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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of macroautophagy
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Accession:GO:0016241 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of macroautophagy.
Synonyms:exact_synonym: regulation of starvation-induced autophagy


show annotations for term's descendants           Sort by:
regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg14 autophagy related 14 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:47,778,350...47,805,891
Ensembl chr14:47,778,350...47,808,106 		JBrowse link
G Atp13a2 ATPase type 13A2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:140,711,812...140,734,641
Ensembl chr 4:140,714,184...140,734,641 		JBrowse link
G Atp6v0a1 ATPase, H+ transporting, lysosomal V0 subunit A1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:100,899,262...100,954,545
Ensembl chr11:100,900,278...100,954,545 		JBrowse link
G Becn1 beclin 1, autophagy related involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:7,796,355...7,814,284
Ensembl chr  X:7,796,359...7,814,128 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase catalytic subunit type 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:30,390,441...30,481,179
Ensembl chr18:30,405,800...30,481,179 		JBrowse link
G Pik3r4 phosphoinositide-3-kinase regulatory subunit 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:105,520,156...105,564,854
Ensembl chr 9:105,520,177...105,564,856 		JBrowse link
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit involved_in IDA (MGI:5619439|PMID:23332761) UniProt PMID:23332761 MGI:5619439 NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:58,323,970...58,363,467
Ensembl chr13:58,323,970...58,363,467 		JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr  X:152,281,228...152,284,558
Ensembl chr  X:152,281,223...152,284,566 		JBrowse link
G Ulk1 unc-51 like kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963 		JBrowse link
negative regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:7,796,355...7,814,284
Ensembl chr  X:7,796,359...7,814,128 		JBrowse link
G Lypla1 lysophospholipase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:4,878,046...4,916,958
Ensembl chr 1:4,878,011...4,918,633 		JBrowse link
negative regulation of autophagosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1, autophagy related acts_upstream_of_or_within IMP (PMID:27994061) MGI PMID:27994061 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Ehmt2 euchromatic histone lysine N-methyltransferase 2 acts_upstream_of_or_within IMP (PMID:23918802) MGI PMID:23918802 NCBI chr17:35,117,427...35,133,049
Ensembl chr17:35,117,445...35,133,028 		JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:36,732,694...36,790,220
Ensembl chr 9:36,733,160...36,790,220 		JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:78,676,641...78,725,581
Ensembl chr17:78,676,641...78,725,581 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323 		JBrowse link
G Mtm1 X-linked myotubular myopathy gene 1 involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:23695157) GO_Central
MGI		 PMID:23695157 GO_REF:0000033 NCBI chr  X:70,254,373...70,359,019
Ensembl chr  X:70,254,373...70,359,297 		JBrowse link
G Nupr1 nuclear protein transcription regulator 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033 		JBrowse link
G Phf23 PHD finger protein 23 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:69,886,592...69,890,837
Ensembl chr11:69,886,603...69,890,835 		JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Scfd1 Sec1 family domain containing 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:51,424,296...51,496,887
Ensembl chr12:51,424,293...51,496,884 		JBrowse link
G Sec22b SEC22 homolog B, vesicle trafficking protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:97,808,543...97,829,634
Ensembl chr 3:97,808,506...97,830,592 		JBrowse link
G Smcr8 Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:60,668,351...60,679,113
Ensembl chr11:60,668,350...60,679,113 		JBrowse link
G Tmem39a transmembrane protein 39a involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr16:38,379,060...38,412,524
Ensembl chr16:38,379,060...38,412,524 		JBrowse link
negative regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain family 16, member A involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742 		JBrowse link
G Phf23 PHD finger protein 23 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:69,886,592...69,890,837
Ensembl chr11:69,886,603...69,890,835 		JBrowse link
G Rubcn RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr16:32,642,072...32,698,121
Ensembl chr16:32,642,073...32,698,136 		JBrowse link
