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ONTOLOGY REPORT - ANNOTATIONS


Term:prefoldin complex
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Accession:GO:0016272 term browser browse the term
Definition:A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
Synonyms:narrow_synonym: GIM complex
 xref: Wikipedia:Prefoldin


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prefoldin complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pfdn1 prefoldin subunit 1 part_of ISO (PMID:23614719), (PMID:30955883) RGD PMID:23614719 PMID:30955883 NCBI chr18:29,233,987...29,290,447
Ensembl chr18:29,233,987...29,290,447
JBrowse link
G Pfdn2 prefoldin subunit 2 part_of ISO (PMID:23614719), (PMID:30955883) RGD PMID:23614719 PMID:30955883 NCBI chr13:89,725,113...89,743,849
Ensembl chr13:89,725,869...89,743,848
JBrowse link
G Pfdn4 prefoldin subunit 4 part_of IBA
ISO
PMID:21873635
(PMID:23614719), (PMID:30955883)
RGD PMID:23614719 PMID:30955883, PMID:21873635 RGD:13792537 NCBI chr 3:168,124,634...168,132,739
Ensembl chr 3:168,124,673...168,132,786
JBrowse link
G Pfdn5 prefoldin subunit 5 part_of ISO
IBA
(PMID:23614719), (PMID:30955883)
PMID:21873635
RGD PMID:23614719 PMID:30955883, PMID:21873635 RGD:13792537 NCBI chr 7:143,924,662...143,929,400
Ensembl chr 7:143,924,662...143,929,397
JBrowse link
G Pfdn6 prefoldin subunit 6 part_of ISO
IBA
(PMID:23614719), (PMID:30955883), (PMID:9630229)
PMID:21873635
RGD PMID:9630229 PMID:23614719 PMID:30955883, PMID:21873635 RGD:13792537 NCBI chr20:5,455,974...5,457,448
Ensembl chr20:5,455,974...5,457,444
JBrowse link
G Vbp1 VHL binding protein 1 part_of IBA
ISO
PMID:21873635
(PMID:23614719), (PMID:30955883)
RGD PMID:23614719 PMID:30955883, PMID:21873635 RGD:13792537 NCBI chr 1:148,425,046...148,443,505
Ensembl chr 1:148,424,977...148,443,358
JBrowse link

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  cellular_component 20142
    protein-containing complex 6031
      prefoldin complex 6
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