Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
go back to main search page
Accession:GO:0016628 term browser browse the term
Definition:Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.
Synonyms:xref: EC:1.3.1;   Reactome:R-HSA-4755572 "Defective SRD5A3 does not reduce pPNOL to DCHOL";   Reactome:R-HSA-9661726 "An unknown reductase reduces D-UBGN to STBN";   Reactome:R-HSA-9661745 "An unknown BILR reduces BIL to D-UBGN";   reactome:R-HSA-4419979 "SRD5A3 reduces pPNOL to DCHOL"


show annotations for term's descendants           Sort by:
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07021955.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G Bdh2 3-hydroxybutyrate dehydrogenase 2 enables ISS
ISO 		GO_REF:0000024
(PMID:20550936) 		UniProt
RGD		 PMID:20550936 GO_REF:0000024 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase enables ISO
IEA 		(PMID:11519011)
GO_REF:0000107 		RGD
Ensembl		 PMID:11519011 GO_REF:0000107 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Lbr lamin B receptor enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:93,539,386...93,564,026
Ensembl chr13:93,538,920...93,564,017 		JBrowse link
G Ptgr1 prostaglandin reductase 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
G Ptgr2 prostaglandin reductase 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111 		JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
GO_REF:0000104
(PMID:20637498) 		UniProt
Ensembl
RGD		 PMID:20637498 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270 		JBrowse link
12-hydroxyheptadecatrienoic acid synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbxas1 thromboxane A synthase 1 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 4:68,631,841...68,803,959
Ensembl chr 4:67,665,007...67,837,096 		JBrowse link
15-oxoprostaglandin 13-oxidase [NAD(P)+] activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgr1 prostaglandin reductase 1 enables IDA
IEA
IBA
ISO 		PMID:11524419
GO_REF:0000002
GO_REF:0000116
GO_REF:0000003
GO_REF:0000033
(PMID:11688989)
(PMID:25619643)
GO_REF:0000107 		InterPro
RHEA
UniProt
GO_Central
RGD
Ensembl		 PMID:11688989 PMID:25619643 PMID:11524419 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116, RGD:38501077 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
G Ptgr2 prostaglandin reductase 2 enables ISO
IEA
IBA
ISS 		(PMID:19000823)
GO_REF:0000116
GO_REF:0000003
GO_REF:0000033
GO_REF:0000002
GO_REF:0000024 		RGD
RHEA
UniProt
GO_Central
InterPro		 PMID:19000823 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111 		JBrowse link
G Ptgr3 prostaglandin reductase 3 enables IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:23821743) 		GO_Central
Ensembl
RGD		 PMID:23821743 GO_REF:0000033 GO_REF:0000107 NCBI chr18:77,454,435...77,463,785
Ensembl chr18:77,454,435...77,463,785 		JBrowse link
2,4-dienoyl-CoA reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Decr1 2,4-dienoyl-CoA reductase 1 enables TAS
IBA
ISS
IEA
ISO 		GO_REF:0000033
GO_REF:0000024
GO_REF:0000107
(PMID:15531764) 		GO_Central
UniProt
Ensembl
RGD		 PMID:15531764 PMID:2383590 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:70712 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018 		JBrowse link
G Decr2 2,4-dienoyl-CoA reductase 2 enables IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
GO_REF:0000002
PMID:11669066
(PMID:11514237) 		Ensembl
GO_Central
InterPro
RGD		 PMID:11514237 PMID:10333503 PMID:11669066 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:70713, RGD:8553302 NCBI chr10:15,104,907...15,113,281
Ensembl chr10:15,002,926...15,118,479 		JBrowse link
G Nme4 NME/NM23 nucleoside diphosphate kinase 4 enables IEA GO_REF:0000002
GO_REF:0000107 		InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr10:15,619,106...15,622,961
Ensembl chr10:15,002,926...15,118,479 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase NOT|enables ISO (PMID:11669066) RGD PMID:11669066 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511 		JBrowse link
G Rab11fip3 RAB11 family interacting protein 3 enables IEA GO_REF:0000002
GO_REF:0000107 		InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr10:15,002,650...15,086,382
