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ONTOLOGY REPORT - ANNOTATIONS

Term:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
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Accession:GO:0016814 term browser browse the term
Definition:Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.
Synonyms:xref: EC:3.5.4


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hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase enables IEA InterPro GO_REF:0000002 NCBI chr27:37,064,107...37,073,791
Ensembl chr27:37,064,080...37,073,789 		JBrowse link
2'-deoxyadenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase enables IEA Ensembl GO_REF:0000107 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160 		JBrowse link
adenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase enables ISO
IBA
IEA 		RGD
GO_Central
UniProt
Ensembl
InterPro		 PMID:3746429 PMID:4462574 PMID:6815190 PMID:11038259 PMID:12675911 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 RGD:2291853 RGD:2291855 RGD:2291857 RGD:2291861 RGD:631747 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160 		JBrowse link
G ADA2 adenosine deaminase 2 enables IEA InterPro GO_REF:0000002 NCBI chr27:44,883,573...44,912,930
Ensembl chr27:44,884,882...44,912,850 		JBrowse link
G ADAD1 adenosine deaminase domain containing 1 enables IEA InterPro GO_REF:0000002 NCBI chr19:17,728,106...17,826,412
Ensembl chr19:17,728,281...17,826,185 		JBrowse link
G ADAD2 adenosine deaminase domain containing 2 enables IEA InterPro GO_REF:0000002 NCBI chr 5:68,163,216...68,170,044
Ensembl chr 5:68,163,170...68,170,019 		JBrowse link
G ADAL adenosine deaminase like enables IBA GO_Central GO_REF:0000033 NCBI chr30:10,191,019...10,214,089
Ensembl chr30:10,194,606...10,216,875 		JBrowse link
G ADAR adenosine deaminase RNA specific enables IEA InterPro GO_REF:0000002 NCBI chr 7:42,762,021...42,785,192
Ensembl chr 7:42,748,136...42,782,999 		JBrowse link
G ADARB1 adenosine deaminase RNA specific B1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr31:38,715,529...38,799,353
Ensembl chr31:38,678,184...38,796,521 		JBrowse link
G ADARB2 adenosine deaminase RNA specific B2 (inactive) enables IEA InterPro GO_REF:0000002 NCBI chr 2:33,510,081...33,848,968
Ensembl chr 2:33,510,961...33,847,412 		JBrowse link
G ADAT1 adenosine deaminase tRNA specific 1 enables IEA InterPro GO_REF:0000002 NCBI chr 5:75,191,114...75,235,735
Ensembl chr 5:75,190,772...75,234,480 		JBrowse link
G LACC1 laccase domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr22:6,824,942...7,002,888 JBrowse link
G LOC119876313 adenosine deaminase domain-containing protein 2-like enables IEA InterPro GO_REF:0000002
AMP deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMPD1 adenosine monophosphate deaminase 1 enables IEA
IBA 		InterPro
Ensembl
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr17:52,377,411...52,399,525
Ensembl chr17:52,377,402...52,399,520 		JBrowse link
G AMPD2 adenosine monophosphate deaminase 2 enables IEA
IBA 		InterPro
Ensembl
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:42,239,809...42,251,704
Ensembl chr 6:42,210,025...42,251,950 		JBrowse link
G AMPD3 adenosine monophosphate deaminase 3 enables ISO
IBA
IEA 		RGD
GO_Central
InterPro		 PMID:9291127 GO_REF:0000002 GO_REF:0000033 RGD:632203
cytidine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase enables ISS
IEA
IBA 		UniProt
Ensembl
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr27:37,064,107...37,073,791
Ensembl chr27:37,064,080...37,073,789 		JBrowse link
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 enables ISO
IBA 		RGD
GO_Central		 PMID:8511591 GO_REF:0000033 RGD:634661 NCBI chr27:37,102,728...37,114,084
Ensembl chr27:37,103,016...37,114,556 		JBrowse link
G APOBEC2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 enables IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:9,808,276...9,819,973
Ensembl chr12:9,808,297...9,819,985 		JBrowse link
G APOBEC3Z1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z1 enables IBA GO_Central GO_REF:0000033
G APOBEC3Z3 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z3 enables IBA GO_Central GO_REF:0000033 NCBI chr10:25,910,973...25,917,508
Ensembl chr10:25,911,291...25,913,808 		JBrowse link
G CDA cytidine deaminase enables IEA
IBA 		InterPro
GO_Central
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr 2:78,305,328...78,327,229
Ensembl chr 2:78,304,726...78,327,247 		JBrowse link
G CDADC1 cytidine and dCMP deaminase domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr22:2,443,459...2,489,147
Ensembl chr22:2,436,206...2,489,016 		JBrowse link
cytosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 ISO RGD PMID:12697753 RGD:1358271 NCBI chr27:37,102,728...37,114,084
Ensembl chr27:37,103,016...37,114,556 		JBrowse link
dCMP deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDADC1 cytidine and dCMP deaminase domain containing 1 enables IBA GO_Central GO_REF:0000033 NCBI chr22:2,443,459...2,489,147
