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ONTOLOGY REPORT - ANNOTATIONS


Term:acetylserotonin O-methyltransferase activity
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Accession:GO:0017096 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.
Synonyms:related_synonym: N-acetylserotonin O-methyltransferase activity;   S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase activity;   acetylserotonin methyltransferase activity;   hydroxyindole O-methyltransferase activity;   hydroxyindole methyltransferase activity
 alt_id: GO:0017097
 xref: EC:2.1.1.4;   MetaCyc:ACETYLSEROTONIN-O-METHYLTRANSFERASE-RXN;   RHEA:15573



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acetylserotonin O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asmt acetylserotonin O-methyltransferase enables IDA
ISO
IEA
IBA
(PMID:22775292)
GO_REF:0000003
GO_REF:0000033
(PMID:20308563), (PMID:3941912)
RGD
UniProt
GO_Central
PMID:3941912 PMID:20308563 PMID:22775292 PMID:8930356 PMID:12198599 GO_REF:0000003 GO_REF:0000033, RGD:1299464, RGD:1359073 NCBI chr12:16,304,719...16,309,568
Ensembl chr12:16,304,719...16,309,568
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  molecular_function 21086
    catalytic activity 6127
      transferase activity 2447
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            S-adenosylmethionine-dependent methyltransferase activity 169
              acetylserotonin O-methyltransferase activity 1
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