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ONTOLOGY REPORT - ANNOTATIONS

Term:protein processing
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Accession:GO:0016485 term browser browse the term
Definition:Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
Synonyms:exact_synonym: protein maturation by peptide bond cleavage;   protein maturation by peptide bond hydrolysis
 related_synonym: peptidolysis during protein maturation;   protein maturation by proteolysis
 alt_id: GO:0051605


show annotations for term's descendants           Sort by:
protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Actmap actin maturation protease involved_in ISO (PMID:36173861) RGD PMID:36173861 NCBI chr 1:82,490,313...82,499,841
Ensembl chr 1:82,490,363...82,499,841 		JBrowse link
G Adam10 ADAM metallopeptidase domain 10 acts_upstream_of_or_within ISO (PMID:20383322) RGD PMID:20383322 NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA		 (PMID:9774383)
GO_REF:0000107		 RGD
Ensembl		 PMID:9774383 GO_REF:0000107 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adam19 ADAM metallopeptidase domain 19 involved_in ISO (PMID:17112471) RGD PMID:17112471 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 involved_in ISO (PMID:12054541) RGD PMID:12054541 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 acts_upstream_of_or_within ISO MGI:2388161 (PMID:16556917) RGD PMID:16556917 NCBI chr10:34,920,992...35,126,465
Ensembl chr10:34,921,049...35,123,821 		JBrowse link
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:11408482), (PMID:24552833)
(PMID:16556917)		 RGD PMID:11408482 PMID:16556917 PMID:24552833 NCBI chr14:18,231,128...18,437,771
Ensembl chr14:18,231,165...18,435,556 		JBrowse link
G Aebp1 AE binding protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877 		JBrowse link
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 involved_in ISO (PMID:19656850) RGD PMID:19656850 NCBI chr18:60,954,268...60,999,110
Ensembl chr18:60,954,268...60,999,110 		JBrowse link
G Anpep alanyl aminopeptidase, membrane IDA RGD PMID:16537183 RGD:1581649 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit involved_in ISO
IBA		 UniProtKB:P05067|UniProtKB:P49768 (PMID:12297508), (PMID:12763021), (PMID:15274632), (PMID:27608597)
GO_REF:0000033		 RGD
GO_Central		 PMID:12297508 PMID:12763021 PMID:15274632 PMID:27608597 GO_REF:0000033 NCBI chr 2:183,437,676...183,443,113
Ensembl chr 2:183,438,434...183,441,955 		JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit involved_in
acts_upstream_of_or_within		 ISO
IBA		 UniProtKB:P05067|UniProtKB:P49768 (PMID:12763021), (PMID:27608597)
GO_REF:0000033
(PMID:12297508)		 RGD
GO_Central		 PMID:12297508 PMID:12763021 PMID:27608597 GO_REF:0000033 NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243 		JBrowse link
G Aph1bl2 aph-1 homolog B, gamma secretase subunit like 2 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:67,341,790...67,363,967
Ensembl chr 8:67,341,834...67,363,864
Ensembl chr 8:67,341,834...67,363,864 		JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 involved_in ISO (PMID:16098038)
(PMID:16837463)		 RGD PMID:16098038 PMID:16837463 NCBI chr 4:119,077,415...119,078,887
Ensembl chr 4:119,077,356...119,078,379 		JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:104,665,345...104,765,271
Ensembl chr  X:104,665,345...104,765,268 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103 		JBrowse link
G Atg4c autophagy related 4C, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:113,867,218...113,935,534
Ensembl chr 5:113,867,092...113,934,830 		JBrowse link
G Atg4d autophagy related 4D, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:19,807,733...19,817,321
Ensembl chr 8:19,807,766...19,817,321 		JBrowse link
G Bace1 beta-secretase 1 involved_in ISO (PMID:10531052) RGD PMID:10531052 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bace2 beta-secretase 2 involved_in ISO (PMID:23754390) RGD PMID:23754390 NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G Bmp1 bone morphogenetic protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776 		JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator acts_upstream_of_or_within ISO (PMID:19004860) RGD PMID:19004860 NCBI chr 1:154,715,151...154,812,955
Ensembl chr 1:154,715,310...154,812,520 		JBrowse link
G Casp1 caspase 1 acts_upstream_of_or_within ISO MGI:1927822 (PMID:11016935), (PMID:14663141), (PMID:15190255), (PMID:16301672) RGD PMID:11016935 PMID:14663141 PMID:15190255 PMID:16301672 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp2 caspase 2 involved_in ISO (PMID:9044836) RGD PMID:9044836 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:9334240)
(PMID:15231831)		 RGD PMID:9334240 PMID:15231831 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 acts_upstream_of_or_within ISO (PMID:15231831) RGD PMID:15231831 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 involved_in IDA
ISO
ISS		 (PMID:30361383)
GO_REF:0000024		 RGD
UniProt		 PMID:30361383 PMID:16493077 GO_REF:0000024, RGD:4143200 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 IDA RGD PMID:18316105 RGD:2311460 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within ISO MGI:2388887 (PMID:15588329) RGD PMID:15588329 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434 		JBrowse link
G Cma1 chymase 1 IDA RGD PMID:15869764 RGD:1581745 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233 		JBrowse link
G Cntn2 contactin 2 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:18278038)
GO_REF:0000107		 RGD
Ensembl		 PMID:18278038 GO_REF:0000107 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887 		JBrowse link
G Comp cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180787 (PMID:26045608)		 Ensembl
RGD		 PMID:26045608 GO_REF:0000107 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Cpd carboxypeptidase D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491 		JBrowse link
G Cpe carboxypeptidase E involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:2822027 GO_REF:0000033, RGD:1626225 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Cplane2 ciliogenesis and planar polarity effector complex subunit 2 acts_upstream_of_or_within ISO MGI:6887373 (PMID:29038301) RGD PMID:29038301 NCBI chr 5:153,515,507...153,516,455
Ensembl chr 5:153,515,376...153,522,508 		JBrowse link
G Cpm carboxypeptidase M involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220 		JBrowse link
G Cpn1 carboxypeptidase N subunit 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465 		JBrowse link
G Cpz carboxypeptidase Z involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945 		JBrowse link
G Ctsg cathepsin G involved_in ISO
IEA
ISS		 (PMID:16963625), (PMID:22879591), (PMID:30804664), (PMID:7744748)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:7744748 PMID:16963625 PMID:22879591 PMID:30804664 GO_REF:0000024 GO_REF:0000107 NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353 		JBrowse link
G Ctss cathepsin S involved_in ISO
IEA		 (PMID:22864553)
GO_REF:0000107		 RGD
Ensembl		 PMID:22864553 GO_REF:0000107 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Ddi2 DNA damage inducible 1 homolog 2 involved_in ISO (PMID:27528193), (PMID:27676298) RGD PMID:27528193 PMID:27676298 NCBI chr 5:153,989,591...154,035,342
Ensembl chr 5:153,995,589...154,035,283 		JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3578144 (PMID:16061793), (PMID:16229832)		 Ensembl
RGD		 PMID:16061793 PMID:16229832 GO_REF:0000107 NCBI chr 8:4,189,067...4,412,183
Ensembl chr 8:4,189,257...4,412,183 		JBrowse link
G Ece1 endothelin converting enzyme 1 involved_in IDA
