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ONTOLOGY REPORT - ANNOTATIONS


Term:eukaryotic translation initiation factor 4F complex
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Accession:GO:0016281 term browser browse the term
Definition:The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.
Synonyms:exact_synonym: eIF-4F
 broad_synonym: eukaryotic translation initiation factor 4 complex


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eukaryotic translation initiation factor 4F complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4e eukaryotic translation initiation factor 4E IDA
IBA
ISO
PMID:21873635
(PMID:22578813)
RGD PMID:22578813, PMID:18952566, PMID:21873635 RGD:2307417, RGD:13792537 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:94,310,476...94,325,445
Ensembl chr 9:94,307,852...94,336,831
JBrowse link
G Eif4e3 eukaryotic translation initiation factor 4E family member 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:132,068,581...132,111,092
Ensembl chr 4:132,068,598...132,111,079
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 IDA
IBA
ISO
PMID:21873635
(PMID:25255371)
RGD PMID:25255371, PMID:18952566, PMID:21873635 RGD:2307417, RGD:13792537 NCBI chr11:83,907,659...83,927,683
Ensembl chr11:83,908,109...83,926,524
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 ISO
IBA
(PMID:11943866)
PMID:21873635
RGD PMID:11943866, PMID:21873635 RGD:13792537 NCBI chr 1:175,883,362...175,895,510
Ensembl chr 1:175,883,363...175,895,510
JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:156,343,663...156,564,037
Ensembl chr 5:156,396,695...156,564,037
JBrowse link
G LOC100912571 eukaryotic translation initiation factor 4 gamma 1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:82,886,428...82,913,153
Ensembl chr11:82,886,878...82,893,845
JBrowse link
G Otud6b OTU deubiquitinase 6B colocalizes_with ISO (PMID:27864334) RGD PMID:27864334 NCBI chr 5:28,333,019...28,350,093
Ensembl chr 5:28,333,019...28,349,927
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      eukaryotic translation initiation factor 4F complex 8
Path 2
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      intracellular anatomical structure 14706
        cytoplasm 11456
          eukaryotic translation initiation factor 4F complex 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.