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ONTOLOGY REPORT - ANNOTATIONS


Term:hydro-lyase activity
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Accession:GO:0016836 term browser browse the term
Definition:Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
Synonyms:xref: EC:4.2.1;   reactome:R-HSA-9014627 "SDS dimers:PXLP dehydrate L-Thr to 2AA"


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hydro-lyase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CA1 carbonic anhydrase 1 JBrowse link 4 51,343,548 51,353,127 RGD:14298760
G CA11 carbonic anhydrase 11 JBrowse link 6 53,993,183 53,999,357 RGD:14298760
G CA12 carbonic anhydrase 12 JBrowse link 1 108,649,277 108,710,658 RGD:14298760
G CA13 carbonic anhydrase 13 JBrowse link 4 51,406,755 51,468,971 RGD:14298760
G CA14 carbonic anhydrase 14 JBrowse link 4 98,821,577 98,828,934 RGD:14298760
G CA2 carbonic anhydrase 2 JBrowse link 4 51,194,686 51,211,436 RGD:14298760
G CA4 carbonic anhydrase 4 JBrowse link 12 37,962,951 37,972,443 RGD:14298760
G CA5A carbonic anhydrase 5A JBrowse link 6 1,495,615 1,539,390 RGD:14298760
G CA5B carbonic anhydrase 5B JBrowse link X 12,295,393 12,332,283 RGD:14298760
G CA6 carbonic anhydrase 6 JBrowse link 6 69,447,662 69,468,819 RGD:14298760
G CA7 carbonic anhydrase 7 JBrowse link 6 27,548,647 27,563,966 RGD:14298760
G CA8 carbonic anhydrase 8 JBrowse link 4 73,047,867 73,172,215 RGD:14298760
G ENOSF1 enolase superfamily member 1 JBrowse link 6 105,613,211 105,642,533 RGD:14298760
G L3HYPDH trans-L-3-hydroxyproline dehydratase JBrowse link 1 188,584,363 188,616,688 RGD:14298760
G LOC100522130 fumarylacetoacetate hydrolase domain-containing protein 2 JBrowse link 3 45,857,494 45,888,353 RGD:14298760
G LOC106510546 cytochrome P450 2S1 JBrowse link 6 49,221,361 49,235,335 RGD:9068941
3-hydroxy-arachidoyl-CoA dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HACD1 3-hydroxyacyl-CoA dehydratase 1 JBrowse link 10 43,901,590 43,929,441 RGD:14298760
G HACD2 3-hydroxyacyl-CoA dehydratase 2 JBrowse link 13 136,834,103 136,933,564 RGD:14298760
G HACD3 3-hydroxyacyl-CoA dehydratase 3 JBrowse link 1 163,525,872 163,567,649 RGD:14298760
G HACD4 3-hydroxyacyl-CoA dehydratase 4 JBrowse link 1 201,885,874 201,910,667 RGD:14298760
3-hydroxy-behenoyl-CoA dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HACD1 3-hydroxyacyl-CoA dehydratase 1 JBrowse link 10 43,901,590 43,929,441 RGD:14298760
G HACD2 3-hydroxyacyl-CoA dehydratase 2 JBrowse link 13 136,834,103 136,933,564 RGD:14298760
G HACD3 3-hydroxyacyl-CoA dehydratase 3 JBrowse link 1 163,525,872 163,567,649 RGD:14298760
G HACD4 3-hydroxyacyl-CoA dehydratase 4 JBrowse link 1 201,885,874 201,910,667 RGD:14298760
3-hydroxy-lignoceroyl-CoA dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HACD1 3-hydroxyacyl-CoA dehydratase 1 JBrowse link 10 43,901,590 43,929,441 RGD:14298760
G HACD2 3-hydroxyacyl-CoA dehydratase 2 JBrowse link 13 136,834,103 136,933,564 RGD:14298760
G HACD3 3-hydroxyacyl-CoA dehydratase 3 JBrowse link 1 163,525,872 163,567,649 RGD:14298760
G HACD4 3-hydroxyacyl-CoA dehydratase 4 JBrowse link 1 201,885,874 201,910,667 RGD:14298760
3-hydroxyacyl-CoA dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HACD1 3-hydroxyacyl-CoA dehydratase 1 JBrowse link 10 43,901,590 43,929,441 RGD:14298760
G HACD2 3-hydroxyacyl-CoA dehydratase 2 JBrowse link 13 136,834,103 136,933,564 RGD:14298760
G HACD3 3-hydroxyacyl-CoA dehydratase 3 JBrowse link 1 163,525,872 163,567,649 RGD:14298760
G HACD4 3-hydroxyacyl-CoA dehydratase 4 JBrowse link 1 201,885,874 201,910,667 RGD:14298760
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 JBrowse link 2 123,313,445 123,401,386 RGD:9068941
4-alpha-hydroxytetrahydrobiopterin dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PCBD1 pterin-4 alpha-carbinolamine dehydratase 1 JBrowse link 14 73,769,339 73,807,278 RGD:14298760
G PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 JBrowse link 2 137,082,920 137,135,175 RGD:14298760
aconitate hydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACO1 aconitase 1 JBrowse link 10 33,937,833 34,001,895 RGD:14298760
G ACO2 aconitase 2 JBrowse link 5 7,014,383 7,071,023 RGD:14298760
G IREB2 iron responsive element binding protein 2 JBrowse link 7 47,481,539 47,529,199 RGD:14298760
ADP-dependent NAD(P)H-hydrate dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NAXD NAD(P)HX dehydratase JBrowse link 11 77,210,164 77,230,687 RGD:14298760
ATP-dependent NAD(P)H-hydrate dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NAXD NAD(P)HX dehydratase JBrowse link 11 77,210,164 77,230,687 RGD:14298760
carbonate dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CA1 carbonic anhydrase 1 JBrowse link 4 51,343,548 51,353,127 RGD:14298760
G CA10 carbonic anhydrase 10 JBrowse link 12 27,979,321 28,619,022 RGD:14298760
G CA11 carbonic anhydrase 11 JBrowse link 6 53,993,183 53,999,357 RGD:14298760
G CA12 carbonic anhydrase 12 JBrowse link 1 108,649,277 108,710,658 RGD:14298760
G CA13 carbonic anhydrase 13 JBrowse link 4 51,406,755 51,468,971 RGD:14298760
G CA14 carbonic anhydrase 14 JBrowse link 4 98,821,577 98,828,934 RGD:14298760
G CA2 carbonic anhydrase 2 JBrowse link 4 51,194,686 51,211,436 RGD:14298760
G CA3 carbonic anhydrase 3 JBrowse link 4 51,227,485 51,237,861 RGD:14298760
G CA4 carbonic anhydrase 4 JBrowse link 12 37,962,951 37,972,443 RGD:14298760
G CA5A carbonic anhydrase 5A JBrowse link 6 1,495,615 1,539,390 RGD:14298760
G CA5B carbonic anhydrase 5B JBrowse link X 12,295,393 12,332,283 RGD:14298760
G CA6 carbonic anhydrase 6 JBrowse link 6 69,447,662 69,468,819 RGD:14298760
G CA7 carbonic anhydrase 7 JBrowse link 6 27,548,647 27,563,966 RGD:14298760
G CA8 carbonic anhydrase 8 JBrowse link 4 73,047,867 73,172,215 RGD:14298760
G CA9 carbonic anhydrase 9 JBrowse link 1 236,393,727 236,400,994 RGD:14298760
citrate dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACO2 aconitase 2 JBrowse link 5 7,014,383 7,071,023 RGD:14298760
crotonyl-CoA hydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDYL chromodomain Y like JBrowse link 7 2,845,903 2,967,537 RGD:9068941
cystathionine beta-synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CBS cystathionine beta-synthase JBrowse link 13 206,205,942 206,231,363 RGD:14298760
D-glutamate cyclase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DGLUCY D-glutamate cyclase JBrowse link 7 112,753,719 112,862,247 RGD:9068941
dTDP-glucose 4,6-dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TGDS TDP-glucose 4,6-dehydratase JBrowse link 11 63,695,612 63,716,614 RGD:14298760
enoyl-CoA hydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AUH AU RNA binding methylglutaconyl-CoA hydratase JBrowse link 14 2,398,456 2,546,329 RGD:14298760
G E4F1 E4F transcription factor 1 JBrowse link 3 39,757,679 39,773,024 RGD:14298760
G ECHDC1 ethylmalonyl-CoA decarboxylase 1 JBrowse link 1 35,852,939 35,909,314 RGD:14298760
G ECHDC2 enoyl-CoA hydratase domain containing 2 JBrowse link 6 159,326,146 159,347,178 RGD:14298760
G ECHDC3 enoyl-CoA hydratase domain containing 3 JBrowse link 10 60,117,425 60,138,662 RGD:9068941
G ECHS1 enoyl-CoA hydratase, short chain 1 JBrowse link 14 141,340,320 141,348,870 RGD:14298760
G EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase JBrowse link 13 123,104,085 123,162,119 RGD:14298760
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha JBrowse link 3 112,753,343 112,797,627 RGD:14298760
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 JBrowse link 2 123,313,445 123,401,386 RGD:14298760