Ensembl chr22:2,436,206...2,489,016 		JBrowse link
G DCTD dCMP deaminase enables IEA
IBA 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr16:47,350,493...47,376,184
Ensembl chr16:47,350,357...47,375,127
Ensembl chr16:47,350,357...47,375,127 		JBrowse link
GTP cyclohydrolase I activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCH1 GTP cyclohydrolase 1 NOT|enables ISO
IBA
IEA 		(PMID:11284739), (PMID:8068008) UniProt
GO_Central
UniProt
RGD
Ensembl
InterPro		 PMID:2557335 PMID:8068008 PMID:8486153 PMID:8702680 PMID:9636709 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 RGD:1601284 RGD:2298653 RGD:2298654 RGD:2298655 RGD:728623 NCBI chr 8:30,733,422...30,784,067
Ensembl chr 8:30,732,608...30,784,156 		JBrowse link
guanine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDA guanine deaminase enables ISO
IBA
IEA 		RGD
GO_Central
Ensembl
UniProt
InterPro		 PMID:11784697 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 RGD:708341 NCBI chr 1:85,506,598...85,586,212
Ensembl chr 1:85,444,917...85,586,163 		JBrowse link
IMP cyclohydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase enables ISO
IBA
IEA 		RGD
GO_Central
InterPro		 PMID:9332377 GO_REF:0000002 GO_REF:0000033 RGD:70804 NCBI chr37:22,420,645...22,446,769
Ensembl chr37:22,420,603...22,446,697 		JBrowse link
methenyltetrahydrofolate cyclohydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 enables IBA GO_Central GO_REF:0000033 NCBI chr 8:38,831,672...38,889,607
Ensembl chr 8:38,831,860...38,889,453 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase enables IBA GO_Central GO_REF:0000033 NCBI chr17:48,882,838...48,896,816
Ensembl chr17:48,883,724...48,941,949 		JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like enables IBA GO_Central GO_REF:0000033 NCBI chr13:62,670,543...62,803,270
Ensembl chr13:62,670,462...62,803,519 		JBrowse link
tRNA-specific adenosine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAD1 adenosine deaminase domain containing 1 enables IBA GO_Central GO_REF:0000033 NCBI chr19:17,728,106...17,826,412
Ensembl chr19:17,728,281...17,826,185 		JBrowse link
G ADAR adenosine deaminase RNA specific enables IBA GO_Central GO_REF:0000033 NCBI chr 7:42,762,021...42,785,192
Ensembl chr 7:42,748,136...42,782,999 		JBrowse link
G ADARB1 adenosine deaminase RNA specific B1 enables IBA GO_Central GO_REF:0000033 NCBI chr31:38,715,529...38,799,353
Ensembl chr31:38,678,184...38,796,521 		JBrowse link
G ADARB2 adenosine deaminase RNA specific B2 (inactive) enables IBA GO_Central GO_REF:0000033 NCBI chr 2:33,510,081...33,848,968
Ensembl chr 2:33,510,961...33,847,412 		JBrowse link
G ADAT1 adenosine deaminase tRNA specific 1 enables IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:75,191,114...75,235,735
Ensembl chr 5:75,190,772...75,234,480 		JBrowse link
G ADAT2 adenosine deaminase tRNA specific 2 enables IEA InterPro GO_REF:0000002 NCBI chr 1:34,953,737...34,993,969
Ensembl chr 1:34,965,778...34,994,285 		JBrowse link
G LOC119876313 adenosine deaminase domain-containing protein 2-like enables IBA GO_Central GO_REF:0000033
tRNA-specific adenosine-34 deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAT2 adenosine deaminase tRNA specific 2 enables IBA GO_Central GO_REF:0000033 NCBI chr 1:34,953,737...34,993,969
Ensembl chr 1:34,965,778...34,994,285 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21956
    catalytic activity 5783
      hydrolase activity 2416
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 128
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 29
            1-pyrroline-4-hydroxy-2-carboxylate deaminase activity 0
            2'-deoxyadenosine deaminase activity 1
            5'-deoxyadenosine deaminase activity 0
            5'-methylthioadenosine deaminase activity 0
            8-oxoguanine deaminase activity 0
            N-cyclopropylammelide alkylamino hydrolase activity 0
            N-cyclopropylammeline deaminase activity 0
            N-cyclopropylmelamine deaminase activity 0
            S-adenosylhomocysteine deaminase activity 0
            adenine deaminase activity 0
            adenosine deaminase activity + 12
            adenosine-phosphate deaminase activity + 3
            aminoimidazolase activity 0
            blasticidin-S deaminase activity 0
            cAMP deaminase activity 0
            creatinine deaminase activity 0
            cyclohydrolase activity + 5
            cytidine deaminase activity 7
            cytosine deaminase activity 1
            dCMP deaminase activity 2
            dCTP deaminase (dUMP-forming) activity 0
            dCTP deaminase activity 0
            diaminohydroxyphosphoribosylaminopyrimidine deaminase activity 0
            dihydropterin deaminase activity 0
            guanine deaminase activity 1
            guanosine deaminase activity 0
            isoguanine deaminase activity 0
            pterin deaminase activity 0
            pyrithiamine deaminase activity 0
            sepiapterin deaminase activity 0
paths to the root