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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of transforming growth factor beta receptor signaling pathway
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Accession:GO:0017015 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
Synonyms:exact_synonym: regulation of TGF-beta receptor signaling pathway;   regulation of TGFbeta receptor signaling pathway;   regulation of transforming growth factor beta receptor signalling pathway



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regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL9 BCL9 transcription coactivator NOT|involved_in ISO (PMID:19328798) BHF-UCL PMID:19328798 NCBI chr 1:122,982,604...123,067,299
Ensembl chr 1:112,463,904...112,478,264
JBrowse link
G CAV3 caveolin 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4946902|PMID:21182936) MGI
Ensembl
PMID:21182936 GO_REF:0000107 MGI:4946902 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 acts_upstream_of_or_within ISO (MGI:1335654|PMID:10208746) MGI PMID:10208746 MGI:1335654 NCBI chr19:12,529,830...12,536,052 JBrowse link
G EID2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) HGNC-UCL PMID:14612439 NCBI chr19:36,636,855...36,638,308 JBrowse link
G ENG endoglin involved_in ISO
IEA
RGD
Ensembl
PMID:17376778 GO_REF:0000107 RGD:2313627 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641
JBrowse link
G FOLR1 folate receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,268,721...67,275,498
Ensembl chr11:70,492,039...70,498,665
JBrowse link
G GDF2 growth differentiation factor 2 NOT|involved_in ISO (MGI:4830635|PMID:20406889) DFLAT PMID:20406889 MGI:4830635 NCBI chr10:46,520,808...46,526,414 JBrowse link
G IL17F interleukin 17F involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,789,210...51,797,470
Ensembl chr 6:53,057,318...53,065,124
JBrowse link
G ITGA3 integrin subunit alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:44,145,974...44,181,343
Ensembl chr17:49,019,892...49,055,245
JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:147,476,913...147,533,491
Ensembl chr 6:152,182,394...152,239,276
JBrowse link
G LATS2 large tumor suppressor kinase 2 involved_in ISO (MGI:4939579|PMID:21145499) UniProt PMID:21145499 MGI:4939579 NCBI chr13:2,300,625...2,389,027
Ensembl chr13:20,611,861...20,683,083
JBrowse link
G LOX lysyl oxidase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5634219|PMID:25715398) MGI
Ensembl
PMID:25715398 GO_REF:0000107 MGI:5634219 NCBI chr 5:117,450,833...117,464,957
Ensembl chr 5:123,234,662...123,248,717
JBrowse link
G NREP neuronal regeneration related protein acts_upstream_of_or_within ISO (MGI:3034115|PMID:14985127) MGI PMID:14985127 MGI:3034115 NCBI chr 5:107,089,968...107,118,919 JBrowse link
G PALS1 protein associated with LIN7 1, MAGUK p55 family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:47,814,896...47,911,206
Ensembl chr14:66,693,863...66,790,122
JBrowse link
G SMAD2 SMAD family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:41,213,001...41,309,902
Ensembl chr18:44,580,905...44,668,530
JBrowse link
G SMAD3 SMAD family member 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2153314|PMID:11711431) MGI
Ensembl
PMID:11711431 GO_REF:0000107 MGI:2153314 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185
JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359
JBrowse link
G SMAD7 SMAD family member 7 ISO RGD PMID:11959632 RGD:625758 NCBI chr18:42,306,324...42,337,214 JBrowse link
G SOX11 SRY-box transcription factor 11 involved_in ISO (PMID:20624318) UniProt PMID:20624318 NCBI chr2A:5,699,738...5,711,210 JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISO (PMID:15334054) BHF-UCL PMID:15334054 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TRIM33 tripartite motif containing 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:88,043,031...88,163,804
Ensembl chr 1:123,095,244...123,210,355
JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3641341|PMID:16824956) MGI
Ensembl
PMID:16824956 GO_REF:0000107 MGI:3641341 NCBI chr10:31,449,202...31,659,534
Ensembl chr10:32,046,491...32,253,550
JBrowse link
G ZNF703 zinc finger protein 703 involved_in ISO (PMID:21337521)
(MGI:4940410|PMID:21317240)
UniProt PMID:21317240 PMID:21337521 MGI:4940410 NCBI chr 8:36,994,222...36,998,462 JBrowse link
G ZNF703 zinc finger protein 703 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 8:34,172,578...34,174,764 JBrowse link
negative regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054
