ONTOLOGY REPORT - ANNOTATIONS
Term: oxidoreductase activity, acting on the CH-CH group of donors
Accession: GO:0016627
browse the term
Definition: Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
Synonyms: narrow_synonym: oxidoreductase activity, acting on the CH-CH group of donors, other acceptors
xref: EC:1.3; Reactome:R-HSA-9661710 "An unknown oxidase oxidises D-UBGN to UBN"; reactome:R-HSA-2995334 "COX15 transforms heme O to heme A"
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Acad11
acyl-CoA dehydrogenase family, member 11
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560
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Cox15
cytochrome c oxidase assembly homolog COX15
enables
ISO
(PMID:12474143)
RGD
PMID:12474143
NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
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Sdha
succinate dehydrogenase complex flavoprotein subunit A
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535
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Tecr
trans-2,3-enoyl-CoA reductase
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr19:24,526,700...24,568,168
Ensembl chr19:24,541,615...24,568,168
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Tecrl
trans-2,3-enoyl-CoA reductase-like
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr14:24,732,241...24,805,272
Ensembl chr14:24,732,241...24,805,272
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Tecrl2
trans-2,3-enoyl-CoA reductase like 2
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 1:47,263,647...47,264,682
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Tbxas1
thromboxane A synthase 1
enables
IEA
GO_REF:0000116
RHEA
GO_REF:0000116
NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
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Ptgr1
prostaglandin reductase 1
enables
IBA ISO IEA IDA
GO_REF:0000033 (PMID:11688989) (PMID:25619643) GO_REF:0000107 PMID:11524419
GO_Central RGD Ensembl
PMID:11688989 PMID:25619643 PMID:11524419
GO_REF:0000033 GO_REF:0000107, RGD:38501077
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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Ptgr2
prostaglandin reductase 2
enables
ISO IBA IEA ISS
(PMID:19000823) GO_REF:0000033 GO_REF:0000107 GO_REF:0000002 GO_REF:0000024
RGD GO_Central Ensembl InterPro UniProt
PMID:19000823
GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111
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Ptgr3
prostaglandin reductase 3
enables
IBA ISO
GO_REF:0000033 (PMID:23821743)
GO_Central RGD
PMID:23821743
GO_REF:0000033
NCBI chr18:77,454,435...77,463,785
Ensembl chr18:77,454,435...77,463,785
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Decr1
2,4-dienoyl-CoA reductase 1
enables
TAS IBA ISS IEA ISO
GO_REF:0000033 GO_REF:0000024 GO_REF:0000107 (PMID:15531764)
GO_Central UniProt Ensembl RGD
PMID:15531764 PMID:2383590
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:70712
NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
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Decr2
2,4-dienoyl-CoA reductase 2
enables
IDA IBA IEA ISO
GO_REF:0000033 GO_REF:0000002 PMID:11669066 (PMID:11514237)
GO_Central InterPro RGD
PMID:11514237 PMID:10333503 PMID:11669066
GO_REF:0000002 GO_REF:0000033, RGD:70713 , RGD:8553302
NCBI chr10:15,104,907...15,113,281
Ensembl chr10:15,002,926...15,118,479
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Nme4
NME/NM23 nucleoside diphosphate kinase 4
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr10:15,114,624...15,118,479
Ensembl chr10:15,002,926...15,118,479
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Pecr
peroxisomal trans-2-enoyl-CoA reductase
NOT|enables
ISO
(PMID:11669066)
RGD
PMID:11669066
NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
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Rab11fip3
RAB11 family interacting protein 3
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr10:15,002,650...15,086,382
Ensembl chr10:15,002,926...15,118,479
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Ptgr1
prostaglandin reductase 1
enables
IDA IEA ISO
PMID:11524419 GO_REF:0000107 (PMID:25619643)
Ensembl RGD
PMID:25619643 PMID:11524419
GO_REF:0000107, RGD:38501077
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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Ivd
isovaleryl-CoA dehydrogenase
enables
IDA IBA ISO
GO_REF:0000033 (PMID:3597357), (PMID:7640268) PMID:6401713
GO_Central RGD
PMID:3597357 PMID:7640268 PMID:2777793 PMID:6401713
GO_REF:0000033, RGD:631718 , RGD:8554099
NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
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Srd5a1
steroid 5 alpha-reductase 1
enables
TAS ISO IBA ISS IDA
MGI:1857454 (PMID:15249131), (PMID:21731732) GO_REF:0000033 GO_REF:0000024 (PMID:17986282)
RGD GO_Central UniProt
