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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of macroautophagy
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Accession:GO:0016241 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of macroautophagy.
Synonyms:exact_synonym: regulation of starvation-induced autophagy



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regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG14 autophagy related 14 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:184,701,020...184,743,752
Ensembl chr 1:184,686,142...184,743,753
JBrowse link
G ATP13A2 ATPase cation transporting 13A2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:75,618,317...75,638,591
Ensembl chr 6:75,618,416...75,638,591
JBrowse link
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:20,288,409...20,344,142
Ensembl chr12:20,288,409...20,344,128
JBrowse link
G BECN1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
G HDAC6 histone deacetylase 6 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:42,917,911...42,941,894
Ensembl chr  X:42,917,960...42,941,890
JBrowse link
G MTMR8 myotubularin related protein 8 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:50,931,199...51,077,796
Ensembl chr  X:50,935,136...51,077,766
JBrowse link
G PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:125,890,598...126,038,753
Ensembl chr 6:125,890,708...126,043,161
JBrowse link
G PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:1,730,988...1,815,555
Ensembl chr13:1,731,017...1,815,556
JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:155,683,392...155,754,283
Ensembl chr 6:155,681,781...155,754,272
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,511...6,730,881
JBrowse link
G UBQLN1 ubiquilin 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr10:31,275,916...31,317,521
Ensembl chr10:31,275,868...31,412,935
JBrowse link
G UBQLN2 ubiquilin 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr  X:48,948,062...48,951,392
Ensembl chr  X:48,948,389...48,950,263
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:23,423,693...23,448,130
Ensembl chr14:23,423,696...23,448,138
JBrowse link
negative regulation of autophagosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5888970|PMID:27994061) Ensembl
Ensembl
MGI
PMID:27994061 GO_REF:0000107 MGI:5888970 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
G CHMP4A charged multivesicular body protein 4A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:75,089,092...75,093,796
Ensembl chr 7:75,088,271...75,097,761
JBrowse link
G CHMP4B charged multivesicular body protein 4B involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:37,285,422...37,334,103
Ensembl chr17:37,285,441...37,334,101
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5543871|PMID:23918802) Ensembl
Ensembl
MGI
PMID:23918802 GO_REF:0000107 MGI:5543871 NCBI chr 7:23,977,683...23,992,673
Ensembl chr 7:23,977,683...23,993,478
JBrowse link
G FEZ1 fasciculation and elongation protein zeta 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:52,621,175...52,672,660
Ensembl chr 9:52,621,178...52,672,660
JBrowse link
G FEZ2 fasciculation and elongation protein zeta 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:103,566,214...103,612,855
Ensembl chr 3:103,566,221...103,615,775
JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,240...71,944,938
JBrowse link
G MTM1 myotubularin 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5510937|PMID:23695157)
GO_Central
GO_Central
MGI
PMID:21873635 PMID:23695157 MGI:5510937 NCBI chr  X:122,286,904...122,379,302
Ensembl chr  X:122,286,916...122,379,299
JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:18,402,781...18,404,411
Ensembl chr 3:18,402,935...18,511,087
JBrowse link
G PHF23 PHD finger protein 23 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr12:52,590,801...52,595,208
Ensembl chr12:52,590,801...52,598,175
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:78,863,195...78,884,663
Ensembl chr 6:78,863,190...78,884,644
JBrowse link
G SCFD1 sec1 family domain containing 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:68,694,579...68,851,055
Ensembl chr 7:68,691,239...68,851,008
JBrowse link
G SEC22B SEC22 homolog B, vesicle trafficking protein involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:100,880,843...100,900,942