JBrowse link
G ADAMTSL2 ADAMTS like 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5638958|PMID:25762570) MGI
Ensembl
PMID:25762570 GO_REF:0000107 MGI:5638958 NCBI chr 9:104,658,540...104,698,854
Ensembl chr 9:133,269,369...133,309,602
JBrowse link
G ASPN asporin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:63,579,188...63,605,811
Ensembl chr 9:91,651,629...91,677,969
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr10:28,833,690...28,839,164
Ensembl chr10:29,187,857...29,193,324
JBrowse link
G BCL9L BCL9 like involved_in ISO (PMID:19328798) BHF-UCL PMID:19328798 NCBI chr11:113,735,852...113,765,811
Ensembl chr11:117,666,995...117,678,598
JBrowse link
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:28467929) ARUK-UCL
Ensembl
PMID:28467929 GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CAV2 caveolin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5298182|PMID:21832243) MGI
Ensembl
PMID:21832243 GO_REF:0000107 MGI:5298182 NCBI chr 7:108,254,074...108,480,716
Ensembl chr 7:121,168,579...121,177,415
JBrowse link
G CD109 CD109 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:71,519,293...71,654,300
Ensembl chr 6:74,801,384...74,937,414
JBrowse link
G CHST11 carbohydrate sulfotransferase 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3767479|PMID:16079159) MGI
Ensembl
PMID:16079159 GO_REF:0000107 MGI:3767479 NCBI chr12:102,035,480...102,340,084
Ensembl chr12:105,431,075...105,731,172
JBrowse link
G CIDEA cell death inducing DFFA like effector a involved_in ISO (MGI:3768618|PMID:17080483) BHF-UCL PMID:17080483 MGI:3768618 NCBI chr18:2,051,880...2,075,909 JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 acts_upstream_of_or_within ISO (MGI:3055566|PMID:14721776) MGI PMID:14721776 MGI:3055566 NCBI chr19:12,529,830...12,536,052 JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:25100282 RGD:9685289 NCBI chr19:10,272,172...10,386,032
Ensembl chr19:10,933,672...11,106,478
JBrowse link
G EID2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) HGNC-UCL PMID:14612439 NCBI chr19:36,636,855...36,638,308 JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:27,077,551...27,085,437
Ensembl chr2A:27,166,747...27,174,525
JBrowse link
G FAM89B family with sequence similarity 89 member B involved_in ISO (MGI:5486566|PMID:12646588) UniProt PMID:12646588 MGI:5486566 NCBI chr11:60,931,592...60,933,317 JBrowse link
G FKBP1A FKBP prolyl isomerase 1A involved_in ISO (PMID:11583628) FlyBase PMID:11583628 NCBI chr20:1,519,330...1,548,473 JBrowse link
G GLG1 golgi glycoprotein 1 acts_upstream_of_or_within ISO (MGI:4829577|PMID:20530870) MGI PMID:20530870 MGI:4829577 NCBI chr16:55,014,892...55,172,877
Ensembl chr16:74,372,660...74,526,764
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24613385) UniProt PMID:24613385 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 acts_upstream_of_or_within ISO (MGI:3771280|PMID:17991893) MGI PMID:17991893 MGI:3771280 NCBI chr 9:96,351,645...96,356,761
Ensembl chr 9:124,865,211...124,870,458
JBrowse link
G HTRA1 HtrA serine peptidase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3034116|PMID:14973287) MGI
Ensembl
PMID:14973287 GO_REF:0000107 MGI:3034116 NCBI chr10:119,030,409...119,083,682
Ensembl chr10:122,441,098...122,494,733
JBrowse link
G HTRA3 HtrA serine peptidase 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 4:8,335,529...8,374,510 JBrowse link
G IL17RD interleukin 17 receptor D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:57,023,622...57,098,869
Ensembl chr 3:58,240,835...58,309,409
JBrowse link
G LDLRAD4 low density lipoprotein receptor class A domain containing 4 involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr18:669,862...1,110,558
Ensembl chr18:2,845,198...2,879,363
JBrowse link
G LEMD3 LEM domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,668,368...23,747,369
Ensembl chr12:24,172,749...24,252,314
JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) BHF-UCL PMID:31023188 MGI:6434720 NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979
JBrowse link
G MECOM MDS1 and EVI1 complex locus NOT|involved_in ISO (PMID:15897867) UniProt PMID:15897867 NCBI chr 3:166,099,530...166,677,739
Ensembl chr 3:174,154,814...174,731,252
JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in ISO (PMID:19293183) UniProt PMID:19293183 NCBI chr14:17,224,870...17,273,252
Ensembl chr14:35,404,127...35,626,722
JBrowse link
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3588024|PMID:16103213) MGI
Ensembl
PMID:16103213 GO_REF:0000107 MGI:3588024 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062
