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ONTOLOGY REPORT - ANNOTATIONS

Term:oxidoreductase activity, acting on metal ions
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Accession:GO:0016722 term browser browse the term
Definition:Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered.
Synonyms:related_synonym: oxidoreductase activity, oxidizing metal ions;   oxidoreductase activity, reducing metal ions
 xref: EC:1.16;   reactome:R-HSA-917805 "CYBRD1:Heme reduces Fe3+ to Fe2+"


show annotations for term's descendants           Sort by:
oxidoreductase activity, acting on metal ions term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cybrd1 cytochrome b reductase 1 enables ISO
IEA		 (PMID:14499595)
GO_REF:0000107		 RGD
Ensembl		 PMID:14499595 GO_REF:0000107 NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108 		JBrowse link
G Frrs1 ferric-chelate reductase 1 enables IBA
ISO		 GO_REF:0000033
(PMID:14499595)		 GO_Central
RGD		 PMID:14499595 GO_REF:0000033 NCBI chr 2:204,820,898...204,881,487
Ensembl chr 2:204,823,025...204,895,540 		JBrowse link
[methionine synthase] reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase enables ISO
IEA
IBA		 (PMID:11466310), (PMID:9501215)
GO_REF:0000003
GO_REF:0000116
(PMID:17369066)
GO_REF:0000033		 RGD
UniProt
RHEA
GO_Central		 PMID:9501215 PMID:11466310 PMID:17369066 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr 1:36,695,376...36,727,341
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
cupric reductase (NADH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Steap1 STEAP family member 1 NOT|enables ISO (PMID:16609065) RGD PMID:16609065 NCBI chr 4:29,231,809...29,242,317
Ensembl chr 4:28,276,909...28,287,479 		JBrowse link
G Steap2 STEAP2 metalloreductase enables IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:16609065)		 GO_Central
Ensembl
RGD		 PMID:16609065 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:29,302,487...29,323,006
Ensembl chr 4:28,348,362...28,375,791 		JBrowse link
G Steap3 STEAP3 metalloreductase enables IBA
ISO		 GO_REF:0000033
(PMID:16609065)		 GO_Central
RGD		 PMID:16609065 GO_REF:0000033 NCBI chr13:33,904,710...33,950,100
Ensembl chr13:31,351,954...31,396,519 		JBrowse link
G Steap4 STEAP4 metalloreductase enables IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:16609065)		 GO_Central
Ensembl
RGD		 PMID:16609065 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:27,032,096...27,054,769
Ensembl chr 4:26,054,671...26,099,859 		JBrowse link
cyanocobalamin reductase (cyanide-eliminating) (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmachc metabolism of cobalamin associated C enables ISO
IEA
IBA		 (PMID:19700356)
GO_REF:0000003
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:19700356 GO_REF:0000003 GO_REF:0000033 NCBI chr 5:130,166,056...130,172,735
Ensembl chr 5:130,166,451...130,172,601 		JBrowse link
ferric-chelate reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Steap1 STEAP family member 1 NOT|enables ISO (PMID:32409586)
(PMID:16609065)		 RGD PMID:16609065 PMID:32409586 NCBI chr 4:29,231,809...29,242,317
Ensembl chr 4:28,276,909...28,287,479 		JBrowse link
G Steap2 STEAP2 metalloreductase enables IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:16609065)		 GO_Central
Ensembl
RGD		 PMID:16609065 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:29,302,487...29,323,006
Ensembl chr 4:28,348,362...28,375,791 		JBrowse link
G Steap3 STEAP3 metalloreductase enables ISO
IBA
ISS		 (PMID:26205815)
MGI:3758911 (PMID:16609065), (PMID:18955558)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:16609065 PMID:18955558 PMID:26205815 GO_REF:0000024 GO_REF:0000033 NCBI chr13:33,904,710...33,950,100
Ensembl chr13:31,351,954...31,396,519 		JBrowse link
G Steap4 STEAP4 metalloreductase enables ISO
IEA
IBA		 (PMID:30337524)
GO_REF:0000003
GO_REF:0000107
(PMID:16609065)
GO_REF:0000033		 RGD
UniProt
Ensembl
GO_Central		 PMID:16609065 PMID:30337524 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:27,032,096...27,054,769