Ensembl chr 4:100,880,914...100,906,062
JBrowse link
G SMCR8 SMCR8-C9orf72 complex subunit involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:60,435,276...60,443,525
Ensembl chr12:60,435,273...60,443,520
JBrowse link
G TMEM39A transmembrane protein 39A involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr13:140,797,098...140,830,732
Ensembl chr13:140,797,205...140,831,277
JBrowse link
negative regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:31,938,133...32,158,343
Ensembl chr 3:31,938,135...32,158,558
JBrowse link
G PHF23 PHD finger protein 23 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr12:52,590,801...52,595,208
Ensembl chr12:52,590,801...52,598,175
JBrowse link
G RUBCN rubicon autophagy regulator involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr13:134,299,971...134,363,620
Ensembl chr13:134,254,969...134,363,265
JBrowse link
G TMEM39A transmembrane protein 39A involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr13:140,797,098...140,830,732
Ensembl chr13:140,797,205...140,831,277
JBrowse link
G UBQLN4 ubiquilin 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:93,976,386...93,994,830
Ensembl chr 4:93,976,431...93,994,830
JBrowse link
negative regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMOX1 heme oxygenase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5430482|PMID:20705711) Ensembl
MGI
PMID:20705711 GO_REF:0000107 MGI:5430482
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,240...71,944,938
JBrowse link
G LZTS1 leucine zipper tumor suppressor 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:4,344,496...4,404,208
Ensembl chr14:4,344,496...4,404,208
JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25327288)
(MGI:3690270|PMID:16714284), (MGI:5563734|PMID:23274896)
Ensembl
Ensembl
MGI
PMID:16714284 PMID:23274896 PMID:25327288 GO_REF:0000107 MGI:3690270 MGI:5563734 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3723543|PMID:17468177) Ensembl
Ensembl
MGI
PMID:17468177 GO_REF:0000107 MGI:3723543 NCBI chr 6:108,403,126...108,450,486
Ensembl chr 6:108,402,877...108,450,990
JBrowse link
G NRBP2 nuclear receptor binding protein 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:800,722...808,031
Ensembl chr 4:800,059...808,024
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:78,863,195...78,884,663
Ensembl chr 6:78,863,190...78,884,644
JBrowse link
G POLDIP2 DNA polymerase delta interacting protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5588624|PMID:24797518) Ensembl
Ensembl
MGI
PMID:24797518 GO_REF:0000107 MGI:5588624 NCBI chr12:44,626,447...44,636,302
Ensembl chr12:44,625,603...44,636,289
JBrowse link
G QSOX1 quiescin sulfhydryl oxidase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:121,779,072...121,822,829
Ensembl chr 9:121,779,796...121,837,437
JBrowse link
G SMCR8 SMCR8-C9orf72 complex subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:60,435,276...60,443,525
Ensembl chr12:60,435,273...60,443,520
JBrowse link
G SMG1 SMG1 nonsense mediated mRNA decay associated PI3K related kinase involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 3:26,653,819...26,758,268
Ensembl chr 3:26,653,792...26,754,882
JBrowse link
G TSC1 TSC complex subunit 1 involved_in ISO PMID:23435171 ParkinsonsUK-UCL PMID:23435171 RGD:10448950 NCBI chr 1:272,636,530...272,685,948
Ensembl chr 1:272,636,532...272,685,952
JBrowse link
G TSC2 TSC complex subunit 2 ISO RGD PMID:24599401 RGD:11568679 NCBI chr 3:39,898,924...39,935,579
Ensembl chr 3:39,898,922...39,937,371
JBrowse link
G USP36 ubiquitin specific peptidase 36 involved_in ISO (PMID:22622177) UniProt PMID:22622177 NCBI chr12:3,309,176...3,348,531 JBrowse link
negative regulation of macroautophagy by TORC1 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:31,938,133...32,158,343
Ensembl chr 3:31,938,135...32,158,558
JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr 3:31,938,133...32,158,343
Ensembl chr 3:31,938,135...32,158,558
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:78,863,195...78,884,663
Ensembl chr 6:78,863,190...78,884,644
JBrowse link
G RNF41 ring finger protein 41 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5603233|PMID:24949970) Ensembl
Ensembl
MGI
PMID:24949970 GO_REF:0000107 MGI:5603233 NCBI chr 5:21,595,703...21,624,589
Ensembl chr 5:21,596,306...21,624,569
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5319065|PMID:22044588) Ensembl
