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ONTOLOGY REPORT - ANNOTATIONS


Term:lyase activity
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Accession:GO:0016829 term browser browse the term
Definition:Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
Synonyms:narrow_synonym: other lyase activity
 xref: EC:4;   Reactome:R-HSA-5696408 "PXLP-K278-PHYKPL tetramer hydrolyses 5PHL";   reactome:R-HSA-6782895 "TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe)"


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lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hacl1 2-hydroxyacyl-CoA lyase 1 enables ISO (MGI:1930887|PMID:11171065) MGI PMID:11171065 MGI:1930887 NCBI chrNW_004955430:2,055,774...2,096,260
Ensembl chrNW_004955430:2,053,640...2,096,432
JBrowse link
G Hmgb1 high mobility group box 1 enables ISO (PMID:17803946) UniProt PMID:17803946 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339
JBrowse link
G Neil1 nei like DNA glycosylase 1 enables ISO (MGI:2389521|PMID:12200441) MGI PMID:12200441 MGI:2389521 NCBI chrNW_004955450:2,883,344...2,889,593
Ensembl chrNW_004955450:2,883,560...2,887,736
JBrowse link
G Polb DNA polymerase beta enables ISO (PMID:16600869) UniProt PMID:16600869 NCBI chrNW_004955536:542,179...595,198
Ensembl chrNW_004955536:540,836...595,198
JBrowse link
G Ptges2 prostaglandin E synthase 2 enables ISO (PMID:17585783) UniProt PMID:17585783 NCBI chrNW_004955419:608,313...612,813
Ensembl chrNW_004955419:608,365...612,479
JBrowse link
(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adsl adenylosuccinate lyase enables ISO (PMID:27590927)
(MGI:6718249|PMID:6480832)
RGD
MGI
PMID:3759987 PMID:6480832 PMID:27590927 MGI:6718249 RGD:5135303 NCBI chrNW_004955413:26,067,463...26,084,669
Ensembl chrNW_004955413:26,067,516...26,088,527
JBrowse link
(S)-citramalyl-CoA lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clybl citramalyl-CoA lyase enables ISO (PMID:29056341)
(MGI:5926841|PMID:29056341)
UniProt PMID:29056341 MGI:5926841 NCBI chrNW_004955404:10,813,161...11,016,687
Ensembl chrNW_004955404:10,814,307...11,034,467
JBrowse link
1-aminocyclopropane-1-carboxylate synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Accs 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) NOT|enables ISO (PMID:11470512) UniProt PMID:11470512 NCBI chrNW_004955422:3,442,365...3,539,288 JBrowse link
17-alpha-hydroxyprogesterone aldolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102011010 steroid 17-alpha-hydroxylase/17,20 lyase enables ISO (PMID:24140098) UniProt PMID:24140098 NCBI chrNW_004955485:7,615,132...7,652,899
Ensembl chrNW_004955485:7,645,363...7,650,658
JBrowse link
2-hydroxy-3-methylhexadecanoyl-CoA lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hacl1 2-hydroxyacyl-CoA lyase 1 enables ISO (PMID:21708296) UniProt PMID:21708296 NCBI chrNW_004955430:2,055,774...2,096,260
Ensembl chrNW_004955430:2,053,640...2,096,432
JBrowse link
3-hydroxyacyl-CoA dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 enables ISO (PMID:18554506) UniProt PMID:18554506 NCBI chrNW_004955429:10,394,046...10,406,945
Ensembl chrNW_004955429:10,384,708...10,406,945
JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 enables ISO (PMID:18554506) UniProt PMID:18554506 NCBI chrNW_004955427:22,642,509...22,733,170
Ensembl chrNW_004955427:22,642,478...22,734,271
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 enables ISO (PMID:18554506) UniProt PMID:18554506 NCBI chrNW_004955450:9,923,560...9,947,519
Ensembl chrNW_004955450:9,923,560...9,942,658
JBrowse link
G Hacd4 3-hydroxyacyl-CoA dehydratase 4 enables ISO (PMID:18554506) UniProt PMID:18554506 NCBI chrNW_004955434:23,235,928...23,261,288
Ensembl chrNW_004955434:23,235,928...23,261,788
JBrowse link
G Hsd17b4 hydroxysteroid 17-beta dehydrogenase 4 ISO RGD PMID:8902630 RGD:10411904 NCBI chrNW_004955408:39,041,028...39,136,867
Ensembl chrNW_004955408:39,040,840...39,138,338
JBrowse link
3R-hydroxyacyl-CoA dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 enables ISO (PMID:18554506) Reactome PMID:18554506 NCBI chrNW_004955429:10,394,046...10,406,945
Ensembl chrNW_004955429:10,384,708...10,406,945
JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 enables ISO (PMID:18554506) Reactome PMID:18554506 NCBI chrNW_004955427:22,642,509...22,733,170
Ensembl chrNW_004955427:22,642,478...22,734,271
JBrowse link
4-alpha-hydroxytetrahydrobiopterin dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 enables ISO PMID:1465414 CAFA PMID:1465414 RGD:12792994 NCBI chrNW_004955437:20,482,589...20,487,337
Ensembl chrNW_004955437:20,482,589...20,488,249
JBrowse link
4-hydroxy-2-oxoglutarate aldolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 enables ISO (PMID:21998747) BHF-UCL PMID:21998747 NCBI chrNW_004955507:3,687,449...3,711,939
Ensembl chrNW_004955507:3,687,769...3,711,151
JBrowse link
5'-deoxyribose-5-phosphate lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmga1 high mobility group AT-hook 1 enables ISO (PMID:19465398) UniProt PMID:19465398 NCBI chrNW_004955437:2,478,414...2,486,809
Ensembl chrNW_004955437:2,478,414...2,486,809
JBrowse link
G Hmga2 high mobility group AT-hook 2 enables ISO (PMID:19465398) UniProt PMID:19465398 NCBI chrNW_004955458:12,493,790...12,624,805 JBrowse link
G Poll DNA polymerase lambda enables ISO (PMID:19806195) UniProt PMID:19806195 NCBI chrNW_004955485:8,691,886...8,700,681
Ensembl chrNW_004955485:8,691,453...8,703,872
JBrowse link
G Polq DNA polymerase theta enables ISO (PMID:19188258) UniProt PMID:19188258 NCBI chrNW_004955427:20,779,332...20,895,094
Ensembl chrNW_004955427:20,778,952...20,894,989
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 contributes_to ISO (PMID:20383123) UniProtKB PMID:20383123 NCBI chrNW_004955453:16,967,453...17,054,634