G Tmem39a transmembrane protein 39a involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr16:38,379,060...38,412,524
Ensembl chr16:38,379,060...38,412,524 		JBrowse link
G Ubqln4 ubiquilin 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:88,460,984...88,477,032
Ensembl chr 3:88,461,065...88,477,032 		JBrowse link
negative regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within IMP (PMID:20705711) MGI PMID:20705711 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323 		JBrowse link
G Lzts1 leucine zipper, putative tumor suppressor 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:69,585,311...69,636,901
Ensembl chr 8:69,585,321...69,636,877 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in
acts_upstream_of_or_within		 IBA
ISO
IMP		 (PMID:25327288)
(PMID:16714284), (PMID:23274896)		 GO_Central
MGI		 PMID:16714284 PMID:23274896 PMID:25327288 GO_REF:0000033 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 acts_upstream_of_or_within IGI
IMP		 (PMID:17468177) MGI PMID:17468177 NCBI chr18:12,322,751...12,369,851
Ensembl chr18:12,322,749...12,369,457 		JBrowse link
G Nrbp2 nuclear receptor binding protein 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:75,957,364...75,963,539
Ensembl chr15:75,957,367...75,963,476 		JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Poldip2 polymerase (DNA-directed), delta interacting protein 2 acts_upstream_of_or_within IMP (PMID:24797518) MGI PMID:24797518 NCBI chr11:78,403,105...78,413,562
Ensembl chr11:78,403,019...78,413,562 		JBrowse link
G Qsox1 quiescin Q6 sulfhydryl oxidase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:155,653,901...155,688,645
Ensembl chr 1:155,651,775...155,688,635 		JBrowse link
G Smcr8 Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:60,668,351...60,679,113
Ensembl chr11:60,668,350...60,679,113 		JBrowse link
G Tsc1 TSC complex subunit 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 2:28,531,005...28,581,183
Ensembl chr 2:28,531,240...28,581,179 		JBrowse link
G Tsc2 TSC complex subunit 2 involved_in ISO RGD
MGI		 PMID:24599401 GO_REF:0000096 MGI:4417868 RGD:11568679 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604 		JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:118,150,477...118,181,086
Ensembl chr11:118,150,477...118,181,070 		JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain family 16, member A acts_upstream_of_or_within IMP (PMID:24949970) MGI PMID:24949970 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742 		JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Rnf41 ring finger protein 41 acts_upstream_of_or_within IGI (PMID:24949970) MGI PMID:24949970 NCBI chr10:128,247,485...128,277,310
Ensembl chr10:128,247,526...128,277,310 		JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within IMP (PMID:22044588) MGI PMID:22044588 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520 		JBrowse link
G Trp53 transformation related protein 53 acts_upstream_of_or_within IMP (PMID:22044588) MGI PMID:22044588 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tspo translocator protein involved_in IMP (MGI:5689082|PMID:25470454) ParkinsonsUK-UCL PMID:25470454 MGI:5689082 NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404 		JBrowse link
G Usp30 ubiquitin specific peptidase 30 involved_in ISO RGD
MGI		 PMID:24896179 GO_REF:0000096 MGI:4417868 RGD:13208875 NCBI chr 5:114,238,395...114,261,571
Ensembl chr 5:114,203,522...114,262,781 		JBrowse link
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps13c vacuolar protein sorting 13C involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:67,747,594...67,905,026
Ensembl chr 9:67,747,678...67,902,920 		JBrowse link
positive regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag3 BCL2-associated athanogene 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705 		JBrowse link
G Csnk2a1 casein kinase 2, alpha 1 polypeptide involved_in ISO (PMID:22017874) UniProt PMID:22017874 NCBI chr 2:152,068,468...152,123,772
Ensembl chr 2:152,068,759...152,123,772 		JBrowse link
G Hspb8 heat shock protein 8 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923 		JBrowse link
G Htt huntingtin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878 		JBrowse link
G Kat5 K(lysine) acetyltransferase 5 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:5,653,042...5,661,584
Ensembl chr19:5,653,042...5,660,265 		JBrowse link
G Zdhhc19 zinc finger, DHHC domain containing 19 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:32,315,059...32,326,032
Ensembl chr16:32,315,083...32,380,784 		JBrowse link
positive regulation of autophagosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg2a autophagy related 2A involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:6,291,508...6,312,332