Ensembl
MGI
PMID:22044588 GO_REF:0000107 MGI:5319065 NCBI chr 5:66,044,679...66,067,571
Ensembl chr 5:66,044,686...66,067,377
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5319065|PMID:22044588) Ensembl
Ensembl
MGI
PMID:22044588 GO_REF:0000107 MGI:5319065 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
G USP30 ubiquitin specific peptidase 30 ISO RGD PMID:24896179 RGD:13208875 NCBI chr14:41,765,220...41,818,937
Ensembl chr14:41,765,230...41,818,890
JBrowse link
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VPS13C vacuolar protein sorting 13 homolog C involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:109,931,269...110,105,519
Ensembl chr 1:109,931,264...110,104,241
JBrowse link
positive regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG3 BAG cochaperone 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:129,510,240...129,533,998
Ensembl chr14:129,510,293...129,533,996
JBrowse link
G HSPB8 heat shock protein family B (small) member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:33,626,125...33,639,824
Ensembl chr14:33,626,128...33,640,792
JBrowse link
G HTT huntingtin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:1,809,768...1,934,002
Ensembl chr 8:1,809,785...1,934,024
JBrowse link
positive regulation of autophagosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG2A autophagy related 2A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:7,261,819...7,282,614
Ensembl chr 2:7,261,756...7,282,608
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
G ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:110,881,770...110,954,092
Ensembl chr 4:110,881,773...110,954,065
JBrowse link
G LRSAM1 leucine rich repeat and sterile alpha motif containing 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:267,964,875...268,008,833
Ensembl chr 1:267,964,928...268,008,825
JBrowse link
G MOAP1 modulator of apoptosis 1 involved_in ISO (PMID:33783314)
(MGI:6810697|PMID:33783314)
UniProt PMID:33783314 MGI:6810697 NCBI chr 7:114,571,624...114,574,052 JBrowse link
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:52,224,367...52,408,928
Ensembl chr10:52,223,425...52,408,922
JBrowse link
G PIP4K2B phosphatidylinositol-5-phosphate 4-kinase type 2 beta involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:23,317,113...23,345,661
Ensembl chr12:23,317,185...23,346,424
JBrowse link
G PIP4K2C phosphatidylinositol-5-phosphate 4-kinase type 2 gamma involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:22,854,142...22,867,032
Ensembl chr 5:22,854,137...22,867,037
JBrowse link
G RAB3GAP1 RAB3 GTPase activating protein catalytic subunit 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:16,756,368...16,893,148
Ensembl chr15:16,753,877...16,816,754
JBrowse link
G RAB3GAP2 RAB3 GTPase activating non-catalytic protein subunit 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:9,734,766...9,828,330
Ensembl chr10:9,734,767...9,828,345
JBrowse link
G RALB RAS like proto-oncogene B involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:31,064,341...31,118,437
Ensembl chr15:31,064,355...31,122,621
JBrowse link
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:129,361,596...129,395,790
Ensembl chr 4:129,357,548...129,395,583
JBrowse link
G SNX18 sorting nexin 18 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:33,776,964...33,801,391
Ensembl chr16:33,776,672...33,863,054
JBrowse link
G SNX30 sorting nexin family member 30 involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 1:253,428,461...253,555,463
Ensembl chr 1:253,428,508...253,550,375
JBrowse link
G SNX4 sorting nexin 4 involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr13:134,824,028...134,903,765
Ensembl chr13:134,824,043...134,905,359
JBrowse link
G SNX7 sorting nexin 7 involved_in IEA
IBA
(PMID:21873635) Ensembl
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 4:119,040,986...119,258,507
Ensembl chr 4:118,986,423...119,255,900
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 ISO RGD PMID:23448468 RGD:13208863 NCBI chr14:23,423,693...23,448,130
Ensembl chr14:23,423,696...23,448,138
JBrowse link
G WDR45 WD repeat domain 45 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:43,150,691...43,155,981
Ensembl chr  X:43,147,476...43,156,195
JBrowse link