Ensembl chrNW_004955453:16,967,453...17,054,634
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 enables ISO (PMID:20383123) UniProt PMID:20383123 NCBI chrNW_004955413:27,135,785...27,158,344
Ensembl chrNW_004955413:27,135,805...27,159,750
JBrowse link
6-pyruvoyltetrahydropterin synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pts 6-pyruvoyltetrahydropterin synthase enables ISO (MGI:1328867|PMID:9894812) RGD
MGI
PMID:1939130 PMID:9894812 MGI:1328867 RGD:68294 NCBI chrNW_004955412:13,880,937...13,888,562
Ensembl chrNW_004955412:13,880,937...13,888,562
JBrowse link
aconitate decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 enables ISO (PMID:23610393)
(MGI:5490395|PMID:23610393)
(MGI:6357088|PMID:30635240)
UniProt PMID:23610393 PMID:30635240 MGI:5490395 MGI:6357088 NCBI chrNW_004955404:30,254,934...30,266,898
Ensembl chrNW_004955404:30,254,841...30,270,921
JBrowse link
aconitate hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 enables ISO (MGI:3028434|PMID:14726953), (MGI:3521564|PMID:15604406)
(PMID:1281544)
(PMID:1946430), (PMID:8041788)
RGD
MGI
CAFA
UniProt
PMID:1281544 PMID:1946430 PMID:8041788 PMID:9092825 PMID:11264001 More... MGI:3028434 MGI:3521564 RGD:1642739 RGD:1642740 NCBI chrNW_004955472:3,141,473...3,170,959
Ensembl chrNW_004955472:3,141,257...3,170,959
JBrowse link
G Aco2 aconitase 2 enables ISO (MGI:3522379|PMID:15317809), (MGI:3709427|PMID:17322295)
(PMID:1052766)
RGD
MGI
Reactome
PMID:1052766 PMID:9712727 PMID:12139479 PMID:14674759 PMID:15317809 More... MGI:3522379 MGI:3709427 RGD:2306852 RGD:2306877 RGD:632269 NCBI chrNW_004955413:27,027,341...27,065,227
Ensembl chrNW_004955413:27,027,341...27,065,227
JBrowse link
adenosylmethionine decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 enables ISO (MGI:3584197|PMID:11856372) RGD
MGI
PMID:1415709 PMID:10430362 PMID:11856372 PMID:21048303 MGI:3584197 RGD:1578320 RGD:7242909 RGD:7242912 NCBI chrNW_004955411:35,541,517...35,563,209
Ensembl chrNW_004955411:35,541,517...35,563,209
JBrowse link
adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 enables ISO (MGI:1344240|PMID:10482244) MGI PMID:10482244 MGI:1344240 NCBI chrNW_004955456:6,833,992...6,930,990
Ensembl chrNW_004955456:6,841,637...6,930,990
JBrowse link
G Adcy10 adenylate cyclase 10 enables ISO (PMID:12609998), (PMID:15659711) RGD
UniProt
PMID:7225326 PMID:9874775 PMID:12609998 PMID:15659711 RGD:1299450 RGD:2313177 NCBI chrNW_004955462:9,196,984...9,278,850
Ensembl chrNW_004955462:9,207,314...9,278,621
JBrowse link
G Adcy2 adenylate cyclase 2 enables ISO PMID:18164588
PMID:10427002
RGD
BHF-UCL
UniProt
PMID:1719547 PMID:10427002 PMID:11738086 PMID:12711600 PMID:18164588 RGD:10400857 RGD:2312641 RGD:2312674 RGD:724792 RGD:8553431 NCBI chrNW_004955504:4,990,634...5,376,990
Ensembl chrNW_004955504:5,004,903...5,376,328
JBrowse link
G Adcy3 adenylate cyclase 3 enables ISO PMID:24363043
(MGI:1889935|PMID:11055432)
UniProt PMID:11055432 PMID:24363043 MGI:1889935 RGD:10400870 NCBI chrNW_004955469:6,933,208...7,026,179
Ensembl chrNW_004955469:6,929,092...7,026,758
JBrowse link
G Adcy4 adenylate cyclase 4 enables ISO PMID:8900209 RGD
BHF-UCL
PMID:1946437 PMID:8900209 PMID:11738086 PMID:12711600 RGD:2312641 RGD:2312674 RGD:69739 RGD:8554340 NCBI chrNW_004955409:35,966,529...35,982,839
Ensembl chrNW_004955409:35,966,332...35,982,218
JBrowse link
G Adcy6 adenylate cyclase 6 enables ISO (MGI:4457984|PMID:20466003)
(MGI:3759160|PMID:17593019)
PMID:15385642
(PMID:17916776), (PMID:18403039), (PMID:23842570)
RGD
UniProt
MGI
BHF-UCL
PMID:11738086 PMID:12711600 PMID:15385642 PMID:15579502 PMID:15961389 More... MGI:3759160 MGI:4457984 RGD:1598749 RGD:2312641 RGD:2312674 RGD:2313211 RGD:2315004 RGD:8554216 NCBI chrNW_004955500:7,635,946...7,655,579
Ensembl chrNW_004955500:7,637,089...7,651,162
JBrowse link
G Adcy7 adenylate cyclase 7 enables ISO (MGI:6162268|PMID:18205980)
(MGI:3813184|PMID:18541530), (MGI:4459338|PMID:20505140), (MGI:5460917|PMID:23178822), (MGI:6158806|PMID:23229509)
(PMID:18541530), (PMID:23178822), (PMID:23229509), (PMID:23842570)
(PMID:11113152), (PMID:17760784)
RGD
UniProt
PMID:11113152 PMID:12711600 PMID:17760784 PMID:18205980 PMID:18541530 More... MGI:3813184 MGI:4459338 MGI:5460917 MGI:6158806 MGI:6162268 RGD:2312674 NCBI chrNW_004955433:8,362,957...8,428,773
Ensembl chrNW_004955433:8,362,756...8,426,997
JBrowse link
G Adcy8 adenylate cyclase 8 enables ISO (MGI:1344240|PMID:10482244) MGI PMID:10482244 MGI:1344240 NCBI chrNW_004955461:5,497,708...5,725,574
Ensembl chrNW_004955461:5,497,628...5,725,574
JBrowse link
G Adcy9 adenylate cyclase 9 enables ISO (PMID:9628827)
(MGI:80863|PMID:8662814)
UniProt
MGI
PMID:8662814 PMID:9628827 MGI:80863 NCBI chrNW_004955442:13,310,289...13,433,816
Ensembl chrNW_004955442:13,310,289...13,434,971
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 contributes_to ISO RGD PMID:22122229 RGD:10401947 NCBI chrNW_004955471:11,367,318...11,422,199
Ensembl chrNW_004955471:11,367,282...11,424,273
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 contributes_to ISO RGD PMID:22122229 RGD:10401947 NCBI chrNW_004955471:11,303,478...11,349,512
Ensembl chrNW_004955471:11,303,242...11,351,190
JBrowse link
aminocarboxymuconate-semialdehyde decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase enables
NOT|enables
ISO (PMID:12140278), (PMID:17288562), (PMID:25392945)
(PMID:17288562)
RGD
UniProt
ParkinsonsUK-UCL
PMID:11802786 PMID:12140278 PMID:17288562 PMID:25392945 RGD:70243 NCBI chrNW_004955440:2,348,434...2,412,706
Ensembl chrNW_004955440:2,348,396...2,412,706
JBrowse link
arginine decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin2 antizyme inhibitor 2 NOT|enables ISO (MGI:3695330|PMID:16916800) MGI PMID:16916800 MGI:3695330 NCBI chrNW_004955452:11,304,345...11,330,370