Ensembl chr19:6,291,698...6,312,365 		JBrowse link
G Becn1 beclin 1, autophagy related involved_in ISO RGD
MGI		 PMID:25561470 GO_REF:0000096 MGI:4417868 RGD:11561937 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Elapor1 endosome-lysosome associated apoptosis and autophagy regulator 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:108,362,995...108,444,064
Ensembl chr 3:108,363,010...108,443,852 		JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:32,815,227...32,851,666
Ensembl chr 2:32,815,228...32,851,626 		JBrowse link
G Moap1 modulator of apoptosis 1 involved_in IMP
ISO		 (MGI:6810697|PMID:33783314) UniProt
MGI		 PMID:33783314 GO_REF:0000119 MGI:4834177 MGI:6810697 NCBI chr12:102,706,089...102,709,920
Ensembl chr12:102,708,489...102,709,920 		JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:18,847,066...19,003,101
Ensembl chr 2:18,847,066...19,002,937 		JBrowse link
G Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:97,605,983...97,635,530
Ensembl chr11:97,605,983...97,635,530 		JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase, type II, gamma involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:127,032,936...127,047,508
Ensembl chr10:127,032,936...127,047,454 		JBrowse link
G Rab3gap1 RAB3 GTPase activating protein subunit 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:127,796,492...127,871,612
Ensembl chr 1:127,796,510...127,871,605 		JBrowse link
G Rab3gap2 RAB3 GTPase activating protein subunit 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:184,936,287...185,018,953
Ensembl chr 1:184,936,314...185,018,956 		JBrowse link
G Ralb v-ral simian leukemia viral oncogene B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:119,398,035...119,432,512
Ensembl chr 1:119,398,035...119,432,524 		JBrowse link
G Sh3glb1 SH3-domain GRB2-like B1 (endophilin) involved_in IMP
ISO		 (MGI:5634888|PMID:21068542) UniProt
MGI		 PMID:21068542 GO_REF:0000119 MGI:4834177 MGI:5634888 NCBI chr 3:144,389,426...144,426,186
Ensembl chr 3:144,389,439...144,426,096 		JBrowse link
G Snx18 sorting nexin 18 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:113,728,715...113,755,100
Ensembl chr13:113,728,715...113,755,100 		JBrowse link
G Snx30 sorting nexin family member 30 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:59,805,137...59,904,740
Ensembl chr 4:59,805,840...59,904,737 		JBrowse link
G Snx4 sorting nexin 4 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr16:33,071,826...33,119,932
Ensembl chr16:33,071,812...33,120,639 		JBrowse link
G Snx7 sorting nexin 7 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:117,575,146...117,662,585
Ensembl chr 3:117,575,296...117,662,585 		JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:65,523,223...65,534,477
Ensembl chr 4:65,523,223...65,534,475 		JBrowse link
G Ulk1 unc-51 like kinase 1 involved_in ISO RGD
MGI		 PMID:23448468 GO_REF:0000096 MGI:4417868 RGD:13208863 NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963 		JBrowse link
G Wdr45 WD repeat domain 45 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:7,588,212...7,594,439
Ensembl chr  X:7,580,572...7,594,445 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:109,464,347...109,502,215
Ensembl chr11:109,464,157...109,502,793 		JBrowse link
positive regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenergic receptor, beta 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030 		JBrowse link
G Calcoco2 calcium binding and coiled-coil domain 2 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:95,990,195...96,015,362
Ensembl chr11:95,990,152...96,002,790 		JBrowse link
G Clec16a C-type lectin domain family 16, member A acts_upstream_of_or_within IMP (PMID:24949970) MGI PMID:24949970 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742 		JBrowse link
G Fyco1 FYVE and coiled-coil domain containing 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:123,618,565...123,681,110
Ensembl chr 9:123,618,565...123,680,964 		JBrowse link
G Igtp interferon gamma induced GTPase involved_in IDA
ISO		 (MGI:3721856|PMID:16940170) UniProt
MGI		 PMID:16940170 GO_REF:0000119 MGI:3721856 MGI:4834177 NCBI chr11:58,090,382...58,098,418
Ensembl chr11:58,090,382...58,098,417 		JBrowse link
G Irgm1 immunity-related GTPase family M member 1 involved_in IDA
ISO		 (MGI:3656111|PMID:16888103) UniProt
MGI		 PMID:16888103 GO_REF:0000119 MGI:3656111 MGI:4834177 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510 		JBrowse link
G Irgm2 immunity-related GTPase family M member 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:58,105,803...58,113,609
Ensembl chr11:58,090,444...58,113,608 		JBrowse link