ISO		 (PMID:7805846) RGD PMID:7805846 PMID:8034569 RGD:728596 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Ece2 endothelin-converting enzyme 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:80,259,130...80,278,446
Ensembl chr11:80,263,162...80,278,428 		JBrowse link
G Ecel1 endothelin converting enzyme-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:87,819,516...87,829,154
Ensembl chr 9:87,816,718...87,826,675 		JBrowse link
G Enpep glutamyl aminopeptidase IDA RGD PMID:16537183 RGD:1581649 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947 		JBrowse link
G F12 coagulation factor XII involved_in ISO (PMID:18725990) RGD PMID:18725990 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G F3 coagulation factor III, tissue factor involved_in ISO (PMID:24998411) RGD PMID:24998411 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G F7 coagulation factor VII involved_in ISO (PMID:24998411) RGD PMID:24998411 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G Fkrp fukutin related protein acts_upstream_of_or_within ISO (PMID:12471058) RGD PMID:12471058 NCBI chr 1:77,479,641...77,486,954
Ensembl chr 1:77,476,084...77,486,992 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) acts_upstream_of_or_within
involved_in		 IDA
ISO
IMP		 MGI:3700008 (PMID:20530870), (PMID:21147780), (PMID:23918928)
(PMID:15606899)
(PMID:10526337), (PMID:10567353), (PMID:14744861), (PMID:15899807), (PMID:17938254), (PMID:9242664)		 RGD PMID:9242664 PMID:10526337 PMID:10567353 PMID:14744861 PMID:15606899 More... RGD:633598, RGD:1582619 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:4829764|MGI:97513 (PMID:20530870)		 Ensembl
RGD		 PMID:20530870 GO_REF:0000107 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO (PMID:19036983) RGD PMID:19036983 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Ift172 intraflagellar transport 172 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2682066 (PMID:16061793)		 Ensembl
RGD		 PMID:16061793 GO_REF:0000107 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:23395675)		 Ensembl
RGD		 PMID:23395675 GO_REF:0000107 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Kel Kell metallo-endopeptidase (Kell blood group) involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:70,568,241...70,585,666
Ensembl chr 4:70,568,243...70,585,631 		JBrowse link
G Klk13 kallikrein related-peptidase 13 acts_upstream_of_or_within ISO (PMID:16423834) RGD PMID:16423834 NCBI chr 1:94,165,381...94,177,002
Ensembl chr 1:94,165,381...94,177,002 		JBrowse link
G Lonp2 lon peptidase 2, peroxisomal involved_in ISO
IBA
IEA		 (PMID:18281296)
GO_REF:0000033
GO_REF:0000104		 RGD
GO_Central
UniProt		 PMID:18281296 GO_REF:0000033 GO_REF:0000104 NCBI chr19:20,407,475...20,498,985
Ensembl chr19:20,407,477...20,499,014 		JBrowse link
G Mafb MAF bZIP transcription factor B involved_in ISO MGI:3663168 (PMID:27208706) RGD PMID:27208706 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031 		JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:34349020)		 UniProt
Ensembl
RGD		 PMID:34349020 GO_REF:0000024 GO_REF:0000107 NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791 		JBrowse link
G Metap2 methionyl aminopeptidase 2 involved_in ISO
ISS		 (PMID:8858118)
GO_REF:0000024		 RGD
HGNC-UCL		 PMID:8858118 GO_REF:0000024 NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434 		JBrowse link
G Mme membrane metallo-endopeptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
G Mmel1 membrane metallo-endopeptidase-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:165,431,278...165,461,716
Ensembl chr 5:165,431,343...165,461,716 		JBrowse link
G Mmp16 matrix metallopeptidase 16 involved_in ISO
IEA		 (PMID:27229514)
GO_REF:0000107		 RGD
Ensembl		 PMID:27229514 GO_REF:0000107 NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:1931143 (PMID:12970677) RGD PMID:12970677 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (PMID:18325808) RGD PMID:18325808 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Ncstn nicastrin involved_in IEP
IBA
IEA
ISS
ISO		 GO_REF:0000033
GO_REF:0000002
GO_REF:0000024
UniProtKB:P05067|UniProtKB:P49768 (PMID:12297508), (PMID:12763021), (PMID:15274632), (PMID:27608597)		 GO_Central
InterPro
UniProt
RGD		 PMID:12297508 PMID:12763021 PMID:15274632 PMID:27608597 PMID:12736250 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033, RGD:724403 NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:28584052)		 UniProt
Ensembl
RGD		 PMID:28584052 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (PMID:11016935) RGD PMID:11016935 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO		 GO_REF:0000024
(PMID:28288130)		 UniProt
RGD		 PMID:28288130 GO_REF:0000024 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 involved_in IMP
ISO		 (PMID:9242664) RGD PMID:9242664 PMID:16497799 RGD:1601276 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 involved_in IMP
ISO		 (PMID:9242664) RGD PMID:9242664 PMID:16497799 RGD:1601276 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
G Pcsk4 proprotein convertase subtilisin/kexin type 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:16040806)		 UniProt
Ensembl
RGD		 PMID:16040806 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:9,381,366...9,389,589
Ensembl chr 7:9,381,361...9,389,585 		JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 involved_in
acts_upstream_of_or_within		 ISO (PMID:8901832)
(PMID:18519639), (PMID:8468318), (PMID:9242664)
(PMID:21147780)
(PMID:15606899)		 RGD PMID:8468318 PMID:8901832 PMID:9242664 PMID:15606899 PMID:18519639 More... NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 involved_in
acts_upstream_of_or_within		 ISO (PMID:8218226), (PMID:9242664), (PMID:9738469)
(PMID:23918928)		 RGD PMID:8218226 PMID:9242664 PMID:9738469 PMID:23918928 NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596 		JBrowse link
G Pcsk7 proprotein convertase subtilisin/kexin type 7 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:15606899)
GO_REF:0000033		 RGD
GO_Central		 PMID:15606899 GO_REF:0000033 NCBI chr 8:46,202,079...46,224,699
Ensembl chr 8:46,202,131...46,224,705 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 IDA RGD PMID:14622975 RGD:1582518 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
G Phex phosphate regulating endopeptidase X-linked involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:37,607,553...37,856,183
Ensembl chr  X:37,610,760...37,854,469 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 IMP RGD PMID:11171063 RGD:628447 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048 		JBrowse link
G Pitrm1 pitrilysin metallopeptidase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:63,795,670...63,827,317
Ensembl chr17:63,795,671...63,839,907 		JBrowse link
G Plg plasminogen acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:34380733)
GO_REF:0000107		 RGD
Ensembl		 PMID:34380733 GO_REF:0000107 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
G Pmpca peptidase, mitochondrial processing subunit alpha IDA RGD PMID:2236012 RGD:1299588 NCBI chr 3:9,207,731...9,216,846
Ensembl chr 3:9,207,717...9,216,844 		JBrowse link
G Pmpcb peptidase, mitochondrial processing subunit beta involved_in IDA PMID:10942759 UniProt PMID:10942759 RGD:38501073 NCBI chr 4:13,297,583...13,310,363
Ensembl chr 4:13,297,559...13,310,367 		JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma acts_upstream_of_or_within ISO (PMID:12297508) RGD PMID:12297508 NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346 		JBrowse link
G Psen1 presenilin 1 involved_in
acts_upstream_of_or_within		 IDA
IBA
ISO
ISS		 GO_REF:0000033
MGI:2149116|MGI:2179062|MGI:2449304 (PMID:10206645), (PMID:11567612)
UniProtKB:P05067 (PMID:12297508), (PMID:12763021), (PMID:15274632), (PMID:27608597)