Ensembl chrNW_004955452:11,303,499...11,330,555
JBrowse link
argininosuccinate lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase ISO RGD PMID:4062872 PMID:8586639 RGD:1599287 RGD:2300098 NCBI chrNW_004955456:8,409,767...8,419,915 JBrowse link
aromatic-L-amino-acid decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddc dopa decarboxylase enables ISO (MGI:5510279|PMID:23863468)
(PMID:16338639)
RGD
MGI
UniProt
PMID:3379830 PMID:10569946 PMID:12047348 PMID:12703659 PMID:16338639 More... MGI:5510279 RGD:4139893 RGD:4139897 RGD:4139900 RGD:727571 NCBI chrNW_004955456:3,513,779...3,582,851
Ensembl chrNW_004955456:3,513,042...3,582,911
JBrowse link
ATP-dependent NAD(P)H-hydrate dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naxd NAD(P)HX dehydratase enables ISO (PMID:30576410)
PMID:24611804
UniProt
MGI
PMID:24611804 PMID:30576410 RGD:10047272 NCBI chrNW_004955404:2,028,560...2,049,638
Ensembl chrNW_004955404:2,029,539...2,047,211
JBrowse link
calcium- and calmodulin-responsive adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 ISO RGD PMID:14985420 RGD:2312640 NCBI chrNW_004955456:6,833,992...6,930,990
Ensembl chrNW_004955456:6,841,637...6,930,990
JBrowse link
G Adcy3 adenylate cyclase 3 ISO RGD PMID:12711600 RGD:2312674 NCBI chrNW_004955469:6,933,208...7,026,179
Ensembl chrNW_004955469:6,929,092...7,026,758
JBrowse link
G Adcy6 adenylate cyclase 6 enables ISO (MGI:50273|PMID:1379717) RGD
MGI
PMID:1379717 PMID:10894801 MGI:50273 RGD:2315006 NCBI chrNW_004955500:7,635,946...7,655,579
Ensembl chrNW_004955500:7,637,089...7,651,162
JBrowse link
G Adcy8 adenylate cyclase 8 enables ISO (MGI:1860567|PMID:10864938)
PMID:19158400
PMID:13680124
PMID:8557635
PMID:11856299
RGD
UniProt
PMID:8163524 PMID:8557635 PMID:10864938 PMID:11856299 PMID:13680124 More... MGI:1860567 RGD:13800543 RGD:13800545 RGD:13825188 RGD:2312682 RGD:69741 NCBI chrNW_004955461:5,497,708...5,725,574
Ensembl chrNW_004955461:5,497,628...5,725,574
JBrowse link
carbon-carbon lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hacl1 2-hydroxyacyl-CoA lyase 1 enables ISO (PMID:28289220)
(PMID:10468558), (PMID:15644336)
(MGI:6105330|PMID:28629946)
UniProt
HGNC-UCL
PMID:10468558 PMID:15644336 PMID:28289220 PMID:28629946 MGI:6105330 RGD:708588 NCBI chrNW_004955430:2,055,774...2,096,260
Ensembl chrNW_004955430:2,053,640...2,096,432
JBrowse link
carbonate dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca1 carbonic anhydrase 1 enables ISO (PMID:7758465) CACAO PMID:7758465 NCBI chrNW_004955417:3,270,619...3,313,261
Ensembl chrNW_004955417:3,270,619...3,305,756
JBrowse link
G Ca12 carbonic anhydrase 12 enables ISO (MGI:3037519|PMID:14660577) MGI PMID:14660577 MGI:3037519 NCBI chrNW_004955450:11,927,730...11,975,553
Ensembl chrNW_004955450:11,943,340...11,975,928
JBrowse link
G Ca13 carbonic anhydrase 13 enables ISO (MGI:3763759|PMID:14600151) MGI PMID:14600151 MGI:3763759 NCBI chrNW_004955417:3,194,961...3,219,019
Ensembl chrNW_004955417:3,194,501...3,219,755
JBrowse link
G Ca14 carbonic anhydrase 14 enables ISO (MGI:3037519|PMID:14660577) MGI PMID:14660577 MGI:3037519 NCBI chrNW_004955413:510,089...516,892
Ensembl chrNW_004955413:510,089...516,892
JBrowse link
G Ca2 carbonic anhydrase 2 enables ISO (MGI:3037519|PMID:14660577)
(MGI:5506965|PMID:23881097)
(PMID:7758465)
RGD
MGI
CACAO
PMID:6425289 PMID:7758465 PMID:14660577 PMID:23881097 MGI:3037519 MGI:5506965 RGD:1600729 NCBI chrNW_004955417:3,388,110...3,402,798
Ensembl chrNW_004955417:3,386,087...3,402,363
JBrowse link
G Ca4 carbonic anhydrase 4 enables ISO (MGI:3037519|PMID:14660577), (MGI:3696913|PMID:16083424) RGD
MGI
PMID:1533109 PMID:14660577 PMID:16083424 MGI:3037519 MGI:3696913 RGD:1600753 NCBI chrNW_004955451:1,485,939...1,493,249
Ensembl chrNW_004955451:1,486,010...1,494,084
JBrowse link
G Ca5a carbonic anhydrase 5A enables ISO (MGI:1889881|PMID:10677517), (MGI:3763759|PMID:14600151), (MGI:68736|PMID:7929150) RGD
MGI
PMID:7929150 PMID:7937950 PMID:10677517 PMID:14600151 MGI:1889881 MGI:3763759 MGI:68736 RGD:69789 NCBI chrNW_004955541:2,141,450...2,159,955
Ensembl chrNW_004955541:2,139,920...2,160,597
JBrowse link
G Ca5b carbonic anhydrase 5B enables ISO (MGI:1889881|PMID:10677517) MGI PMID:10677517 MGI:1889881 NCBI chrNW_004955519:2,415,722...2,455,052
Ensembl chrNW_004955519:2,412,289...2,455,280
JBrowse link
G Ca7 carbonic anhydrase 7 enables ISO (MGI:5506965|PMID:23881097) MGI PMID:23881097 MGI:5506965 NCBI chrNW_004955433:23,365,832...23,374,517
Ensembl chrNW_004955433:23,365,718...23,374,548
JBrowse link
carboxy-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Echdc1 ethylmalonyl-CoA decarboxylase 1 enables ISO (MGI:5306857|PMID:22016388) UniProt PMID:22016388 MGI:5306857 NCBI chrNW_004955436:8,332,066...8,365,200
Ensembl chrNW_004955436:8,332,066...8,365,200
JBrowse link
class I DNA-(apurinic or apyrimidinic site) endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase enables ISO (PMID:19959401) UniProt PMID:19959401 NCBI chrNW_004955438:1,531,114...1,556,483
Ensembl chrNW_004955438:1,531,114...1,556,481
JBrowse link
G Nthl1 nth like DNA glycosylase 1 enables ISO (PMID:8990169) FlyBase PMID:8990169 NCBI chrNW_004955442:15,210,799...15,223,272
Ensembl chrNW_004955442:15,217,019...15,223,272
JBrowse link
crotonyl-CoA hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdyl chromodomain Y like enables ISO (PMID:28803779) UniProt PMID:28803779 NCBI chrNW_004955465:8,570,197...8,780,551
Ensembl chrNW_004955465:8,568,121...8,780,569
JBrowse link
cyclic pyranopterin monophosphate synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mocs1 molybdenum cofactor synthesis 1 enables ISO (MGI:3757917|PMID:17236133)
(PMID:15180982)
MGI PMID:15180982 PMID:17236133 MGI:3757917 NCBI chrNW_004955437:6,840,451...6,870,685