G WIPI1 WD repeat domain, phosphoinositide interacting 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:11,715,332...11,752,009
Ensembl chr12:11,715,318...11,752,021
JBrowse link
positive regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 involved_in IEA
ISS
Ensembl
GO_Central
Ensembl
GO_Central
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:150,032,649...150,035,591
Ensembl chr 2:150,032,782...150,035,591
JBrowse link
G CALCOCO2 calcium binding and coiled-coil domain 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr12:25,050,008...25,080,230
Ensembl chr12:24,867,138...25,088,925
JBrowse link
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr 3:31,938,133...32,158,343
Ensembl chr 3:31,938,135...32,158,558
JBrowse link
G FYCO1 FYVE and coiled-coil domain autophagy adaptor 1 involved_in IEA
IBA
(PMID:21873635) InterPro
InterPro
GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000002 GO_REF:0000107 NCBI chr13:29,068,107...29,146,792
Ensembl chr13:29,066,986...29,146,755
JBrowse link
G SMCR8 SMCR8-C9orf72 complex subunit involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:60,435,276...60,443,525
Ensembl chr12:60,435,273...60,443,520
JBrowse link
positive regulation of lipophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 involved_in ISS
IEA
GO_Central
Ensembl
GO_Central
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:150,032,649...150,035,591
Ensembl chr 2:150,032,782...150,035,591
JBrowse link
G HTT huntingtin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:1,809,768...1,934,002
Ensembl chr 8:1,809,785...1,934,024
JBrowse link
G SESN2 sestrin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5444071|PMID:22958918) Ensembl
Ensembl
MGI
PMID:22958918 GO_REF:0000107 MGI:5444071 NCBI chr 6:85,321,982...85,348,044
Ensembl chr 6:85,324,228...85,348,044
JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25332431) MGI
Ensembl
Ensembl
PMID:25332431 GO_REF:0000107 NCBI chr14:3,081,964...3,138,113
Ensembl chr14:3,081,969...3,138,103
JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25332431) MGI
Ensembl
Ensembl
PMID:25332431 GO_REF:0000107 NCBI chr 7:100,545,360...100,638,973
Ensembl chr 7:100,544,478...100,638,907
JBrowse link
positive regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BNIP3 BCL2 interacting protein 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:19273585) MGI
Ensembl
Ensembl
PMID:19273585 GO_REF:0000107 NCBI chr14:140,362,123...140,371,951
Ensembl chr14:140,362,127...140,371,881
JBrowse link
G BNIP3L BCL2 interacting protein 3 like acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:19273585) MGI
Ensembl
Ensembl
PMID:19273585 GO_REF:0000107 NCBI chr14:10,318,688...10,345,689
Ensembl chr14:10,318,714...10,345,683
JBrowse link
G C9orf72 C9orf72-SMCR8 complex subunit involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:38,389,366...38,415,903
Ensembl chr10:38,389,331...38,415,903
JBrowse link
G DCN decorin acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23798385) MGI
Ensembl
Ensembl
PMID:23798385 GO_REF:0000107 NCBI chr 5:91,678,601...91,713,925
Ensembl chr 5:91,678,608...91,714,235
JBrowse link
G FBXO30 F-box protein 30 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,806,363...19,893,350
Ensembl chr 1:19,755,720...20,024,398
JBrowse link
G FBXO30 F-box protein 30 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,756,232...19,777,621
Ensembl chr 1:19,755,720...20,024,398
JBrowse link
G GNAI3 G protein subunit alpha i3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:110,527,363...110,579,331
Ensembl chr 4:110,525,547...110,579,020
JBrowse link
G GPSM1 G protein signaling modulator 1 involved_in ISO (PMID:12642577) UniProt PMID:12642577
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3847365|PMID:19273585) Ensembl
Ensembl
MGI
PMID:19273585 GO_REF:0000107 MGI:3847365 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G HMOX1 heme oxygenase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5430482|PMID:20705711) Ensembl
MGI
PMID:20705711 GO_REF:0000107 MGI:5430482
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (MGI:5819337|PMID:23778976) ParkinsonsUK-UCL PMID:23778976 MGI:5819337 NCBI chr  X:125,035,575...125,056,445
Ensembl chr  X:125,036,508...125,056,453
JBrowse link
G IL4 interleukin 4 involved_in IBA
ISS
(PMID:21873635) GO_Central
UniProt
GO_Central
UniProt