GO_REF:0000024		 GO_Central
RGD
UniProt		 PMID:10206645 PMID:11567612 PMID:12297508 PMID:12763021 PMID:15274632 More... GO_REF:0000024 GO_REF:0000033, RGD:1358417 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:15274632), (PMID:27608597)
GO_REF:0000033
MGI:1202717 (PMID:15280425)		 RGD
GO_Central		 PMID:15274632 PMID:15280425 PMID:27608597 GO_REF:0000033 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Psenen presenilin enhancer gamma secretase subunit involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (PMID:12522139), (PMID:12660785), (PMID:12763021), (PMID:15274632) RGD PMID:12522139 PMID:12660785 PMID:12763021 PMID:15274632 NCBI chr 1:85,814,905...85,816,654
Ensembl chr 1:85,814,905...85,816,192 		JBrowse link
G Ptch1 patched 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857447 (PMID:16061793)		 UniProt
RGD		 PMID:16061793 GO_REF:0000024 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO (PMID:17328886) RGD PMID:17328886 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Rnpep arginyl aminopeptidase involved_in IDA
NAS		 PMID:9405297 RGD
UniProt		 PMID:16537183 PMID:9405297 RGD:1581649, RGD:2325944 NCBI chr13:46,699,458...46,717,829
Ensembl chr13:46,699,463...46,717,998 		JBrowse link
G Sde2 SDE2 telomere maintenance homolog involved_in ISO
IEA		 (PMID:27906959)
GO_REF:0000107		 RGD
Ensembl		 PMID:27906959 GO_REF:0000107 NCBI chr13:92,578,843...92,595,142
Ensembl chr13:92,578,874...92,595,140 		JBrowse link
G Spon1 spondin 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:16227578)		 Ensembl
RGD		 PMID:16227578 GO_REF:0000107 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226 		JBrowse link
G Srgn serglycin involved_in ISS
ISO		 GO_REF:0000024
(PMID:17081126)		 UniProt
RGD		 PMID:17081126 GO_REF:0000024 NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406 		JBrowse link
G Tll1 tolloid-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:25,509,146...25,710,330
Ensembl chr16:25,509,146...25,709,543 		JBrowse link
G Tll2 tolloid-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:239,912,648...240,028,168
Ensembl chr 1:239,915,508...240,028,120 		JBrowse link
G Tmprss12 transmembrane serine protease 12 acts_upstream_of_or_within ISO MGI:6455010 (PMID:32529245) RGD PMID:32529245 NCBI chr 7:131,433,158...131,445,806
Ensembl chr 7:131,433,484...131,445,791 		JBrowse link
G Tmprss4 transmembrane serine protease 4 involved_in ISO (PMID:24434139) RGD PMID:24434139 NCBI chr 8:45,475,819...45,508,409
Ensembl chr 8:45,476,053...45,508,409 		JBrowse link
G Tysnd1 trypsin like peroxisomal matrix peptidase 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:22002062)		 UniProt
GO_Central
RGD		 PMID:22002062 GO_REF:0000024 GO_REF:0000033 NCBI chr20:29,637,942...29,646,492
Ensembl chr20:29,638,277...29,643,995 		JBrowse link
G Xpnpep3 X-prolyl aminopeptidase 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20179356)
GO_REF:0000107		 RGD
Ensembl		 PMID:20179356 GO_REF:0000107 NCBI chr 7:112,926,154...112,978,793
Ensembl chr 7:112,926,248...112,974,878 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (PMID:11923874) RGD PMID:11923874 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
activation of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asph aspartate-beta-hydroxylase involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Casp8 caspase 8 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113 		JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Lgmn legumain involved_in ISO (PMID:9821970) RGD PMID:9821970 NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISO UniProtKB:P10749|UniProtKB:P29466 (PMID:15882992) RGD PMID:15882992 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 acts_upstream_of_or_within ISO (PMID:30248149) RGD PMID:30248149 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Perp p53 apoptosis effector related to PMP22 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:23302887) RGD PMID:23302887 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in ISO (PMID:11821383) RGD PMID:11821383 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Tbc1d10a TBC1 domain family, member 10a involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr14:79,051,822...79,083,603
Ensembl chr14:79,055,432...79,083,600 		JBrowse link
activation of plasma proteins involved in acute inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor involved_in ISO (PMID:17469850) RGD PMID:17469850 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
angiotensin maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:11303049), (PMID:14757757), (PMID:18158355), (PMID:27649628)
(PMID:11432860), (PMID:1320019), (PMID:4322742), (PMID:6270633)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:1320019 PMID:4322742 PMID:6270633 PMID:11303049 PMID:11432860 More... GO_REF:0000024 GO_REF:0000107 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 involved_in ISO UniProtKB:Q9BYF1 (PMID:18263657), (PMID:20357030), (PMID:23462816) RGD PMID:18263657 PMID:20357030 PMID:23462816 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Anpep alanyl aminopeptidase, membrane involved_in ISO (PMID:8876246) RGD PMID:8876246 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO
IEA		 (PMID:12045255), (PMID:15746149)
GO_REF:0000107		 RGD
Ensembl		 PMID:12045255 PMID:15746149 GO_REF:0000107 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Cpa3 carboxypeptidase A3 involved_in ISO (PMID:15173164) RGD PMID:15173164 NCBI chr 2:102,712,483...102,744,219
Ensembl chr 2:102,712,589...102,744,203 		JBrowse link
G Enpep glutamyl aminopeptidase involved_in ISO MGI:2182774 (PMID:16889841), (PMID:19228697) RGD PMID:16889841 PMID:19228697 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947 		JBrowse link
G Mme membrane metallo-endopeptidase involved_in ISO MGI:1917258|MGI:2137696 (PMID:27649628), (PMID:28559246) RGD PMID:27649628 PMID:28559246 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
G Prcp prolylcarboxypeptidase involved_in ISO (PMID:27649628) RGD PMID:27649628 NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530 		JBrowse link
G Prep prolyl endopeptidase involved_in ISO (PMID:27649628) RGD PMID:27649628 NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466 		JBrowse link
G Ren renin involved_in
acts_upstream_of_or_within		 IDA
ISO
IBA		 (PMID:27649628), (PMID:6337154)
MGI:2136642 (PMID:10617578)
GO_REF:0000033
(PMID:12045255)		 RGD
GO_Central		 PMID:6337154 PMID:10617578 PMID:12045255 PMID:27649628 PMID:21321306 GO_REF:0000033, RGD:5132599 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
CAAX-box protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rce1 Ras converting CAAX endopeptidase 1 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
(PMID:10085068), (PMID:19188362)		 UniProt
GO_Central
Ensembl
InterPro
RGD		 PMID:10085068 PMID:19188362 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:201,899,358...201,902,593
Ensembl chr 1:201,899,358...201,902,484 		JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:19188362) RGD PMID:19188362 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
cytokine precursor processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 involved_in ISO UniProtKB:P10749|UniProtKB:Q9NPP4 (PMID:15882992) RGD PMID:15882992 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Cma1 chymase 1 involved_in ISO (PMID:1919436) RGD PMID:1919436 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO
ISS
IEA		 (PMID:7737999)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:7737999 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18519639)		 Ensembl
RGD		 PMID:18519639 GO_REF:0000107 NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600 		JBrowse link
