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ONTOLOGY REPORT - ANNOTATIONS

Term:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
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Accession:GO:0016814 term browser browse the term
Definition:Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.
Synonyms:xref: EC:3.5.4


show annotations for term's descendants           Sort by:
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:157,446,120...157,455,958
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
2'-deoxyadenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase enables ISO
IEA 		(PMID:9361033)
GO_REF:0000107
MGI:1857117 (PMID:10720488)
GO_REF:0000116 		RGD
Ensembl
RHEA		 PMID:9361033 PMID:10720488 GO_REF:0000107 GO_REF:0000116 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
adenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase enables IDA
IEA
ISO
IBA
ISS 		GO_REF:0000107
GO_REF:0000116
GO_REF:0000002
MGI:1857117|MGI:2681791|MGI:2683027 (PMID:11591798), (PMID:1618849), (PMID:16742956), (PMID:1914521), (PMID:2015347), (PMID:2387582), (PMID:6771472), (PMID:718989), (PMID:7592575), (PMID:7731963), (PMID:8064675), (PMID:8492116), (PMID:8634299), (PMID:8663040), (PMID:8672487), (PMID:8894685), (PMID:8942668), (PMID:9272950), (PMID:9478961)
GO_REF:0000033
GO_REF:0000117
(PMID:11999881), (PMID:16670267), (PMID:26166670), (PMID:3182793), (PMID:8452534), (PMID:8894685), (PMID:9361033)
GO_REF:0000024
PMID:19900420 		Ensembl
RHEA
InterPro
RGD
GO_Central
UniProt		 PMID:718989 PMID:1618849 PMID:1914521 PMID:2015347 PMID:2387582 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117, RGD:631747, RGD:2291853, RGD:2291855, RGD:2291857, RGD:2291861, RGD:155230730 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adad1 adenosine deaminase domain containing 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:119,948,809...120,005,920
Ensembl chr 2:119,948,926...120,005,913 		JBrowse link
G Adad2 adenosine deaminase domain containing 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:47,665,288...47,669,433
Ensembl chr19:47,665,309...47,669,436 		JBrowse link
G Adar adenosine deaminase, RNA-specific enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 enables IEA GO_REF:0000002
GO_REF:0000107 		InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Adarb2 adenosine deaminase RNA specific B2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831 		JBrowse link
G Adat1 adenosine deaminase, tRNA-specific 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:39,918,083...39,956,886
Ensembl chr19:39,918,227...39,956,883 		JBrowse link
G Lacc1 laccase domain containing 1 enables ISO (PMID:31978345) RGD PMID:31978345 NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545 		JBrowse link
AMP deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd1 adenosine monophosphate deaminase 1 enables IDA
IEA
ISO
IBA 		PMID:9133604
GO_REF:0000107
GO_REF:0000116
GO_REF:0000002
GO_REF:0000003
MGI:6157956 (PMID:27896074)
GO_REF:0000033
GO_REF:0000117
(PMID:11102975) 		Ensembl
RHEA
InterPro
UniProt
RGD
GO_Central		 PMID:11102975 PMID:27896074 PMID:9133604 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117, RGD:329845498 NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938 		JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 enables IEA
ISO
IBA 		GO_REF:0000003
GO_REF:0000002
MGI:5490144 (PMID:22212473), (PMID:23911318)
GO_REF:0000033
GO_REF:0000117
GO_REF:0000116
SGD:S000004498 (PMID:23911318) 		UniProt
InterPro
RGD
GO_Central
RHEA		 PMID:22212473 PMID:23911318 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 GO_REF:0000117 NCBI chr 2:195,707,609...195,720,454
Ensembl chr 2:195,707,610...195,720,271 		JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 enables IDA
IEA
ISO
IBA 		GO_REF:0000116
GO_REF:0000002
MGI:4364610|MGI:5529271 (PMID:23078545), (PMID:23542464), (PMID:23911318), (PMID:24066180), (PMID:24940686), (PMID:28746349), (PMID:9133604)
GO_REF:0000033
GO_REF:0000117
GO_REF:0000003 		RHEA
InterPro
RGD
GO_Central
UniProt		 PMID:9133604 PMID:23078545 PMID:23542464 PMID:23911318 PMID:24066180 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 GO_REF:0000117, RGD:632203 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887 		JBrowse link
