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ONTOLOGY REPORT - ANNOTATIONS

Term:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
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Accession:GO:0016655 term browser browse the term
Definition:Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
Synonyms:related_synonym: oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
 xref: EC:1.6.5


show annotations for term's descendants           Sort by:
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm2 AIF family member 2 enables ISO (PMID:31634899), (PMID:31634900), (PMID:35922516) RGD PMID:31634899 PMID:31634900 PMID:35922516 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 enables ISO (PMID:19442656), (PMID:20837989) RGD PMID:19442656 PMID:20837989 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 enables ISO (PMID:20837989) RGD PMID:20837989 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 enables ISO (PMID:19442656), (PMID:20837989) RGD PMID:19442656 PMID:20837989 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Cbr1 carbonyl reductase 1 enables ISO (PMID:19442656) RGD PMID:19442656 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase enables ISO (PMID:19442656) RGD PMID:19442656 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Dhrs4 dehydrogenase/reductase 4 enables ISO (PMID:19442656) RGD PMID:19442656 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127 		JBrowse link
NAD(P)H dehydrogenase (quinone) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07044714.1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr20:16,974,380...16,975,074 JBrowse link
G Cbr4 carbonyl reductase 4 enables ISO (PMID:20837989) RGD PMID:20837989 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 enables IDA
IBA
ISO		 GO_REF:0000033
(PMID:15386390), (PMID:16190898), (PMID:1914521)		 GO_Central
RGD		 PMID:1914521 PMID:15386390 PMID:16190898 PMID:12603827 GO_REF:0000033, RGD:727509 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
NADH dehydrogenase (ubiquinone) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 enables ISO
ISS		 (PMID:1959619)
GO_REF:0000024		 RGD
UniProt		 PMID:1959619 GO_REF:0000024 NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694 		JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 enables ISO
IBA
ISS		 (PMID:16996290)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:16996290 GO_REF:0000024 GO_REF:0000033 NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942 		JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 enables ISO
IBA
ISS		 (PMID:25118196)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:25118196 GO_REF:0000024 GO_REF:0000033 NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798 		JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 enables ISO
ISS		 (PMID:15250827), (PMID:8344246), (PMID:8644732)
GO_REF:0000024		 RGD
UniProt		 PMID:8344246 PMID:8644732 PMID:15250827 GO_REF:0000024 NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537 		JBrowse link
G Mt-nd4l mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L enables ISS
ISO		 GO_REF:0000024
(PMID:28844695), (PMID:29915388)		 UniProt
RGD		 PMID:28844695 PMID:29915388 GO_REF:0000024 NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166 		JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 enables
contributes_to		 ISO
ISS		 (PMID:15250827)
(PMID:18729827)
GO_REF:0000024		 RGD
UniProt		 PMID:15250827 PMID:18729827 GO_REF:0000024 NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565 		JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 enables ISS
ISO		 GO_REF:0000024
(PMID:9707444)
(PMID:14595656), (PMID:8644732)		 UniProt
RGD		 PMID:8644732 PMID:9707444 PMID:14595656 GO_REF:0000024 NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061 		JBrowse link
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 enables ISO (PMID:24652937) RGD PMID:24652937 NCBI chr 9:93,007,034...93,041,825
Ensembl chr 9:93,007,042...93,042,560 		JBrowse link
G Ndufb7 NADH:ubiquinone oxidoreductase subunit B7 enables ISO (PMID:33502047) RGD PMID:33502047 NCBI chr19:24,568,241...24,572,579
Ensembl chr19:24,568,241...24,572,579 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 contributes_to
enables		 ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(PMID:27799543), (PMID:32072193)
GO_REF:0000002
(PMID:30879903), (PMID:31557978)
(PMID:15824269), (PMID:16478720), (PMID:16870178)		 UniProt
GO_Central
RGD
InterPro		 PMID:15824269 PMID:16478720 PMID:16870178 PMID:27799543 PMID:30879903 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893 		JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 contributes_to
enables		 ISO
ISS
IMP		 (PMID:22036843), (PMID:30922174)
(PMID:26437605), (PMID:29887397), (PMID:31297047)
GO_REF:0000024
(PMID:28031252)		 RGD
UniProt		 PMID:22036843 PMID:26437605 PMID:28031252 PMID:29887397 PMID:30922174 More... GO_REF:0000024, RGD:42722001 NCBI chr13:83,654,402...83,671,474
Ensembl chr13:83,654,406...83,671,420 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 contributes_to
enables		 ISO (PMID:30140060)
(PMID:31916679), (PMID:33148885)
(PMID:14729820)		 RGD PMID:14729820 PMID:30140060 PMID:31916679 PMID:33148885 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 contributes_to
enables		 ISO
IEA		 (PMID:15038602), (PMID:16870178)
MGI:3527173|MGI:3793713 (PMID:10747996), (PMID:18396137), (PMID:26712463), (PMID:29501746)
GO_REF:0000107
(PMID:16478720)		 RGD
Ensembl		 PMID:10747996 PMID:15038602 PMID:16478720 PMID:16870178 PMID:18396137 More... GO_REF:0000107 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846 		JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 enables ISO
IBA		 (PMID:17275378)
GO_REF:0000033		 RGD
GO_Central		 PMID:17275378 GO_REF:0000033 NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 contributes_to
enables		 ISO (PMID:9837812)
(PMID:22499348)		 RGD PMID:9837812 PMID:22499348 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511 		JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 enables ISO (PMID:28844695)
(PMID:29915388)		 RGD PMID:28844695 PMID:29915388 NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 contributes_to
enables		 ISO
IEA
ISS		 (PMID:12754703)
(PMID:29915388)
(PMID:28844695)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12754703 PMID:28844695 PMID:29915388 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713 		JBrowse link
NADH:ubiquinone reductase (non-electrogenic) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nqo1 NAD(P)H quinone dehydrogenase 1 enables IDA
ISO		 PMID:8999809
(PMID:8999809), (PMID:9271353)		 RGD PMID:8999809 PMID:9271353 PMID:8999809 RGD:151356617 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
NADPH dehydrogenase (quinone) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr3 carbonyl reductase 3 enables ISS
ISO		 GO_REF:0000024
(PMID:19841672)		 UniProt
RGD		 PMID:19841672 GO_REF:0000024 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Cbr4 carbonyl reductase 4 enables ISO
IEA
ISS		 (PMID:19000905)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19000905 GO_REF:0000024 GO_REF:0000107 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Rtn4ip1 reticulon 4 interacting protein 1 enables ISO (PMID:37884807) RGD PMID:37884807 NCBI chr20:47,382,251...47,422,747
Ensembl chr20:47,382,234...47,422,338 		JBrowse link
NADPH:quinone reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide enables ISO (PMID:10514444) RGD PMID:10514444 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Cryz crystallin zeta enables ISO
IBA
IEA
ISS		 (PMID:17497241)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:17497241 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 enables ISO (PMID:19349281) RGD PMID:19349281 NCBI chr 6:27,818,327...27,825,753 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21087
    catalytic activity 6127
      oxidoreductase activity 868
        oxidoreductase activity, acting on NAD(P)H 65
          oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 33
            2-hydroxy-1,4-benzoquinone reductase activity 0
            NAD(P)H dehydrogenase (quinone) activity + 6
            NADH dehydrogenase (ubiquinone) activity 17
            NADH:menaquinone oxidoreductase activity 0
            NADH:ubiquinone reductase (non-electrogenic) activity 1
            NADPH:quinone reductase activity 3
            monodehydroascorbate reductase (NADH) activity 0
            p-benzoquinone reductase (NADPH) activity 0
paths to the root