PMID:15249131 PMID:17986282 PMID:21731732 PMID:2476440 PMID:7482629
GO_REF:0000024 GO_REF:0000033, RGD:730219 , RGD:2326071
NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
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Srd5a2
steroid 5 alpha-reductase 2
enables
IDA ISO IBA
MGI:2178039 (PMID:11606430), (PMID:15249131), (PMID:35613877) GO_REF:0000033
RGD GO_Central
PMID:11606430 PMID:15249131 PMID:35613877 PMID:1527072 PMID:7662592
GO_REF:0000033, RGD:729939 , RGD:2326072
NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
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Srd5a3
steroid 5 alpha-reductase 3
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747
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Akr1d1
aldo-keto reductase family 1, member D1
enables
IDA
PMID:1789929
MGI
PMID:1789929
RGD:8553834
NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
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Srd5a1
steroid 5 alpha-reductase 1
enables
IEA
GO_REF:0000003 GO_REF:0000116
UniProt RHEA
GO_REF:0000003 GO_REF:0000116
NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
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Srd5a2
steroid 5 alpha-reductase 2
enables
ISO
(PMID:1944596)
RGD
PMID:1944596
NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
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Srd5a3
steroid 5 alpha-reductase 3
enables
IEA ISO ISS
GO_REF:0000003 (PMID:17986282) GO_REF:0000024
UniProt RGD
PMID:17986282
GO_REF:0000003 GO_REF:0000024
NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747
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Dhcr7
7-dehydrocholesterol reductase
enables
TAS ISO IBA IEA IMP
(PMID:38297129), (PMID:38297130), (PMID:9465114) GO_REF:0000033 (PMID:11792727) GO_REF:0000107
RGD GO_Central Ensembl
PMID:9465114 PMID:11792727 PMID:38297129 PMID:38297130 PMID:12031495 PMID:9831636 PMID:10666310 More...
GO_REF:0000033 GO_REF:0000107, RGD:625561 , RGD:2316918 , RGD:2316916
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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Acad10
acyl-CoA dehydrogenase family, member 10
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:34,901,211...34,943,973
Ensembl chr12:34,901,219...34,982,521
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Acad11
acyl-CoA dehydrogenase family, member 11
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560
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Acad8
acyl-CoA dehydrogenase family, member 8
enables
IEA
GO_REF:0000117
UniProt
GO_REF:0000117
NCBI chr 8:25,382,271...25,406,404
Ensembl chr 8:25,382,273...25,406,414
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Acad9
acyl-CoA dehydrogenase family, member 9
enables
IBA IEA
GO_REF:0000033 GO_REF:0000117
GO_Central UniProt
GO_REF:0000033 GO_REF:0000117
NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
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Acadm
acyl-CoA dehydrogenase medium chain
enables
IDA ISS ISO
GO_REF:0000024 (PMID:19224950), (PMID:2393404)
UniProt RGD
PMID:2393404 PMID:19224950 PMID:15358373 PMID:3968063
GO_REF:0000024, RGD:1358266 , RGD:2317678
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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Acads
acyl-CoA dehydrogenase short chain
enables
NAS IEA ISO IDA
GO_REF:0000117 (PMID:11134486), (PMID:3597357)
UniProt RGD
PMID:3597357 PMID:11134486 PMID:2777793 PMID:3968063 PMID:8952487 PMID:9459013 More...
GO_REF:0000117, RGD:631718 , RGD:2317678 , RGD:1598701 , RGD:1598700
NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
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Acadsb
acyl-CoA dehydrogenase, short/branched chain
enables
IDA IBA IEA
GO_REF:0000033 GO_REF:0000117
GO_Central UniProt RGD
PMID:8660691
GO_REF:0000033 GO_REF:0000117, RGD:631739
NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
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Acadvl
acyl-CoA dehydrogenase, very long chain
enables
IDA ISO
(PMID:9461620), (PMID:9599005)
RGD
PMID:9461620 PMID:9599005 PMID:8034667
RGD:631729
NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
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Aldh2
aldehyde dehydrogenase 2 family member
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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Ivd
isovaleryl-CoA dehydrogenase
enables
IEA
GO_REF:0000117
UniProt
GO_REF:0000117
NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
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Acox1
acyl-CoA oxidase 1
enables
ISO IEA IDA ISS
(PMID:18536048), (PMID:32169171), (PMID:7876265), (PMID:8117268) GO_REF:0000107 GO_REF:0000002 UniProtKB:P13711 (PMID:17458872) PMID:7462191 GO_REF:0000024
RGD Ensembl InterPro UniProt
PMID:7876265 PMID:8117268 PMID:17458872 PMID:18536048 PMID:32169171 PMID:7462191 More...
