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ONTOLOGY REPORT - ANNOTATIONS


Term:amino acid binding
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Accession:GO:0016597 term browser browse the term
Definition:Binding to an amino acid, organic acids containing one or more amino substituents.



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amino acid binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS1 alanyl-tRNA synthetase 1 enables IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:2040280 PMID:21873635 RGD:2302982 NCBI chr 6:13,298,336...13,321,423
Ensembl chr 6:13,298,348...13,321,364
JBrowse link
G AARS2 alanyl-tRNA synthetase 2, mitochondrial enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:39,301,020...39,314,296
Ensembl chr 7:39,299,460...39,313,778
JBrowse link
G AGXT alanine--glyoxylate and serine--pyruvate aminotransferase enables IEA
ISO
Ensembl
RGD
PMID:12383475 GO_REF:0000107 RGD:1599457 NCBI chr15:139,720,648...139,730,737
Ensembl chr15:139,720,612...139,730,736
JBrowse link
G ASS1 argininosuccinate synthase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:270,531,434...270,586,364
Ensembl chr 1:270,531,589...270,586,361
JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase enables IEA InterPro GO_REF:0000002 NCBI chr 3:111,887,017...111,914,511
Ensembl chr 3:111,887,020...111,914,495
JBrowse link
G CASR calcium sensing receptor enables ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr13:138,279,785...138,364,934
Ensembl chr13:138,280,363...138,364,253
JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 enables IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:17322279 PMID:21873635 RGD:1625578 NCBI chr 4:130,485,305...130,617,534
Ensembl chr 4:130,483,878...130,617,531
JBrowse link
G DDAH2 dimethylarginine dimethylaminohydrolase 2 enables IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:17322279 PMID:21873635 RGD:1625578 NCBI chr 7:23,838,993...23,842,514
Ensembl chr 7:23,838,993...23,842,516
JBrowse link
G DDC dopa decarboxylase ISO amino acid derivative, L-DOPA RGD PMID:10569946 RGD:4139897 NCBI chr 9:136,496,364...136,571,220
Ensembl chr 9:136,495,891...136,571,197
JBrowse link
G DPYS dihydropyrimidinase ISO RGD PMID:8307005 RGD:1624990 NCBI chr 4:32,791,152...32,879,489
Ensembl chr 4:32,789,460...32,879,489
JBrowse link
G FMO3 flavin containing dimethylaniline monoxygenase 3 ISO RGD PMID:17173378 RGD:1626480 NCBI chr 9:63,757,928...63,777,075
Ensembl chr 9:63,757,964...63,801,493
JBrowse link
G GCHFR GTP cyclohydrolase I feedback regulator ISO RGD PMID:11818540 RGD:2298660 NCBI chr 1:130,559,223...130,563,598
Ensembl chr 1:130,554,976...130,563,562
JBrowse link
G GFPT1 glutamine--fructose-6-phosphate transaminase 1 ISO glutamine, fructose 6-phosphate RGD PMID:10898949 RGD:1625426 NCBI chr 3:73,028,750...73,086,191
Ensembl chr 3:72,983,188...73,085,319
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 ISO RGD PMID:14522984 RGD:1582383 NCBI chr 6:20,407,203...20,431,849
Ensembl chr 6:20,407,198...20,432,068
JBrowse link
G HDC histidine decarboxylase ISO RGD PMID:5898 PMID:4449071 PMID:7075603 PMID:9525922 PMID:12204113 More... RGD:2303726 RGD:2303727 RGD:2303728 RGD:2303733 RGD:2303734 RGD:2303735 NCBI chr 1:121,505,677...121,525,416
Ensembl chr 1:121,505,742...121,525,255
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:10719243 PMID:11513477 RGD:2290190 RGD:2290543 NCBI chr17:9,245,283...9,260,140
Ensembl chr17:9,245,196...9,260,491
JBrowse link
G KARS1 lysyl-tRNA synthetase 1 ISO lysine RGD PMID:3988754 PMID:7082655 PMID:7372681 RGD:2303393 RGD:2303394 RGD:2303396 NCBI chr 6:12,057,475...12,073,749
Ensembl chr 6:12,056,571...12,073,749
JBrowse link
G LOC110256626 proline dehydrogenase 1, mitochondrial ISO RGD PMID:8373828 RGD:1599203 NCBI chr14:51,624,919...51,644,467 JBrowse link
