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ONTOLOGY REPORT - ANNOTATIONS


Term:vacuolar proton-transporting V-type ATPase complex
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Accession:GO:0016471 term browser browse the term
Definition:A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.
Comment:See also the cellular component terms 'vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221' and 'vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220' and the molecular function term 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'.
Synonyms:exact_synonym: vacuolar hydrogen-translocating V-type ATPase complex



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vacuolar proton-transporting V-type ATPase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 part_of ISO
ISS
IEA
(PMID:29127204), (PMID:30985297)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:29127204 PMID:30985297 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895
JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr12:31,947,220...31,979,875
Ensembl chr12:31,822,733...32,007,069
JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 part_of ISO
IBA
(PMID:10973252)
GO_REF:0000033
MGI:2151814 (PMID:11498539)
RGD
GO_Central
PMID:10973252 PMID:11498539 GO_REF:0000033 NCBI chr 4:66,760,163...66,842,126
Ensembl chr 4:66,760,159...66,842,110
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 part_of ISO
IBA
(PMID:18752060)
GO_REF:0000033
RGD
GO_Central
PMID:18752060 GO_REF:0000033 NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 part_of ISO
IBA
(PMID:18752060)
GO_REF:0000033
RGD
GO_Central
PMID:18752060 GO_REF:0000033 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 part_of ISO
ISS
(PMID:12414817)
GO_REF:0000024
RGD
UniProt
PMID:12414817 GO_REF:0000024 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F part_of ISO (PMID:18752060) RGD PMID:18752060 NCBI chr 4:58,067,666...58,070,628 JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 part_of ISO PR:P63082 (PMID:12133826) RGD PMID:12133826 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463
JBrowse link
G Atp6v1g2 ATPase H+ transporting V1 subunit G2 part_of TAS
ISO
PR:P63082 (PMID:12133826) RGD PMID:12133826 PMID:11904681 RGD:632223 NCBI chr20:3,587,681...3,591,309
Ensembl chr20:3,587,686...3,590,481
JBrowse link
G Ccdc115 coiled-coil domain containing 115 part_of ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946
JBrowse link
G Dnah10 dynein, axonemal, heavy chain 10 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr12:31,823,451...31,946,857
Ensembl chr12:31,822,733...32,007,069
JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742
JBrowse link
G Tctn2 tectonic family member 2 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr12:31,982,440...32,007,242
Ensembl chr12:31,822,733...32,007,069
JBrowse link
G Tmem199 transmembrane protein 199 part_of ISO
ISS
IEA
(PMID:28296633)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:28296633 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,402,493...63,407,065
Ensembl chr10:63,402,494...63,407,108
JBrowse link
lysosomal proton-transporting V-type ATPase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spaar small regulatory polypeptide of amino acid response located_in ISO (PMID:28024296) RGD PMID:28024296 NCBI chr 5:57,985,423...57,987,482 JBrowse link
vacuolar proton-transporting V-type ATPase, V0 domain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 part_of IEA
ISS
GO_REF:0000002
GO_REF:0000024
InterPro
UniProt
GO_REF:0000002 GO_REF:0000024 NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895
JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:31,947,220...31,979,875
Ensembl chr12:31,822,733...32,007,069
JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:66,760,163...66,842,126
Ensembl chr 4:66,760,159...66,842,110
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500
JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434
JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777
JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742
JBrowse link
vacuolar proton-transporting V-type ATPase, V1 domain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6v1a ATPase H+ transporting V1 subunit A part_of ISO (PMID:33065002) RGD PMID:33065002 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 part_of ISO (PMID:33065002) RGD PMID:33065002 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 part_of IDA
ISO
PMID:32165585
(PMID:33065002)
RGD PMID:33065002 PMID:32165585 RGD:39458019 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745
JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 part_of ISS
IEA
IBA
GO_REF:0000024
GO_REF:0000118
GO_REF:0000033
UniProt
TreeGrafter
GO_Central
GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278
JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 part_of IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028
JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 part_of IDA
IEA
ISO
PMID:32165585
GO_REF:0000107
(PMID:33065002)
Ensembl
RGD
PMID:33065002 PMID:32165585 GO_REF:0000107, RGD:39458019 NCBI chr 4:154,022,358...154,044,486
Ensembl chr 4:154,022,358...154,044,584
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:58,067,666...58,070,628 JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 part_of ISO
IBA
(PMID:33065002)
GO_REF:0000033
RGD
GO_Central
PMID:33065002 GO_REF:0000033 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463
JBrowse link
G Atp6v1g1l1 ATPase H+ transporting V1 subunit G1 like 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:28,663,974...28,664,273
Ensembl chr10:28,663,974...28,664,273
JBrowse link
G Atp6v1g2 ATPase H+ transporting V1 subunit G2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,587,681...3,591,309
Ensembl chr20:3,587,686...3,590,481
JBrowse link
G Atp6v1g3 ATPase H+ transporting V1 subunit G3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:49,800,256...49,825,247
Ensembl chr13:49,794,222...49,825,247
JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      membrane protein complex 1451
        proton-transporting two-sector ATPase complex 73
          proton-transporting V-type ATPase complex 34
            vacuolar proton-transporting V-type ATPase complex 28
              lysosomal proton-transporting V-type ATPase complex + 1
              vacuolar proton-transporting V-type ATPase, V0 domain + 8
              vacuolar proton-transporting V-type ATPase, V1 domain + 12
Path 2
Term Annotations click to browse term
  cellular_component 21392
    cellular anatomical entity 21234
      organelle 14344
        intracellular organelle 13898
          intracellular membrane-bounded organelle 12331
            vacuole 671
              vacuolar membrane 362
                vacuolar proton-transporting V-type ATPase complex 28
                  lysosomal proton-transporting V-type ATPase complex + 1
                  vacuolar proton-transporting V-type ATPase, V0 domain + 8
                  vacuolar proton-transporting V-type ATPase, V1 domain + 12
paths to the root