PMID:21873635 GO_REF:0000024 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G KDR kinase insert domain receptor acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23798385) MGI
Ensembl
Ensembl
PMID:23798385 GO_REF:0000107 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,116...41,856,339
JBrowse link
G LARP1 La ribonucleoprotein 1, translational regulator involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:68,390,879...68,451,605
Ensembl chr16:68,390,875...68,484,918
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (MGI:5819337|PMID:23778976) ParkinsonsUK-UCL PMID:23778976 MGI:5819337 NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057
JBrowse link
G PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:44,513,114...44,534,312
Ensembl chr 9:44,513,456...44,536,432
JBrowse link
G PIM2 Pim-2 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:4361989|PMID:17476689) MGI PMID:17476689 MGI:4361989 NCBI chr  X:42,993,547...42,998,575
Ensembl chr  X:42,993,551...42,998,576
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:78,863,195...78,884,663
Ensembl chr 6:78,863,190...78,884,644
JBrowse link
G RAB12 RAB12, member RAS oncogene family involved_in ISO (MGI:5574288|PMID:23357852) UniProt PMID:23357852 MGI:5574288 NCBI chr 6:99,216,225...99,244,627
Ensembl chr 6:99,216,228...99,244,868
JBrowse link
G RUFY4 RUN and FYVE domain containing 4 involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr15:120,193,657...120,213,625
Ensembl chr15:120,192,235...120,213,462
JBrowse link
G SCOC short coiled-coil protein involved_in ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chr 8:86,680,782...86,690,691
Ensembl chr 8:86,679,840...86,719,164
JBrowse link
G SESN1 sestrin 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 1:75,056,731...75,170,374
Ensembl chr 1:75,033,098...75,169,987
JBrowse link
G SESN2 sestrin 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 6:85,321,982...85,348,044
Ensembl chr 6:85,324,228...85,348,044
JBrowse link
G SESN3 sestrin 3 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 9:27,207,239...27,279,205
Ensembl chr 9:27,207,236...27,298,628
JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,157...71,123,299
JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in ISS
IBA
IEA
(PMID:21873635) UniProt
GO_Central
Ensembl
UniProt
GO_Central
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:141,359,402...141,367,222
Ensembl chr 2:141,358,993...141,367,198
JBrowse link
G SUPT5H SPT5 homolog, DSIF elongation factor subunit involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:48,095,001...48,125,120
Ensembl chr 6:48,089,773...48,172,972
JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:28,880,210...28,929,964
Ensembl chr 5:28,828,568...28,929,964
JBrowse link
G TRIM13 tripartite motif containing 13 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr11:17,785,031...17,850,005
Ensembl chr11:17,792,467...17,849,732
JBrowse link
G TSC1 TSC complex subunit 1 ISO RGD PMID:23435171 RGD:10448950 NCBI chr 1:272,636,530...272,685,948
Ensembl chr 1:272,636,532...272,685,952
JBrowse link
G TSC2 TSC complex subunit 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4457987|PMID:20453062) Ensembl
Ensembl
MGI
PMID:20453062 GO_REF:0000107 MGI:4457987 NCBI chr 3:39,898,924...39,935,579
Ensembl chr 3:39,898,922...39,937,371
JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:39,932,562...40,024,114
Ensembl chr10:39,932,570...40,024,115
JBrowse link
G WDR24 WD repeat domain 24 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:41,085,415...41,090,628
Ensembl chr 3:41,085,442...41,090,631
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:15,935,354...16,119,082
Ensembl chr 2:15,917,698...16,119,082
JBrowse link
G CERS1 ceramide synthase 1 involved_in ISO (PMID:22922758) UniProt PMID:22922758 NCBI chr 2:58,951,463...58,972,692 JBrowse link
G GDF1 growth differentiation factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:58,972,918...58,976,294
Ensembl chr 2:58,951,726...58,974,672
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:28608965 RGD:13432560 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,511...6,730,881
JBrowse link
G SLC25A4 solute carrier family 25 member 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:46,193,498...46,197,989
Ensembl chr15:46,193,699...46,200,994
JBrowse link