Ensembl chrNW_004955437:6,840,451...6,870,685
JBrowse link
cystathionine beta-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cth cystathionine gamma-lyase ISO RGD PMID:9359866 RGD:1359024 NCBI chrNW_004955423:21,542,587...21,567,935
Ensembl chrNW_004955423:21,542,179...21,567,786
JBrowse link
cystathionine beta-synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta-synthase enables ISO (MGI:1888627|PMID:10953023), (MGI:71081|PMID:7878023)
(PMID:18776696), (PMID:19010420), (PMID:22985361), (PMID:23981774), (PMID:24416422), (PMID:7929220)
RGD
MGI
UniProt
PMID:7878023 PMID:7929220 PMID:9359866 PMID:10953023 PMID:18776696 More... MGI:1888627 MGI:71081 RGD:1359024 NCBI chrNW_004955407:38,924,355...38,939,790 JBrowse link
cystathionine gamma-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cth cystathionine gamma-lyase enables ISO (PMID:10212249), (PMID:19019829), (PMID:19428278)
(MGI:3046000|PMID:15038791)
UniProt
MGI
PMID:10212249 PMID:15038791 PMID:19019829 PMID:19428278 MGI:3046000 NCBI chrNW_004955423:21,542,587...21,567,935
Ensembl chrNW_004955423:21,542,179...21,567,786
JBrowse link
cysteine-S-conjugate beta-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kyat1 kynurenine aminotransferase 1 enables ISO (PMID:7883047) RGD
FlyBase
PMID:1723851 PMID:7883047 RGD:9685041 NCBI chrNW_004955570:1,211,950...1,260,561 JBrowse link
cytidylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 contributes_to ISO RGD PMID:22122229 RGD:10401947 NCBI chrNW_004955471:11,367,318...11,422,199
Ensembl chrNW_004955471:11,367,282...11,424,273
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 contributes_to ISO RGD PMID:22122229 RGD:10401947 NCBI chrNW_004955471:11,303,478...11,349,512
Ensembl chrNW_004955471:11,303,242...11,351,190
JBrowse link
D-glutamate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dglucy D-glutamate cyclase enables ISO (MGI:5901965|PMID:28266638) UniProt PMID:28266638 MGI:5901965 NCBI chrNW_004955438:13,440,883...13,554,969
Ensembl chrNW_004955438:13,489,999...13,545,523
JBrowse link
deoxyribodipyrimidine photo-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cry1 cryptochrome circadian regulator 1 NOT|enables ISO (PMID:8909283) UniProt PMID:8909283 NCBI chrNW_004955405:40,878,227...40,941,664
Ensembl chrNW_004955405:40,874,322...40,941,664
JBrowse link
G Cry2 cryptochrome circadian regulator 2 NOT|enables ISO (PMID:8909283) UniProt PMID:8909283 NCBI chrNW_004955422:2,084,020...2,114,980
Ensembl chrNW_004955422:2,083,138...2,115,072
JBrowse link
deoxyribose-phosphate aldolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dera deoxyribose-phosphate aldolase enables ISO (PMID:9226884) UniProt PMID:9226884 NCBI chrNW_004955413:12,571,341...12,682,985
Ensembl chrNW_004955413:12,571,176...12,685,852
JBrowse link
diphosphomevalonate decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mvd mevalonate diphosphate decarboxylase enables ISO (PMID:11792727), (PMID:14680974) RGD
UniProt
PMID:197206 PMID:9348097 PMID:11792727 PMID:14680974 RGD:2311302 RGD:2316852 NCBI chrNW_004955541:2,578,584...2,581,823
Ensembl chrNW_004955541:2,579,074...2,581,821
JBrowse link
DNA (6-4) photolyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cry1 cryptochrome circadian regulator 1 NOT|enables ISO (PMID:8909283) UniProt PMID:8909283 NCBI chrNW_004955405:40,878,227...40,941,664
Ensembl chrNW_004955405:40,874,322...40,941,664
JBrowse link
G Cry2 cryptochrome circadian regulator 2 NOT|enables ISO (PMID:8909283) UniProt PMID:8909283 NCBI chrNW_004955422:2,084,020...2,114,980
Ensembl chrNW_004955422:2,083,138...2,115,072
JBrowse link
enoyl-CoA hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Auh AU RNA binding methylglutaconyl-CoA hydratase enables ISO (PMID:7892223)
(MGI:1332868|PMID:10072761)
UniProt
MGI
PMID:7892223 PMID:10072761 MGI:1332868 NCBI chrNW_004955515:971,778...1,124,019
Ensembl chrNW_004955515:971,800...1,123,474
JBrowse link
G Echdc3 enoyl-CoA hydratase domain containing 3 enables ISO PMID:11009615 UniProt PMID:11009615 RGD:30309943 NCBI chrNW_004955421:27,712,527...27,731,141
Ensembl chrNW_004955421:27,712,528...27,730,623
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 enables ISO (PMID:26251176) RGD
UniProt
PMID:7993901 PMID:12379132 PMID:26251176 RGD:2317611 RGD:2317616 NCBI chrNW_004955477:11,012,451...11,021,487
Ensembl chrNW_004955477:11,012,451...11,021,486
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO RGD PMID:1730633 PMID:8253773 RGD:1600572 RGD:632874 NCBI chrNW_004955469:8,183,945...8,233,869
Ensembl chrNW_004955469:8,183,945...8,233,869
JBrowse link
G Hsd17b4 hydroxysteroid 17-beta dehydrogenase 4 enables ISO (PMID:10706581), (PMID:15060085), (PMID:9482850) UniProt PMID:9482850 PMID:10706581 PMID:15060085 NCBI chrNW_004955408:39,041,028...39,136,867
Ensembl chrNW_004955408:39,040,840...39,138,338
JBrowse link
ethanolamine-phosphate phospho-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etnppl ethanolamine-phosphate phospho-lyase enables ISO (PMID:22241472) FlyBase PMID:22241472 NCBI chrNW_004955496:1,274,929...1,292,802
Ensembl chrNW_004955496:1,275,051...1,292,349
JBrowse link
FAD-AMP lyase (cyclizing) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tkfc triokinase and FMN cyclase enables ISO (PMID:16289032) UniProt PMID:16289032 NCBI chrNW_004955511:6,200,433...6,235,855
Ensembl chrNW_004955511:6,200,433...6,236,283
JBrowse link
ferrochelatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fech ferrochelatase enables ISO (PMID:15123683), (PMID:27599036), (PMID:8973195)
(MGI:2384247|PMID:12149233), (MGI:3041718|PMID:14981080), (MGI:3620268|PMID:16503645), (MGI:3696634|PMID:15496139)
(MGI:3794459|PMID:16306232), (MGI:3818407|PMID:17003376), (MGI:60976|PMID:8325637)
