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ONTOLOGY REPORT - ANNOTATIONS


Term:eukaryotic translation initiation factor 4F complex
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Accession:GO:0016281 term browser browse the term
Definition:The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.
Synonyms:exact_synonym: eIF-4F
 broad_synonym: eukaryotic translation initiation factor 4 complex



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eukaryotic translation initiation factor 4F complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4e eukaryotic translation initiation factor 4E part_of IDA
IBA
ISO
PMID:21873635
(PMID:22578813)
RGD PMID:22578813 PMID:18952566 PMID:21873635 RGD:2307417, RGD:13792537 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:87,886,078...87,901,058
Ensembl chr 9:87,878,085...87,914,482
JBrowse link
G Eif4e3 eukaryotic translation initiation factor 4E family member 3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:132,258,502...132,301,808
Ensembl chr 4:132,258,502...132,301,808
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 part_of IDA
IBA
ISO
PMID:21873635
(PMID:25255371)
RGD PMID:25255371 PMID:18952566 PMID:21873635 RGD:2307417, RGD:13792537 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 part_of ISO
IBA
(PMID:11943866)
PMID:21873635
RGD PMID:11943866 PMID:21873635 RGD:13792537 NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:150,197,410...150,418,363
Ensembl chr 5:150,195,226...150,418,363
JBrowse link
G Otud6b OTU deubiquitinase 6B colocalizes_with
part_of
ISO
IEA
(PMID:27864334)
GO_REF:0000107
RGD
Ensembl
PMID:27864334 GO_REF:0000107 NCBI chr 5:28,181,992...28,214,486
Ensembl chr 5:28,023,594...28,214,334
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19896
    protein-containing complex 5946
      eukaryotic translation initiation factor 4F complex 7
Path 2
Term Annotations click to browse term
  cellular_component 19896
    cellular anatomical entity 19599
      intracellular anatomical structure 14287
        cytoplasm 11289
          eukaryotic translation initiation factor 4F complex 7
paths to the root