G MAT1A methionine adenosyltransferase 1A ISO methionine analog RGD PMID:10873471 PMID:12888348 RGD:1599916 RGD:7242772 NCBI chr14:82,109,405...82,126,487
Ensembl chr14:82,109,404...82,127,049
JBrowse link
G MAT2A methionine adenosyltransferase 2A ISO methionine RGD PMID:12029623 RGD:727376 NCBI chr 3:59,220,203...59,225,097
Ensembl chr 3:59,211,157...59,225,261
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:11730351 RGD:1601423 NCBI chr14:54,546,978...54,652,780
Ensembl chr14:54,546,981...54,652,759
JBrowse link
G OTC ornithine transcarbamylase enables IEA
ISO
InterPro
RGD
PMID:2290837 GO_REF:0000002 RGD:1582378 NCBI chr  X:34,322,398...34,391,711
Ensembl chr  X:34,322,298...34,391,837
JBrowse link
G PAH phenylalanine hydroxylase ISO RGD PMID:16953590 RGD:1601531 NCBI chr 5:81,385,401...81,460,569
Ensembl chr 5:81,236,096...81,463,452
JBrowse link
G SCLY selenocysteine lyase enables ISO PMID:20164179 CAFA PMID:20164179 RGD:12793035 NCBI chr15:137,637,076...137,674,726
Ensembl chr15:137,637,071...137,674,736
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO binds but cannot cleave; threonine is an inhibitor RGD PMID:3110140 RGD:2300383 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,414,446...60,435,450
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 ISO binds but cannot cleave; threonine is an inhibitor RGD PMID:3110140 RGD:2300383 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,321
JBrowse link
G SLC1A3 solute carrier family 1 member 3 enables ISO (MGI:65019|PMID:7903437) MGI PMID:7903437 MGI:65019 NCBI chr16:21,873,691...21,965,315
Ensembl chr16:21,873,691...21,968,671
JBrowse link
G TAT tyrosine aminotransferase ISO RGD PMID:12717026 RGD:1582407 NCBI chr 6:14,571,311...14,583,203
Ensembl chr 6:14,570,587...14,583,177
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase ISO RGD PMID:3899109 PMID:7236232 PMID:10719243 RGD:2290190 RGD:2291804 RGD:2303721 NCBI chr 8:44,708,722...44,725,954
Ensembl chr 8:44,708,746...44,740,980
JBrowse link
G TH tyrosine hydroxylase ISO L-tyrosine RGD PMID:15639226 PMID:19489646 PMID:20025246 RGD:1580027 RGD:4139886 RGD:4139888 NCBI chr 2:1,499,628...1,506,180
Ensembl chr 2:1,499,618...1,506,615
JBrowse link
arginine binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:47,261,905...47,266,729
Ensembl chr14:47,261,908...47,266,811
JBrowse link
G CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 NOT|enables ISO (PMID:26972053) UniProt PMID:26972053 NCBI chr 3:11,956,289...12,039,913
Ensembl chr 3:11,956,290...12,039,562
JBrowse link
G NAGS N-acetylglutamate synthase enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:19,170,398...19,173,968
Ensembl chr12:19,169,961...19,174,747
JBrowse link
G NOS2 nitric oxide synthase 2 enables IEA Ensembl GO_REF:0000107 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,944...44,327,111
JBrowse link
G NOS3 nitric oxide synthase 3 enables IEA Ensembl GO_REF:0000107 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
G PADI4 peptidyl arginine deiminase 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:75,935,909...75,966,275
Ensembl chr 6:75,935,903...75,966,169
JBrowse link
G RARS1 arginyl-tRNA synthetase 1 ISO RGD PMID:7082655 RGD:2303394 NCBI chr16:55,373,739...55,412,076
Ensembl chr16:55,373,726...55,412,117
JBrowse link
G TM4SF5 transmembrane 4 L six family member 5 enables IEA Ensembl GO_REF:0000107 NCBI chr12:52,110,732...52,117,921
Ensembl chr12:52,110,718...52,117,783
JBrowse link
glutamate binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEP104 centrosomal protein 104 ISO RGD PMID:7488117 RGD:1299480 NCBI chr 6:65,274,092...65,310,735
Ensembl chr 6:65,274,486...65,310,728
JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 ISO RGD PMID:8663466 RGD:4144107 NCBI chr15:113,210,038...113,339,086
Ensembl chr15:113,209,999...113,339,078
JBrowse link
