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ONTOLOGY REPORT - ANNOTATIONS

Term:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
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Accession:GO:0016812 term browser browse the term
Definition:Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide.
Synonyms:xref: EC:3.5.2;   Reactome:R-HSA-70906 "4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+"


show annotations for term's descendants           Sort by:
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd1 amidohydrolase domain containing 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156 		JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Crmp1 collapsin response mediator protein 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157 		JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914 		JBrowse link
G Dpysl5 dihydropyrimidinase-like 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:25,575,104...25,659,422
Ensembl chr 6:25,575,104...25,659,422 		JBrowse link
5-oxoprolinase (ATP-hydrolyzing) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oplah 5-oxoprolinase (ATP-hydrolysing) enables ISS
IBA
IEA		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000003
GO_REF:0000116		 UniProt
GO_Central
RHEA		 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 NCBI chr 7:108,011,472...108,051,751
Ensembl chr 7:108,011,475...108,035,297 		JBrowse link
beta-lactamase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dclre1a DNA cross-link repair 1A enables ISO
IEA		 (PMID:31434986)
GO_REF:0000107		 RGD
Ensembl		 PMID:31434986 GO_REF:0000107 NCBI chr 1:255,569,911...255,589,815
Ensembl chr 1:255,569,919...255,589,678 		JBrowse link
G Dclre1b DNA cross-link repair 1B enables ISO
IEA
ISS		 (PMID:31434986)
GO_REF:0000116
GO_REF:0000024
GO_REF:0000107		 RGD
RHEA
UniProt
Ensembl		 PMID:31434986 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423 		JBrowse link
G Dpep1 dipeptidase 1 enables ISO
IEA
ISS		 (PMID:32325220), (PMID:6334084)
GO_REF:0000003
GO_REF:0000116
GO_REF:0000107
(PMID:12738806)
GO_REF:0000024		 RGD
UniProt
RHEA
Ensembl		 PMID:6334084 PMID:12738806 PMID:32325220 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257 		JBrowse link
G Mblac2 metallo-beta-lactamase domain containing 2 enables ISO
IEA		 (PMID:31434986)
GO_REF:0000107		 RGD
Ensembl		 PMID:31434986 GO_REF:0000107 NCBI chr 2:11,986,075...12,028,882
Ensembl chr 2:11,986,027...12,030,950 		JBrowse link
dihydroorotase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase enables IDA
IEA
ISO
IBA		 GO_REF:0000107
GO_REF:0000003
(PMID:33771897)
GO_REF:0000033
(PMID:24332717)		 Ensembl
UniProt
RGD
GO_Central		 PMID:24332717 PMID:33771897 PMID:1148171 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107, RGD:2303536 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Dhodh dihydroorotate dehydrogenase enables ISO (PMID:20413687), (PMID:33771897) RGD PMID:20413687 PMID:33771897 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654 		JBrowse link
dihydropyrimidinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crmp1 collapsin response mediator protein 1 NOT|enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177 		JBrowse link
G Dpys dihydropyrimidinase enables IDA
IEA
ISO
IBA		 GO_REF:0000003
GO_REF:0000116
(PMID:5472365)
GO_REF:0000033
GO_REF:0000107
(PMID:10410956), (PMID:18075467), (PMID:9718352)
PMID:8307005		 UniProt
RHEA
RGD
GO_Central
Ensembl		 PMID:5472365 PMID:9718352 PMID:10410956 PMID:18075467 PMID:7626590 More... GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116, RGD:1624989, RGD:1624990, RGD:1624990 NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 NOT|enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 NOT|enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157 		JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 NOT|enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914 		JBrowse link
G Dpysl5 dihydropyrimidinase-like 5 NOT|enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:25,575,104...25,659,422
Ensembl chr 6:25,575,104...25,659,422 		JBrowse link
hydroxyisourate hydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Urah urate (5-hydroxyiso-) hydrolase enables IEA GO_REF:0000003
GO_REF:0000002
GO_REF:0000107		 UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 NCBI chr 1:195,905,763...195,909,159
Ensembl chr 1:195,905,763...195,909,159 		JBrowse link
imidazolonepropionase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd1 amidohydrolase domain containing 1 enables IBA
IEA		 GO_REF:0000033
GO_REF:0000003		 GO_Central
UniProt		 GO_REF:0000003 GO_REF:0000033 NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21100
    catalytic activity 6213
      hydrolase activity 2621
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 127
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 15
            2,5-dioxopiperazine hydrolase activity 0
            5-oxoprolinase (ATP-hydrolyzing) activity 1
            6-aminohexanoate-cyclic-dimer hydrolase activity 0
            L-lysine-lactamase activity 0
            N-methylhydantoinase (ATP-hydrolyzing) activity 0
            allantoinase activity 0
            barbiturase activity 0
            beta-lactamase activity 4
            carboxymethylhydantoinase activity 0
            creatininase activity 0
            cyanuric acid amidohydrolase activity 0
            dihydroorotase activity 2
            dihydropyrimidinase activity 6
            enamidase activity 0
            epsilon-caprolactam lactamase activity 0
            hydroxyisourate hydrolase activity 1
            imidazolone hydrolase activity 0
            imidazolonepropionase activity 1
            maleimide hydrolase activity 0
            xanthine hydrolase activity 0
paths to the root