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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of macroautophagy
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Accession:GO:0016241 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of macroautophagy.
Synonyms:exact_synonym: regulation of starvation-induced autophagy



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regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg14 autophagy related 14 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:47,778,350...47,805,891
Ensembl chr14:47,778,350...47,808,106
JBrowse link
G Atp13a2 ATPase type 13A2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:140,711,812...140,734,641
Ensembl chr 4:140,714,184...140,734,641
JBrowse link
G Atp6v0a1 ATPase, H+ transporting, lysosomal V0 subunit A1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:100,899,262...100,954,545
Ensembl chr11:100,900,278...100,954,545
JBrowse link
G Becn1 beclin 1, autophagy related involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:7,796,355...7,814,284
Ensembl chr  X:7,796,359...7,814,128
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase catalytic subunit type 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:30,390,441...30,481,179
Ensembl chr18:30,405,800...30,481,179
JBrowse link
G Pik3r4 phosphoinositide-3-kinase regulatory subunit 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:105,520,156...105,564,854
Ensembl chr 9:105,520,177...105,564,856
JBrowse link
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit involved_in IDA (MGI:5619439|PMID:23332761) UniProt PMID:23332761 MGI:5619439 NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087
JBrowse link
G Ubqln1 ubiquilin 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr13:58,323,970...58,363,467
Ensembl chr13:58,323,970...58,363,467
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr  X:152,281,228...152,284,558
Ensembl chr  X:152,281,223...152,284,566
JBrowse link
G Ulk1 unc-51 like kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963
JBrowse link
negative regulation of autophagosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1, autophagy related acts_upstream_of_or_within IMP (MGI:5888970|PMID:27994061) MGI PMID:27994061 MGI:5888970 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Chmp4b charged multivesicular body protein 4B involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:154,498,946...154,536,703
Ensembl chr 2:154,493,625...154,536,705
JBrowse link
G Ehmt2 euchromatic histone lysine N-methyltransferase 2 acts_upstream_of_or_within IMP (MGI:5543871|PMID:23918802) MGI PMID:23918802 MGI:5543871 NCBI chr17:35,117,426...35,133,049
Ensembl chr17:35,117,445...35,133,028
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 (zygin I) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:36,732,694...36,790,222
Ensembl chr 9:36,733,160...36,790,220
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 (zygin II) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:78,676,641...78,725,581
Ensembl chr17:78,676,641...78,725,581
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323
JBrowse link
G Mtm1 X-linked myotubular myopathy gene 1 acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:5510937|PMID:23695157)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:21873635 PMID:23695157 MGI:5510937 MGI:6201960 NCBI chr  X:70,254,373...70,359,019
Ensembl chr  X:70,254,373...70,359,297
JBrowse link
G Nupr1 nuclear protein transcription regulator 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
JBrowse link
G Phf23 PHD finger protein 23 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr11:69,886,592...69,890,837
Ensembl chr11:69,886,603...69,890,835
JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
JBrowse link
G Scfd1 Sec1 family domain containing 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:51,424,296...51,496,887
Ensembl chr12:51,424,293...51,496,884
JBrowse link
G Sec22b SEC22 homolog B, vesicle trafficking protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:97,808,543...97,829,634
Ensembl chr 3:97,808,506...97,830,592
JBrowse link
G Smcr8 Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:60,668,351...60,679,113
Ensembl chr11:60,668,350...60,679,113
JBrowse link
G Tmem39a transmembrane protein 39a involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr16:38,379,060...38,412,524
Ensembl chr16:38,379,060...38,412,524
JBrowse link
negative regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain family 16, member A involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742
JBrowse link
G Phf23 PHD finger protein 23 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr11:69,886,592...69,890,837
Ensembl chr11:69,886,603...69,890,835
JBrowse link
G Rubcn RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr16:32,642,072...32,698,121
Ensembl chr16:32,642,073...32,698,136
JBrowse link
G Tmem39a transmembrane protein 39a involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr16:38,379,060...38,412,524
