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ONTOLOGY REPORT - ANNOTATIONS


Term:carbon-nitrogen lyase activity
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Accession:GO:0016840 term browser browse the term
Definition:Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).
Synonyms:narrow_synonym: other carbon-nitrogen lyase activity
 xref: EC:4.3



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(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adsl adenylosuccinate lyase enables IDA
IBA
ISO
PMID:21873635
(MGI:6718249|PMID:6480832)
(PMID:27590927)
RGD PMID:6480832 PMID:27590927 PMID:3759987 PMID:21873635 PMID:21873635 MGI:6718249, RGD:5135303, RGD:13792537, RGD:13792537 NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760
JBrowse link
ammonia-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hal histidine ammonia lyase enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
argininosuccinate lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase enables IDA
IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro
RGD
PMID:8586639 PMID:21873635 PMID:4062872 GO_REF:0000002, RGD:1599287, RGD:13792537, RGD:2300098 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
D-serine ammonia-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srr serine racemase enables IEA GO_REF:0000116
GO_REF:0000003
RHEA
UniProt
GO_REF:0000003 GO_REF:0000116 NCBI chr10:59,769,563...59,786,688
Ensembl chr10:59,769,571...59,787,011
JBrowse link
formimidoyltetrahydrofolate cyclodeaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ftcd formimidoyltransferase cyclodeaminase enables TAS
ISO
IDA
(PMID:2572277)
PMID:9677387
RGD PMID:2572277 PMID:12160147 PMID:9677387 RGD:727402, RGD:10047259 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735
JBrowse link
gamma-glutamylaminecyclotransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ggact gamma-glutamylamine cyclotransferase enables ISO
ISS
(PMID:20110353)
GO_REF:0000024
RGD
UniProt
PMID:20110353 GO_REF:0000024 NCBI chr15:99,969,246...99,998,343
Ensembl chr15:99,968,282...99,993,455
JBrowse link
gamma-glutamylcyclotransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301
JBrowse link
G Ggct gamma-glutamyl cyclotransferase enables ISO
IBA
(PMID:18515354)
PMID:21873635
RGD PMID:18515354 PMID:21873635 RGD:13792537 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277
JBrowse link
glutathione specific gamma-glutamylcyclotransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 enables IEA GO_REF:0000116
GO_REF:0000003
RHEA
UniProt
GO_REF:0000003 GO_REF:0000116 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 enables IEA GO_REF:0000003
GO_REF:0000116
UniProt
RHEA
GO_REF:0000003 GO_REF:0000116 NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301
JBrowse link
histidine ammonia-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hal histidine ammonia lyase enables TAS
ISO
IBA
IDA
(MGI:52899|PMID:8486363)
PMID:21873635
(PMID:15806399)
RGD PMID:8486363 PMID:15806399 PMID:12376330 PMID:21873635 PMID:9432011 MGI:52899, RGD:628345, RGD:13792537, RGD:632935 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
L-serine ammonia-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sds serine dehydratase enables TAS
IEA
ISO
GO_REF:0000003
GO_REF:0000116
(PMID:15689518), (PMID:18342636)
UniProt
RHEA
RGD
PMID:15689518 PMID:18342636 PMID:11906824 GO_REF:0000003 GO_REF:0000116, RGD:633956 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Srr serine racemase enables ISO
IBA
(PMID:18812225)
PMID:21873635
RGD PMID:18812225 PMID:21873635 RGD:13792537 NCBI chr10:59,769,563...59,786,688
Ensembl chr10:59,769,571...59,787,011
JBrowse link
L-threonine ammonia-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sds serine dehydratase enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Sdsl serine dehydratase-like enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:36,099,693...36,109,914
Ensembl chr12:36,099,693...36,109,906
JBrowse link
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adsl adenylosuccinate lyase enables
NOT|enables
IDA
IBA
ISO
PMID:21873635
(PMID:16973378), (PMID:19405474)
(MGI:6718247|PMID:5891253)
(PMID:10888601)
RGD PMID:5891253 PMID:10888601 PMID:16973378 PMID:19405474 PMID:3689310 More... MGI:6718247, RGD:1598764, RGD:13792537, RGD:13792537, RGD:1598763 NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760
JBrowse link
peptidylamidoglycolate lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pam peptidylglycine alpha-amidating monooxygenase enables IDA
ISO
PMID:10079066
(PMID:12699694)
RGD PMID:12699694 PMID:16405966 PMID:10079066 RGD:2302419, RGD:14390048 NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965
JBrowse link
strictosidine synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apmap adipocyte plasma membrane associated protein enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:139,409,020...139,437,296
Ensembl chr 3:139,409,022...139,437,341
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20203
    catalytic activity 5865
      lyase activity 208
        carbon-nitrogen lyase activity 13
          amidine-lyase activity + 7
          amine-lyase activity + 1
          ammonia-lyase activity + 5
          cyanate hydratase activity 0
paths to the root