G SLC25A5 solute carrier family 25 member 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:97,919,295...97,922,245
Ensembl chr  X:97,919,290...97,922,245
JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chr 2:136,302,188...136,334,461
Ensembl chr 2:136,302,192...136,413,595
JBrowse link
G VPS13D vacuolar protein sorting 13 homolog D involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:72,256,865...72,514,256
Ensembl chr 6:72,256,877...72,510,907
JBrowse link
positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VDAC1 voltage dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chr 2:136,302,188...136,334,461
Ensembl chr 2:136,302,192...136,413,595
JBrowse link
positive regulation of xenophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRSAM1 leucine rich repeat and sterile alpha motif containing 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:267,964,875...268,008,833
Ensembl chr 1:267,964,928...268,008,825
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5299952|PMID:22033934) Ensembl
Ensembl
MGI
PMID:22033934 GO_REF:0000107 MGI:5299952 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr18:42,464,667...42,509,135
Ensembl chr18:42,432,050...42,512,266
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5299952|PMID:22033934) Ensembl
Ensembl
MGI
PMID:22033934 GO_REF:0000107 MGI:5299952 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534
JBrowse link
G OPTN optineurin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:48,532,029...48,582,952
Ensembl chr10:48,530,844...48,582,910
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5299952|PMID:22033934) Ensembl
Ensembl
MGI
PMID:22033934 GO_REF:0000107 MGI:5299952 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,092...47,074,725
JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:28,880,210...28,929,964
Ensembl chr 5:28,828,568...28,929,964
JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,991...75,446,850
JBrowse link
regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG12 autophagy related 12 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:119,948,443...119,965,702
Ensembl chr 2:119,941,997...119,965,510
JBrowse link
G ATG5 autophagy related 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:72,343,950...72,520,402
Ensembl chr 1:72,270,799...72,520,453
JBrowse link
G CLEC16A C-type lectin domain containing 16A involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 3:31,938,133...32,158,343
Ensembl chr 3:31,938,135...32,158,558
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:18,433,564...18,450,296
Ensembl chr 3:18,433,559...18,450,293
JBrowse link
G TBC1D25 TBC1 domain family member 25 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr  X:42,682,267...42,696,579
Ensembl chr  X:42,682,268...42,696,579
JBrowse link
G TECPR1 tectonin beta-propeller repeat containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:5,414,071...5,442,953
Ensembl chr 3:5,414,073...5,442,943
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17278
    cellular process 16306
      process utilizing autophagic mechanism 472
        autophagy 472
          macroautophagy 258
            regulation of macroautophagy 118
              negative regulation of macroautophagy + 33
              positive regulation of macroautophagy + 76
              regulation of aggrephagy + 3
              regulation of autophagosome maturation + 14
              regulation of lipophagy + 5
              regulation of mitophagy + 15
              regulation of reticulophagy + 0
              regulation of xenophagy + 8
Path 2
Term Annotations click to browse term
  biological_process 17278
    biological regulation 12771
      regulation of biological process 12136
        regulation of cellular process 11457
          regulation of cellular metabolic process 5451
            regulation of cellular catabolic process 755
              regulation of autophagy 295
                regulation of macroautophagy 118
                  negative regulation of macroautophagy + 33
                  positive regulation of macroautophagy + 76
                  regulation of aggrephagy + 3
                  regulation of autophagosome maturation + 14
                  regulation of lipophagy + 5
                  regulation of mitophagy + 15
                  regulation of reticulophagy + 0
                  regulation of xenophagy + 8
paths to the root