Ensembl chr16:38,379,060...38,412,524
JBrowse link
G Ubqln4 ubiquilin 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:88,460,984...88,477,032
Ensembl chr 3:88,461,065...88,477,032
JBrowse link
negative regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within IMP (MGI:5430482|PMID:20705711) MGI PMID:20705711 MGI:5430482 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323
JBrowse link
G Lzts1 leucine zipper, putative tumor suppressor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:69,585,311...69,636,901
Ensembl chr 8:69,585,321...69,636,877
JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within
involved_in
ISO
IBA
IMP
(MGI:5615337|PMID:25327288)
(MGI:6201960|PMID:21873635)
(MGI:3690270|PMID:16714284), (MGI:5563734|PMID:23274896)
MGI
GO_Central
PMID:16714284 PMID:21873635 PMID:23274896 PMID:25327288 MGI:3690270 MGI:5563734 MGI:5615337 MGI:6201960 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 acts_upstream_of_or_within IGI
IMP
(MGI:3723543|PMID:17468177) MGI PMID:17468177 MGI:3723543 NCBI chr18:12,322,751...12,369,851
Ensembl chr18:12,322,749...12,369,457
JBrowse link
G Nrbp2 nuclear receptor binding protein 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:75,957,364...75,963,539
Ensembl chr15:75,957,367...75,963,476
JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
JBrowse link
G Poldip2 polymerase (DNA-directed), delta interacting protein 2 acts_upstream_of_or_within IMP (MGI:5588624|PMID:24797518) MGI PMID:24797518 MGI:5588624 NCBI chr11:78,403,007...78,413,566
Ensembl chr11:78,403,019...78,413,562
JBrowse link
G Qsox1 quiescin Q6 sulfhydryl oxidase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:155,653,901...155,688,645
Ensembl chr 1:155,651,775...155,688,635
JBrowse link
G Smcr8 Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:60,668,351...60,679,113
Ensembl chr11:60,668,350...60,679,113
JBrowse link
G Smg1 SMG1 nonsense mediated mRNA decay associated PI3K related kinase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:117,730,531...117,843,026
Ensembl chr 7:117,730,531...117,842,893
JBrowse link
G Tsc1 TSC complex subunit 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 2:28,531,005...28,581,184
Ensembl chr 2:28,531,240...28,581,179
JBrowse link
G Tsc2 TSC complex subunit 2 involved_in ISO RGD
MGI
PMID:24599401 GO_REF:0000096 MGI:4417868 RGD:11568679 NCBI chr17:24,814,790...24,851,607
Ensembl chr17:24,814,790...24,851,604
JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:118,150,477...118,181,086
Ensembl chr11:118,150,477...118,181,070
JBrowse link
negative regulation of macroautophagy by TORC1 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain family 16, member A involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742
JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain family 16, member A acts_upstream_of_or_within IMP (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742
JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
JBrowse link
G Rnf41 ring finger protein 41 acts_upstream_of_or_within IGI (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr10:128,247,485...128,277,310
Ensembl chr10:128,247,526...128,277,310
JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within IMP (MGI:5319065|PMID:22044588) MGI PMID:22044588 MGI:5319065 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520
JBrowse link
G Trp53 transformation related protein 53 acts_upstream_of_or_within IMP (MGI:5319065|PMID:22044588) MGI PMID:22044588 MGI:5319065 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Usp30 ubiquitin specific peptidase 30 involved_in ISO RGD
MGI
PMID:24896179 GO_REF:0000096 MGI:4417868 RGD:13208875 NCBI chr 5:114,238,344...114,261,571
Ensembl chr 5:114,203,522...114,262,781
JBrowse link
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps13c vacuolar protein sorting 13C involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:67,747,594...67,905,026
Ensembl chr 9:67,747,678...67,902,920
JBrowse link
positive regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag3 BCL2-associated athanogene 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705
JBrowse link
G Hspb8 heat shock protein 8 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923
JBrowse link
G Htt huntingtin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878
JBrowse link
positive regulation of autophagosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg2a autophagy related 2A involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:6,291,508...6,312,334
Ensembl chr19:6,291,698...6,312,365
JBrowse link
G Becn1 beclin 1, autophagy related involved_in ISO RGD
MGI
PMID:25561470 GO_REF:0000096 MGI:4417868 RGD:11561937 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Elapor1 endosome-lysosome associated apoptosis and autophagy regulator 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:108,362,995...108,444,064
Ensembl chr 3:108,363,010...108,443,852
JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:32,815,227...32,851,666
Ensembl chr 2:32,815,228...32,851,626
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO
IMP
(MGI:6810697|PMID:33783314) MGI
UniProt
PMID:33783314 GO_REF:0000096 MGI:4834177 MGI:6810697 NCBI chr12:102,706,089...102,709,920
Ensembl chr12:102,708,489...102,709,920
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:18,847,066...19,003,101
Ensembl chr 2:18,847,066...19,002,937
JBrowse link
G Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:97,605,983...97,635,530
Ensembl chr11:97,605,983...97,635,530
JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase, type II, gamma involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:127,032,936...127,047,508
Ensembl chr10:127,032,936...127,047,454
JBrowse link
G Rab3gap1 RAB3 GTPase activating protein subunit 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:127,796,492...127,871,613
Ensembl chr 1:127,796,510...127,871,605
JBrowse link
G Rab3gap2 RAB3 GTPase activating protein subunit 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:184,936,287...185,018,958
Ensembl chr 1:184,936,314...185,018,956
JBrowse link
G Ralb v-ral simian leukemia viral oncogene B involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:119,398,035...119,432,512
Ensembl chr 1:119,398,035...119,432,524
JBrowse link
G Sh3glb1 SH3-domain GRB2-like B1 (endophilin) involved_in ISO
IMP
(MGI:5634888|PMID:21068542) MGI
UniProt
PMID:21068542 GO_REF:0000096 MGI:4834177 MGI:5634888 NCBI chr 3:144,389,426...144,426,186
Ensembl chr 3:144,389,439...144,426,096
JBrowse link
G Snx18 sorting nexin 18 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:113,728,715...113,755,100
Ensembl chr13:113,728,715...113,755,100
JBrowse link
G Snx30 sorting nexin family member 30 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 4:59,805,137...59,904,740
Ensembl chr 4:59,805,840...59,904,737
JBrowse link
G Snx4 sorting nexin 4 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr16:33,071,826...33,119,932
Ensembl chr16:33,071,812...33,120,639
JBrowse link
G Snx7 sorting nexin 7 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 3:117,575,146...117,662,585
Ensembl chr 3:117,575,296...117,662,585
JBrowse link
G Ulk1 unc-51 like kinase 1 involved_in ISO RGD
MGI
PMID:23448468 GO_REF:0000096 MGI:4417868 RGD:13208863 NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963
JBrowse link
G Wdr45 WD repeat domain 45 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:7,588,193...7,594,440
Ensembl chr  X:7,580,572...7,594,445
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:109,464,347...109,502,215
Ensembl chr11:109,464,157...109,502,793
JBrowse link
positive regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenergic receptor, beta 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
JBrowse link
G Calcoco2 calcium binding and coiled-coil domain 2 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr11:95,989,742...96,015,362
Ensembl chr11:95,990,152...96,002,790
JBrowse link
G Clec16a C-type lectin domain family 16, member A acts_upstream_of_or_within IMP (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742
JBrowse link
G Fyco1 FYVE and coiled-coil domain containing 1 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 9:123,618,565...123,681,110
Ensembl chr 9:123,618,565...123,680,964
JBrowse link
G Igtp interferon gamma induced GTPase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:58,090,382...58,098,418
Ensembl chr11:58,090,382...58,098,417
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 involved_in IDA
ISO
(MGI:3656111|PMID:16888103) UniProt
MGI
PMID:16888103 GO_REF:0000096 MGI:3656111 MGI:4834177 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510
JBrowse link
G Irgm2 immunity-related GTPase family M member 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:58,105,803...58,113,609
Ensembl chr11:58,090,444...58,113,608
JBrowse link
G Smcr8 Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:60,668,351...60,679,113
Ensembl chr11:60,668,350...60,679,113
JBrowse link
positive regulation of lipophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenergic receptor, beta 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
JBrowse link
G Htt huntingtin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878
JBrowse link
G Sesn2 sestrin 2 acts_upstream_of_or_within IMP (MGI:5444071|PMID:22958918) MGI PMID:22958918 MGI:5444071 NCBI chr 4:132,220,115...132,237,767
Ensembl chr 4:132,219,343...132,237,812
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr13:53,486,784...53,531,453
Ensembl chr13:53,486,784...53,531,433
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr12:87,351,832...87,435,129
Ensembl chr12:87,351,832...87,435,129
JBrowse link
positive regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2/adenovirus E1B interacting protein 3 acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326
JBrowse link