dibasic protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO
IEA		 (PMID:11799113)
GO_REF:0000107		 RGD
Ensembl		 PMID:11799113 GO_REF:0000107 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
endothelin maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ece1 endothelin converting enzyme 1 involved_in ISO
IEA		 (PMID:7805846)
GO_REF:0000107		 RGD
Ensembl		 PMID:7805846 GO_REF:0000107 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
enkephalin processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpe carboxypeptidase E IDA RGD PMID:6326144 RGD:6483103 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Ctsl cathepsin L involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 involved_in ISO (PMID:8262946) RGD PMID:8262946 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
epidermal growth factor receptor ligand maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 involved_in IEA
ISO		 GO_REF:0000107
(PMID:14993236), (PMID:17079736)		 Ensembl
RGD		 PMID:14993236 PMID:17079736 GO_REF:0000107 NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889 		JBrowse link
G Mep1a meprin A subunit alpha involved_in ISO (PMID:22923609) RGD PMID:22923609 NCBI chr 9:17,474,634...17,504,147
Ensembl chr 9:17,474,619...17,504,147 		JBrowse link
Factor XII activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII involved_in ISO
IEA		 (PMID:18725990)
GO_REF:0000107		 RGD
Ensembl		 PMID:18725990 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Kng2 kininogen 2 IDA RGD PMID:6685967 RGD:11062094 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971 		JBrowse link
inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin involved_in ISO (PMID:2407243) RGD PMID:2407243 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cst7 cystatin F acts_upstream_of_or_within ISO MGI:5910746 (PMID:28251676) RGD PMID:28251676 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP PMID:16639714 UniProt PMID:16639714 RGD:10047164 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
insulin processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpe carboxypeptidase E involved_in
acts_upstream_of_or_within		 IDA
IMP
ISO
IEA		 MGI:1856395 (PMID:9348219)
MGI:1856395 (PMID:7663508)
GO_REF:0000107		 RGD
Ensembl		 PMID:7663508 PMID:9348219 PMID:2822027 PMID:12829804 GO_REF:0000107, RGD:1626225, RGD:405650689 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta acts_upstream_of_or_within
involved_in		 ISO MGI:3864866 (PMID:20308425) RGD PMID:20308425 NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398 		JBrowse link
G Ins2 insulin 2 involved_in IEA
ISO		 GO_REF:0000107
MGI:2442682 (PMID:20424817)		 Ensembl
RGD		 PMID:20424817 GO_REF:0000107 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta involved_in ISO MGI:5504624 (PMID:31184304) RGD PMID:31184304 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 involved_in ISO MGI:2384741 (PMID:12136131) RGD PMID:12136131 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 involved_in ISO (PMID:7626024)
MGI:1857445 (PMID:9452465)		 RGD PMID:7626024 PMID:9452465 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
G Slc30a8 solute carrier family 30 member 8 involved_in ISO MGI:4362061 (PMID:19542200), (PMID:19706465) RGD PMID:19542200 PMID:19706465 NCBI chr 7:83,591,993...83,627,786
Ensembl chr 7:83,591,993...83,626,305 		JBrowse link
G Yipf5 Yip1 domain family, member 5 involved_in ISO
ISS		 (PMID:33164986)
GO_REF:0000024		 RGD
UniProt		 PMID:33164986 GO_REF:0000024 NCBI chr18:32,123,814...32,136,947
Ensembl chr18:32,123,842...32,157,642 		JBrowse link
intein-mediated protein splicing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhh desert hedgehog signaling molecule involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
islet amyloid polypeptide processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcsk2 proprotein convertase subtilisin/kexin type 2 involved_in IMP PMID:15983213 BHF-UCL PMID:15983213 RGD:8554260 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
mitochondrial protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afg3l1 AFG3 (ATPase family gene 3)-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:51,508,612...51,535,773
Ensembl chr19:51,508,613...51,537,396 		JBrowse link
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1928277 (PMID:19656850), (PMID:20038678)		 GO_Central
RGD		 PMID:19656850 PMID:20038678 GO_REF:0000033 NCBI chr18:60,954,268...60,999,110
Ensembl chr18:60,954,268...60,999,110 		JBrowse link
G Atp23 ATP23 metallopeptidase and ATP synthase assembly factor homolog involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:62,714,752...62,729,893
Ensembl chr 7:62,714,785...62,729,862 		JBrowse link
G Oma1 OMA1 zinc metallopeptidase involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:24550258), (PMID:24719224)
(PMID:20038678)
GO_REF:0000033
GO_REF:0000107
(PMID:25275009), (PMID:25605331)		 UniProt
RGD
GO_Central
Ensembl		 PMID:20038678 PMID:24550258 PMID:24719224 PMID:25275009 PMID:25605331 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:118,083,728...118,136,980
Ensembl chr 5:118,083,728...118,136,980 		JBrowse link
G Spg7 SPG7 matrix AAA peptidase subunit, paraplegin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:51,117,088...51,151,228
Ensembl chr19:51,117,057...51,150,484 		JBrowse link
G Stoml2 stomatin like 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19360003)		 UniProt
RGD		 PMID:19360003 GO_REF:0000024 NCBI chr 5:57,256,227...57,259,824
Ensembl chr 5:57,256,220...57,259,920 		JBrowse link
G Yme1l1 YME1-like 1 ATPase involved_in ISO
IEA
ISS		 (PMID:27495975)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:27495975 GO_REF:0000024 GO_REF:0000107 NCBI chr17:85,287,607...85,326,068
Ensembl chr17:85,287,554...85,326,335 		JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpb2 carboxypeptidase B2 IMP RGD PMID:23369837 RGD:7243115 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556 		JBrowse link
G Ctsz cathepsin Z involved_in ISO
IEA		 (PMID:19433310)
GO_REF:0000107		 RGD
Ensembl		 PMID:19433310 GO_REF:0000107 NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645 		JBrowse link
G Serpine1 serpin family E member 1 involved_in IEA
ISO
IBA		 GO_REF:0000107
(PMID:19855083)
GO_REF:0000033
(PMID:18835034), (PMID:19855083), (PMID:8508955)		 Ensembl
RGD
GO_Central		 PMID:8508955 PMID:18835034 PMID:19855083 GO_REF:0000033 GO_REF:0000107 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IBA
IEA		 (PMID:19855083)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:19855083 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:134998) RGD PMID:134998 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp4 acid phosphatase 4 involved_in ISO (PMID:15219672) RGD PMID:15219672 NCBI chr 1:94,736,376...94,751,871
Ensembl chr 1:94,735,514...94,744,623 		JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (PMID:17344476) RGD PMID:17344476 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 involved_in ISO
ISS		 (PMID:22445366)
GO_REF:0000024		 RGD
UniProt		 PMID:22445366 GO_REF:0000024 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IMP Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (PMID:21357679) RGD PMID:21357679 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4829764|MGI:97513 (PMID:20530870)		 Ensembl
RGD		 PMID:20530870 GO_REF:0000107 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:23395675)		 Ensembl
RGD		 PMID:23395675 GO_REF:0000107 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21370995) RGD PMID:21370995 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IMP Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Snx12 sorting nexin 12 involved_in ISO (PMID:22709416) RGD PMID:22709416 NCBI chr  X:66,226,995...66,356,945