JBrowse link
G ONECUT2 one cut homeobox 2 acts_upstream_of_or_within ISO (MGI:3588024|PMID:16103213) MGI PMID:16103213 MGI:3588024 NCBI chr18:50,826,110...50,882,127 JBrowse link
G PBLD phenazine biosynthesis like protein domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,766,873...64,817,055
Ensembl chr10:67,077,445...67,126,980
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:17327236) UniProt PMID:17327236 NCBI chr16:1,394,447...1,463,735 JBrowse link
G PEG10 paternally expressed 10 involved_in ISO (PMID:15611116) HGNC-UCL PMID:15611116 NCBI chr 7:86,606,249...86,619,580 JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:9,389,829...9,404,099
Ensembl chr19:10,053,254...10,066,853
JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr20:53,989,384...54,052,151
Ensembl chr20:55,267,089...55,329,347
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:31611175) ARUK-UCL
Ensembl
PMID:31611175 GO_REF:0000107 Ensembl chr22:45,218,364...45,302,970 JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of_or_within
involved_in
ISO (PMID:28467929)
(PMID:31023188)
ARUK-UCL
BHF-UCL
PMID:28467929 PMID:31023188 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:40,853,227...40,906,044
Ensembl chr14:59,117,020...59,162,928
JBrowse link
G PRDM16 PR/SET domain 16 NOT|involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:14656887)
(MGI:4430027|PMID:20007998)
UniProt
Ensembl
MGI
PMID:14656887 PMID:20007998 GO_REF:0000107 MGI:4430027 NCBI chr 1:1,730,122...2,100,636
Ensembl chr 1:2,981,667...3,234,251
JBrowse link
G RASL11B RAS like family 11 member B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3505646|PMID:15239668) MGI
Ensembl
PMID:15239668 GO_REF:0000107 MGI:3505646 NCBI chr 4:71,101,709...71,106,235
Ensembl chr 4:77,655,461...77,659,972
JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G SKI SKI proto-oncogene acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5300220|PMID:21937600)
(PMID:15312649)
MGI
Ensembl
PMID:15312649 PMID:21937600 GO_REF:0000107 MGI:5300220 NCBI chr 1:944,428...1,029,695
Ensembl chr 1:2,091,620...2,174,080
JBrowse link
G SKIL SKI like proto-oncogene acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3530729|PMID:15677329) MGI
Ensembl
InterPro
PMID:15677329 GO_REF:0000002 GO_REF:0000107 MGI:3530729 NCBI chr 3:167,372,104...167,411,287
Ensembl chr 3:175,562,007...175,600,181
JBrowse link
G SKOR2 SKI family transcriptional corepressor 2 involved_in
NOT|acts_upstream_of_or_within
ISO (PMID:16200078)
(MGI:5300220|PMID:21937600)
UniProt
MGI
PMID:16200078 PMID:21937600 MGI:5300220 NCBI chr18:40,594,124...40,639,720 JBrowse link
G SLC2A10 solute carrier family 2 member 10 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16550171), (PMID:26376865) ARUK-UCL
Ensembl
PMID:16550171 PMID:26376865 GO_REF:0000107 NCBI chr20:43,043,801...43,068,304
Ensembl chr20:44,128,837...44,153,148
JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,648,709...45,728,821
Ensembl chr15:63,923,379...64,001,154
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:12151385), (PMID:17438144), (PMID:18762808), (PMID:9256479) BHF-UCL PMID:9256479 PMID:12151385 PMID:17438144 PMID:18762808 NCBI chr18:42,306,324...42,337,214 JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:90,995,923...91,112,240
Ensembl chr 7:104,500,965...104,568,046
JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:58,638,995...58,759,443
Ensembl chr17:63,731,386...63,809,298
JBrowse link
G SNX1 sorting nexin 1 acts_upstream_of_or_within ISO (MGI:3505646|PMID:15239668) MGI PMID:15239668 MGI:3505646 NCBI chr15:43,048,974...43,096,544
Ensembl chr15:61,340,352...61,382,700
JBrowse link
G SNX25 sorting nexin 25 involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:177,377,302...177,529,601
Ensembl chr 4:189,631,239...189,746,590
JBrowse link
G SNX6 sorting nexin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:15,319,526...15,388,326
Ensembl chr14:33,511,019...33,576,705
JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,182,976...17,286,566
Ensembl chr15:35,439,762...35,536,565
JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr2A:65,380,608...65,503,139
Ensembl chr2A:66,503,260...66,624,840
JBrowse link
G SPRED3 sprouty related EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr19:35,482,436...35,490,745
Ensembl chr19:44,054,053...44,061,962
JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:115,570,788...115,578,824
Ensembl chr 4:126,718,811...126,719,770
JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408