(MGI:1327758|PMID:9989256)
RGD
BHF-UCL
MGI
PMID:1316128 PMID:8325637 PMID:8973195 PMID:9989256 PMID:12149233 More... MGI:1327758 MGI:2384247 MGI:3041718 MGI:3620268 MGI:3696634 MGI:3794459 MGI:3818407 MGI:60976 RGD:1598931 NCBI chrNW_004955402:41,902,868...41,938,099
Ensembl chrNW_004955402:41,902,868...41,938,174
JBrowse link
formimidoyltetrahydrofolate cyclodeaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ftcd formimidoyltransferase cyclodeaminase enables ISO PMID:9677387
(PMID:2572277)
BHF-UCL PMID:2572277 PMID:9677387 RGD:10047259 NCBI chrNW_004955407:42,608,249...42,617,167
Ensembl chrNW_004955407:42,607,872...42,617,166
JBrowse link
fructose-1-phosphate aldolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B enables ISO (MGI:5634227|PMID:25637246)
(PMID:2649152)
MGI PMID:2649152 PMID:25637246 MGI:5634227 NCBI chrNW_004955419:24,377,427...24,389,909
Ensembl chrNW_004955419:24,377,427...24,389,909
JBrowse link
fructose-bisphosphate aldolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoa aldolase, fructose-bisphosphate A enables ISO (MGI:5634227|PMID:25637246)
(MGI:6101994|PMID:23495010)
(MGI:2157196|PMID:11785984)
MGI
CAFA
PMID:11785984 PMID:23495010 PMID:25637246 MGI:2157196 MGI:5634227 MGI:6101994 NCBI chrNW_004955493:6,904,931...6,910,682
Ensembl chrNW_004955493:6,904,091...6,908,959
JBrowse link
G Aldob aldolase, fructose-bisphosphate B enables ISO (MGI:83096|PMID:604178)
(MGI:5634227|PMID:25637246)
(PMID:10625657), (PMID:17576770), (PMID:9244396)
RGD
MGI
BHF-UCL
PMID:604178 PMID:8255543 PMID:9244396 PMID:9448062 PMID:10625657 More... MGI:5634227 MGI:83096 RGD:2302096 RGD:2302804 NCBI chrNW_004955419:24,377,427...24,389,909
Ensembl chrNW_004955419:24,377,427...24,389,909
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C enables ISO (PMID:15537755), (PMID:9244396) RGD
UniProt
PMID:198211 PMID:9244396 PMID:15537755 RGD:2301138 NCBI chrNW_004955481:4,576,913...4,580,999
Ensembl chrNW_004955481:4,576,913...4,580,999
JBrowse link
fumarate hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fh fumarate hydratase enables ISO (MGI:5496931|PMID:23643539)
(PMID:29456767)
(PMID:21498518)
(PMID:26237645), (PMID:30718813), (PMID:30761759)
RGD
UniProt
CACAO
PMID:938457 PMID:2914923 PMID:21498518 PMID:23643539 PMID:26237645 More... MGI:5496931 RGD:2306828 RGD:632664 NCBI chrNW_004955406:10,535,801...10,558,649
Ensembl chrNW_004955406:10,535,323...10,561,627
JBrowse link
gamma-glutamyl carboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ggcx gamma-glutamyl carboxylase ISO RGD PMID:12754193 RGD:1582507 NCBI chrNW_004955424:1,926,924...1,952,635
Ensembl chrNW_004955424:1,936,772...1,952,635
JBrowse link
gamma-glutamylaminecyclotransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ggact gamma-glutamylamine cyclotransferase enables ISO (PMID:20110353) UniProt PMID:20110353 NCBI chrNW_004955404:10,280,013...10,316,531 JBrowse link
gamma-glutamylcyclotransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ggct gamma-glutamylcyclotransferase enables ISO (PMID:18515354) UniProt PMID:18515354 NCBI chrNW_004955410:31,732,272...31,739,020 JBrowse link
GDP-mannose 4,6-dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gmds GDP-mannose 4,6-dehydratase enables ISO (PMID:9603974)
(PMID:9525924)
UniProt PMID:9525924 PMID:9603974 NCBI chrNW_004955465:11,133,513...11,562,562
Ensembl chrNW_004955465:11,145,837...11,563,352
JBrowse link
glutamate decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gad1 glutamate decarboxylase 1 enables ISO (PMID:10671565) RGD
UniProt
PMID:1924335 PMID:10671565 PMID:10812196 PMID:17712632 RGD:6480258 RGD:6480261 RGD:728511 NCBI chrNW_004955449:3,964,006...4,001,850
Ensembl chrNW_004955449:3,963,705...4,001,850
JBrowse link
G Gad2 glutamate decarboxylase 2 ISO RGD PMID:8999827 PMID:10812196 RGD:1625237 RGD:6480261 NCBI chrNW_004955429:3,092,977...3,170,128
Ensembl chrNW_004955429:3,096,453...3,169,259
JBrowse link
glyoxalase (glycolic acid-forming) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase enables ISO (PMID:31653696) UniProt PMID:31653696 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885
JBrowse link
GTP 3',8'-cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mocs1 molybdenum cofactor synthesis 1 enables ISO (MGI:3757917|PMID:17236133)
(PMID:15180982)
MGI PMID:15180982 PMID:17236133 MGI:3757917 NCBI chrNW_004955437:6,840,451...6,870,685
Ensembl chrNW_004955437:6,840,451...6,870,685
JBrowse link
guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 enables ISO (PMID:23505436) UniProt PMID:23505436 NCBI chrNW_004955471:11,367,318...11,422,199
Ensembl chrNW_004955471:11,367,282...11,424,273
JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 ISO RGD PMID:11121588 RGD:632921 NCBI chrNW_004955412:9,218,029...9,480,333
Ensembl chrNW_004955412:9,225,305...9,480,206
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 enables ISO (PMID:23505436) UniProt PMID:23505436 NCBI chrNW_004955471:11,303,478...11,349,512
Ensembl chrNW_004955471:11,303,242...11,351,190
JBrowse link
G Gucy2c guanylate cyclase 2C enables ISO (MGI:1097012|PMID:9294128) RGD
MGI
PMID:1701694 PMID:9294128 MGI:1097012 RGD:728418 NCBI chrNW_004955413:11,410,586...11,489,201
Ensembl chrNW_004955413:11,410,586...11,489,201
JBrowse link
G Gucy2d guanylate cyclase 2D, retinal enables ISO (MGI:5049799|PMID:21598940)
(PMID:21928830), (PMID:30319355)
RGD
UniProt
PMID:7831337 PMID:21598940 PMID:21928830 PMID:30319355 MGI:5049799 RGD:632891 NCBI chrNW_004955467:8,938,057...8,949,684
Ensembl chrNW_004955467:8,938,057...8,949,684
JBrowse link
G Gucy2f guanylate cyclase 2F, retinal ISO RGD PMID:7831337 RGD:632891 NCBI chrNW_004955490:6,331,247...6,437,563
Ensembl chrNW_004955490:6,331,247...6,437,563
JBrowse link
