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ONTOLOGY REPORT - ANNOTATIONS

Term:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
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Accession:GO:0016814 term browser browse the term
Definition:Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.
Synonyms:xref: EC:3.5.4

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hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936870:25,039...34,601
Ensembl chrNW_004936870:25,039...34,601 		JBrowse link
2'-deoxyadenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase enables ISO (PMID:10720488)
(PMID:9361033) 		MGI
UniProt		 PMID:9361033 PMID:10720488 NCBI chrNW_004936530:2,217,713...2,224,070 JBrowse link
adenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase enables IEA
ISO 		InterPro
UniProt
TreeGrafter
RGD		 PMID:3746429 PMID:4462574 PMID:6815190 PMID:11038259 PMID:12675911 GO_REF:0000002 GO_REF:0000117 GO_REF:0000118 RGD:2291853 RGD:2291855 RGD:2291857 RGD:2291861 RGD:631747 NCBI chrNW_004936530:2,217,713...2,224,070 JBrowse link
G Ada2 adenosine deaminase 2 enables ISO (PMID:20147294) UniProt PMID:20147294 NCBI chrNW_004936807:232,851...262,593 JBrowse link
G Adad1 adenosine deaminase domain containing 1 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936662:1,533,088...1,570,201
Ensembl chrNW_004936662:1,533,082...1,570,157 		JBrowse link
G Adad2 adenosine deaminase domain containing 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936641:3,641,123...3,645,624
Ensembl chrNW_004936641:3,641,215...3,645,742 		JBrowse link
G Adar adenosine deaminase RNA specific enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936580:4,183,016...4,208,341
Ensembl chrNW_004936580:4,183,079...4,203,435 		JBrowse link
G Adarb1 adenosine deaminase RNA specific B1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936778:1,056,259...1,137,772
Ensembl chrNW_004936778:1,053,871...1,137,828 		JBrowse link
G Adarb2 adenosine deaminase RNA specific B2 (inactive) enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936484:12,400,903...12,876,572
Ensembl chrNW_004936484:12,401,502...12,875,689 		JBrowse link
G Adat1 adenosine deaminase tRNA specific 1 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936475:24,244,412...24,291,111
Ensembl chrNW_004936475:24,266,285...24,289,841 		JBrowse link
G LOC101972479 adenosine deaminase-like enables IEA TreeGrafter
UniProt		 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936530:2,034,514...2,041,099 JBrowse link
G LOC101974441 purine nucleoside phosphorylase LACC1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936791:80,245...91,172
Ensembl chrNW_004936791:80,245...93,951 		JBrowse link
G Mapda N6-Methyl-AMP deaminase enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936471:6,501,887...6,541,796
Ensembl chrNW_004936471:6,501,891...6,524,141 		JBrowse link
AMP deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd1 adenosine monophosphate deaminase 1 enables IEA UniProt
TreeGrafter
InterPro
RHEA
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936627:33,350...57,231
Ensembl chrNW_004936627:33,350...57,166 		JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 enables IEA UniProt
Ensembl
TreeGrafter
InterPro
RHEA		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936704:1,092,180...1,111,722
Ensembl chrNW_004936704:1,099,816...1,113,887 		JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 enables ISO
IEA 		RGD
UniProt
InterPro
RHEA
TreeGrafter		 PMID:9291127 GO_REF:0000002 GO_REF:0000003 GO_REF:0000116 GO_REF:0000117 GO_REF:0000118 RGD:632203 NCBI chrNW_004936528:7,847,156...7,891,585
Ensembl chrNW_004936528:7,848,096...7,890,627 		JBrowse link
cytidine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase enables IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936870:25,039...34,601
Ensembl chrNW_004936870:25,039...34,601 		JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 enables IEA
ISO 		TreeGrafter
RGD		 PMID:8511591 GO_REF:0000118 RGD:634661 NCBI chrNW_004939393:628...6,234
Ensembl chrNW_004939393:628...6,201 		JBrowse link
G Apobec2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 enables IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936476:18,759,040...18,769,815
Ensembl chrNW_004936476:18,758,582...18,769,835 		JBrowse link
G Cda cytidine deaminase enables ISO
IEA 		RGD
RHEA
TreeGrafter
Ensembl
UniProt
InterPro		 PMID:675715 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117 GO_REF:0000118 RGD:2316616 NCBI chrNW_004936474:6,543,295...6,564,575
Ensembl chrNW_004936474:6,543,220...6,566,308 		JBrowse link
G Cdadc1 cytidine and dCMP deaminase domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936565:2,336,613...2,395,816
Ensembl chrNW_004936565:2,336,744...2,387,195 		JBrowse link
cytosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 ISO RGD PMID:12697753 RGD:1358271 NCBI chrNW_004939393:628...6,234
Ensembl chrNW_004939393:628...6,201 		JBrowse link
dCMP deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdadc1 cytidine and dCMP deaminase domain containing 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936565:2,336,613...2,395,816
Ensembl chrNW_004936565:2,336,744...2,387,195 		JBrowse link
G Dctd dCMP deaminase enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936554:6,088,544...6,110,274