Ensembl chr  X:66,227,053...66,356,950 		JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:30249802)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:30249802 GO_REF:0000024 GO_REF:0000107 NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079 		JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:19188362) RGD PMID:19188362 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 IMP RGD PMID:24029877 RGD:9586053 NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439 		JBrowse link
neuropeptide processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mme membrane metallo-endopeptidase involved_in ISO
IEA		 UniProtKB:P05067 (PMID:24825898)
GO_REF:0000107		 RGD
Ensembl		 PMID:24825898 GO_REF:0000107 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
patched ligand maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Disp1 dispatched RND transporter family member 1 acts_upstream_of_or_within ISO MGI:2429759 (PMID:12421714) RGD PMID:12421714 NCBI chr13:94,720,928...94,866,695
Ensembl chr13:94,720,928...94,866,702 		JBrowse link
peptide hormone processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Corin corin, serine peptidase involved_in ISO
IEA
ISS		 (PMID:10880574)
(PMID:11884416), (PMID:15637153), (PMID:22437503)
GO_REF:0000002
(PMID:21518754)
GO_REF:0000024
GO_REF:0000107		 RGD
InterPro
UniProt
Ensembl		 PMID:10880574 PMID:11884416 PMID:15637153 PMID:21518754 PMID:22437503 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503 		JBrowse link
G Cpe carboxypeptidase E TAS RGD PMID:2784437 RGD:727682 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Ece1 endothelin converting enzyme 1 involved_in ISO
IBA		 (PMID:7864876)
GO_REF:0000033		 RGD
GO_Central		 PMID:7864876 GO_REF:0000033 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Ece2 endothelin-converting enzyme 2 involved_in TAS
ISO		 (PMID:11718899) RGD PMID:11718899 PMID:15060002 RGD:1303943 NCBI chr11:80,259,130...80,278,446
Ensembl chr11:80,263,162...80,278,428 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO
IBA
IEA		 (PMID:9242664)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:9242664 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 involved_in IMP
ISO
IBA
IDA		 (PMID:8262946), (PMID:9242664)
GO_REF:0000033
pituitary adenylate cyclase-activating polypetide		 RGD
GO_Central		 PMID:8262946 PMID:9242664 PMID:16497799 PMID:10087454 GO_REF:0000033, RGD:1601276, RGD:2308913 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434 		JBrowse link
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:10632593)		 Ensembl
RGD		 PMID:10632593 GO_REF:0000107 NCBI chr  X:14,580,036...14,583,478
Ensembl chr  X:14,580,038...14,583,566 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 involved_in
acts_upstream_of_or_within		 IMP
ISO
IBA
ISS		 (PMID:9242664)
MGI:1857445 (PMID:12859669)
GO_REF:0000033
GO_REF:0000024
(PMID:28719828)		 RGD
GO_Central
UniProt		 PMID:9242664 PMID:12859669 PMID:28719828 PMID:16497799 GO_REF:0000024 GO_REF:0000033, RGD:1601276 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
G Pcsk4 proprotein convertase subtilisin/kexin type 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:9,381,366...9,389,589
Ensembl chr 7:9,381,361...9,389,585 		JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 involved_in ISO
IBA
IEA		 (PMID:8901832)
(PMID:18519639), (PMID:8468318), (PMID:9242664)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:8468318 PMID:8901832 PMID:9242664 PMID:18519639 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 involved_in IEP
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:9242664)		 GO_Central
Ensembl
RGD		 PMID:9242664 PMID:8070361 GO_REF:0000033 GO_REF:0000107, RGD:729476 NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596 		JBrowse link
G Scg5 secretogranin V involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:10089884)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:10089884 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:100,544,101...100,588,558
Ensembl chr 3:100,544,099...100,588,463 		JBrowse link
plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO
IEA		 (PMID:16480936)
GO_REF:0000107		 RGD
Ensembl		 PMID:16480936 GO_REF:0000107 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase acts_upstream_of_or_within ISO MGI:3027024 (PMID:16407971) RGD PMID:16407971 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G F11 coagulation factor XI involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G H2bc1 H2B clustered histone 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:17690254)		 Ensembl
RGD		 PMID:17690254 GO_REF:0000107 NCBI chr17:41,172,041...41,172,510
Ensembl chr17:41,171,903...41,176,782
Ensembl chr17:41,171,903...41,176,782 		JBrowse link
G Klkb1 kallikrein B1 involved_in ISO
IEA		 (PMID:89876)
GO_REF:0000107		 RGD
Ensembl		 PMID:89876 GO_REF:0000107 NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 involved_in ISO (PMID:11130727) RGD PMID:11130727 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Plat plasminogen activator, tissue type involved_in IDA
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
(PMID:12694198), (PMID:17849409), (PMID:24196407)		 GO_Central
Ensembl
InterPro
RGD		 PMID:12694198 PMID:17849409 PMID:24196407 PMID:8343497 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:11537479 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase involved_in ISO
IEA
IBA		 (PMID:25978044)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:25978044 GO_REF:0000033 GO_REF:0000107 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Tmprss9 transmembrane serine protease 9 acts_upstream_of_or_within ISO (PMID:16872279) RGD PMID:16872279 NCBI chr 7:8,810,321...8,831,177
Ensembl chr 7:8,810,320...8,831,177 		JBrowse link
positive regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:9836589) RGD PMID:9836589 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Clec3b C-type lectin domain family 3, member B involved_in ISS
ISO		 GO_REF:0000024
(PMID:12694198)		 UniProt
RGD		 PMID:12694198 GO_REF:0000024 NCBI chr 8:122,810,120...122,815,837
Ensembl chr 8:122,810,149...122,815,835 		JBrowse link
G Eno1 enolase 1 involved_in ISO (PMID:12666133) RGD PMID:12666133 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336 		JBrowse link
G F12 coagulation factor XII involved_in ISO
IEA		 (PMID:89876)
GO_REF:0000107		 RGD
Ensembl		 PMID:89876 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Hpn hepsin involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:16908524)		 UniProt
Ensembl
RGD		 PMID:16908524 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Meltf melanotransferrin involved_in ISO (PMID:16713448) RGD PMID:16713448 NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300 		JBrowse link
G Plgrkt plasminogen receptor with a C-terminal lysine involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:19897580)		 GO_Central
RGD		 PMID:19897580 GO_REF:0000033 NCBI chr 1:227,099,005...227,111,277
Ensembl chr 1:227,099,015...227,111,194 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 IDA RGD PMID:11027681 RGD:67924 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384 		JBrowse link
G S100a10 S100 calcium binding protein A10 involved_in ISO
IEA		 (PMID:9836589)
GO_REF:0000107		 RGD
Ensembl		 PMID:9836589 GO_REF:0000107 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661 		JBrowse link
positive regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl8 angiopoietin-like 8 acts_upstream_of_or_within ISO (PMID:23150577) RGD PMID:23150577 NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490 		JBrowse link
