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ONTOLOGY REPORT - ANNOTATIONS

Term:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
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Accession:GO:0016814 term browser browse the term
Definition:Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.
Synonyms:xref: EC:3.5.4

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hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624860:4,912,938...4,927,846
Ensembl chrNW_004624860:4,912,656...4,926,634 		JBrowse link
G LOC101722862 DNA dC->dU-editing enzyme APOBEC-3F-like enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624752:9,172,821...9,227,174 JBrowse link
2'-deoxyadenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase enables ISO (PMID:10720488)
(PMID:9361033) 		MGI
UniProt		 PMID:9361033 PMID:10720488 NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883 		JBrowse link
adenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase enables ISO
IEA 		RGD
TreeGrafter
UniProt
InterPro		 PMID:3746429 PMID:4462574 PMID:6815190 PMID:11038259 PMID:12675911 GO_REF:0000002 GO_REF:0000117 GO_REF:0000118 RGD:2291853 RGD:2291855 RGD:2291857 RGD:2291861 RGD:631747 NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883 		JBrowse link
G Ada2 adenosine deaminase 2 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624735:10,023,330...10,052,600 JBrowse link
G Adad1 adenosine deaminase domain containing 1 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624777:2,812,199...2,861,179
Ensembl chrNW_004624777:2,812,383...2,859,991 		JBrowse link
G Adad2 adenosine deaminase domain containing 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624746:3,393,426...3,399,388
Ensembl chrNW_004624746:3,391,742...3,399,452 		JBrowse link
G Adar adenosine deaminase RNA specific enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624885:2,783,058...2,839,688
Ensembl chrNW_004624885:2,812,448...2,839,693 		JBrowse link
G Adarb1 adenosine deaminase RNA specific B1 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624745:30,549,195...30,635,081
Ensembl chrNW_004624745:30,549,257...30,635,269 		JBrowse link
G Adarb2 adenosine deaminase RNA specific B2 (inactive) enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624775:9,089,839...9,646,985
Ensembl chrNW_004624775:9,090,545...9,643,355 		JBrowse link
G Adat1 adenosine deaminase tRNA specific 1 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624746:11,356,599...11,378,183 JBrowse link
G Lacc1 laccase domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624748:11,150,678...11,194,794
Ensembl chrNW_004624748:11,187,316...11,194,841 		JBrowse link
G LOC101697390 adenosine deaminase domain-containing protein 1-like enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624933:1,380,998...1,428,248 JBrowse link
G LOC101707801 adenosine deaminase domain-containing protein 1-like enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624824:8,872,087...8,893,064 JBrowse link
G Mapda N6-Methyl-AMP deaminase enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624804:10,438,845...10,463,086
Ensembl chrNW_004624804:10,445,758...10,462,648 		JBrowse link
AMP deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd1 adenosine monophosphate deaminase 1 enables IEA RHEA
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000116 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624772:10,320,837...10,350,237
Ensembl chrNW_004624772:10,320,735...10,348,464 		JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 enables IEA RHEA
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000116 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624772:5,335,303...5,346,569
Ensembl chrNW_004624772:5,335,082...5,349,887 		JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 enables ISO
IEA 		RGD
TreeGrafter
UniProt
InterPro
RHEA		 PMID:9291127 GO_REF:0000002 GO_REF:0000003 GO_REF:0000116 GO_REF:0000117 GO_REF:0000118 RGD:632203 NCBI chrNW_004624766:2,542,021...2,586,912
Ensembl chrNW_004624766:2,545,932...2,587,025 		JBrowse link
cytidine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624860:4,912,938...4,927,846
Ensembl chrNW_004624860:4,912,656...4,926,634 		JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 enables ISO
IEA 		RGD
TreeGrafter		 PMID:8511591 GO_REF:0000118 RGD:634661 NCBI chrNW_004624860:4,938,001...4,957,640
Ensembl chrNW_004624860:4,938,001...4,957,236 		JBrowse link
G Apobec2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624754:17,689,587...17,700,318
Ensembl chrNW_004624754:17,689,595...17,700,316 		JBrowse link
G Cda cytidine deaminase enables ISO
IEA 		RGD
TreeGrafter
UniProt
InterPro		 PMID:675715 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000117 GO_REF:0000118 RGD:2316616 NCBI chrNW_004624764:5,621,888...5,645,055
Ensembl chrNW_004624764:5,621,899...5,645,850 		JBrowse link
G Cdadc1 cytidine and dCMP deaminase domain containing 1 enables ISO (PMID:26945630) UniProt PMID:26945630 NCBI chrNW_004624748:5,420,395...5,467,215
Ensembl chrNW_004624748:5,426,215...5,467,082 		JBrowse link
G LOC101722862 DNA dC->dU-editing enzyme APOBEC-3F-like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624752:9,172,821...9,227,174 JBrowse link
cytosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 ISO RGD PMID:12697753 RGD:1358271 NCBI chrNW_004624860:4,938,001...4,957,640
Ensembl chrNW_004624860:4,938,001...4,957,236 		JBrowse link
dCMP deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdadc1 cytidine and dCMP deaminase domain containing 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624748:5,420,395...5,467,215