G C9orf72 C9orf72, member of C9orf72-SMCR8 complex involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:35,191,285...35,226,153
Ensembl chr 4:35,191,285...35,226,175
JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005
JBrowse link
G Epm2a epilepsy, progressive myoclonic epilepsy, type 2 gene alpha acts_upstream_of_or_within ISO
IGI
IMP
(MGI:4457987|PMID:20453062) MGI PMID:20453062 GO_REF:0000008 MGI:2154458 MGI:4457987 NCBI chr10:11,218,435...11,335,408
Ensembl chr10:11,219,148...11,335,388
JBrowse link
G Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:108,014,591...108,053,468
Ensembl chr 3:108,014,596...108,053,462
JBrowse link
G Gpsm1 G-protein signalling modulator 1 (AGS3-like, C. elegans) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:26,204,623...26,238,249
Ensembl chr 2:26,205,527...26,238,249
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit acts_upstream_of_or_within IMP (MGI:3847365|PMID:19273585) MGI PMID:19273585 MGI:3847365 NCBI chr12:73,948,098...73,994,328
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within IMP (MGI:5430482|PMID:20705711) MGI PMID:20705711 MGI:5430482 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma involved_in IMP (MGI:5819337|PMID:23778976) ParkinsonsUK-UCL PMID:23778976 MGI:5819337 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460
JBrowse link
G Il4 interleukin 4 involved_in IDA
IBA
(MGI:5702366|PMID:26416964)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
PMID:21873635 PMID:26416964 MGI:5702366 MGI:6201960 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Kdr kinase insert domain protein receptor acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr 5:76,093,487...76,139,885
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:57,899,711...57,952,860
Ensembl chr11:57,899,890...57,952,860
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in IMP (MGI:5819337|PMID:23778976) ParkinsonsUK-UCL PMID:23778976 MGI:5819337 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467
JBrowse link
G Pafah1b2 platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:45,876,609...45,923,988
Ensembl chr 9:45,874,157...45,923,988
JBrowse link
G Pim2 proviral integration site 2 acts_upstream_of_or_within IMP (MGI:4361989|PMID:17476689) MGI PMID:17476689 MGI:4361989 NCBI chr  X:7,744,545...7,749,671
Ensembl chr  X:7,744,501...7,749,671
JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
JBrowse link
G Rab12 RAB12, member RAS oncogene family involved_in IMP (MGI:5574288|PMID:23357852) UniProt PMID:23357852 MGI:5574288 NCBI chr17:66,801,507...66,826,665
Ensembl chr17:66,801,507...66,826,724
JBrowse link
G Rufy4 RUN and FYVE domain containing 4 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 1:74,163,768...74,187,389
Ensembl chr 1:74,164,700...74,187,382
JBrowse link
G Scoc short coiled-coil protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:84,161,121...84,185,055
Ensembl chr 8:84,156,713...84,185,020
JBrowse link
G Sesn1 sestrin 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr10:41,686,570...41,784,432
Ensembl chr10:41,685,931...41,784,420
JBrowse link
G Sesn2 sestrin 2 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 4:132,220,115...132,237,767
Ensembl chr 4:132,219,343...132,237,812
JBrowse link
G Sesn3 sestrin 3 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:14,187,597...14,237,430
Ensembl chr 9:14,186,363...14,244,397
JBrowse link
G Sirt1 sirtuin 1 involved_in IDA
ISO
(MGI:3776699|PMID:18296641), (MGI:4940431|PMID:21189328) UniProt
MGI
PMID:18296641 PMID:21189328 GO_REF:0000096 MGI:3776699 MGI:4834177 MGI:4940431 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in IBA
ISO
IMP
(MGI:6201960|PMID:21873635)
(MGI:6305034|PMID:30568238)
GO_Central
MGI
UniProt
PMID:21873635 PMID:30568238 GO_REF:0000096 MGI:4834177 MGI:6201960 MGI:6305034 NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607
JBrowse link
G Supt5 suppressor of Ty 5, DSIF elongation factor subunit involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:28,014,316...28,038,341
Ensembl chr 7:28,014,316...28,038,171
JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692
JBrowse link
G Trim13 tripartite motif-containing 13 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr14:61,835,675...61,847,736
Ensembl chr14:61,835,696...61,843,395
JBrowse link
G Tsc1 TSC complex subunit 1 involved_in ISO RGD
MGI
PMID:23435171 GO_REF:0000096 MGI:4417868 RGD:10448950 NCBI chr 2:28,531,005...28,581,184
Ensembl chr 2:28,531,240...28,581,179
JBrowse link
G Tsc2 TSC complex subunit 2 involved_in
acts_upstream_of_or_within
ISO
IMP
(MGI:5819337|PMID:23778976)
(MGI:4457987|PMID:20453062)
MGI
ParkinsonsUK-UCL
PMID:20453062 PMID:23778976 GO_REF:0000096 MGI:4457987 MGI:4834177 MGI:5819337 NCBI chr17:24,814,790...24,851,607
Ensembl chr17:24,814,790...24,851,604
JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:7,868,614...7,929,028
Ensembl chr18:7,868,832...7,929,028
JBrowse link
G Wdr24 WD repeat domain 24 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr17:26,042,601...26,047,704