G GAD1 glutamate decarboxylase 1 ISO RGD PMID:10812196 RGD:6480261 NCBI chr15:76,991,863...77,034,819
Ensembl chr15:76,991,928...77,034,817
JBrowse link
G GAD2 glutamate decarboxylase 2 ISO RGD PMID:10812196 RGD:6480261 NCBI chr10:49,316,682...49,391,013
Ensembl chr10:49,313,641...49,390,926
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit enables IEA Ensembl GO_REF:0000107 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,564...27,253,535
JBrowse link
G GLUL glutamate-ammonia ligase ISO RGD PMID:28323 PMID:4403443 RGD:2301547 RGD:2301548 NCBI chr 9:123,751,551...123,762,575
Ensembl chr 9:123,751,548...123,762,547
JBrowse link
G GRIK1 glutamate ionotropic receptor kainate type subunit 1 ISO RGD PMID:12533604 PMID:16540562 RGD:1642470 RGD:1642497 NCBI chr13:192,877,707...193,296,954
Ensembl chr13:192,877,618...193,294,952
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 enables IEA Ensembl GO_REF:0000107
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A enables ISO PMID:9425000 RGD
UniProt
PMID:9425000 PMID:22098737 RGD:7241434 RGD:8554578 NCBI chr 3:32,749,329...33,149,350
Ensembl chr 3:32,752,351...33,143,499
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B enables ISO PMID:24876489 UniProt PMID:24876489 RGD:13432263 NCBI chr 5:58,477,862...58,948,735
Ensembl chr 5:58,480,526...58,927,583
JBrowse link
G GRIN2D glutamate ionotropic receptor NMDA type subunit 2D ISO RGD PMID:15107472 RGD:1642397 NCBI chr 6:53,809,590...53,849,535
Ensembl chr 6:53,806,174...53,847,788
JBrowse link
G GRM7 glutamate metabotropic receptor 7 enables ISO L-2-amino-4-phosphonobutyrate (L-AP4), glutamate analogue
(PMID:9144652)
RGD
UniProt
PMID:9144652 PMID:11825890 PMID:12692128 PMID:17620729 RGD:2289010 RGD:2289012 RGD:728749 NCBI chr13:63,318,002...64,203,982
Ensembl chr13:63,318,096...64,203,300
JBrowse link
G SLC1A1 solute carrier family 1 member 1 ISO RGD PMID:16128593 RGD:1599319 NCBI chr 1:217,366,493...217,441,643
Ensembl chr 1:217,366,499...217,441,674
JBrowse link
G SLC1A3 solute carrier family 1 member 3 enables IEA Ensembl GO_REF:0000107 NCBI chr16:21,873,691...21,965,315
Ensembl chr16:21,873,691...21,968,671
JBrowse link
glycine binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEP104 centrosomal protein 104 ISO RGD PMID:7488117 RGD:1299480 NCBI chr 6:65,274,092...65,310,735
Ensembl chr 6:65,274,486...65,310,728
JBrowse link
G GLDC glycine decarboxylase enables IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:6778858 PMID:21873635 RGD:1642728 NCBI chr 1:215,608,854...215,715,062
Ensembl chr 1:215,608,849...215,715,061
JBrowse link
G GLRA1 glycine receptor alpha 1 enables
contributes_to
ISO
IBA
(PMID:15748848), (PMID:2155780), (PMID:7920629), (PMID:8717357)
(MGI:69496|PMID:7874121)
(MGI:68467|PMID:8062927)
(MGI:1096078|PMID:9145798)
(PMID:21873635)
RGD
UniProt
MGI
GO_Central
PMID:2155780 PMID:7874121 PMID:7920629 PMID:8062927 PMID:8717357 More... MGI:1096078 MGI:68467 MGI:69496 RGD:1598572 NCBI chr16:71,140,751...71,236,867
Ensembl chr16:71,141,893...71,230,367
JBrowse link
G GLRA2 glycine receptor alpha 2 contributes_to
enables
IBA
IEA
(PMID:21873635) GO_Central
Ensembl
InterPro
PMID:21873635 GO_REF:0000002 GO_REF:0000107 NCBI chr  X:11,111,655...11,288,496
Ensembl chr  X:11,111,822...11,288,592
JBrowse link
G GLRA3 glycine receptor alpha 3 contributes_to
enables
IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr14:15,120,091...15,603,509
Ensembl chr14:15,303,538...15,595,028
JBrowse link
G GLRA4 glycine receptor alpha 4 contributes_to IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:84,584,907...84,612,860
Ensembl chr  X:84,584,907...84,612,860
JBrowse link
G GLRB glycine receptor beta contributes_to
enables
ISS
ISO
IBA
(MGI:55288|PMID:6285205), (MGI:56245|PMID:2983837)
(PMID:21873635)
UniProt
MGI
GO_Central
RGD