G Smcr8 Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:60,668,351...60,679,113
Ensembl chr11:60,668,350...60,679,113 		JBrowse link
G Tom1 target of myb1 trafficking protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:75,760,326...75,796,749
Ensembl chr 8:75,760,333...75,796,749 		JBrowse link
positive regulation of lipophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenergic receptor, beta 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030 		JBrowse link
G Htt huntingtin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878 		JBrowse link
G Sesn2 sestrin 2 acts_upstream_of_or_within IMP (PMID:22958918) MGI PMID:22958918 NCBI chr 4:132,220,115...132,237,767
Ensembl chr 4:132,219,343...132,237,812 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr13:53,486,784...53,531,401
Ensembl chr13:53,486,784...53,531,433 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr12:87,351,832...87,435,129
Ensembl chr12:87,351,832...87,435,129 		JBrowse link
positive regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2/adenovirus E1B interacting protein 3 acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326 		JBrowse link
G C9orf72 C9orf72, member of C9orf72-SMCR8 complex involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:35,191,285...35,226,153
Ensembl chr 4:35,191,285...35,226,175 		JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005 		JBrowse link
G Epm2a epilepsy, progressive myoclonic epilepsy, type 2 gene alpha acts_upstream_of_or_within ISO
IGI
IMP		 (PMID:20453062) MGI PMID:20453062 GO_REF:0000008 NCBI chr10:11,218,435...11,335,408
Ensembl chr10:11,219,148...11,335,388 		JBrowse link
G Gnai3 G protein subunit alpha i3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:108,014,591...108,053,468
Ensembl chr 3:108,014,596...108,053,462 		JBrowse link
G Gpsm1 G-protein signalling modulator 1 (AGS3-like, C. elegans) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:26,204,623...26,238,249
Ensembl chr 2:26,205,527...26,238,249 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit acts_upstream_of_or_within IMP (PMID:19273585) MGI PMID:19273585 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within IMP (PMID:20705711) MGI PMID:20705711 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma involved_in IMP (MGI:5819337|PMID:23778976) ParkinsonsUK-UCL PMID:23778976 MGI:5819337 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460 		JBrowse link
G Il4 interleukin 4 involved_in IDA (MGI:5702366|PMID:26416964) UniProt PMID:26416964 MGI:5702366 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Kdr kinase insert domain protein receptor acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:57,899,711...57,952,860
Ensembl chr11:57,899,890...57,952,860 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in IMP (MGI:5819337|PMID:23778976) ParkinsonsUK-UCL PMID:23778976 MGI:5819337 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Pafah1b2 platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:45,876,609...45,923,988
Ensembl chr 9:45,874,157...45,923,988 		JBrowse link
G Pim2 proviral integration site 2 acts_upstream_of_or_within IMP (PMID:17476689) MGI PMID:17476689 NCBI chr  X:7,744,545...7,749,671
Ensembl chr  X:7,744,501...7,749,671 		JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Rab12 RAB12, member RAS oncogene family involved_in IMP (MGI:5574288|PMID:23357852) UniProt PMID:23357852 MGI:5574288 NCBI chr17:66,801,507...66,826,712
Ensembl chr17:66,801,507...66,826,724 		JBrowse link
G Rufy4 RUN and FYVE domain containing 4 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 1:74,163,768...74,187,389
Ensembl chr 1:74,164,700...74,187,382 		JBrowse link
G Scoc short coiled-coil protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:84,161,121...84,185,055
Ensembl chr 8:84,156,713...84,185,020 		JBrowse link
G Sesn1 sestrin 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:41,686,570...41,784,432
Ensembl chr10:41,685,931...41,784,420 		JBrowse link
G Sesn2 sestrin 2 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 4:132,220,115...132,237,767
Ensembl chr 4:132,219,343...132,237,812 		JBrowse link
G Sesn3 sestrin 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:14,187,597...14,237,430
Ensembl chr 9:14,186,363...14,244,397 		JBrowse link
G Sirt1 sirtuin 1 involved_in IDA
ISO		 (MGI:3776699|PMID:18296641), (MGI:4940431|PMID:21189328) UniProt
MGI		 PMID:18296641 PMID:21189328 GO_REF:0000119 MGI:3776699 MGI:4834177 MGI:4940431 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in IMP
IBA
ISO		 (MGI:6305034|PMID:30568238) UniProt
GO_Central
MGI		 PMID:30568238 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6305034 NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607 		JBrowse link