Ensembl chr10:15,002,926...15,118,479 		JBrowse link
2-alkenal reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgr1 prostaglandin reductase 1 enables IDA
IEA
ISO 		PMID:11524419
GO_REF:0000116
GO_REF:0000107
(PMID:25619643) 		RHEA
Ensembl
RGD		 PMID:25619643 PMID:11524419 GO_REF:0000107 GO_REF:0000116, RGD:38501077 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
2-alkenal reductase [NAD(P)+] activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgr1 prostaglandin reductase 1 enables IEA GO_REF:0000003
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srd5a1 steroid 5 alpha-reductase 1 enables IEA GO_REF:0000003
GO_REF:0000116 		UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 enables ISO
IEA 		(PMID:1944596)
GO_REF:0000116
GO_REF:0000003
GO_REF:0000107 		RGD
RHEA
UniProt
Ensembl		 PMID:1944596 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 enables IEA
ISO
ISS 		GO_REF:0000003
GO_REF:0000107
GO_REF:0000116
GO_REF:0000104
(PMID:17986282)
GO_REF:0000024 		UniProt
Ensembl
RHEA
RGD		 PMID:17986282 GO_REF:0000003 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747 		JBrowse link
7-dehydrocholesterol reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr7 7-dehydrocholesterol reductase enables TAS
IEA
ISO
IBA
IMP 		GO_REF:0000003
GO_REF:0000116
(PMID:38297129), (PMID:38297130), (PMID:9465114)
GO_REF:0000033
(PMID:11792727)
GO_REF:0000107 		UniProt
RHEA
RGD
GO_Central
Ensembl		 PMID:9465114 PMID:11792727 PMID:38297129 PMID:38297130 PMID:12031495 More... GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116, RGD:625561, RGD:2316918, RGD:2316916 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
biliberdin reductase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blvra biliverdin reductase A enables IDA
IEA
ISO 		PMID:8020496
GO_REF:0000116
(PMID:7929092), (PMID:8424666), (PMID:8631357) 		RHEA
RGD		 PMID:7929092 PMID:8424666 PMID:8631357 PMID:8020496 GO_REF:0000116, RGD:151356634 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033 		JBrowse link
biliverdin reductase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blvra biliverdin reductase A enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033 		JBrowse link
biliverdin reductase [NAD(P)+] activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blvra biliverdin reductase A enables TAS
IEA
ISO
IBA
IDA 		GO_REF:0000107
GO_REF:0000104
GO_REF:0000002
GO_REF:0000003
(PMID:15081633)
GO_REF:0000033
(PMID:10858451), (PMID:7929092), (PMID:8424666), (PMID:8631357)
PMID:8020496 		Ensembl
UniProt
InterPro
RGD
GO_Central		 PMID:7929092 PMID:8424666 PMID:8631357 PMID:10858451 PMID:15081633 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107, RGD:727549, RGD:151356634 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033 		JBrowse link
G Blvrb biliverdin reductase B enables ISO (PMID:10858451), (PMID:7929092) RGD PMID:7929092 PMID:10858451 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375 		JBrowse link
G ENSRNOG00000064875 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr18:28,314,181...28,314,827 JBrowse link
cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B1 enables IDA RGD PMID:8407226 RGD:8548677 NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
Delta14-sterol reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07021955.1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003
G Lbr lamin B receptor enables ISO
IEA
IBA
ISS 		(PMID:12618959), (PMID:16784888), (PMID:21327084), (PMID:27336722), (PMID:9630650)
GO_REF:0000116
GO_REF:0000003
GO_REF:0000107
GO_REF:0000033
(PMID:18785926), (PMID:22140257)
GO_REF:0000024 		RGD
RHEA
UniProt
Ensembl
GO_Central		 PMID:9630650 PMID:12618959 PMID:16784888 PMID:18785926 PMID:21327084 More... GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 NCBI chr13:93,539,386...93,564,026
Ensembl chr13:93,538,920...93,564,017 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 enables ISO
IEA 		(PMID:16784888)
GO_REF:0000107
GO_REF:0000104
GO_REF:0000117
(PMID:18785926) 		RGD
Ensembl
UniProt		 PMID:16784888 PMID:18785926 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270 		JBrowse link