JBrowse link
G STRAP serine/threonine kinase receptor associated protein involved_in
acts_upstream_of_or_within
ISO (PMID:23687415)
(MGI:1321347|PMID:9856985)
UniProt
MGI
PMID:9856985 PMID:23687415 MGI:1321347 NCBI chr12:15,883,512...15,904,778
Ensembl chr12:16,279,956...16,300,746
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:694,414...696,682 JBrowse link
G TDGF1 teratocarcinoma-derived growth factor 1 acts_upstream_of_or_within ISO (MGI:3771280|PMID:17991893) MGI PMID:17991893 MGI:3771280 NCBI chr 3:46,473,282...46,478,454
Ensembl chr 3:47,577,949...47,583,126
JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,487,561...23,493,452
Ensembl chr16:31,842,437...31,848,327
JBrowse link
G TGFB3 transforming growth factor beta 3 ISO RGD PMID:12071374 RGD:730235 NCBI chr14:56,516,697...56,542,097
Ensembl chr14:75,359,505...75,382,412
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO RGD PMID:10746731 RGD:1579946 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587
JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3528807|PMID:15657445) MGI
Ensembl
PMID:15657445 GO_REF:0000107 MGI:3528807 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G VASN vasorin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:3,298,836...3,310,548
Ensembl chr16:4,475,506...4,477,527
JBrowse link
G VEPH1 ventricular zone expressed PH domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:154,308,573...154,552,029
Ensembl chr 3:162,357,876...162,604,358
JBrowse link
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 involved_in ISO (PMID:21054789) UniProt PMID:21054789
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:44,924,892...44,932,578
Ensembl chr17:49,797,334...49,805,569
JBrowse link
G WNT1 Wnt family member 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3628833|PMID:16601693) MGI
Ensembl
PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A involved_in ISO (PMID:25514493) UniProt PMID:25514493 NCBI chr19:3,066,554...3,090,285 JBrowse link
G ZNF451 zinc finger protein 451 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:56,647,589...56,728,231
Ensembl chr 6:58,279,387...58,358,935
JBrowse link
positive regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in ISO (MGI:3829110|PMID:18625725) BHF-UCL PMID:18625725 MGI:3829110 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054
JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3628833|PMID:16601693) MGI
Ensembl
PMID:16601693 GO_REF:0000107 MGI:3628833 Ensembl chr16:278,239...337,891 JBrowse link
G C20H20orf27 chromosome 20 C20orf27 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,836,066...3,850,936
Ensembl chr20:3,593,404...3,608,267
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in ISO (PMID:16943770) BHF-UCL PMID:16943770 NCBI chr11:2,908,537...2,911,134 JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:21,838,902...21,845,355
Ensembl chr 9:22,455,662...22,462,156
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in ISO (MGI:3690196|PMID:16619037) UniProt PMID:16619037 MGI:3690196 NCBI chr 6:137,134,142...137,136,550 JBrowse link
G CREBBP CREB binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:2,645,445...2,800,975
Ensembl chr16:3,820,519...3,974,206
JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443
JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604
JBrowse link
G FERMT1 FERM domain containing kindlin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,063,480...6,120,206
Ensembl chr20:5,856,287...5,902,251
JBrowse link
G FLCN folliculin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5050037|PMID:21258407) MGI
Ensembl
PMID:21258407 GO_REF:0000107 MGI:5050037 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme ISO RGD PMID:15194465 RGD:1582619 NCBI chr15:69,560,774...69,576,007
Ensembl chr15:88,763,269...88,774,023
JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:14,041,192...14,059,402
Ensembl chr19:14,885,185...14,889,701
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:26880260 RGD:13504840 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:14678985) UniProt PMID:14678985 NCBI chr 7:131,506,711...131,722,943 JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872
JBrowse link
G ING2 inhibitor of growth family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:175,683,040...175,689,646
Ensembl chr 4:187,909,495...187,915,674
JBrowse link
G ITGA8 integrin subunit alpha 8 acts_upstream_of_or_within ISO (MGI:3714574|PMID:17537792) MGI PMID:17537792 MGI:3714574 NCBI chr10:15,838,320...16,045,206