Ensembl chrNW_004936554:6,088,538...6,118,976 		JBrowse link
GTP cyclohydrolase I activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 enables
NOT|enables 		ISO
IEA 		(PMID:11284739), (PMID:8068008) RGD
TreeGrafter
InterPro
UniProt
UniProt		 PMID:2557335 PMID:8068008 PMID:8486153 PMID:8702680 PMID:9636709 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000117 GO_REF:0000118 RGD:1601284 RGD:2298653 RGD:2298654 RGD:2298655 RGD:728623 NCBI chrNW_004936697:232,048...275,420 JBrowse link
G LOC101973044 GTP cyclohydrolase 1-like enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004937155:57,736...58,850 JBrowse link
guanine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gda guanine deaminase enables ISO
IEA 		RGD
Ensembl
UniProt
InterPro
TreeGrafter		 PMID:11784697 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 RGD:708341 NCBI chrNW_004936503:8,191,925...8,279,806
Ensembl chrNW_004936503:8,192,049...8,278,790 		JBrowse link
IMP cyclohydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase enables ISO
IEA 		RGD
InterPro
UniProt
Ensembl
TreeGrafter		 PMID:9332377 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 RGD:70804 NCBI chrNW_004936586:1,782,581...1,809,458
Ensembl chrNW_004936586:1,782,528...1,810,010 		JBrowse link
methenyltetrahydrofolate cyclohydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 enables IEA TreeGrafter
Ensembl
UniProt		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936495:8,100,977...8,170,244
Ensembl chrNW_004936495:8,100,912...8,171,800 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase enables IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936556:462,998...475,092
Ensembl chrNW_004936556:462,974...475,159 		JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like enables IEA TreeGrafter
UniProt		 GO_REF:0000003 GO_REF:0000118 NCBI chrNW_004936598:1,401,392...1,514,314
Ensembl chrNW_004936598:1,401,402...1,514,357 		JBrowse link
tRNA-specific adenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adad1 adenosine deaminase domain containing 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936662:1,533,088...1,570,201
Ensembl chrNW_004936662:1,533,082...1,570,157 		JBrowse link
G Adad2 adenosine deaminase domain containing 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936641:3,641,123...3,645,624
Ensembl chrNW_004936641:3,641,215...3,645,742 		JBrowse link
G Adar adenosine deaminase RNA specific enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936580:4,183,016...4,208,341
Ensembl chrNW_004936580:4,183,079...4,203,435 		JBrowse link
G Adarb1 adenosine deaminase RNA specific B1 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936778:1,056,259...1,137,772
Ensembl chrNW_004936778:1,053,871...1,137,828 		JBrowse link
G Adarb2 adenosine deaminase RNA specific B2 (inactive) enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936484:12,400,903...12,876,572
Ensembl chrNW_004936484:12,401,502...12,875,689 		JBrowse link
G Adat1 adenosine deaminase tRNA specific 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936475:24,244,412...24,291,111
Ensembl chrNW_004936475:24,266,285...24,289,841 		JBrowse link
G Adat2 adenosine deaminase tRNA specific 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936625:2,694,748...2,717,958
Ensembl chrNW_004936625:2,694,754...2,719,792 		JBrowse link
tRNA-specific adenosine-34 deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adat2 adenosine deaminase tRNA specific 2 enables IEA TreeGrafter
UniProt		 GO_REF:0000003 GO_REF:0000118 NCBI chrNW_004936625:2,694,748...2,717,958
Ensembl chrNW_004936625:2,694,754...2,719,792 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18191
    catalytic activity 5330
      hydrolase activity 2190
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 122
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 28
            1-pyrroline-4-hydroxy-2-carboxylate deaminase activity 0
            2'-deoxyadenosine deaminase activity 1
            5'-deoxyadenosine deaminase activity 0
            5'-methylthioadenosine deaminase activity 0
            8-oxoguanine deaminase activity 0
            N-cyclopropylammelide alkylamino hydrolase activity 0
            N-cyclopropylammeline deaminase activity 0
            N-cyclopropylmelamine deaminase activity 0
            S-adenosylhomocysteine deaminase activity 0
            adenine deaminase activity 0
            adenosine deaminase activity + 12
            adenosine-phosphate deaminase activity + 3
            aminoimidazolase activity 0
            blasticidin-S deaminase activity 0
            cAMP deaminase activity 0
            creatinine deaminase activity 0
            cyclohydrolase activity + 6
            cytidine deaminase activity 5
            cytosine deaminase activity 1
            dCMP deaminase activity 2
            dCTP deaminase (dUMP-forming) activity 0
            dCTP deaminase activity 0
            diaminohydroxyphosphoribosylaminopyrimidine deaminase activity 0
            dihydropterin deaminase activity 0
            guanine deaminase activity 1
            guanosine deaminase activity 0
            isoguanine deaminase activity 0
            pterin deaminase activity 0
            pyrithiamine deaminase activity 0
            sepiapterin deaminase activity 0
paths to the root