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ONTOLOGY REPORT - ANNOTATIONS

Term:endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
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Accession:GO:0016894 term browser browse the term
Definition:Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters.
Comment:Note that this activity can catalyze cleavage of DNA or RNA.
Synonyms:exact_synonym: 3'-endonuclease activity
 related_synonym: endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
 xref: EC:3.1.31.1


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endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SND1 staphylococcal nuclease and tudor domain containing 1 enables IEA UniProt GO_REF:0000003 NCBI chr 7:119,647,536...120,084,110
Ensembl chr 7:132,302,235...132,738,223 		JBrowse link
3'-flap endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MUS81 MUS81 structure-specific endonuclease subunit enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:61,220,699...61,226,747
Ensembl chr11:64,549,840...64,555,875 		JBrowse link
crossover junction DNA endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EME1 essential meiotic structure-specific endonuclease 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr17:44,467,537...44,475,883
Ensembl chr17:49,341,791...49,349,959 		JBrowse link
G EME2 essential meiotic structure-specific endonuclease subunit 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:395,571...403,233
Ensembl chr16:1,825,622...1,829,557 		JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease enables IEA Ensembl GO_REF:0000107 NCBI chr2A:17,735,953...17,766,018
Ensembl chr2A:17,862,070...17,892,048 		JBrowse link
G MUS81 MUS81 structure-specific endonuclease subunit enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr11:61,220,699...61,226,747
Ensembl chr11:64,549,840...64,555,875 		JBrowse link
G RAD51C RAD51 paralog C contributes_to
enables		 ISO
IEA		 (PMID:14716019) UniProtKB
TreeGrafter
Ensembl		 PMID:14716019 GO_REF:0000107 GO_REF:0000118 NCBI chr17:52,769,446...52,808,467
Ensembl chr17:57,621,552...57,660,701 		JBrowse link
G SLX1A SLX1 homolog A, structure-specific endonuclease subunit enables IEA UniProt
TreeGrafter		 GO_REF:0000104 GO_REF:0000118
G TEFM transcription elongation factor, mitochondrial NOT|enables ISO (PMID:21278163) UniProt PMID:21278163 NCBI chr17:25,933,934...25,941,220
Ensembl chr17:25,423,956...25,432,198 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 contributes_to
enables		 ISO
IEA		 (PMID:14716019), (PMID:23108668) UniProtKB
Ensembl		 PMID:14716019 PMID:23108668 GO_REF:0000107 NCBI chr14:84,323,644...84,341,763
Ensembl chr14:104,131,903...104,149,037 		JBrowse link
deoxyribonuclease II activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNASE2 deoxyribonuclease 2, lysosomal enables IEA InterPro
TreeGrafter
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr19:12,436,898...12,443,530
Ensembl chr19:13,180,073...13,185,650 		JBrowse link
G DNASE2B deoxyribonuclease 2 beta enables ISO
IEA		 RGD
UniProt
TreeGrafter
InterPro		 PMID:10558878 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000118 RGD:70721 NCBI chr 1:116,946,513...116,963,483
Ensembl chr 1:85,807,300...85,824,257 		JBrowse link
ribonuclease A activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNASE8 ribonuclease A family member 8 enables IEA Ensembl GO_REF:0000107 NCBI chr14:1,872,595...1,873,331
Ensembl chr14:19,954,680...19,955,147 		JBrowse link
RNA endonuclease activity, producing 3'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RIDA reactive intermediate imine deaminase A homolog ISO RGD PMID:10400702 RGD:9685547 NCBI chr 8:94,739,120...94,753,934
Ensembl chr 8:96,923,776...96,938,512 		JBrowse link
tRNA-intron endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TSEN2 tRNA splicing endonuclease subunit 2 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000118 NCBI chr 3:12,410,885...12,463,932
Ensembl chr 3:12,759,375...12,800,201 		JBrowse link
G TSEN34 tRNA splicing endonuclease subunit 34 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000118 NCBI chr19:51,121,560...51,125,768
Ensembl chr19:59,964,174...59,968,453 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17492
    catalytic activity 5384
      hydrolase activity 2314
        hydrolase activity, acting on ester bonds 742
          nuclease activity 199
            endonuclease activity 113
              endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 15
                DNA endonuclease activity, producing 3'-phosphomonoesters + 10
                RNA endonuclease activity, producing 3'-phosphomonoesters + 4
paths to the root