Ensembl chr10:16,114,999...16,321,360
JBrowse link
G LRG1 leucine rich alpha-2-glycoprotein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5543310|PMID:23868260) MGI
Ensembl
PMID:23868260 GO_REF:0000107 MGI:5543310 NCBI chr19:3,557,079...3,560,193
Ensembl chr19:4,504,704...4,507,790
JBrowse link
G MEN1 menin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164
JBrowse link
G MYOCD myocardin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659
JBrowse link
G NPNT nephronectin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3714574|PMID:17537792) MGI
Ensembl
PMID:17537792 GO_REF:0000107 MGI:3714574 NCBI chr 4:98,365,727...98,445,746
Ensembl chr 4:108,974,971...109,054,671
JBrowse link
G RNF111 ring finger protein 111 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3628833|PMID:16601693) MGI
Ensembl
PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr15:37,957,390...38,068,006
Ensembl chr15:56,265,379...56,374,484
JBrowse link
G SDCBP syndecan binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,992,627...55,022,560
Ensembl chr 8:56,643,962...56,673,833
JBrowse link
G SLC2A10 solute carrier family 2 member 10 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:26376865) ARUK-UCL
Ensembl
PMID:26376865 GO_REF:0000107 NCBI chr20:43,043,801...43,068,304
Ensembl chr20:44,128,837...44,153,148
JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359
JBrowse link
G SNW1 SNW domain containing 1 involved_in ISO (PMID:11278756) UniProt PMID:11278756 NCBI chr14:58,271,830...58,315,773
Ensembl chr14:77,472,387...77,517,315
JBrowse link
G STK11 serine/threonine kinase 11 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr19:1,188,537...1,210,677 JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,487,561...23,493,452
Ensembl chr16:31,842,437...31,848,327
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 acts_upstream_of_or_within ISO (MGI:5617089|PMID:25382630) RGD
MGI
PMID:8106553 PMID:25382630 MGI:5617089 RGD:1579949 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587
JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170
JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:15,325,094...15,460,908
Ensembl chr2B:148,460,904...148,596,500
JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBN1 fibrillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111
JBrowse link
G FBN2 fibrillin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:123,673,209...123,953,741
Ensembl chr 5:129,435,248...129,715,711
JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:32,956,937...33,409,286
Ensembl chr2A:33,667,191...34,120,602
JBrowse link
G NRROS negative regulator of reactive oxygen species involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:193,984,797...194,007,173
Ensembl chr 3:203,920,334...203,948,506
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15229
    cellular process 14344
      regulation of cellular process 9752
        regulation of cellular response to growth factor stimulus 293
          regulation of cellular response to transforming growth factor beta stimulus 127
            regulation of transforming growth factor beta receptor signaling pathway 124
              negative regulation of transforming growth factor beta receptor signaling pathway + 76
              positive regulation of transforming growth factor beta receptor signaling pathway 32
              regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 0
              regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry 0
Path 2
Term Annotations click to browse term
  biological_process 15229
    biological regulation 10799
      regulation of biological process 10214
        regulation of cellular process 9752
          signal transduction 4990
            cell surface receptor signaling pathway 2369
              enzyme linked receptor protein signaling pathway 866
                transmembrane receptor protein serine/threonine kinase signaling pathway 352
                  regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 242
                    regulation of transforming growth factor beta receptor signaling pathway 124
                      negative regulation of transforming growth factor beta receptor signaling pathway + 76
                      positive regulation of transforming growth factor beta receptor signaling pathway 32
                      regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 0
                      regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry 0
paths to the root