Ensembl chr17:26,042,601...26,047,704
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy/beclin 1 regulator 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:91,560,464...91,749,194
Ensembl chr 2:91,560,479...91,749,194
JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:70,768,425...70,784,238
Ensembl chr 8:70,768,425...70,784,242
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO RGD
MGI
PMID:28608965 GO_REF:0000096 MGI:4417868 RGD:13432560 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
JBrowse link
G Slc25a4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 involved_in IDA (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321
JBrowse link
G Slc25a5 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 involved_in IDA (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chr  X:36,059,250...36,062,461
Ensembl chr  X:36,059,304...36,062,460
JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chr11:52,251,678...52,280,224
Ensembl chr11:52,251,687...52,280,224
JBrowse link
G Vps13d vacuolar protein sorting 13D involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:144,597,619...144,921,598
Ensembl chr 4:144,699,192...144,921,575
JBrowse link
positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vdac1 voltage-dependent anion channel 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:52,251,678...52,280,224
Ensembl chr11:52,251,687...52,280,224
JBrowse link
positive regulation of xenophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:32,815,227...32,851,666
Ensembl chr 2:32,815,228...32,851,626
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 acts_upstream_of_or_within IGI (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within IMP (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr 6:54,900,927...54,949,655
Ensembl chr 6:54,900,934...54,949,597
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within IMP (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102
JBrowse link
G Optn optineurin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:5,023,902...5,069,210
Ensembl chr 2:5,025,453...5,068,862
JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 acts_upstream_of_or_within IMP (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647
JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:55,829,199...55,841,131
Ensembl chr14:55,829,165...55,841,150
JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in IMP (MGI:5645201|PMID:21617041) ParkinsonsUK-UCL PMID:21617041 MGI:5645201 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692
JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within IMP (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg12 autophagy related 12 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647
JBrowse link
G Atg5 autophagy related 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
JBrowse link
G Clec16a C-type lectin domain family 16, member A involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742
JBrowse link
G Cln3 ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) involved_in IMP (MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:5698740 NCBI chr 7:126,170,379...126,184,989
Ensembl chr 7:126,170,379...126,184,989
JBrowse link
G Tbc1d25 TBC1 domain family, member 25 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr  X:8,020,709...8,042,420
Ensembl chr  X:8,020,711...8,042,420
JBrowse link
G Tecpr1 tectonin beta-propeller repeat containing 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:144,131,260...144,160,433
Ensembl chr 5:144,131,260...144,160,433
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28739
    cellular process 17696
      process utilizing autophagic mechanism 499
        autophagy 499
          macroautophagy 259
            regulation of macroautophagy 118
              negative regulation of macroautophagy + 32
              positive regulation of macroautophagy + 78
              regulation of aggrephagy + 3
              regulation of autophagosome maturation + 17
              regulation of lipophagy + 5
              regulation of mitophagy + 14
              regulation of reticulophagy + 0
              regulation of xenophagy + 9
Path 2
Term Annotations click to browse term
  biological_process 28739
    biological regulation 13608
      regulation of biological process 12946
        regulation of cellular process 12191
          regulation of cellular metabolic process 5717
            regulation of cellular catabolic process 784
              regulation of autophagy 304
                regulation of macroautophagy 118
                  negative regulation of macroautophagy + 32
                  positive regulation of macroautophagy + 78
                  regulation of aggrephagy + 3
                  regulation of autophagosome maturation + 17
                  regulation of lipophagy + 5
                  regulation of mitophagy + 14
                  regulation of reticulophagy + 0
                  regulation of xenophagy + 9
paths to the root