Delta24(24-1) sterol reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr24 24-dehydrocholesterol reductase enables ISO
IEA
IBA 		(PMID:11519011)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:11519011 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
Delta24-sterol reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr24 24-dehydrocholesterol reductase enables IC
IEA
ISO 		GO_REF:0000003
(PMID:11519011) 		UniProt
RGD		 PMID:11519011 PMID:17210742 GO_REF:0000003, RGD:2316898 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
Delta4-3-oxosteroid 5beta-reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 enables ISO (PMID:16983398) RGD PMID:16983398 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 enables IEA GO_REF:0000002
GO_REF:0000003 		InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
dihydropyrimidine dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpyd dihydropyrimidine dehydrogenase IDA RGD PMID:4128676 RGD:11251754 NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
dihydropyrimidine dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpyd dihydropyrimidine dehydrogenase enables IDA
IEA
ISO
IBA
ISS 		GO_REF:0000107
(PMID:12651209), (PMID:5472365)
GO_REF:0000033
GO_REF:0000024
GO_REF:0000117
GO_REF:0000003
GO_REF:0000116
(PMID:8373446), (PMID:9860876)
(PMID:10410956), (PMID:11988088), (PMID:1512248), (PMID:18075467) 		Ensembl
RGD
GO_Central
UniProt
RHEA		 PMID:1512248 PMID:5472365 PMID:8373446 PMID:9860876 PMID:10410956 More... GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117, RGD:1624989, RGD:8553278, RGD:11251743 NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
dolichal reductase [NAD(P)+] activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhrsx dehydrogenase/reductase X-linked enables ISO (PMID:38821050) RGD PMID:38821050 NCBI chr12:16,299,768...16,304,553
Ensembl chr12:16,299,808...16,304,552 		JBrowse link
enoyl-[acyl-carrier-protein] reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fasn fatty acid synthase enables IEA GO_REF:0000116
GO_REF:0000003 		RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase enables ISO
ISS
IEA 		(PMID:12654921)
GO_REF:0000107
GO_REF:0000116
GO_REF:0000003 		RGD
Ensembl
RHEA
UniProt		 PMID:12654921 PMID:12654921 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116, RGD:8553564 NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863 		JBrowse link
mRNA dihydrouridine synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus3l dihydrouridine synthase 3-like enables ISO
IEA 		(PMID:34556860)
GO_REF:0000116 		RGD
RHEA		 PMID:34556860 GO_REF:0000116 NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655 		JBrowse link
polyprenal reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srd5a3 steroid 5 alpha-reductase 3 enables ISO
IEA
ISS 		(PMID:38821050)
GO_REF:0000003
GO_REF:0000024
GO_REF:0000107
GO_REF:0000116 		RGD
UniProt
Ensembl
RHEA		 PMID:38821050 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747 		JBrowse link
polyprenol dehydrogenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhrsx dehydrogenase/reductase X-linked enables ISO (PMID:38821050) RGD PMID:38821050 NCBI chr12:16,299,768...16,304,553
Ensembl chr12:16,299,808...16,304,552 		JBrowse link
polyprenol reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srd5a3 steroid 5 alpha-reductase 3 enables IEA
IBA 		GO_REF:0000104
GO_REF:0000033 		UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747 		JBrowse link
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c1 aldo-keto reductase family 1, member C1 enables ISO (PMID:8486699) RGD PMID:8486699 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 enables ISO (PMID:8573067) RGD PMID:8573067 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
trans-2-enoyl-CoA reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Decr2 2,4-dienoyl-CoA reductase 2 enables ISO
IEA 		(PMID:10811639), (PMID:11514237)
GO_REF:0000107 		RGD
Ensembl		 PMID:10811639 PMID:11514237 GO_REF:0000107 NCBI chr10:15,104,907...15,113,281
Ensembl chr10:15,002,926...15,118,479 		JBrowse link
G Nme4 NME/NM23 nucleoside diphosphate kinase 4 enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:15,619,106...15,622,961