cytidine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase enables ISO
IBA 		(PMID:18722174)
GO_REF:0000033
(PMID:10373455), (PMID:12692563), (PMID:24279473) 		RGD
GO_Central		 PMID:10373455 PMID:12692563 PMID:18722174 PMID:24279473 GO_REF:0000033 NCBI chr 4:157,446,120...157,455,958
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 enables IDA
IBA
NAS 		GO_REF:0000033
PMID:10781591
PMID:15448152 		GO_Central
RGD		 PMID:8511591 PMID:10781591 PMID:15448152 GO_REF:0000033, RGD:634661, RGD:8553657, RGD:8554599 NCBI chr 4:157,472,879...157,500,496
Ensembl chr 4:155,800,887...155,827,390 		JBrowse link
G Apobec2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 enables ISO
IEA 		(PMID:10403781)
GO_REF:0000107 		RGD
Ensembl		 PMID:10403781 GO_REF:0000107 NCBI chr 9:12,564,955...12,578,461
Ensembl chr 9:12,564,920...12,578,458 		JBrowse link
G Apobec3 apolipoprotein B mRNA editing enzyme catalytic subunit 3 enables ISO
IBA 		(PMID:16571802), (PMID:29290613)
GO_REF:0000033 		RGD
GO_Central		 PMID:16571802 PMID:29290613 GO_REF:0000033 NCBI chr 7:111,433,789...111,453,032
Ensembl chr 7:111,433,764...111,452,922 		JBrowse link
G Cda cytidine deaminase enables ISO
IEA
IBA 		(PMID:7923172), (PMID:9596658)
GO_REF:0000107
GO_REF:0000003
GO_REF:0000117
GO_REF:0000104
GO_REF:0000002
GO_REF:0000033
(PMID:16784234), (PMID:5651639) 		RGD
Ensembl
UniProt
InterPro
GO_Central		 PMID:5651639 PMID:7923172 PMID:9596658 PMID:16784234 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231 		JBrowse link
G Cdadc1 cytidine and dCMP deaminase domain containing 1 enables ISO (PMID:26945630) RGD PMID:26945630 NCBI chr15:33,726,590...33,755,611
Ensembl chr15:33,723,435...33,755,576 		JBrowse link
cytosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 IDA RGD PMID:12697753 RGD:1358271 NCBI chr 4:157,472,879...157,500,496
Ensembl chr 4:155,800,887...155,827,390 		JBrowse link
dCMP deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdadc1 cytidine and dCMP deaminase domain containing 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:33,726,590...33,755,611
Ensembl chr15:33,723,435...33,755,576 		JBrowse link
G Dctd dCMP deaminase enables IEA
IBA 		GO_REF:0000002
GO_REF:0000116
GO_REF:0000003
GO_REF:0000033 		InterPro
RHEA
UniProt
GO_Central		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr16:50,799,699...50,831,398
Ensembl chr16:44,055,128...44,098,446 		JBrowse link
GTP cyclohydrolase I activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 enables
NOT|enables 		IDA
IEA
ISO
IBA 		GO_REF:0000002
MGI:1856903 (PMID:19286659), (PMID:7524491)
GO_REF:0000033
GO_REF:0000117
(PMID:16778797), (PMID:7730309)
(PMID:8068008)
(PMID:11284739)
(PMID:3753653) 		InterPro
RGD
GO_Central
UniProt		 PMID:3753653 PMID:7524491 PMID:7730309 PMID:8068008 PMID:11284739 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000117, RGD:1601284, RGD:2298655, RGD:728623, RGD:2298654, RGD:2298653 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
guanine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gda guanine deaminase enables IDA
IEA
ISO
IBA 		GO_REF:0000116
GO_REF:0000003
GO_REF:0000002
(PMID:10075721), (PMID:8064675), (PMID:8226898)
GO_REF:0000033
GO_REF:0000104 		RHEA
UniProt
InterPro
RGD
GO_Central		 PMID:8064675 PMID:8226898 PMID:10075721 PMID:11784697 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000116, RGD:708341 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
IMP cyclohydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase enables IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000003
GO_REF:0000116
GO_REF:0000033
(PMID:6480832)
GO_REF:0000002
(PMID:26588576) 		Ensembl
UniProt
RHEA
GO_Central
RGD
InterPro		 PMID:6480832 PMID:26588576 PMID:9332377 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116, RGD:70804 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889 		JBrowse link
methenyltetrahydrofolate cyclohydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC134479019 bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like enables IBA
IEA 		GO_REF:0000033
GO_REF:0000003 		GO_Central
UniProt		 GO_REF:0000003 GO_REF:0000033
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 enables TAS
IEA
ISO
IBA
ISS 		GO_REF:0000116
MGI:1338850 (PMID:16150419)
GO_REF:0000033
GO_REF:0000024
(PMID:10828945), (PMID:1881876)