G Supt5 suppressor of Ty 5, DSIF elongation factor subunit involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:28,014,316...28,038,341
Ensembl chr 7:28,014,316...28,038,171 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692 		JBrowse link
G Trim13 tripartite motif-containing 13 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr14:61,835,675...61,847,736
Ensembl chr14:61,835,696...61,843,395 		JBrowse link
G Tsc1 TSC complex subunit 1 involved_in ISO RGD
MGI		 PMID:23435171 GO_REF:0000096 MGI:4417868 RGD:10448950 NCBI chr 2:28,531,005...28,581,183
Ensembl chr 2:28,531,240...28,581,179 		JBrowse link
G Tsc2 TSC complex subunit 2 involved_in
acts_upstream_of_or_within		 IMP
ISO		 (MGI:5819337|PMID:23778976)
(PMID:20453062)		 ParkinsonsUK-UCL
MGI		 PMID:20453062 PMID:23778976 GO_REF:0000119 MGI:4834177 MGI:5819337 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604 		JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:7,868,614...7,929,028
Ensembl chr18:7,868,832...7,929,028 		JBrowse link
G Wdr24 WD repeat domain 24 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:26,042,601...26,047,704
Ensembl chr17:26,042,601...26,047,704 		JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy/beclin 1 regulator 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:91,560,464...91,749,194
Ensembl chr 2:91,560,479...91,749,194 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:70,768,425...70,784,238
Ensembl chr 8:70,768,425...70,784,242 		JBrowse link
G Fbxo7 F-box protein 7 involved_in ISO MGI GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit involved_in IMP (MGI:3796473|PMID:18281291) ParkinsonsUK-UCL PMID:18281291 MGI:3796473 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Htt huntingtin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878 		JBrowse link
G Igtp interferon gamma induced GTPase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:58,090,382...58,098,418
Ensembl chr11:58,090,382...58,098,417 		JBrowse link
G Irgm1 immunity-related GTPase family M member 1 involved_in IMP
ISO		 (MGI:6705154|PMID:33510463) UniProt
MGI		 PMID:33510463 GO_REF:0000119 MGI:4834177 MGI:6705154 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510 		JBrowse link
G Irgm2 immunity-related GTPase family M member 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:58,105,803...58,113,609
Ensembl chr11:58,090,444...58,113,608 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in IMP (MGI:6388731|PMID:31919280) UniProt PMID:31919280 MGI:6388731 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO RGD
MGI		 PMID:28608965 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:13432560 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Slc25a4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 involved_in IDA (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321 		JBrowse link
G Slc25a5 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 involved_in IDA (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chr  X:36,059,250...36,062,461
Ensembl chr  X:36,059,304...36,062,460 		JBrowse link
G Vps13d vacuolar protein sorting 13D involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:144,597,619...144,921,598
Ensembl chr 4:144,699,192...144,921,575 		JBrowse link
positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vdac1 voltage-dependent anion channel 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224 		JBrowse link
positive regulation of xenophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igtp interferon gamma induced GTPase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:58,090,382...58,098,418
Ensembl chr11:58,090,382...58,098,417 		JBrowse link
G Irgm1 immunity-related GTPase family M member 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510 		JBrowse link
G Irgm2 immunity-related GTPase family M member 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:58,105,803...58,113,609
Ensembl chr11:58,090,444...58,113,608 		JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:32,815,227...32,851,666
Ensembl chr 2:32,815,228...32,851,626 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 acts_upstream_of_or_within IGI (PMID:22033934) MGI PMID:22033934 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within IMP (PMID:22033934) MGI PMID:22033934 NCBI chr 6:54,900,927...54,949,655
Ensembl chr 6:54,900,934...54,949,597 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within IMP (PMID:22033934) MGI PMID:22033934 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Optn optineurin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:5,023,902...5,069,210