G Astl astacin like metalloendopeptidase involved_in ISO (PMID:22472438) RGD PMID:22472438 NCBI chr 3:114,563,135...114,580,295
Ensembl chr 3:114,563,135...114,578,868 		JBrowse link
G Bag2 BAG cochaperone 2 involved_in ISO (PMID:16207813) RGD PMID:16207813 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721 		JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 involved_in ISO (PMID:24552833) RGD PMID:24552833 NCBI chr18:59,579,851...59,823,977
Ensembl chr18:59,580,768...59,824,400 		JBrowse link
G Cntn2 contactin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18278038)
GO_REF:0000107		 RGD
Ensembl		 PMID:18278038 GO_REF:0000107 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887 		JBrowse link
G Ctnnd1 catenin delta 1 acts_upstream_of_or_within ISO MGI:98397 (PMID:17344476) RGD PMID:17344476 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516 		JBrowse link
G Fuz fuzzy planar cell polarity protein acts_upstream_of_or_within ISO MGI:4346364 (PMID:19877275) RGD PMID:19877275 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530 		JBrowse link
G Mbl2 mannose binding lectin 2 IDA Masp2 RGD PMID:20118239 RGD:7242176 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mmp14 matrix metallopeptidase 14 IMP RGD PMID:14668206 RGD:1582606 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 involved_in ISO (PMID:15064403) RGD PMID:15064403 NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISO UniProtKB:P10749|UniProtKB:P29466 (PMID:15882992) RGD PMID:15882992 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22795130)		 UniProt
RGD		 PMID:22795130 GO_REF:0000024 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689 		JBrowse link
G Spon1 spondin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16227578)		 Ensembl
RGD		 PMID:16227578 GO_REF:0000107 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:105100 (PMID:17344476) RGD PMID:17344476 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A IMP RGD PMID:9756630 RGD:13463485 NCBI chr13:46,731,117...46,742,604
Ensembl chr13:46,730,660...46,742,655 		JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 IMP RGD PMID:9756630 RGD:13463485 NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379
Ensembl chr 3:7,409,688...7,436,379
Ensembl chr 6:7,409,688...7,436,379 		JBrowse link
G Tnp1 transition protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28366643)		 UniProt
RGD		 PMID:28366643 GO_REF:0000024 NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274 		JBrowse link
G Tnp2 transition protein 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:28366643)		 UniProt
Ensembl
RGD		 PMID:28366643 GO_REF:0000024 GO_REF:0000107 NCBI chr10:4,879,812...4,880,540
Ensembl chr10:4,879,812...4,880,538 		JBrowse link
positive regulation of protein processing in phagocytic vesicle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in IEA
ISO		 GO_REF:0000107
(PMID:23325791)		 Ensembl
RGD		 PMID:23325791 GO_REF:0000107 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Myh9 myosin, heavy chain 9 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23325791)		 Ensembl
RGD		 PMID:23325791 GO_REF:0000107 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
protein autoprocessing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 involved_in ISO (PMID:19656850) RGD PMID:19656850 NCBI chr18:60,954,268...60,999,110
Ensembl chr18:60,954,268...60,999,110 		JBrowse link
G Capn1 calpain 1 IC
IDA		 RGD PMID:17429681 PMID:17182728 RGD:1626249, RGD:2303057 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177 		JBrowse link
G Capn2 calpain 2 IDA RGD PMID:17182728 RGD:2303057 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969 		JBrowse link
G Casp1 caspase 1 involved_in ISO
ISS
IEA		 (PMID:11821383), (PMID:32109412)
(PMID:21147462)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:11821383 PMID:21147462 PMID:32109412 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 IDA RGD PMID:18332441 RGD:2311459 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp4 caspase 4 involved_in ISO (PMID:32109412), (PMID:34671164)
(PMID:30392956), (PMID:32109412)		 RGD PMID:30392956 PMID:32109412 PMID:34671164 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp6 caspase 6 involved_in ISO
IEA
ISS		 (PMID:19133298)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19133298 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Ctse cathepsin E IMP RGD PMID:16367762 RGD:2325171 NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502 		JBrowse link
G Ctsl cathepsin L involved_in ISS
ISO		 GO_REF:0000024
(PMID:9468501)		 UniProt
RGD		 PMID:9468501 GO_REF:0000024 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Dhh desert hedgehog signaling molecule involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G F12 coagulation factor XII involved_in ISO
IEA		 (PMID:18725990)
GO_REF:0000107		 RGD
Ensembl		 PMID:18725990 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Fam111a FAM111 trypsin like peptidase A involved_in ISO (PMID:32165630) RGD PMID:32165630 NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547 		JBrowse link
G Fxn frataxin involved_in ISO
IEA		 (PMID:12785837)
GO_REF:0000107		 RGD
Ensembl		 PMID:12785837 GO_REF:0000107 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Hjv hemojuvelin BMP co-receptor involved_in ISO (PMID:18335997) RGD PMID:18335997 NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Myrf myelin regulatory factor involved_in IBA
ISO		 GO_REF:0000033
(PMID:30249802)		 GO_Central
RGD		 PMID:30249802 GO_REF:0000033 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157 		JBrowse link
G Myrfl myelin regulatory factor-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:52,403,324...52,519,907
Ensembl chr 7:52,403,650...52,519,907 		JBrowse link
G Oma1 OMA1 zinc metallopeptidase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:24550258), (PMID:24719224)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24550258 PMID:24719224 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:118,083,728...118,136,980
Ensembl chr 5:118,083,728...118,136,980 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IDA RGD PMID:16093393 RGD:1601081 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IMP RGD PMID:9556596 RGD:2308914 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 involved_in ISO (PMID:16893422) RGD PMID:16893422 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in IDA
ISO		 (PMID:14622975) RGD PMID:14622975 PMID:14622975 RGD:1582518 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in ISO (PMID:17159900) RGD PMID:17159900 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Pisd phosphatidylserine decarboxylase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:77,941,927...77,991,021
Ensembl chr14:77,941,948...77,991,003 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sprtn SprT-like N-terminal domain involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:27852435), (PMID:27871365), (PMID:27871366), (PMID:32649882)		 Ensembl
UniProt
RGD		 PMID:27852435 PMID:27871365 PMID:27871366 PMID:32649882 GO_REF:0000024 GO_REF:0000107 NCBI chr19:52,857,612...52,864,864
Ensembl chr19:52,857,866...52,864,864 		JBrowse link
G Tmprss2 transmembrane serine protease 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715 		JBrowse link
protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Immp1l inner mitochondrial membrane peptidase subunit 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:92,385,329...92,449,559
Ensembl chr 3:92,385,379...92,452,313 		JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 acts_upstream_of_or_within ISO SGD:S000004638 (PMID:15814844) RGD PMID:15814844 NCBI chr 6:58,070,035...58,970,165