Ensembl chrNW_004624748:5,426,215...5,467,082 		JBrowse link
G Dctd dCMP deaminase enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624769:13,649,603...13,674,578
Ensembl chrNW_004624769:13,649,016...13,674,590 		JBrowse link
GTP cyclohydrolase I activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 NOT|enables ISO
IEA 		(PMID:11284739), (PMID:8068008) UniProt
TreeGrafter
UniProt
RGD
InterPro		 PMID:2557335 PMID:8068008 PMID:8486153 PMID:8702680 PMID:9636709 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000117 GO_REF:0000118 RGD:1601284 RGD:2298653 RGD:2298654 RGD:2298655 RGD:728623 NCBI chrNW_004624731:14,459,164...14,502,485
Ensembl chrNW_004624731:14,459,303...14,500,429 		JBrowse link
guanine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gda guanine deaminase enables ISO
IEA 		RGD
TreeGrafter
InterPro
UniProt
RHEA		 PMID:11784697 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000116 GO_REF:0000118 RGD:708341 NCBI chrNW_004624736:836,283...914,616
Ensembl chrNW_004624736:836,286...914,409 		JBrowse link
IMP cyclohydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase enables ISO
IEA 		RGD
Ensembl
TreeGrafter
InterPro
UniProt		 PMID:9332377 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 RGD:70804 NCBI chrNW_004624765:782,703...809,461
Ensembl chrNW_004624765:782,701...809,448 		JBrowse link
methenyltetrahydrofolate cyclohydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 enables IEA UniProt
TreeGrafter		 GO_REF:0000003 GO_REF:0000118 NCBI chrNW_004624734:36,560,486...36,620,043
Ensembl chrNW_004624734:36,560,486...36,620,026 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase enables IEA UniProt
TreeGrafter		 GO_REF:0000003 GO_REF:0000118 NCBI chrNW_004624749:29,264,577...29,276,769 JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624730:1,416,239...1,520,087
Ensembl chrNW_004624730:1,416,186...1,520,509 		JBrowse link
tRNA-specific adenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adad1 adenosine deaminase domain containing 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624777:2,812,199...2,861,179
Ensembl chrNW_004624777:2,812,383...2,859,991 		JBrowse link
G Adad2 adenosine deaminase domain containing 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624746:3,393,426...3,399,388
Ensembl chrNW_004624746:3,391,742...3,399,452 		JBrowse link
G Adar adenosine deaminase RNA specific enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624885:2,783,058...2,839,688
Ensembl chrNW_004624885:2,812,448...2,839,693 		JBrowse link
G Adarb1 adenosine deaminase RNA specific B1 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624745:30,549,195...30,635,081
Ensembl chrNW_004624745:30,549,257...30,635,269 		JBrowse link
G Adarb2 adenosine deaminase RNA specific B2 (inactive) enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624775:9,089,839...9,646,985
Ensembl chrNW_004624775:9,090,545...9,643,355 		JBrowse link
G Adat1 adenosine deaminase tRNA specific 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624746:11,356,599...11,378,183 JBrowse link
G Adat2 adenosine deaminase tRNA specific 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624753:10,826,342...10,846,199
Ensembl chrNW_004624753:10,826,297...10,846,199 		JBrowse link
G LOC101697390 adenosine deaminase domain-containing protein 1-like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624933:1,380,998...1,428,248 JBrowse link
G LOC101707801 adenosine deaminase domain-containing protein 1-like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624824:8,872,087...8,893,064 JBrowse link
tRNA-specific adenosine-34 deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adat2 adenosine deaminase tRNA specific 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624753:10,826,342...10,846,199
Ensembl chrNW_004624753:10,826,297...10,846,199 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18443
    catalytic activity 5677
      hydrolase activity 2291
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 120
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 29
            1-pyrroline-4-hydroxy-2-carboxylate deaminase activity 0
            2'-deoxyadenosine deaminase activity 1
            5'-deoxyadenosine deaminase activity 0
            5'-methylthioadenosine deaminase activity 0
            8-oxoguanine deaminase activity 0
            N-cyclopropylammelide alkylamino hydrolase activity 0
            N-cyclopropylammeline deaminase activity 0
            N-cyclopropylmelamine deaminase activity 0
            S-adenosylhomocysteine deaminase activity 0
            adenine deaminase activity 0
            adenosine deaminase activity + 13
            adenosine-phosphate deaminase activity + 3
            aminoimidazolase activity 0
            blasticidin-S deaminase activity 0
            cAMP deaminase activity 0
            creatinine deaminase activity 0
            cyclohydrolase activity + 5
            cytidine deaminase activity 6
            cytosine deaminase activity 1
            dCMP deaminase activity 2
            dCTP deaminase (dUMP-forming) activity 0
            dCTP deaminase activity 0
            diaminohydroxyphosphoribosylaminopyrimidine deaminase activity 0
            dihydropterin deaminase activity 0
            guanine deaminase activity 1
            guanosine deaminase activity 0
            isoguanine deaminase activity 0
            pterin deaminase activity 0
            pyrithiamine deaminase activity 0
            sepiapterin deaminase activity 0
paths to the root