Ensembl chr 2:5,025,453...5,068,862 		JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 acts_upstream_of_or_within IMP (PMID:22033934) MGI PMID:22033934 NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647 		JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:55,829,199...55,841,131
Ensembl chr14:55,829,165...55,841,150 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in IMP (MGI:5645201|PMID:21617041) ParkinsonsUK-UCL PMID:21617041 MGI:5645201 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within IMP (PMID:22033934) MGI PMID:22033934 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg12 autophagy related 12 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647 		JBrowse link
G Atg5 autophagy related 5 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287 		JBrowse link
G Clec16a C-type lectin domain family 16, member A involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IMP (MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:5698740 NCBI chr 7:126,170,571...126,184,991
Ensembl chr 7:126,170,379...126,184,989 		JBrowse link
G Tbc1d25 TBC1 domain family, member 25 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr  X:8,020,709...8,042,420
Ensembl chr  X:8,020,711...8,042,420 		JBrowse link
G Tecpr1 tectonin beta-propeller repeat containing 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:144,131,260...144,160,433
Ensembl chr 5:144,131,260...144,160,433 		JBrowse link
regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 involved_in ISO RGD
MGI		 PMID:31172217 GO_REF:0000096 MGI:4417868 RGD:329403053 NCBI chr 1:165,309,114...165,404,347
Ensembl chr 1:165,312,752...165,404,343 		JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like involved_in IGI (MGI:5616312|PMID:20200478) ParkinsonsUK-UCL PMID:20200478 MGI:5616312 NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326 		JBrowse link
G Csnk2a2 casein kinase 2, alpha prime polypeptide involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 8:96,172,724...96,215,505
Ensembl chr 8:96,172,724...96,216,667 		JBrowse link
G Cttn cortactin involved_in IMP (MGI:5616310|PMID:20457763) ParkinsonsUK-UCL PMID:20457763 MGI:5616310 NCBI chr 7:143,989,468...144,024,743
Ensembl chr 7:143,989,470...144,024,746 		JBrowse link
G Dnm1l dynamin 1-like involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823 		JBrowse link
G Fbxw7 F-box and WD-40 domain protein 7 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505 		JBrowse link
G Fkbp8 FK506 binding protein 8 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:70,980,371...70,987,978
Ensembl chr 8:70,980,374...70,987,978 		JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 1:64,769,717...64,776,907
Ensembl chr 1:64,769,717...64,776,910 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in IMP (MGI:5619462|PMID:21355049) ParkinsonsUK-UCL PMID:21355049 MGI:5619462 NCBI chr16:20,098,570...20,121,090
Ensembl chr16:20,098,568...20,121,137 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Srebf2 sterol regulatory element binding factor 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580 		JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr11:118,150,477...118,181,086
Ensembl chr11:118,150,477...118,181,070 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in IMP (MGI:5689082|PMID:25470454) ParkinsonsUK-UCL PMID:25470454 MGI:5689082 NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    cellular process 17593
      process utilizing autophagic mechanism 538
        autophagy 538
          macroautophagy 306
            regulation of macroautophagy 135
              negative regulation of macroautophagy + 33
              positive regulation of macroautophagy + 84
              regulation of aggrephagy + 8
              regulation of autophagosome maturation + 18
              regulation of lipophagy + 5
              regulation of mitophagy + 35
              regulation of reticulophagy + 0
              regulation of xenophagy + 12
Path 2
Term Annotations click to browse term
  biological_process 28573
    biological regulation 13112
      regulation of biological process 12722
        regulation of cellular process 12175
          regulation of cellular metabolic process 6139
            regulation of cellular catabolic process 774
              regulation of autophagy 318
                regulation of macroautophagy 135
                  negative regulation of macroautophagy + 33
                  positive regulation of macroautophagy + 84
                  regulation of aggrephagy + 8
                  regulation of autophagosome maturation + 18
                  regulation of lipophagy + 5
                  regulation of mitophagy + 35
                  regulation of reticulophagy + 0
                  regulation of xenophagy + 12
paths to the root