G RNPS1 RNA binding protein with serine rich domain 1 JBrowse link 3 39,739,058 39,749,600 RGD:14298760
fumarate hydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FH fumarate hydratase JBrowse link 10 12,404,143 12,431,843 RGD:14298760
GDP-mannose 4,6-dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GMDS GDP-mannose 4,6-dehydratase JBrowse link 7 849,088 1,285,563 RGD:14298760
glyoxalase (glycolic acid-forming) activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:14298760
L-fuconate dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENOSF1 enolase superfamily member 1 JBrowse link 6 105,613,211 105,642,533 RGD:14298760
long-chain-enoyl-CoA hydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha JBrowse link 3 112,753,343 112,797,627 RGD:9068941
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 JBrowse link 2 123,313,445 123,401,386 RGD:14298760
methylthioribulose 1-phosphate dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APIP APAF1 interacting protein JBrowse link 2 26,095,020 26,115,462 RGD:14298760
phosphopyruvate hydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENO1 enolase 1 JBrowse link 6 69,385,879 69,401,664 RGD:14298760
G ENO2 enolase 2 JBrowse link 5 63,799,927 63,809,067 RGD:14298760
G ENO3 enolase 3 JBrowse link 12 51,954,614 51,959,991 RGD:14298760
G ENO4 enolase 4 JBrowse link 14 127,032,217 127,063,660 RGD:14298760
porphobilinogen synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALAD aminolevulinate dehydratase JBrowse link 1 254,015,426 254,027,584 RGD:14298760
protein deglycase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:14298760
RGD:9068941
urocanate hydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G UROC1 urocanate hydratase 1 JBrowse link 7 53,592,763 53,634,214 RGD:14298760
uroporphyrinogen-III synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HMBS hydroxymethylbilane synthase JBrowse link 9 46,300,039 46,308,681 RGD:9068941
G UROS uroporphyrinogen III synthase JBrowse link 14 135,101,609 135,131,082 RGD:14298760
RGD:9068941
very-long-chain 3-hydroxyacyl-CoA dehydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HACD1 3-hydroxyacyl-CoA dehydratase 1 JBrowse link 10 43,901,590 43,929,441 RGD:14298760
G HACD2 3-hydroxyacyl-CoA dehydratase 2 JBrowse link 13 136,834,103 136,933,564 RGD:14298760
G HACD3 3-hydroxyacyl-CoA dehydratase 3 JBrowse link 1 163,525,872 163,567,649 RGD:14298760
G HACD4 3-hydroxyacyl-CoA dehydratase 4 JBrowse link 1 201,885,874 201,910,667 RGD:14298760

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Term Annotations click to browse term
  molecular_function 17331
    catalytic activity 5430
      lyase activity 176
        carbon-oxygen lyase activity 70
          hydro-lyase activity 55
            (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity 0
            (R)-2-methylmalate dehydratase activity 0
            (S)-2-methylmalate dehydratase activity 0
            (S)-norcoclaurine synthase activity 0
            1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity 0
            1,5-anhydro-D-fructose dehydratase activity 0
            14betaH-scalarane-17alpha-19-diol synthase activity 0
            16-alpha-hydroxyprogesterone dehydratase activity 0
            17(E)-cheilanthenediol synthase activity 0
            2,4,4-trimethylpent-2-enoyl-CoA hydratase activity 0
            2,5,7-trihydroxyflavanone 6C-glucoside dehydratase activity 0
            2-dehydro-3-deoxy-L-arabinonate dehydratase activity 0
            2-hydroxydec-2,4-diene-1,10-dioate hydratase activity 0
            2-hydroxyeriodictyol 6C-glucoside dehydratase activity 0
            2-hydroxyglutaryl-CoA dehydratase activity 0
            2-hydroxyhexa-2,4-dienoate hydratase activity 0
            2-hydroxyisobutyrate dehydratase activity 0