GO_REF:0000002 GO_REF:0000024 GO_REF:0000107, RGD:14402446
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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Acox2
acyl-CoA oxidase 2
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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Acox3
acyl-CoA oxidase 3, pristanoyl
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr14:75,133,986...75,176,767
Ensembl chr14:75,094,676...75,176,205
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Acoxl
acyl-CoA oxidase-like
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 3:115,061,069...115,367,032
Ensembl chr 3:115,061,060...115,364,686
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Crat
carnitine O-acetyltransferase
enables
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:23485643)
UniProt Ensembl RGD
PMID:23485643
GO_REF:0000024 GO_REF:0000107
NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
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Retsat
retinol saturase
enables
ISS ISO IBA IEA
PMID:15358783 (PMID:15358783) GO_REF:0000033 (MGI:3522397|PMID:15358783) GO_REF:0000107
RGD GO_Central Ensembl
PMID:15358783 PMID:15358783
GO_REF:0000033 GO_REF:0000107 MGI:3522397 , RGD:8553455
NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310
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Blvra
biliverdin reductase A
enables
IDA ISO
PMID:8020496 (PMID:7929092), (PMID:8424666), (PMID:8631357)
RGD
PMID:7929092 PMID:8424666 PMID:8631357 PMID:8020496
RGD:151356634
NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033
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Blvra
biliverdin reductase A
enables
IEA
GO_REF:0000116
RHEA
GO_REF:0000116
NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033
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Blvra
biliverdin reductase A
enables
TAS IEA ISO IBA IDA
GO_REF:0000003 (PMID:15081633) GO_REF:0000033 (PMID:10858451), (PMID:7929092), (PMID:8424666), (PMID:8631357) PMID:8020496
UniProt RGD GO_Central
PMID:7929092 PMID:8424666 PMID:8631357 PMID:10858451 PMID:15081633 PMID:1371282 PMID:8020496 More...
GO_REF:0000003 GO_REF:0000033, RGD:727549 , RGD:151356634
NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033
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Blvrb
biliverdin reductase B
enables
IBA ISO
GO_REF:0000033 (PMID:10858451), (PMID:7929092)
GO_Central RGD
PMID:7929092 PMID:10858451
GO_REF:0000033
NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
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Akr1b1
aldo-keto reductase family 1 member B1
enables
IDA
RGD
PMID:8407226
RGD:8548677
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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Cpox
coproporphyrinogen oxidase
enables
IDA ISO IBA IEA
(PMID:7607249), (PMID:8407975) GO_REF:0000033 GO_REF:0000107 (PMID:7987309)
RGD GO_Central Ensembl
PMID:7607249 PMID:7987309 PMID:8407975 PMID:11079369
GO_REF:0000033 GO_REF:0000107, RGD:1600956
NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746
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Rsad1
radical S-adenosyl methionine domain containing 1
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr10:79,485,253...79,499,616
Ensembl chr10:79,489,909...79,499,573
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AABR07021955.1
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
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Lbr
lamin B receptor
enables
ISO IEA IBA ISS
(PMID:12618959), (PMID:16784888), (PMID:21327084), (PMID:27336722), (PMID:9630650) (PMID:18785926), (PMID:22140257) GO_REF:0000104 GO_REF:0000033 (MGI:3822946|PMID:18785926), (MGI:5308142|PMID:22140257) GO_REF:0000024
RGD UniProt GO_Central
PMID:9630650 PMID:12618959 PMID:16784888 PMID:18785926 PMID:21327084 PMID:22140257 PMID:27336722 More...
GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 MGI:3822946 MGI:5308142
NCBI chr13:93,539,386...93,564,026
Ensembl chr13:93,538,920...93,564,017
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Tm7sf2
transmembrane 7 superfamily member 2
enables
ISO IBA
(PMID:16784888) (PMID:18785926) GO_REF:0000033 (MGI:3822946|PMID:18785926)
RGD GO_Central
PMID:16784888 PMID:18785926
GO_REF:0000033 MGI:3822946
NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270
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Dhcr24
24-dehydrocholesterol reductase
enables
ISO IBA
(PMID:11519011) GO_REF:0000033
RGD GO_Central
PMID:11519011
GO_REF:0000033
NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
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Dhcr24
24-dehydrocholesterol reductase
enables
IC ISO
(PMID:11519011)
RGD
PMID:11519011 PMID:17210742
RGD:2316898
NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
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Akr1c3
aldo-keto reductase family 1, member C3
enables
ISO
(PMID:16983398)
RGD
PMID:16983398
NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
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Akr1d1
aldo-keto reductase family 1, member D1
enables
IEA
GO_REF:0000002 GO_REF:0000003
InterPro UniProt
GO_REF:0000002 GO_REF:0000003
NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
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Dhodh
dihydroorotate dehydrogenase (quinone)
enables
IEA ISO
GO_REF:0000003 GO_REF:0000107 (PMID:8925840) GO_REF:0000116
UniProt Ensembl RGD RHEA
PMID:8925840
GO_REF:0000003 GO_REF:0000107 GO_REF:0000116
NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
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Dhodh
dihydroorotate dehydrogenase (quinone)
enables
NAS ISO IBA IEA IDA
(PMID:20413687), (PMID:6249586) GO_REF:0000033 GO_REF:0000002
RGD GO_Central InterPro
PMID:6249586 PMID:20413687 PMID:7660999 PMID:1313236 PMID:15044733
GO_REF:0000002 GO_REF:0000033, RGD:632559 , RGD:5132611 , RGD:2316233
NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
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Dpyd
dihydropyrimidine dehydrogenase
IDA
RGD
PMID:4128676
RGD:11251754
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
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Dpyd
dihydropyrimidine dehydrogenase
enables
IDA ISO IBA ISS IEA
(PMID:12651209), (PMID:5472365) GO_REF:0000033 GO_REF:0000024 GO_REF:0000117 GO_REF:0000003 GO_REF:0000116 (PMID:8373446), (PMID:9860876) (PMID:10410956), (PMID:11988088), (PMID:1512248), (PMID:18075467)
RGD GO_Central UniProt RHEA
PMID:1512248 PMID:5472365 PMID:8373446 PMID:9860876 PMID:10410956 PMID:11988088 PMID:12651209 PMID:18075467 PMID:7626590 PMID:8373446 PMID:1544906 More...
GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 GO_REF:0000117, RGD:1624989 , RGD:8553278 , RGD:11251743
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
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Fasn
fatty acid synthase
enables
IEA
GO_REF:0000116 GO_REF:0000003
RHEA UniProt
GO_REF:0000003 GO_REF:0000116
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Mecr
mitochondrial trans-2-enoyl-CoA reductase
enables
ISO ISS IEA
(PMID:12654921) GO_REF:0000107
RGD Ensembl
PMID:12654921 PMID:12654921
GO_REF:0000107, RGD:8553564
NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863
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Gcdh
glutaryl-CoA dehydrogenase
enables
IDA IBA ISO
GO_REF:0000033 (PMID:8541831)
GO_Central RGD
PMID:8541831 PMID:2899130 PMID:6895440
GO_REF:0000033, RGD:1598698 , RGD:1598697
NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681
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Acad11
acyl-CoA dehydrogenase family, member 11
enables
ISO
(PMID:21237683)
RGD
PMID:21237683
NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560
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Acad9
acyl-CoA dehydrogenase family, member 9
enables
ISO
(PMID:16020546)
RGD
PMID:16020546
NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
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Acadl
acyl-CoA dehydrogenase, long chain
enables
IDA ISO IBA IEA
(PMID:9861014) GO_REF:0000033 GO_REF:0000002 (MGI:1321427|PMID:9861014)
RGD GO_Central InterPro
PMID:9861014 PMID:3968063
GO_REF:0000002 GO_REF:0000033 MGI:1321427 , RGD:2317678
NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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Acadvl
acyl-CoA dehydrogenase, very long chain
enables
IDA IEA ISO
GO_REF:0000107 (PMID:7668252)
Ensembl RGD
PMID:7668252 PMID:8034667
GO_REF:0000107, RGD:631729
NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
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Acad11
acyl-CoA dehydrogenase family, member 11
enables
ISO
(PMID:21237683)
RGD
PMID:21237683
NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560
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Acad9
acyl-CoA dehydrogenase family, member 9