G Npr1 natriuretic peptide receptor 1 enables ISO (MGI:2179542|PMID:11997476)
(PMID:1672777)
RGD
MGI
UniProt
PMID:1672777 PMID:1679239 PMID:11997476 MGI:2179542 RGD:729136 NCBI chrNW_004955545:323,386...338,654
Ensembl chrNW_004955545:323,956...338,097
JBrowse link
G Npr2 natriuretic peptide receptor 2 enables ISO (PMID:26980729)
(MGI:2682104|PMID:14514678)
(PMID:1672777)
UniProt
MGI
PMID:1672777 PMID:14514678 PMID:26980729 MGI:2682104 NCBI chrNW_004955472:506,351...523,647
Ensembl chrNW_004955472:506,351...523,316
JBrowse link
histidine ammonia-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hal histidine ammonia-lyase enables ISO (MGI:52899|PMID:8486363)
(PMID:15806399)
RGD
MGI
Reactome
PMID:8486363 PMID:9432011 PMID:15806399 MGI:52899 RGD:632935 NCBI chrNW_004955405:32,317,345...32,341,409
Ensembl chrNW_004955405:32,316,326...32,341,485
JBrowse link
histidine decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdc histidine decarboxylase enables ISO (MGI:2138019|PMID:11478947)
(PMID:22767596)
RGD
MGI
UniProt
PMID:5898 PMID:4449071 PMID:7075603 PMID:9525922 PMID:11478947 More... MGI:2138019 RGD:2303726 RGD:2303727 RGD:2303728 RGD:2303733 RGD:2303734 RGD:2303735 NCBI chrNW_004955409:4,051,574...4,072,641
Ensembl chrNW_004955409:4,051,271...4,072,642
JBrowse link
holocytochrome-c synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102006165 cytochrome c-type heme lyase enables ISO (PMID:23150584) UniProt PMID:23150584 NCBI chrNW_004955544:2,105,486...2,117,830
Ensembl chrNW_004955544:2,103,815...2,117,838
JBrowse link
hydro-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca1 carbonic anhydrase 1 enables ISO (PMID:2114290) CACAO PMID:2114290 NCBI chrNW_004955417:3,270,619...3,313,261
Ensembl chrNW_004955417:3,270,619...3,305,756
JBrowse link
G L3hypdh trans-L-3-hydroxyproline dehydratase enables ISO (PMID:22528483)
(MGI:5437401|PMID:22528483)
UniProt PMID:22528483 MGI:5437401 NCBI chrNW_004955466:13,196,223...13,205,339
Ensembl chrNW_004955466:13,196,223...13,205,158
JBrowse link
G LOC102010839 cytochrome P450 2S1 enables ISO (PMID:21068195) UniProt PMID:21068195 NCBI chrNW_004955555:167,634...183,572
Ensembl chrNW_004955555:168,139...182,196
JBrowse link
hydroperoxy icosatetraenoate dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbxas1 thromboxane A synthase 1 enables ISO (PMID:17459323) UniProt PMID:17459323 NCBI chrNW_004955494:3,161,032...3,321,974
Ensembl chrNW_004955494:3,160,653...3,334,411
JBrowse link
hydroxymethylglutaryl-CoA lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase enables ISO (PMID:12464283), (PMID:22847177), (PMID:22865860), (PMID:8027038), (PMID:8670134), (PMID:9200711), (PMID:9869651) RGD
UniProt
PMID:2573547 PMID:8027038 PMID:8670134 PMID:9200711 PMID:9869651 More... RGD:1599519 NCBI chrNW_004955452:3,720,103...3,734,730
Ensembl chrNW_004955452:3,720,103...3,735,192
JBrowse link
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1 enables ISO (PMID:22847177), (PMID:22865860) UniProt PMID:22847177 PMID:22865860 NCBI chrNW_004955411:760,660...881,415
Ensembl chrNW_004955411:795,145...880,033
JBrowse link
L-allo-threonine aldolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shmt1 serine hydroxymethyltransferase 1 ISO RGD PMID:3110140 RGD:2300383 NCBI chrNW_004955478:10,972,791...11,001,535
Ensembl chrNW_004955478:10,978,139...11,001,202
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 ISO RGD PMID:3110140 RGD:2300383 NCBI chrNW_004955458:4,957,614...4,962,691
Ensembl chrNW_004955458:4,957,602...4,962,691
JBrowse link
L-cystine L-cysteine-lyase (deaminating) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cth cystathionine gamma-lyase enables ISO (PMID:22169477)
(MGI:5315686|PMID:19903941)
(MGI:5304595|PMID:22244329)
UniProt PMID:19903941 PMID:22169477 PMID:22244329 MGI:5304595 MGI:5315686 NCBI chrNW_004955423:21,542,587...21,567,935
Ensembl chrNW_004955423:21,542,179...21,567,786
JBrowse link
L-dopa decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddc dopa decarboxylase enables ISO (PMID:19703902) ParkinsonsUK-UCL PMID:19703902 NCBI chrNW_004955456:3,513,779...3,582,851
Ensembl chrNW_004955456:3,513,042...3,582,911
JBrowse link
L-fuconate dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enosf1 enolase superfamily member 1 enables ISO (PMID:24697329) UniProt PMID:24697329 NCBI chrNW_004955402:9,266,198...9,297,897
Ensembl chrNW_004955402:9,266,192...9,295,115
JBrowse link
L-serine ammonia-lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sds serine dehydratase enables ISO (PMID:15689518), (PMID:18342636) UniProt PMID:15689518 PMID:18342636 NCBI chrNW_004955482:9,646,523...9,653,471
Ensembl chrNW_004955482:9,643,919...9,653,375
JBrowse link
G Srr serine racemase enables ISO (PMID:18812225) UniProt PMID:18812225 NCBI chrNW_004955481:919,692...940,066
Ensembl chrNW_004955481:871,654...937,770
JBrowse link
lactoylglutathione lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glo1 glyoxalase I enables ISO (MGI:48978|PMID:1914521), (MGI:5300615|PMID:22171037), (MGI:54356|PMID:910130), (MGI:54475|PMID:566476), (MGI:54917|PMID:7444718), (MGI:55148|PMID:7323947), (MGI:55177|PMID:7333654), (MGI:5526937|PMID:18695250)
(PMID:11489834), (PMID:9705294)
RGD
UniProt
PMID:566476 PMID:910130 PMID:1914521 PMID:7323947 PMID:7333654 More... MGI:48978 MGI:5300615 MGI:54356 MGI:54475 MGI:54917 MGI:55148 MGI:55177 MGI:5526937 RGD:1627641 RGD:1641958 RGD:1641959 NCBI chrNW_004955437:4,728,709...4,749,834
Ensembl chrNW_004955437:4,728,709...4,749,834
JBrowse link
leukotriene-C4 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstm4 glutathione S-transferase mu 4 enables ISO (PMID:27791009) UniProt PMID:27791009 NCBI chrNW_004955435:13,064,691...13,069,734
Ensembl chrNW_004955435:13,063,966...13,210,264
JBrowse link