GO_REF:0000003 		RHEA
RGD
GO_Central
UniProt		 PMID:1881876 PMID:10828945 PMID:16150419 PMID:2186031 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116, RGD:1299513 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd1-ps1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1, pseudogene 1 enables IBA
IEA
ISS 		GO_REF:0000033
GO_REF:0000116
GO_REF:0000003
GO_REF:0000024 		GO_Central
RHEA
UniProt		 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 NCBI chr 3:116,195,791...116,198,973 JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase enables ISO
IEA
IBA 		(PMID:16100107)
GO_REF:0000107
GO_REF:0000003
(PMID:16150419), (PMID:2647744)
GO_REF:0000033 		RGD
Ensembl
UniProt
GO_Central		 PMID:2647744 PMID:16100107 PMID:16150419 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like enables IDA
IEA
IBA 		PMID:24733394
GO_REF:0000003
GO_REF:0000116
GO_REF:0000033 		UniProt
RHEA
GO_Central		 PMID:24733394 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116, RGD:150521648 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
tRNA-specific adenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adad1 adenosine deaminase domain containing 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:119,948,809...120,005,920
Ensembl chr 2:119,948,926...120,005,913 		JBrowse link
G Adad2 adenosine deaminase domain containing 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:47,665,288...47,669,433
Ensembl chr19:47,665,309...47,669,436 		JBrowse link
G Adar adenosine deaminase, RNA-specific enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Adarb2 adenosine deaminase RNA specific B2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831 		JBrowse link
G Adat1 adenosine deaminase, tRNA-specific 1 enables ISO
IEA
IBA 		(PMID:10430867)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:10430867 GO_REF:0000033 GO_REF:0000107 NCBI chr19:39,918,083...39,956,886
Ensembl chr19:39,918,227...39,956,883 		JBrowse link
G Adat2 adenosine deaminase, tRNA-specific 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:7,954,520...7,975,254
Ensembl chr 1:7,954,631...7,975,251 		JBrowse link
tRNA-specific adenosine-34 deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adat2 adenosine deaminase, tRNA-specific 2 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000003 		GO_Central
UniProt		 GO_REF:0000003 GO_REF:0000033 NCBI chr 1:7,954,520...7,975,254
Ensembl chr 1:7,954,631...7,975,251 		JBrowse link
G Adat3 adenosine deaminase, tRNA-specific 3 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:9,109,070...9,113,673
Ensembl chr 7:9,101,187...9,115,340 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21054
    catalytic activity 6213
      hydrolase activity 2572
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 127
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 28
            1-pyrroline-4-hydroxy-2-carboxylate deaminase activity 0
            2'-deoxyadenosine deaminase activity 1
            5'-deoxyadenosine deaminase activity 0
            5'-methylthioadenosine deaminase activity 0
            8-oxoguanine deaminase activity 0
            N-cyclopropylammelide alkylamino hydrolase activity 0
            N-cyclopropylammeline deaminase activity 0
            N-cyclopropylmelamine deaminase activity 0
            S-adenosylhomocysteine deaminase activity 0
            adenine deaminase activity 0
            adenosine deaminase activity + 10
            adenosine-phosphate deaminase activity + 3
            aminoimidazolase activity 0
            blasticidin-S deaminase activity 0
            cAMP deaminase activity 0
            creatinine deaminase activity 0
            cyclohydrolase activity + 7
            cytidine deaminase activity 6
            cytosine deaminase activity 1
            dCMP deaminase activity 2
            dCTP deaminase (dUMP-forming) activity 0
            dCTP deaminase activity 0
            diaminohydroxyphosphoribosylaminopyrimidine deaminase activity 0
            dihydropterin deaminase activity 0
            guanine deaminase activity 1
            guanosine deaminase activity 0
            isoguanine deaminase activity 0
            pterin deaminase activity 0
            pyrithiamine deaminase activity 0
            sepiapterin deaminase activity 0
paths to the root