enables
ISO
(PMID:16020546)
RGD
PMID:16020546
NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
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Acadm
acyl-CoA dehydrogenase medium chain
enables
ISO IEA IBA
(PMID:1902818), (PMID:19224950), (PMID:1970566), (PMID:3597357) (MGI:4412440|PMID:18459129) GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000033
RGD InterPro UniProt Ensembl GO_Central
PMID:1902818 PMID:1970566 PMID:3597357 PMID:18459129 PMID:19224950
GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 MGI:4412440
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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Dus3l
dihydrouridine synthase 3-like
enables
ISO IEA
(PMID:34556860) GO_REF:0000107
RGD Ensembl
PMID:34556860
GO_REF:0000107
NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655
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Bdh2
3-hydroxybutyrate dehydrogenase 2
enables
ISS ISO
GO_REF:0000024 (MGI:4820913|PMID:20550936)
UniProt RGD
PMID:20550936
GO_REF:0000024 MGI:4820913
NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072
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Dhcr24
24-dehydrocholesterol reductase
enables
ISO
(PMID:11519011)
RGD
PMID:11519011
NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
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Srd5a3
steroid 5 alpha-reductase 3
enables
ISS ISO
GO_REF:0000024 (PMID:20637498)
UniProt RGD
PMID:20637498
GO_REF:0000024
NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747
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Ppox
protoporphyrinogen oxidase
enables
IDA ISO IBA
(PMID:3346226), (PMID:7607249), (PMID:8554330) GO_REF:0000033 (PMID:7713909)
RGD GO_Central
PMID:3346226 PMID:7607249 PMID:7713909 PMID:8554330 PMID:3663105
GO_REF:0000033, RGD:1599180
NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805
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Acaa1a
acetyl-CoA acyltransferase 1A
enables
ISO IGI
(PMID:2882519)
RGD
PMID:2882519 PMID:2882519
RGD:8554082
NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624
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Acadl
acyl-CoA dehydrogenase, long chain
enables
ISO IBA
(MGI:1321427|PMID:9861014) GO_REF:0000033 (PMID:9861014)
RGD GO_Central
PMID:9861014
GO_REF:0000033 MGI:1321427
NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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Acox1
acyl-CoA oxidase 1
enables
IDA IBA ISO
GO_REF:0000033 (PMID:17603022)
GO_Central RGD
PMID:17603022 PMID:1400324
GO_REF:0000033, RGD:2299949
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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Acox2
acyl-CoA oxidase 2
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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Srd5a3
steroid 5 alpha-reductase 3
enables
IEA ISO
GO_REF:0000003 UniProtKB:P40526 (PMID:20637498)
UniProt RGD
PMID:20637498
GO_REF:0000003
NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747
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Acox3
acyl-CoA oxidase 3, pristanoyl
enables
TAS IBA IDA
GO_REF:0000033
GO_Central RGD
PMID:8706733 PMID:8654595 PMID:8026493 PMID:1400324
GO_REF:0000033, RGD:68737 , RGD:2299971 , RGD:2299969 , RGD:2299949
NCBI chr14:75,133,986...75,176,767
Ensembl chr14:75,094,676...75,176,205
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Acadsb
acyl-CoA dehydrogenase, short/branched chain
enables
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:11013134), (PMID:7698750)
UniProt Ensembl RGD
PMID:7698750 PMID:11013134
GO_REF:0000024 GO_REF:0000107
NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
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Acads
acyl-CoA dehydrogenase short chain
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
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Acadsb
acyl-CoA dehydrogenase, short/branched chain
enables
ISO IDA
(PMID:7698750) PMID:8660691
RGD
PMID:7698750 PMID:8660691
RGD:631739
NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
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Ivd
isovaleryl-CoA dehydrogenase
enables
IEA
GO_REF:0000117
UniProt
GO_REF:0000117
NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
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Sdha
succinate dehydrogenase complex flavoprotein subunit A
contributes_to enables
IMP ISO ISS IBA IEA
(PMID:7550341) GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 (PMID:24781757)
RGD UniProt GO_Central Ensembl
PMID:7550341 PMID:24781757 PMID:16520240
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:2306906
NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535
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Sdhb
succinate dehydrogenase complex iron sulfur subunit B
enables
IMP ISO ISS IEA
(PMID:26925370), (PMID:27604842) GO_REF:0000024 GO_REF:0000107
RGD UniProt Ensembl
PMID:26925370 PMID:27604842 PMID:16520240
GO_REF:0000024 GO_REF:0000107, RGD:2306906
NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
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Sdhd
succinate dehydrogenase complex subunit D
enables
ISO
MGI:3526521 (PMID:15572694)
RGD
PMID:15572694
NCBI chr 8:50,944,702...50,954,298
Ensembl chr 8:50,944,704...50,954,238
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Akr1c1
aldo-keto reductase family 1, member C1
enables
ISO
(PMID:8486699)
RGD
PMID:8486699
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akr1c2
aldo-keto reductase family 1, member C2
enables
ISO
(PMID:8573067)
RGD
PMID:8573067
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Decr2
2,4-dienoyl-CoA reductase 2
enables
ISO
(PMID:10811639)
RGD
PMID:10811639
NCBI chr10:15,104,907...15,113,281
Ensembl chr10:15,002,926...15,118,479
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Pecr
peroxisomal trans-2-enoyl-CoA reductase
enables
ISS IBA ISO IEA
PMID:10811639 GO_REF:0000033 (PMID:16546181) GO_REF:0000107
GO_Central RGD Ensembl
PMID:16546181 PMID:10811639 PMID:10811639 PMID:10811639
GO_REF:0000033 GO_REF:0000107, RGD:8554268 , RGD:8554268 , RGD:8554268
NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
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Dus1l
dihydrouridine synthase 1-like
enables
IEA IBA
GO_REF:0000002 GO_REF:0000033
InterPro GO_Central
GO_REF:0000002 GO_REF:0000033
NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781
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Dus2
dihydrouridine synthase 2
enables
ISO IBA
(PMID:26429968) GO_REF:0000033
RGD GO_Central
PMID:26429968
GO_REF:0000033
NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709
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Dus3l
dihydrouridine synthase 3-like
enables
IEA IBA
GO_REF:0000104 GO_REF:0000033
UniProt GO_Central
GO_REF:0000033 GO_REF:0000104
NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655
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Dus4l
dihydrouridine synthase 4-like
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 6:48,228,111...48,242,553
Ensembl chr 6:48,228,111...48,242,449
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Dus1l
dihydrouridine synthase 1-like
enables
IEA
GO_REF:0000116
RHEA
GO_REF:0000116
NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781
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Dus1l
dihydrouridine synthase 1-like
enables
IEA
GO_REF:0000116
RHEA
GO_REF:0000116
NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781
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Dus2
dihydrouridine synthase 2
enables
ISO
(PMID:38680565)
RGD
PMID:38680565
NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709
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Dus3l
dihydrouridine synthase 3-like
enables
ISO IEA ISS
(PMID:34556860) GO_REF:0000107 GO_REF:0000024
RGD Ensembl UniProt
PMID:34556860
GO_REF:0000024 GO_REF:0000107
NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655
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Tecr
trans-2,3-enoyl-CoA reductase
enables
ISS ISO IEA
GO_REF:0000024 (PMID:12482854), (PMID:24220030) GO_REF:0000107
UniProt RGD Ensembl
PMID:12482854 PMID:24220030
GO_REF:0000024 GO_REF:0000107
NCBI chr19:24,526,700...24,568,168
Ensembl chr19:24,541,615...24,568,168
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Acad11
acyl-CoA dehydrogenase family, member 11
enables
ISO
(PMID:21237683)
RGD
PMID:21237683
NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560
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Acadvl
acyl-CoA dehydrogenase, very long chain
enables
IDA IBA IEA ISO
GO_REF:0000033 GO_REF:0000107 (PMID:9461620)
GO_Central Ensembl RGD
PMID:9461620 PMID:1730632
GO_REF:0000033 GO_REF:0000107, RGD:2317689
NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
molecular_function
20736
catalytic activity
6109
oxidoreductase activity
859
oxidoreductase activity, acting on the CH-CH group of donors
62
2-furoyl-CoA dehydrogenase activity
0
all-trans-retinol 13,14-reductase activity
1
carvone reductase activity
0
coproporphyrinogen dehydrogenase activity
0
cyclohexanone dehydrogenase activity
0
dihydroorotate dehydrogenase activity +
1
isoquinoline 1-oxidoreductase activity
0
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor +
33
oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor +
0
oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor +
0
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor +
10
oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor +
4
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor +
12
peptidyl-oxazoline dehydrogenase activity
0
peptidyl-thiazoline dehydrogenase activity
0
phytoene dehydrogenase activity
0
protoporphyrinogen oxidase activity +
1
quinaldate 4-oxidoreductase activity
0
quinoline 2-oxidoreductase activity
0
quinoline-4-carboxylate 2-oxidoreductase activity
0
steroid dehydrogenase activity, acting on the CH-CH group of donors +
4
succinate dehydrogenase activity +
3