Ensembl chr10:15,002,926...15,118,479 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase enables ISS
IEA
IBA
ISO 		PMID:10811639
GO_REF:0000003
GO_REF:0000116
GO_REF:0000033
(PMID:16546181)
GO_REF:0000107 		UniProt
RHEA
GO_Central
RGD
Ensembl		 PMID:16546181 PMID:10811639 PMID:10811639 PMID:10811639 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116, RGD:8554268, RGD:8554268, RGD:8554268 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511 		JBrowse link
G Rab11fip3 RAB11 family interacting protein 3 enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:15,002,650...15,086,382
Ensembl chr10:15,002,926...15,118,479 		JBrowse link
tRNA dihydrouridine synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus1l dihydrouridine synthase 1-like enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781 		JBrowse link
G Dus2 dihydrouridine synthase 2 enables ISO
IEA 		(PMID:26429968)
GO_REF:0000002 		RGD
InterPro		 PMID:26429968 GO_REF:0000002 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709 		JBrowse link
G Dus3l dihydrouridine synthase 3-like enables IEA
IBA 		GO_REF:0000104
GO_REF:0000002
GO_REF:0000033 		UniProt
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655 		JBrowse link
G Dus4l dihydrouridine synthase 4-like enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 6:48,228,111...48,242,553
Ensembl chr 6:48,228,111...48,242,449 		JBrowse link
tRNA-dihydrouridine16 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus1l dihydrouridine synthase 1-like enables ISO
IEA
ISS 		(PMID:39354220)
GO_REF:0000116
GO_REF:0000107
GO_REF:0000024 		RGD
RHEA
Ensembl
UniProt		 PMID:39354220 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781 		JBrowse link
tRNA-dihydrouridine17 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus1l dihydrouridine synthase 1-like enables ISO
IEA
ISS 		(PMID:39354220)
GO_REF:0000116
GO_REF:0000107
GO_REF:0000024 		RGD
RHEA
Ensembl
UniProt		 PMID:39354220 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781 		JBrowse link
tRNA-dihydrouridine20 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus2 dihydrouridine synthase 2 enables ISO (PMID:38680565) RGD PMID:38680565 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709 		JBrowse link
tRNA-dihydrouridine47 synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus3l dihydrouridine synthase 3-like enables ISO
ISS 		(PMID:34556860)
GO_REF:0000024 		RGD
UniProt		 PMID:34556860 GO_REF:0000024 NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655 		JBrowse link
very-long-chain enoyl-CoA reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tecr trans-2,3-enoyl-CoA reductase enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000116
GO_REF:0000003
(PMID:12482854), (PMID:24220030)
GO_REF:0000107 		UniProt
RHEA
RGD
Ensembl		 PMID:12482854 PMID:24220030 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr19:24,526,700...24,568,168
Ensembl chr19:24,541,615...24,568,168 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21102
    catalytic activity 6213
      oxidoreductase activity 865
        oxidoreductase activity, acting on the CH-CH group of donors 64
          oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 35
            (+)-pulegone reductase (NADP+) activity 0
            (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity 0
            1,2-dihydrovomilenine reductase activity 0
            1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity 0
            1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity 0
            1-penten-3-one reductase activity 0
            11-hydroxythromboxane B2 dehydrogenase activity 0
            12-hydroxyheptadecatrienoic acid synthase activity 1
            12-oxophytodienoate reductase activity 0
            15-oxoprostaglandin 13-oxidase [NAD(P)+] activity 3
            2'-hydroxydaidzein reductase activity 0
            2'-hydroxyisoflavone reductase activity 0
            2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity 0
            2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity 0
            2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity 0