            2-hydroxyisoflavanone dehydratase activity 0
            2-hydroxynaringenin-6C-glucoside dehydratase activity 0
            2-keto-3-deoxygalactonate aldolase activity 0
            2-methylcitrate dehydratase activity 0
            2-methylhex-2-enoyl-CoA hydratase activity 0
            2-methylisocitrate dehydratase activity 0
            2-oxo-hept-3-ene-1,7-dioate hydratase activity 0
            2-oxopent-4-enoate hydratase activity 0
            3-cyanoalanine hydratase activity 0
            3-dehydroquinate dehydratase activity 0
            3-dehydroshikimate dehydratase activity 0
            3-hydroxy-arachidoyl-CoA dehydratase activity 4
            3-hydroxy-behenoyl-CoA dehydratase activity 4
            3-hydroxy-cerotoyl-CoA dehydratase activity 0
            3-hydroxy-lignoceroyl-CoA dehydratase activity 4
            3-hydroxyacyl-CoA dehydratase activity 5
            3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity + 0
            3-hydroxybutyryl-CoA dehydratase activity 0
            3-hydroxypropionyl-CoA dehydratase activity 0
            3-isopropylmalate dehydratase activity 0
            3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity 0
            3R-hydroxyacyl-CoA dehydratase activity 0
            3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity 0
            4-alpha-hydroxytetrahydrobiopterin dehydratase activity 2
            4-hydroxy-tetrahydrodipicolinate synthase activity 0
            4-hydroxybutanoyl-CoA dehydratase activity 0
            4-methyloct-2-enoyl-CoA hydratase activity 0
            4-oxalmesaconate hydratase activity 0
            5-alpha-hydroxysteroid dehydratase activity 0
            5-chloro-2-oxopent-4-enoate hydratase activity 0
            5-dehydro-4-deoxyglucarate dehydratase activity 0
            6-carboxy-5,6,7,8-tetrahydropterin synthase activity 0
            ADP-dependent NAD(P)H-hydrate dehydratase activity 1
            ATP-dependent NAD(P)H-hydrate dehydratase activity 1
            CDP-glucose 4,6-dehydratase activity 0
            D(-)-tartrate dehydratase activity 0
            D-fuconate dehydratase activity 0
            D-glutamate cyclase activity 1
            E-phenylitaconyl-CoA hydratase activity 0
            GDP-mannose 4,6-dehydratase activity 1
            L(+)-tartrate dehydratase activity 0
            L-altrarate dehydratase activity 0
            L-arabinonate dehydratase activity 0
            L-erythro-3-methylmalyl-CoA dehydratase activity 0
            L-fuconate dehydratase activity 1
            L-rhamnonate dehydratase activity 0
            L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity 0
            O-succinylbenzoate synthase activity 0
            OPC4-trans-2-enoyl-CoA hydratase activity 0
            OPC6-trans-2-enoyl-CoA hydratase activity 0
            OPC8-trans-2-enoyl-CoA hydratase activity 0
            UDP-glucose 4,6-dehydratase activity 0
            acetylene hydratase activity 0
            acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate 0
            acetylenecarboxylate hydratase activity, producing 3-oxopropanoate 0
            aconitate hydratase activity 3
            aldos-2-ulose dehydratase activity 0
            allene oxide synthase activity 0
            altronate dehydratase activity 0
            arabinonate dehydratase activity 0
            arogenate dehydratase activity 0
            bile-acid 7alpha-dehydratase activity 0
            carbonate dehydratase activity 15
            carnitine dehydratase activity 0
            citrate dehydratase activity 1
            colneleate synthase activity 0
            colnelenate synthase activity 0
            copal-8-ol diphosphate synthase activity 0
            crotonyl-CoA hydratase activity 1
            cyanamide hydratase activity 0
