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ONTOLOGY REPORT - ANNOTATIONS

Term:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
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Accession:GO:0016813 term browser browse the term
Definition:Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
Synonyms:xref: EC:3.5.3


show annotations for term's descendants           Sort by:
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 5:159,326,680...159,357,300
Ensembl chr 5:154,060,151...154,074,276 		JBrowse link
G Arg1 arginase 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arg2 arginase 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
agmatinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase enables IBA
IEA		 GO_REF:0000033
GO_REF:0000003		 GO_Central
UniProt		 GO_REF:0000003 GO_REF:0000033 NCBI chr 5:159,326,680...159,357,300
Ensembl chr 5:154,060,151...154,074,276 		JBrowse link
allantoicase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Allc allantoicase enables IEA GO_REF:0000003
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr 6:45,179,181...45,214,275
Ensembl chr 6:45,179,187...45,214,223 		JBrowse link
arginase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000116
(PMID:36543883)		 UniProt
Ensembl
RHEA
RGD		 PMID:36543883 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr 5:159,326,680...159,357,300
Ensembl chr 5:154,060,151...154,074,276 		JBrowse link
G Arg1 arginase 1 enables IDA
IEA
ISO
IBA		 GO_REF:0000002
GO_REF:0000116
GO_REF:0000003
GO_REF:0000107
(PMID:9502196)
GO_REF:0000033		 InterPro
RHEA
UniProt
Ensembl
RGD
GO_Central		 PMID:9502196 PMID:12069499 PMID:4062872 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116, RGD:634666, RGD:2300098 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arg2 arginase 2 enables IDA
IEA
IBA
ISO		 GO_REF:0000116
GO_REF:0000107
GO_REF:0000033
GO_REF:0000002
PMID:16537391
GO_REF:0000003
(PMID:16128822)		 RHEA
Ensembl
GO_Central
InterPro
UniProt
RGD		 PMID:16128822 PMID:11829529 PMID:16537391 PMID:16537391 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116, RGD:634667, RGD:1582129, RGD:1582129 NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
dimethylargininase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddah1 dimethylarginine dimethylaminohydrolase 1 enables TAS
IEA
ISO
IBA
ISS
IDA		 GO_REF:0000116
GO_REF:0000107
GO_REF:0000003
MGI:5424370 (PMID:21493890), (PMID:37296100)
GO_REF:0000033
(PMID:19663506), (PMID:37296100)
GO_REF:0000024		 RHEA
Ensembl
UniProt
RGD
GO_Central		 PMID:19663506 PMID:21493890 PMID:37296100 PMID:9003431 PMID:17322279 More... GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116, RGD:70711, RGD:1625578, RGD:727432 NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Ddah2 DDAH family member 2, ADMA-independent NOT|enables ISO UniProtKB:O94760 (PMID:21493890), (PMID:37296100)
MGI:3530071 (PMID:37296100)		 RGD PMID:21493890 PMID:37296100 NCBI chr20:3,766,115...3,769,161
Ensembl chr20:3,761,465...3,764,511 		JBrowse link
guanidinobutyrase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000116
(PMID:36543883)		 UniProt
Ensembl
RHEA
RGD		 PMID:36543883 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr 5:159,326,680...159,357,300
Ensembl chr 5:154,060,151...154,074,276 		JBrowse link
guanidinopropionase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000116
(PMID:36543883)		 UniProt
Ensembl
RHEA
RGD		 PMID:36543883 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr 5:159,326,680...159,357,300
Ensembl chr 5:154,060,151...154,074,276 		JBrowse link
histone arginine deiminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Padi2 peptidyl arginine deiminase 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:158,492,087...158,534,662
Ensembl chr 5:153,209,053...153,251,632 		JBrowse link
G Padi4 peptidyl arginine deiminase 4 enables ISO
IBA		 (PMID:16567635)
GO_REF:0000033		 RGD
GO_Central		 PMID:16567635 GO_REF:0000033 NCBI chr 5:158,324,417...158,357,466
Ensembl chr 5:153,041,352...153,074,362 		JBrowse link
histone H3R17 arginine deiminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Padi4 peptidyl arginine deiminase 4 enables ISO (PMID:15339660), (PMID:15345777) RGD PMID:15339660 PMID:15345777 NCBI chr 5:158,324,417...158,357,466
Ensembl chr 5:153,041,352...153,074,362 		JBrowse link
histone H3R2 arginine deiminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Padi4 peptidyl arginine deiminase 4 enables ISO (PMID:15339660), (PMID:15345777) RGD PMID:15339660 PMID:15345777 NCBI chr 5:158,324,417...158,357,466