Ensembl chr 4:26,054,671...26,099,859 		JBrowse link
ferric-chelate reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Steap3 STEAP3 metalloreductase enables ISO (PMID:16227996) RGD PMID:16227996 NCBI chr13:33,904,710...33,950,100
Ensembl chr13:31,351,954...31,396,519 		JBrowse link
ferroxidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cp ceruloplasmin enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000003
GO_REF:0000116
(PMID:16436657)
(PMID:14623105), (PMID:16150804), (PMID:29183916)		 UniProt
RHEA
RGD		 PMID:14623105 PMID:16150804 PMID:16436657 PMID:29183916 GO_REF:0000003 GO_REF:0000024 GO_REF:0000116 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Fth1 ferritin heavy chain 1 enables ISO
IEA		 (PMID:9003196)
GO_REF:0000003
GO_REF:0000116		 RGD
UniProt
RHEA		 PMID:9003196 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Ftmt ferritin mitochondrial enables ISO
IEA		 (PMID:11323407), (PMID:15201052)
GO_REF:0000107
(PMID:15201052)		 RGD
Ensembl		 PMID:11323407 PMID:15201052 GO_REF:0000107 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123 		JBrowse link
G Fxn frataxin enables ISO
IEA
IBA		 (PMID:15641778)
GO_REF:0000116
GO_REF:0000003
GO_REF:0000002
GO_REF:0000033		 RGD
RHEA
UniProt
InterPro
GO_Central		 PMID:15641778 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Heph hephaestin enables ISO
IEA
IBA
ISS		 (PMID:22961397)
GO_REF:0000107
GO_REF:0000116
GO_REF:0000033
(PMID:14751926)
GO_REF:0000024		 RGD
Ensembl
RHEA
GO_Central
UniProt		 PMID:14751926 PMID:22961397 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 NCBI chr  X:65,160,628...65,412,457
Ensembl chr  X:61,296,345...61,402,980 		JBrowse link
G Hephl1 hephaestin-like 1 enables ISO
IEA
IBA		 (PMID:20685892), (PMID:31125343)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:20685892 PMID:31125343 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:11,896,768...11,965,282
Ensembl chr 8:11,898,532...11,965,267 		JBrowse link
oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase enables ISS
ISO		 GO_REF:0000024
(PMID:17892308)		 UniProt
RGD		 PMID:17892308 GO_REF:0000024 NCBI chr 1:36,695,376...36,727,341
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
G Steap1 STEAP family member 1 NOT|enables ISO (PMID:16609065) RGD PMID:16609065 NCBI chr 4:29,231,809...29,242,317
Ensembl chr 4:28,276,909...28,287,479 		JBrowse link
oxidoreductase activity, acting on metal ions, oxygen as acceptor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cp ceruloplasmin enables ISS
ISO		 GO_REF:0000024
(PMID:14623105)		 UniProt
RGD		 PMID:14623105 GO_REF:0000024 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
transmembrane ascorbate ferrireductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyb561a3 cytochrome b561 family, member A3 enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000116
GO_REF:0000107
GO_REF:0000003
(PMID:16911521)		 UniProt
RHEA
Ensembl
RGD		 PMID:16911521 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr 1:207,216,185...207,237,575
Ensembl chr 1:207,226,230...207,237,571 		JBrowse link
G Cyb561d2 cytochrome b561 family, member D2 enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:17938141)
GO_REF:0000116
GO_REF:0000003
GO_REF:0000107		 UniProt
RGD
RHEA
Ensembl		 PMID:17938141 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr 8:108,213,201...108,215,778
Ensembl chr 8:108,213,205...108,215,759 		JBrowse link
G Cybrd1 cytochrome b reductase 1 enables ISO
IEA
ISS		 (PMID:17068337), (PMID:30272000)
GO_REF:0000003
GO_REF:0000116
GO_REF:0000107
GO_REF:0000024		 RGD
UniProt
RHEA
Ensembl		 PMID:17068337 PMID:30272000 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21100
    catalytic activity 6213
      oxidoreductase activity 868
        oxidoreductase activity, acting on metal ions 16
          ferric-chelate reductase activity + 4
          oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor + 6
          oxidoreductase activity, acting on metal ions, oxygen as acceptor + 6
          transmembrane ascorbate ferrireductase activity 3
paths to the root