G Ltc4s leukotriene C4 synthase enables ISO (PMID:8706658), (PMID:9153254)
(MGI:3028458|PMID:11319240), (MGI:81677|PMID:8706658)
RGD
UniProt
MGI
PMID:8706658 PMID:9153254 PMID:11319240 PMID:12767051 PMID:17194456 MGI:3028458 MGI:81677 RGD:1599839 RGD:724432 NCBI chrNW_004955408:788,856...791,505 JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 enables ISO (PMID:23409838), (PMID:8703034), (PMID:9092565) RGD
BHF-UCL
PMID:8703034 PMID:9092565 PMID:14637132 PMID:23409838 RGD:2302289 NCBI chrNW_004955428:4,006,054...4,049,497
Ensembl chrNW_004955428:4,014,810...4,037,901
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 enables ISO (PMID:9278457) BHF-UCL PMID:9278457 NCBI chrNW_004955462:11,024,678...11,041,851
Ensembl chrNW_004955462:11,024,789...11,031,282
JBrowse link
long-chain-enoyl-CoA hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO RGD PMID:1730633 RGD:1600572 NCBI chrNW_004955469:8,183,945...8,233,869
Ensembl chrNW_004955469:8,183,945...8,233,869
JBrowse link
G Hsd17b4 hydroxysteroid 17-beta dehydrogenase 4 enables ISO (PMID:10400999), (PMID:9089413), (PMID:9482850) UniProt PMID:9089413 PMID:9482850 PMID:10400999 NCBI chrNW_004955408:39,041,028...39,136,867
Ensembl chrNW_004955408:39,040,840...39,138,338
JBrowse link
methylthioribulose 1-phosphate dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein enables ISO (PMID:24367089) UniProt PMID:24367089 NCBI chrNW_004955422:11,405,721...11,426,700
Ensembl chrNW_004955422:11,405,721...11,429,146
JBrowse link
N-acetylneuraminate lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npl N-acetylneuraminate pyruvate lyase enables ISO (MGI:5442449|PMID:22692205)
(PMID:11737202)
UniProt
MGI
PMID:11737202 PMID:22692205 MGI:5442449 NCBI chrNW_004955406:21,633,979...21,670,279
Ensembl chrNW_004955406:21,633,032...21,670,958
JBrowse link
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adsl adenylosuccinate lyase enables
NOT|enables
ISO (PMID:10888601), (PMID:16973378), (PMID:19405474)
(MGI:6718247|PMID:5891253)
RGD
MGI
UniProt
PMID:3689310 PMID:5891253 PMID:8887278 PMID:10888601 PMID:16973378 More... MGI:6718247 RGD:1598763 RGD:1598764 NCBI chrNW_004955413:26,067,463...26,084,669
Ensembl chrNW_004955413:26,067,516...26,088,527
JBrowse link
ornithine decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin2 antizyme inhibitor 2 NOT|enables ISO (MGI:3695330|PMID:16916800) MGI PMID:16916800 MGI:3695330 NCBI chrNW_004955452:11,304,345...11,330,370
Ensembl chrNW_004955452:11,303,499...11,330,555
JBrowse link
G Odc1 ornithine decarboxylase 1 enables ISO (MGI:3695330|PMID:16916800), (MGI:5574513|PMID:24967154), (MGI:62550|PMID:8328969)
(PMID:17900240)
RGD
MGI
UniProt
PMID:1415709 PMID:8328969 PMID:10430362 PMID:16916800 PMID:17900240 More... MGI:3695330 MGI:5574513 MGI:62550 RGD:1578320 RGD:7242912 NCBI chrNW_004955487:5,603,722...5,608,386
Ensembl chrNW_004955487:5,603,722...5,608,386
JBrowse link
orotidine-5'-phosphate decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Umps uridine monophosphate synthetase enables ISO (MGI:1289111|PMID:2419341), (MGI:6720227|PMID:965379), (MGI:6720228|PMID:3308878)
(PMID:11730338), (PMID:6893554)
RGD
MGI
UniProt
PMID:965379 PMID:2419341 PMID:3308878 PMID:6134725 PMID:6893554 More... MGI:1289111 MGI:6720227 MGI:6720228 RGD:5132277 NCBI chrNW_004955427:23,825,529...23,841,427
Ensembl chrNW_004955427:23,825,523...23,841,152
JBrowse link
oxaloacetate decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fahd1 fumarylacetoacetate hydrolase domain containing 1 enables ISO (PMID:25575590) UniProt PMID:25575590 NCBI chrNW_004955442:15,450,066...15,451,797 JBrowse link
peptidylamidoglycolate lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pam peptidylglycine alpha-amidating monooxygenase enables ISO PMID:10079066
(PMID:12699694)
RGD
UniProt
PMID:10079066 PMID:12699694 PMID:16405966 RGD:14390048 RGD:2302419 NCBI chrNW_004955418:10,953,044...11,107,668
Ensembl chrNW_004955418:10,953,696...11,107,667
JBrowse link
phosphatidylserine decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 enables ISO (MGI:58172|PMID:3242498) MGI PMID:3242498 MGI:58172 NCBI chrNW_004955507:5,346,937...5,370,072
Ensembl chrNW_004955507:5,346,838...5,370,072
JBrowse link
G Pisd phosphatidylserine decarboxylase enables ISO (PMID:30858161) UniProt PMID:30858161 NCBI chrNW_004955455:5,744,816...5,789,408
Ensembl chrNW_004955455:5,744,816...5,789,534
JBrowse link
phosphoenolpyruvate carboxykinase (GTP) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pck1 phosphoenolpyruvate carboxykinase 1 enables ISO (MGI:6119963|PMID:29230018)
PMID:26709450
(PMID:26792594)
PMID:26322521
PMID:31461616
(PMID:30193097), (PMID:32322062)
PMID:4186849
(PMID:26971250)
RGD
UniProt
BHF-UCL
PMID:4186849 PMID:6049928 PMID:16125296 PMID:26322521 PMID:26709450 More... MGI:6119963 RGD:13825433 RGD:1601233 RGD:2302971 RGD:30309906 RGD:30309918 RGD:30309937 RGD:8553288 NCBI chrNW_004955445:1,909,012...1,914,032
Ensembl chrNW_004955445:1,908,946...1,915,002
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2, mitochondrial ISO RGD PMID:6049928 RGD:2302971 NCBI chrNW_004955409:36,288,402...36,296,761
Ensembl chrNW_004955409:36,288,568...36,296,828
JBrowse link
phosphoenolpyruvate carboxykinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pck1 phosphoenolpyruvate carboxykinase 1 enables ISO (MGI:2157262|PMID:11792850) RGD
MGI
PMID:4303362 PMID:4353083 PMID:11440903 PMID:11792850 PMID:11820793 MGI:2157262 RGD:2302850 RGD:2302851 RGD:2302970 RGD:625518 NCBI chrNW_004955445:1,909,012...1,914,032
Ensembl chrNW_004955445:1,908,946...1,915,002
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2, mitochondrial ISO RGD PMID:4353083 PMID:11440903 RGD:2302851 RGD:2302970 NCBI chrNW_004955409:36,288,402...36,296,761