PMID:2983837 PMID:6285205 PMID:15574743 PMID:21873635 GO_REF:0000024 MGI:55288 MGI:56245 RGD:1598572 NCBI chr 8:45,912,869...46,034,455
Ensembl chr 8:45,912,938...46,034,448
JBrowse link
G GNMT glycine N-methyltransferase enables ISS
IBA
IEA
(PMID:21873635) UniProt
GO_Central
Ensembl
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:38,038,359...38,041,218
Ensembl chr 7:38,038,358...38,041,218
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 enables ISO
IEA
RGD
Ensembl
PMID:22098737 GO_REF:0000107 RGD:7241434
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B enables IEA Ensembl GO_REF:0000107 NCBI chr 5:58,477,862...58,948,735
Ensembl chr 5:58,480,526...58,927,583
JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A enables IEA Ensembl GO_REF:0000107 NCBI chr 1:243,263,202...243,416,739
Ensembl chr 1:243,259,493...243,415,590
JBrowse link
G GRIN3B glutamate ionotropic receptor NMDA type subunit 3B ISO RGD PMID:11823786 RGD:632842 NCBI chr 2:77,402,191...77,411,878
Ensembl chr 2:77,402,149...77,412,136
JBrowse link
G GSS glutathione synthetase ISO RGD PMID:10964706 RGD:1599340 NCBI chr17:38,316,199...38,342,253
Ensembl chr17:38,312,720...38,342,304
JBrowse link
L-DOPA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR143 G protein-coupled receptor 143 enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:6,242,296...6,276,654
NCBI chr  Y:4,669,764...4,704,304
JBrowse link
leucine binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLUD1 glutamate dehydrogenase 1 enables ISO (PMID:12742085) BHF-UCL PMID:12742085 NCBI chr14:87,968,850...88,005,375
Ensembl chr14:87,968,850...88,005,550
JBrowse link
G SESN1 sestrin 1 enables IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 1:75,056,731...75,170,374
Ensembl chr 1:75,033,098...75,169,987
JBrowse link
G SESN2 sestrin 2 enables IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 6:85,321,982...85,348,044
Ensembl chr 6:85,324,228...85,348,044
JBrowse link
G SESN3 sestrin 3 enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:27,207,239...27,279,205
Ensembl chr 9:27,207,236...27,298,628
JBrowse link
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:128,319,311...128,474,330
Ensembl chr 1:128,319,310...128,474,330
JBrowse link
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:37,655,808...37,785,301
Ensembl chr 7:37,655,847...37,784,359
JBrowse link
serine binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRM7 glutamate metabotropic receptor 7 enables IEA Ensembl GO_REF:0000107 NCBI chr13:63,318,002...64,203,982
Ensembl chr13:63,318,096...64,203,300
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 enables IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,414,446...60,435,450
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,321
JBrowse link
G THNSL2 threonine synthase like 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:57,800,976...57,821,296
Ensembl chr 3:57,799,026...57,823,440
JBrowse link
tyrosine binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR143 G protein-coupled receptor 143 enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:6,242,296...6,276,654
NCBI chr  Y:4,669,764...4,704,304
JBrowse link
G YARS2 tyrosyl-tRNA synthetase 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:41,561,563...41,584,534
Ensembl chr 5:41,561,626...41,584,818
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17491
    binding 15409
      small molecule binding 2268
        organic acid binding 157
          amino acid binding 70
            3-sulfino-L-alanine binding 0
            L-DOPA binding 1
            L-cysteine binding 0
            arginine binding 8
            aspartate binding 0
            glutamate binding 14
            glycine binding 13
            leucine binding 6
            proline binding 0
            serine binding 4
            tryptophan binding + 0
            tyrosine binding + 2
paths to the root