Ensembl chr 5:153,041,352...153,074,362 		JBrowse link
histone H3R26 arginine deiminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Padi2 peptidyl arginine deiminase 2 enables ISO (PMID:22853951) RGD PMID:22853951 NCBI chr 5:158,492,087...158,534,662
Ensembl chr 5:153,209,053...153,251,632 		JBrowse link
G Padi4 peptidyl arginine deiminase 4 enables ISO (PMID:15339660), (PMID:15345777) RGD PMID:15339660 PMID:15345777 NCBI chr 5:158,324,417...158,357,466
Ensembl chr 5:153,041,352...153,074,362 		JBrowse link
histone H3R8 arginine deiminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Padi4 peptidyl arginine deiminase 4 enables ISO (PMID:15339660), (PMID:15345777) RGD PMID:15339660 PMID:15345777 NCBI chr 5:158,324,417...158,357,466
Ensembl chr 5:153,041,352...153,074,362 		JBrowse link
protein-arginine deiminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Padi1 peptidyl arginine deiminase 1 enables IDA
IEA
IBA
ISO		 GO_REF:0000104
GO_REF:0000116
GO_REF:0000107
GO_REF:0000003
GO_REF:0000033
GO_REF:0000002
PMID:12392711
(PMID:27393304)		 UniProt
RHEA
Ensembl
GO_Central
InterPro
RGD		 PMID:27393304 PMID:9738944 PMID:12392711 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116, RGD:69924, RGD:8554540 NCBI chr 5:153,119,566...153,152,034
Ensembl chr 5:153,119,566...153,152,034 		JBrowse link
G Padi2 peptidyl arginine deiminase 2 enables IDA
IEA
ISO		 PMID:12392711
GO_REF:0000002
GO_REF:0000003
GO_REF:0000116
GO_REF:0000104
(PMID:12392711), (PMID:15629448), (PMID:18645041), (PMID:25621824)		 InterPro
UniProt
RHEA
RGD		 PMID:12392711 PMID:15629448 PMID:18645041 PMID:25621824 PMID:12392711 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000116, RGD:8554540 NCBI chr 5:158,492,087...158,534,662
Ensembl chr 5:153,209,053...153,251,632 		JBrowse link
G Padi3 peptidyl arginine deiminase 3 enables IDA
IEA
IBA
ISO		 GO_REF:0000116
GO_REF:0000104
GO_REF:0000003
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033
(PMID:27866708)
PMID:12392711		 RHEA
UniProt
InterPro
Ensembl
GO_Central
RGD		 PMID:27866708 PMID:9192727 PMID:12392711 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116, RGD:69926, RGD:8554540 NCBI chr 5:158,372,764...158,400,193
Ensembl chr 5:153,089,717...153,117,146 		JBrowse link
G Padi4 peptidyl arginine deiminase 4 enables IDA
IEA
ISO		 GO_REF:0000116
GO_REF:0000003
(PMID:24463520)
GO_REF:0000002
(PMID:15247907), (PMID:15629448), (PMID:21584310)
PMID:12392711		 RHEA
UniProt
RGD
InterPro		 PMID:15247907 PMID:15629448 PMID:21584310 PMID:24463520 PMID:9738944 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000116, RGD:69924, RGD:8554540 NCBI chr 5:158,324,417...158,357,466
Ensembl chr 5:153,041,352...153,074,362 		JBrowse link
G Padi6 peptidyl arginine deiminase 6 NOT|contributes_to
NOT|enables		 ISO
IBA		 (PMID:38656308), (PMID:39286527)
GO_REF:0000033		 RGD
GO_Central		 PMID:38656308 PMID:39286527 GO_REF:0000033 NCBI chr 5:153,021,855...153,037,443
Ensembl chr 5:153,021,965...153,037,414 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21102
    catalytic activity 7309
      hydrolase activity 3455
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 128
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 11
            2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity 0
            5-ureido-4-imidazole carboxylate hydrolase activity 0
            D-arginase activity 0
            N-succinylarginine dihydrolase activity 0
            agmatinase activity 1
            agmatine deiminase activity 0
            allantoate deiminase activity 0
            allantoicase activity 1
            amidinoaspartase activity 0
            aminopropylagmatine ureohydrolase activity 0
            ammelide aminohydrolase activity 0
            ammeline aminohydrolase activity 0
            arginase activity 3
            arginine deiminase activity 0
            creatinase activity 0
            deisopropylhydroxyatrazine aminohydrolase activity 0
            diguanidinobutanase activity 0
            dimethylargininase activity 2
            formimidoylaspartate deiminase activity 0
            formimidoylglutamase activity 0
            formimidoylglutamate deiminase activity 0
            guanidinoacetase activity 0
            guanidinobutyrase activity 1
            guanidinopropionase activity 1
            methylenediurea deaminase activity 0
            methylguanidinase activity 0
            proclavaminate amidinohydrolase activity 0
            protein-arginine deiminase activity + 5
            ureidoglycine aminohydrolase activity 0
paths to the root