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ONTOLOGY REPORT - ANNOTATIONS


Term:endodeoxyribonuclease activity, producing 5'-phosphomonoesters
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Accession:GO:0016888 term browser browse the term
Definition:Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
Synonyms:xref: EC:3.1.21;   reactome:R-HSA-912368 "SPO11 hydrolyzes DNA forming double-strand breaks"


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endodeoxyribonuclease activity, producing 5'-phosphomonoesters term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Endov endonuclease V JBrowse link 10 108,630,723 108,646,679 RGD:1624291
G LOC103690794 nascent polypeptide-associated complex subunit alpha, muscle-specific form-like JBrowse link X 5,881,524 5,887,879 RGD:1600115
G Tatdn1 TatD DNase domain containing 1 JBrowse link 7 98,782,164 98,813,001 RGD:1600115
G Tatdn2 TatD DNase domain containing 2 JBrowse link 4 145,653,299 145,669,343 RGD:1600115
5'-flap endonuclease activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dna2 DNA replication helicase/nuclease 2 RGD:1600115
RGD:13792537
G Exo1 exonuclease 1 JBrowse link 13 93,936,989 93,962,749 RGD:13792537
G Fan1 FANCD2 and FANCI associated nuclease 1 JBrowse link 1 125,182,117 125,209,772 RGD:1624291
RGD:13792537
G Fen1 flap structure-specific endonuclease 1 JBrowse link 1 226,251,516 226,256,160 RGD:1624291
RGD:13792537
G Gen1 GEN1 Holliday junction 5' flap endonuclease JBrowse link 6 36,910,064 36,940,868 RGD:1624291
RGD:13792537
G Slc25a16 solute carrier family 25 member 16 JBrowse link 20 27,283,383 27,308,069 RGD:1600115
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1624291
RGD:13792537
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:1624291
RGD:13792537
deoxyribonuclease I activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:13792537
G Dnase1 deoxyribonuclease 1 JBrowse link 10 11,757,681 11,760,672 RGD:1298888
RGD:13792537
RGD:1624291
G Dnase1l1 deoxyribonuclease 1-like 1 JBrowse link X 156,429,521 156,438,066 RGD:13792537
G Dnase1l2 deoxyribonuclease 1 like 2 JBrowse link 10 13,812,335 13,814,514 RGD:13792537
G Dnase1l3 deoxyribonuclease 1-like 3 JBrowse link 15 18,710,492 18,736,476 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19619
    catalytic activity 6006
      catalytic activity, acting on DNA 203
        deoxyribonuclease activity 63
          endodeoxyribonuclease activity 44
            endodeoxyribonuclease activity, producing 5'-phosphomonoesters 17
              5'-flap endonuclease activity 8
              CC-preferring endodeoxyribonuclease activity 0
              class II DNA-(apurinic or apyrimidinic site) endonuclease activity 0
              deoxyribonuclease I activity 5
              deoxyribonuclease IV (phage-T4-induced) activity 0
              deoxyribonuclease V activity 0
              type I site-specific deoxyribonuclease activity 0
              type II site-specific deoxyribonuclease activity 0
              type III site-specific deoxyribonuclease activity 0
Path 2
Term Annotations click to browse term
  molecular_function 19619
    catalytic activity 6006
      hydrolase activity 2595
        hydrolase activity, acting on ester bonds 782
          nuclease activity 212
            endonuclease activity 121
              endodeoxyribonuclease activity 44
                endodeoxyribonuclease activity, producing 5'-phosphomonoesters 17
                  5'-flap endonuclease activity 8
                  CC-preferring endodeoxyribonuclease activity 0
                  class II DNA-(apurinic or apyrimidinic site) endonuclease activity 0
                  deoxyribonuclease I activity 5
                  deoxyribonuclease IV (phage-T4-induced) activity 0
                  deoxyribonuclease V activity 0
                  type I site-specific deoxyribonuclease activity 0
                  type II site-specific deoxyribonuclease activity 0
                  type III site-specific deoxyribonuclease activity 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.