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ONTOLOGY REPORT - ANNOTATIONS

Term:ligase activity, forming phosphoric ester bonds
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Accession:GO:0016886 term browser browse the term
Definition:Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
Synonyms:xref: EC:6.5


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DNA ligase (ATP) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lig1 DNA ligase 1 enables IEA
IBA		 GO_REF:0000003
GO_REF:0000002
GO_REF:0000033		 UniProt
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413 		JBrowse link
G Lig3 DNA ligase 3 enables ISO
IBA		 (PMID:10207110)
GO_REF:0000033
(PMID:7565692)		 RGD
GO_Central		 PMID:7565692 PMID:10207110 GO_REF:0000033 NCBI chr10:67,717,808...67,741,141
Ensembl chr10:67,717,812...67,798,414 		JBrowse link
G Lig4 DNA ligase 4 enables IDA
ISO
IBA		 (PMID:15194694)
GO_REF:0000033
(PMID:22192310), (PMID:23523427), (PMID:29980672), (PMID:8798671)		 RGD
GO_Central		 PMID:8798671 PMID:15194694 PMID:22192310 PMID:23523427 PMID:29980672 More... GO_REF:0000033, RGD:1601271 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040 		JBrowse link
DNA ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lig1 DNA ligase 1 enables IDA
ISO		 (PMID:15871698), (PMID:9809069) RGD PMID:9809069 PMID:15871698 PMID:1730240 RGD:724410 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413 		JBrowse link
G Lig3 DNA ligase 3 enables IDA
ISO		 (PMID:24674627)
(PMID:9809069)		 RGD PMID:9809069 PMID:24674627 PMID:17412650 RGD:2302580 NCBI chr10:67,717,808...67,741,141
Ensembl chr10:67,717,812...67,798,414 		JBrowse link
G Lig4 DNA ligase 4 enables ISO (PMID:12517771), (PMID:17290226) RGD PMID:12517771 PMID:17290226 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040 		JBrowse link
peptide lactyltransferase (ATP-dependent) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 enables ISS
ISO		 GO_REF:0000024
(PMID:38512451), (PMID:38653238)		 UniProt
RGD		 PMID:38512451 PMID:38653238 GO_REF:0000024 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147 		JBrowse link
RNA ligase (ATP) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rlig1 RNA 5'-phosphate and 3'-OH ligase 1 enables ISO
IEA		 (PMID:36792600)
GO_REF:0000002
GO_REF:0000107		 RGD
InterPro
Ensembl		 PMID:36792600 GO_REF:0000002 GO_REF:0000107 NCBI chr 7:35,396,876...35,408,633
Ensembl chr 7:35,397,995...35,409,600 		JBrowse link
G Rtcb RNA 2',3'-cyclic phosphate and 5'-OH ligase enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:17,907,668...17,927,136
Ensembl chr 7:17,907,705...17,927,132 		JBrowse link
RNA ligase (GTP) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtcb RNA 2',3'-cyclic phosphate and 5'-OH ligase enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000002
(PMID:21311021), (PMID:24870230)		 UniProt
InterPro
RGD		 PMID:21311021 PMID:24870230 GO_REF:0000002 GO_REF:0000024 NCBI chr 7:17,907,668...17,927,136
Ensembl chr 7:17,907,705...17,927,132 		JBrowse link
RNA-3'-phosphate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtca RNA 3'-terminal phosphate cyclase enables ISO
IBA		 (PMID:9184239)
GO_REF:0000033		 RGD
GO_Central		 PMID:9184239 GO_REF:0000033 NCBI chr 2:204,455,175...204,476,450
Ensembl chr 2:204,455,175...204,476,460 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20736
    catalytic activity 6109
      ligase activity 179
        ligase activity, forming phosphoric ester bonds 7
          DNA ligase activity + 3
          RNA ligase activity + 2
          RNA-3'-phosphate cyclase activity 1
          peptide lactyltransferase (ATP-dependent) activity 1
paths to the root