Ensembl chr 6:58,070,283...58,969,840 		JBrowse link
G Mipep mitochondrial intermediate peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:34,926,198...35,051,722
Ensembl chr15:34,926,207...35,051,727 		JBrowse link
G Pmpca peptidase, mitochondrial processing subunit alpha involved_in ISO
IBA
IEA
ISS		 (PMID:22354088), (PMID:25808372)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:22354088 PMID:25808372 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:9,207,731...9,216,846
Ensembl chr 3:9,207,717...9,216,844 		JBrowse link
G Pmpcb peptidase, mitochondrial processing subunit beta involved_in IDA
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
PMID:22354088
(PMID:22354088)		 GO_Central
Ensembl
RGD		 PMID:22354088 PMID:12433926 PMID:22354088 GO_REF:0000033 GO_REF:0000107, RGD:13463464, RGD:14995326 NCBI chr 4:13,297,583...13,310,363
Ensembl chr 4:13,297,559...13,310,367 		JBrowse link
regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) RGD PMID:10924275 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434 		JBrowse link
G Cwh43 cell wall biogenesis 43 C-terminal homolog acts_upstream_of_or_within ISO (PMID:34380733) RGD PMID:34380733 NCBI chr14:34,754,279...34,800,530
Ensembl chr14:34,754,289...34,800,814 		JBrowse link
G Ift52 intraflagellar transport 52 acts_upstream_of_or_within ISO (PMID:15930098) RGD PMID:15930098 NCBI chr 3:151,672,505...151,696,975
Ensembl chr 3:151,672,493...151,696,980 		JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:1859153|MGI:3027342 (PMID:15930098), (PMID:16254602) RGD PMID:15930098 PMID:16254602 NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147 		JBrowse link
G Inpp5b inositol polyphosphate-5-phosphatase B acts_upstream_of_or_within ISO MGI:2159609 (PMID:11784089) RGD PMID:11784089 NCBI chr 5:136,996,766...137,061,315
Ensembl chr 5:136,996,686...137,061,315 		JBrowse link
G Ldlrad3 low density lipoprotein receptor class A domain containing 3 acts_upstream_of_or_within ISO (PMID:21795536) RGD PMID:21795536 NCBI chr 3:88,239,529...88,481,340
Ensembl chr 3:88,239,622...88,481,267 		JBrowse link
G Notch4 notch receptor 4 acts_upstream_of_or_within ISO (PMID:24667410) RGD PMID:24667410 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97760 (PMID:22007132)		 Ensembl
RGD		 PMID:22007132 GO_REF:0000107 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97592 (PMID:22007132)		 Ensembl
RGD		 PMID:22007132 GO_REF:0000107 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Prss37 serine protease 37 involved_in ISO (PMID:27649891) RGD PMID:27649891 NCBI chr 4:69,322,977...69,334,555
Ensembl chr 4:69,322,977...69,334,555 		JBrowse link
G Rfx4 regulatory factor X4 acts_upstream_of_or_within ISO MGI:3799278 (PMID:19887680) RGD PMID:19887680 NCBI chr 7:18,853,065...19,015,378
Ensembl chr 7:18,853,322...19,014,967 		JBrowse link
G Rnf139 ring finger protein 139 involved_in ISO (PMID:19706601) RGD PMID:19706601 NCBI chr 7:90,439,726...90,450,911
Ensembl chr 7:90,436,621...90,488,009 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (PMID:16585392) RGD PMID:16585392 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739 		JBrowse link
signal peptide processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arxes1 adipocyte-related X-chromosome expressed sequence 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:98,950,530...98,952,049
Ensembl chr  X:98,950,528...98,952,045 		JBrowse link
G Arxes2 adipocyte-related X-chromosome expressed sequence 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:98,985,844...98,987,425
Ensembl chr  X:98,985,959...98,986,501
Ensembl chr  X:98,985,959...98,986,501 		JBrowse link
G Cln5 CLN5, intracellular trafficking protein involved_in ISO (PMID:20052765) RGD PMID:20052765 NCBI chr15:79,893,573...79,903,438
Ensembl chr15:79,893,548...79,903,438
Ensembl chr 2:79,893,548...79,903,438 		JBrowse link
G ENSRNOG00000068334 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr 4:102,869,248...102,869,735 JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO
IEA		 (PMID:16912035)
(PMID:26416966)
GO_REF:0000107		 RGD
Ensembl		 PMID:16912035 PMID:26416966 GO_REF:0000107 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
G Hm13 histocompatibility minor 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:141,145,792...141,183,557
Ensembl chr 3:141,145,782...141,184,703 		JBrowse link
G Immp1l inner mitochondrial membrane peptidase subunit 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:92,385,329...92,449,559
Ensembl chr 3:92,385,379...92,452,313 		JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:58,070,035...58,970,165
Ensembl chr 6:58,070,283...58,969,840 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 involved_in ISO (PMID:16912035) RGD PMID:16912035 NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600 		JBrowse link
G Sec11a SEC11 homolog A, signal peptidase complex subunit involved_in ISO
IBA
IEA
ISS		 (PMID:34388369)
GO_REF:0000033
GO_REF:0000104
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:34388369 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:134,881,448...134,909,427
Ensembl chr 1:134,875,265...134,915,069 		JBrowse link
G Sec11c SEC11 homolog C, signal peptidase complex subunit involved_in IEA
IBA
ISS
ISO		 GO_REF:0000104
GO_REF:0000033
GO_REF:0000002
GO_REF:0000024
(PMID:34388369)		 UniProt
GO_Central
InterPro
RGD		 PMID:34388369 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr18:59,320,932...59,337,272
Ensembl chr18:59,320,884...59,337,364 		JBrowse link
G Spcs1 signal peptidase complex subunit 1 involved_in ISO
IBA		 (PMID:34388369)
GO_REF:0000033		 RGD
GO_Central		 PMID:34388369 GO_REF:0000033 NCBI chr16:6,190,208...6,191,776
Ensembl chr16:6,190,262...6,192,000 		JBrowse link
G Spcs2 signal peptidase complex subunit 2 involved_in ISO
IBA		 (PMID:34388369)
GO_REF:0000033		 RGD
GO_Central		 PMID:34388369 GO_REF:0000033 NCBI chr 1:154,163,724...154,183,152
Ensembl chr 1:154,163,724...154,183,186 		JBrowse link
G Spcs3 signal peptidase complex subunit 3 involved_in ISO
IBA		 (PMID:34388369)
GO_REF:0000033		 RGD
GO_Central		 PMID:34388369 GO_REF:0000033 NCBI chr16:37,305,358...37,310,792
Ensembl chr16:37,305,305...37,331,746 		JBrowse link
G Sppl3 signal peptide peptidase like 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:41,515,635...41,600,079
Ensembl chr12:41,515,640...41,600,126 		JBrowse link
signaling receptor ligand precursor processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 involved_in ISO (PMID:14993236), (PMID:31838721) RGD PMID:14993236 PMID:31838721 NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO MGI:1857753|MGI:4354847 (PMID:14993236), (PMID:17169360), (PMID:28751722) RGD PMID:14993236 PMID:17169360 PMID:28751722 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Bace1 beta-secretase 1 involved_in ISO MGI:2389228 (PMID:17099708) RGD PMID:17099708 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bace2 beta-secretase 2 involved_in ISO MGI:109548 (PMID:31838721) RGD PMID:31838721 NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G Casp1 caspase 1 involved_in ISO UniProtKB:P10749|UniProtKB:Q9NPP4 (PMID:15882992) RGD PMID:15882992 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Cstl1 cystatin-like 1 involved_in ISO
IBA		 (PMID:12869695)
GO_REF:0000033		 RGD
GO_Central		 PMID:12869695 GO_REF:0000033 NCBI chr 3:136,199,914...136,204,912
Ensembl chr 3:136,199,914...136,204,912 		JBrowse link
G Mep1a meprin A subunit alpha involved_in ISO (PMID:22923609) RGD PMID:22923609 NCBI chr 9:17,474,634...17,504,147
Ensembl chr 9:17,474,619...17,504,147 		JBrowse link
trypsinogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cuzd1 CUB and zona pellucida-like domains 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:12401800)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:12401800 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:186,089,422...186,130,536
Ensembl chr 1:186,089,423...186,102,546 		JBrowse link
vacuolar protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgmn legumain involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480 		JBrowse link
G Tmem208 transmembrane protein 208 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:33,203,587...33,206,287
Ensembl chr19:33,203,587...33,212,183 		JBrowse link
zymogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1r complement C1r involved_in ISO
IBA		 (PMID:20178990)
GO_REF:0000033		 RGD
GO_Central		 PMID:20178990 GO_REF:0000033 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484 		JBrowse link
G C1rl complement C1r subcomponent like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:157,394,183...157,410,771
Ensembl chr 4:157,394,200...157,410,134 		JBrowse link
G Cd5l Cd5 molecule-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753 		JBrowse link
G Ctsh cathepsin H involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:20435891)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:20435891 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Ctsl cathepsin L involved_in ISO
ISS		 (PMID:9468501)
GO_REF:0000024		 RGD
UniProt		 PMID:9468501 GO_REF:0000024 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G F12 coagulation factor XII involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:18725990), (PMID:6793628), (PMID:89876)		 Ensembl
GO_Central
RGD		 PMID:89876 PMID:6793628 PMID:18725990 GO_REF:0000033 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G F9 coagulation factor IX involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:2592373)		 UniProt
GO_Central
Ensembl
RGD		 PMID:2592373 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:138,352,334...138,396,835
Ensembl chr  X:138,352,298...138,396,835 		JBrowse link
G Fcrl1 Fc receptor-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:172,809,442...172,829,780
Ensembl chr 2:172,790,934...172,829,753 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO
IEA		 (PMID:11799113), (PMID:9130696)
GO_REF:0000107		 RGD
Ensembl		 PMID:9130696 PMID:11799113 GO_REF:0000107 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23682772)		 UniProt
RGD		 PMID:23682772 GO_REF:0000024 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Hgfac HGF activator involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278 		JBrowse link
G Klk1 kallikrein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754 		JBrowse link
G Klk1b3 kallikrein 1-related peptidase B3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,709,105...94,713,308
Ensembl chr 1:94,709,105...94,713,308 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Klk1c12 kallikrein 1-related peptidase C12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,378,103...94,382,140
Ensembl chr 1:94,378,054...94,382,176 		JBrowse link
G Klk1c2 kallikrein 1-related peptidase C2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,492,332...94,496,480
Ensembl chr 1:94,492,332...94,496,481 		JBrowse link
G Klk1c3 kallikrein 1-related peptidase C3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,671,636...94,675,417
Ensembl chr 1:94,671,618...94,675,417 		JBrowse link
G Klk1c6 kallikrein 1-related peptidase C6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,467,626...94,475,842
Ensembl chr 1:94,467,672...94,475,806 		JBrowse link
G Klk1c8 kallikrein 1-related peptidase C8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,547,774...94,552,287
Ensembl chr 1:94,547,774...94,551,636 		JBrowse link
G Klk1c9 kallikrein 1-related peptidase C9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,597,359...94,601,245
Ensembl chr 1:94,597,359...94,601,245 		JBrowse link
G Masp1 MBL associated serine protease 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974 		JBrowse link
G Mmp14 matrix metallopeptidase 14 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:20666777)
MGI:2386246 (PMID:15572153)
GO_REF:0000033		 RGD
GO_Central		 PMID:15572153 PMID:20666777 GO_REF:0000033 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Oma1 OMA1 zinc metallopeptidase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:24550258), (PMID:24719224)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24550258 PMID:24719224 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:118,083,728...118,136,980
Ensembl chr 5:118,083,728...118,136,980 		JBrowse link
G Or12j2 olfactory receptor family 12 subfamily J member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:195,209,804...195,210,721
Ensembl chr 1:195,208,141...195,212,120 		JBrowse link
G Prss12 serine protease 12 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:17223089)		 GO_Central
RGD		 PMID:17223089 GO_REF:0000033 NCBI chr 2:211,624,134...211,684,126
Ensembl chr 2:211,624,134...211,684,126 		JBrowse link
G Prss3 serine protease 3 involved_in ISO (PMID:6698368) RGD PMID:6698368 NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562 		JBrowse link
G Prss3b protease, serine, 3B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:69,871,810...69,875,518
Ensembl chr 4:69,871,797...69,875,549 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:20666777) RGD PMID:20666777 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO (PMID:11799113), (PMID:9130696) RGD PMID:9130696 PMID:11799113 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        macromolecule metabolic process 9812
          protein metabolic process 5297
            protein maturation 643
              protein processing 269
                CAAX-box protein processing 3
                Notch receptor processing, ligand-independent 0
                activation of plasma proteins involved in acute inflammatory response + 3
                dibasic protein processing + 1
                mitochondrial protein processing + 13
                negative regulation of protein processing + 25
                positive regulation of protein processing + 30
                protein autoprocessing 27
                protein processing in phagocytic vesicle + 2
                protein splicing + 3
                regulation of protein processing + 68
                signal peptide processing + 16
                signaling receptor ligand precursor processing + 37
                vacuolar protein processing 2
                zymogen activation + 68
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        biosynthetic process 8474
          macromolecule biosynthetic process 7498
            gene expression 7054
              protein maturation 643
                protein processing 269
                  CAAX-box protein processing 3
                  Notch receptor processing, ligand-independent 0
                  activation of plasma proteins involved in acute inflammatory response + 3
                  dibasic protein processing + 1
                  mitochondrial protein processing + 13
                  negative regulation of protein processing + 25
                  positive regulation of protein processing + 30
                  protein autoprocessing 27
                  protein processing in phagocytic vesicle + 2
                  protein splicing + 3
                  regulation of protein processing + 68
                  signal peptide processing + 16
                  signaling receptor ligand precursor processing + 37
                  vacuolar protein processing 2
                  zymogen activation + 68
paths to the root