            2,4-dienoyl-CoA reductase (NADPH) activity 5
            2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity 0
            2-alkenal reductase [NAD(P)+] activity + 1
            2-chloroacrylate reductase activity 0
            2-coumarate reductase activity 0
            2-enoate reductase activity 0
            2-hexadecenal reductase activity 0
            2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity 0
            3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) activity 0
            3-methyleneoxindole reductase activity 0
            4-hydroxy-tetrahydrodipicolinate reductase 0
            5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity 0
            7-dehydrocholesterol reductase activity 1
            Delta14-sterol reductase activity 3
            Delta24(24-1) sterol reductase activity 1
            Delta24-sterol reductase activity 1
            N-ethylmaleimide reductase activity 0
            RNA dihydrouridine synthase activity + 4
            acrolein reductase activity 0
            acryloyl-CoA reductase (NADH) activity 0
            acryloyl-CoA reductase (NADPH) activity 0
            acyl-CoA dehydrogenase (NADP+) activity 0
            alpha-santonin 1,2-reductase activity 0
            anthocyanidin reductase activity 0
            arogenate dehydrogenase [NAD(P)+] activity + 0
            beta-nitroacrylate reductase activity 0
            biliverdin reductase [NAD(P)+] activity + 3
            biochanin-A reductase activity 0
            cinnamate reductase activity 0
            cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity 1
            cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity 0
            cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity 0
            cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity 0
            cis-2-enoyl-CoA reductase (NADPH) activity 0
            cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity 0
            cis-dihydroethylcatechol dehydrogenase activity 0
            citronellyl-CoA dehydrogenase activity 0
            crotonyl-CoA reductase activity 0
            cucurbitacin Delta23 reductase [NAD(P)H] activity 0
            curcumin reductase (NADP+) activity 0
            cyclohexadienyl dehydrogenase activity 0
            dibenzothiophene dihydrodiol dehydrogenase activity 0
            dihydroorotate dehydrogenase (NAD+) activity 0
            dihydroorotate dehydrogenase (NADP+) activity 0
            dihydropyrimidine dehydrogenase (NAD+) activity 1
            dihydropyrimidine dehydrogenase (NADP+) activity 1
            dolichal reductase [NAD(P)+] activity 1
            enone reductase activity + 5
            enoyl-[acyl-carrier-protein] reductase activity (NAD(P)H) + 2
            fumarate reductase (NADH) activity 0
            furaneol oxidoreductase activity 0
            geissoschizine dehydrogenase activity 0
            geranylgeranyl diphosphate reductase activity 0
            kynurenate-7,8-dihydrodiol dehydrogenase activity 0
            maleylacetate reductase activity 0
            meso-tartrate dehydrogenase activity 0
            phloroglucinol reductase activity 0
            phthalate 3,4-cis-dihydrodiol dehydrogenase activity 0
            phthalate 4,5-cis-dihydrodiol dehydrogenase activity 0
            pimeloyl-CoA dehydrogenase activity 0
            polyprenal reductase activity 1
            polyprenol dehydrogenase activity 1
            polyprenol reductase activity 1
            precorrin-2 dehydrogenase activity 0
            precorrin-6A reductase activity 0
            prephenate dehydrogenase (NAD+) activity 0
            prephenate dehydrogenase (NADP+) activity 0
            protochlorophyllide reductase activity 0
            trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity 2
            trans-2-enoyl-CoA reductase (NADH) activity 0
            trans-2-enoyl-CoA reductase (NADPH) activity 4
            trans-4-hexen-3-one reductase activity 0
            very-long-chain enoyl-CoA reductase activity 1
            xanthommatin reductase activity 0
            zeatin reductase activity 0
paths to the root