Ensembl chrNW_004955409:36,288,568...36,296,828
JBrowse link
phosphopantothenoylcysteine decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppcdc phosphopantothenoylcysteine decarboxylase enables ISO (PMID:11923312) UniProt PMID:11923312 NCBI chrNW_004955450:2,971,874...2,985,034
Ensembl chrNW_004955450:2,971,874...2,985,191
JBrowse link
phosphopyruvate hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 enables ISO (MGI:55148|PMID:7323947)
(PMID:3529090)
PMID:7964722
(PMID:29775581)
RGD
MGI
CAFA
UniProt
PMID:3529090 PMID:7323947 PMID:7964722 PMID:15041191 PMID:29775581 MGI:55148 RGD:12792993 RGD:2302788 NCBI chrNW_004955486:4,275,371...4,287,152
Ensembl chrNW_004955486:4,274,238...4,289,809
JBrowse link
G Eno2 enolase 2 enables ISO PMID:7964722 RGD
CAFA
PMID:7964722 PMID:8255543 PMID:15041191 PMID:15720133 RGD:12792993 RGD:2302788 RGD:2302795 RGD:2302804 NCBI chrNW_004955413:4,498,625...4,506,769
Ensembl chrNW_004955413:4,498,625...4,506,769
JBrowse link
G Eno3 enolase 3 enables ISO (MGI:3852306|PMID:17023274) RGD
MGI
PMID:8594891 PMID:17023274 MGI:3852306 RGD:2301765 NCBI chrNW_004955467:10,363,154...10,368,261
Ensembl chrNW_004955467:10,361,705...10,368,755
JBrowse link
G Eno4 enolase 4 enables ISO (MGI:5516566|PMID:23446454) MGI PMID:23446454 MGI:5516566 NCBI chrNW_004955431:21,625,808...21,650,282
Ensembl chrNW_004955431:21,625,808...21,650,282
JBrowse link
phosphoribosylaminoimidazole carboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase enables ISO (PMID:27590927) MGI PMID:27590927 NCBI chrNW_004955447:14,558,468...14,571,081
Ensembl chrNW_004955447:14,558,468...14,574,052
JBrowse link
phosphorus-oxygen lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd38 CD38 molecule enables ISO (MGI:2652315|PMID:12403647) MGI PMID:12403647 MGI:2652315 NCBI chrNW_004955480:8,177,178...8,218,483
Ensembl chrNW_004955480:8,178,473...8,217,643
JBrowse link
porphobilinogen synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase enables ISO (MGI:53493|PMID:4959158), (MGI:53609|PMID:4981581), (MGI:63121|PMID:14050799)
(PMID:11032836), (PMID:8175643)
RGD
MGI
CAFA
PMID:4959158 PMID:4981581 PMID:8175643 PMID:11032836 PMID:14050799 More... MGI:53493 MGI:53609 MGI:63121 RGD:4144201 NCBI chrNW_004955419:14,093,010...14,104,376
Ensembl chrNW_004955419:14,093,010...14,104,545
JBrowse link
protein deglycase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase NOT|enables ISO (PMID:31653696)
(PMID:25416785)
UniProt
ParkinsonsUK-UCL
PMID:25416785 PMID:31653696 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885
JBrowse link
selenocysteine lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scly selenocysteine lyase enables ISO PMID:20164179 CAFA PMID:20164179 RGD:12793035 NCBI chrNW_004955542:2,453,826...2,472,951
Ensembl chrNW_004955542:2,454,708...2,472,851
JBrowse link
sphinganine-1-phosphate aldolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sgpl1 sphingosine-1-phosphate lyase 1 enables ISO (PMID:14570870), (PMID:24809814)
(PMID:28165339)
UniProt PMID:14570870 PMID:24809814 PMID:28165339 NCBI chrNW_004955437:20,489,641...20,547,105
Ensembl chrNW_004955437:20,488,330...20,547,171
JBrowse link
sulfinoalanine decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csad cysteine sulfinic acid decarboxylase enables ISO PMID:9635011 RGD
UniProt
PMID:8029009 PMID:9635011 RGD:13800536 RGD:632638 NCBI chrNW_004955458:423,156...449,763
Ensembl chrNW_004955458:423,085...433,429
JBrowse link
UDP-glucuronate decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uxs1 UDP-glucuronate decarboxylase 1 enables ISO (PMID:23072385), (PMID:23656592) RGD
UniProt
PMID:11877387 PMID:23072385 PMID:23656592 RGD:625412 NCBI chrNW_004955470:10,661,210...10,706,504
Ensembl chrNW_004955470:10,659,520...10,706,269
JBrowse link
urocanate hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uroc1 urocanate hydratase 1 enables ISO (PMID:19304569) BHF-UCL PMID:19304569 NCBI chrNW_004955421:21,734,910...21,765,754
Ensembl chrNW_004955421:21,732,262...21,765,772
JBrowse link
uroporphyrinogen decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Urod uroporphyrinogen decarboxylase enables ISO (MGI:1929011|PMID:11134514), (MGI:3703836|PMID:17360334)
(MGI:80651|PMID:8661721)
(PMID:18004775)
RGD
MGI
UniProt
PMID:8661721 PMID:11134514 PMID:15736160 PMID:17360334 PMID:18004775 MGI:1929011 MGI:3703836 MGI:80651 RGD:2301379 NCBI chrNW_004955464:13,226,271...13,228,908
Ensembl chrNW_004955464:13,221,551...13,229,253
JBrowse link
uroporphyrinogen-III synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmbs hydroxymethylbilane synthase ISO in the presence of tetrahydropteroylglutamate RGD PMID:6466301 RGD:2303402 NCBI chrNW_004955412:20,192,519...20,202,635
Ensembl chrNW_004955412:20,192,522...20,202,635
JBrowse link
G Uros uroporphyrinogen III synthase contributes_to
enables
ISO (MGI:72967|PMID:7607680)
(PMID:18004775), (PMID:3174619), (PMID:3805019)
RGD
MGI
UniProt
PMID:3174619 PMID:3805019 PMID:6604545 PMID:7607680 PMID:18004775 MGI:3620006 MGI:72967 RGD:2303403 NCBI chrNW_004955477:3,673,583...3,707,761
Ensembl chrNW_004955477:3,673,532...3,707,760
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14045
    catalytic activity 3549
      lyase activity 134
        3'-deoxyribose phosphate lyase activity 0
        alkylmercury lyase activity 0
        carbon phosphorus lyase activity + 0
        carbon-carbon lyase activity + 40
        carbon-halide lyase activity + 0
        carbon-nitrogen lyase activity + 9
        carbon-oxygen lyase activity + 51
        carbon-sulfur lyase activity + 10
        ferrochelatase activity + 1
        indoleacetaldoxime dehydratase activity 0
        phosphorus-oxygen lyase activity + 20
        sirohydrochlorin cobaltochelatase activity 0
paths to the root