92,250,194 92,272,561 RGD:2290270
G Plscr2 phospholipid scramblase 2 JBrowse link 9 92,275,602 92,297,752 RGD:2290270
G Plscr3 phospholipid scramblase 3 JBrowse link 11 69,846,372 69,852,058 RGD:2290270
G Plscr4 phospholipid scramblase 4 JBrowse link 9 92,457,372 92,493,513 RGD:2290270
G Plscr5 phospholipid scramblase family, member 5 JBrowse link 9 92,186,516 92,212,536 RGD:2290270

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  molecular_function 22936
    transporter activity 1153
      lipid transporter activity 153
        intramembrane lipid transporter activity 41
          phospholipid scramblase activity 16
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.