            cyanide hydratase activity 0
            cyclohex-1-ene-1-carboxyl-CoA hydratase activity 0
            cyclohexa-1,5-dienecarbonyl-CoA hydratase activity 0
            cyclohexyl-isocyanide hydratase activity 0
            cystathionine beta-synthase activity 1
            dTDP-glucose 4,6-dehydratase activity 1
            dihydroxy-acid dehydratase activity 0
            dimethylmaleate hydratase activity 0
            ectoine synthase activity 0
            endosulfan diol hydrolyase (cyclizing) activity 0
            enoyl-CoA hydratase activity 10
            fumarate hydratase activity 1
            galactarate dehydratase activity 0
            galactonate dehydratase activity 0
            glucarate dehydratase activity 0
            gluconate dehydratase activity 0
            glycerol dehydratase activity 0
            glyoxalase (glycolic acid-forming) activity 1
            glyoxalase III activity 0
            homoaconitate hydratase activity 0
            hydroperoxide dehydratase activity 0
            hydroperoxy icosatetraenoate dehydratase activity 0
            imidazoleglycerol-phosphate dehydratase activity 0
            isocitrate hydro-lyase (cis-aconitate-forming) activity 0
            isohexenylglutaconyl-CoA hydratase activity 0
            itaconyl-CoA hydratase activity 0
            kievitone hydratase activity 0
            lactoyl-CoA dehydratase activity 0
            limonene 8-hydratase activity 0
            long-chain-enoyl-CoA hydratase activity 2
            lupan-3beta,20-diol synthase activity 0
            maleate hydratase activity 0
            mannonate dehydratase activity 0
            menth-2-enone hydratase activity 0
            mesaconyl-CoA hydratase activity 0
            methylglutaconyl-CoA hydratase activity 0
            methylthioribulose 1-phosphate dehydratase activity 1
            monocyclic sesterterpenediol synthase activity 0
            myo-inosose-2 dehydratase activity 0
            naphthyl-2-methylene-succinyl-CoA lyase activity 0
            nitrile hydratase activity + 0
            octopamine dehydratase activity 0
            oleate hydratase activity 0
            peregrinol diphosphate synthase activity 0
            perillyl-CoA hydratase activity 0
            phaseollidin hydratase activity 0
            phosphogluconate dehydratase activity 0
            phosphopyruvate hydratase activity 4
            porphobilinogen synthase activity 1
            prephenate dehydratase activity 0
            propanediol dehydratase activity 0
            protein deglycase activity 1
            protoaphin-aglucone dehydratase (cyclizing) activity 0
            pseudouridylate synthase activity 0
            pterin-4alpha-carbinolamine dehydratase activity 0
            pyrazolylalanine synthase activity 0
            retinol dehydratase activity 0
            scalarane-17alpha-19-diol synthase activity 0
            scytalone dehydratase activity 0
            selenocystathionine beta-synthase activity 0
            synephrine dehydratase activity 0
            tRNA threonylcarbamoyladenosine dehydratase 0
            trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity 0
            trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity 0
            trans-L-3-hydroxyproline dehydratase activity 0
            trans-feruloyl-CoA hydratase activity 0
            trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity 0
            tryptophan synthase activity 0
            urocanate hydratase activity 1
            uroporphyrinogen-III synthase activity 2
            very-long-chain 3-hydroxyacyl-CoA dehydratase activity 4
            xylonate dehydratase activity 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.