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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of macroautophagy
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Accession:GO:0016241 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of macroautophagy.
Synonyms:exact_synonym: regulation of starvation-induced autophagy


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regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg14 autophagy related 14 involved_in ISO (PMID:10625637) ComplexPortal PMID:10625637 NCBI chrNW_004955466:13,898,311...13,972,506
Ensembl chrNW_004955466:13,898,298...13,972,506
JBrowse link
G Atp13a2 ATPase cation transporting 13A2 involved_in ISO (PMID:22198378) ParkinsonsUK-UCL PMID:22198378 NCBI chrNW_004955527:1,805,854...1,823,623
Ensembl chrNW_004955527:1,806,009...1,823,344
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 involved_in ISO (PMID:22982048) ParkinsonsUK-UCL PMID:22982048 NCBI chrNW_004955451:16,396,287...16,442,596
Ensembl chrNW_004955451:16,396,287...16,444,932
JBrowse link
G Becn1 beclin 1 involved_in ISO (PMID:10625637) ComplexPortal PMID:10625637 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO (PMID:16192271) BHF-UCL PMID:16192271 NCBI chrNW_004955543:348,314...378,391
Ensembl chrNW_004955543:348,019...378,071
JBrowse link
G Mtmr8 myotubularin related protein 8 involved_in ISO (PMID:32915229) FlyBase PMID:32915229 NCBI chrNW_004955475:4,358,264...4,391,349 JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase catalytic subunit type 3 involved_in ISO (PMID:10625637) ComplexPortal PMID:10625637 NCBI chrNW_004955402:28,081,150...28,195,305
Ensembl chrNW_004955402:28,081,098...28,196,252
JBrowse link
G Pik3r4 phosphoinositide-3-kinase regulatory subunit 4 involved_in ISO (PMID:10625637) ComplexPortal PMID:10625637 NCBI chrNW_004955501:7,604,934...7,681,947
Ensembl chrNW_004955501:7,604,501...7,681,947
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in ISO (MGI:5619439|PMID:23332761) UniProt PMID:23332761 MGI:5619439 NCBI chrNW_004955464:2,996,608...3,062,197
Ensembl chrNW_004955464:3,003,837...3,062,197
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:20529957) UniProt PMID:20529957 NCBI chrNW_004955475:3,260,209...3,263,586
Ensembl chrNW_004955475:3,260,503...3,262,380
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 involved_in ISO (PMID:20921139) UniProt PMID:20921139 NCBI chrNW_004955482:760,200...777,133
Ensembl chrNW_004955482:761,811...777,133
JBrowse link
negative regulation of autophagosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 acts_upstream_of_or_within ISO (MGI:5888970|PMID:27994061) MGI PMID:27994061 MGI:5888970 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
JBrowse link
G Chmp4b charged multivesicular body protein 4B involved_in ISO (PMID:21975012) UniProt PMID:21975012 NCBI chrNW_004955422:27,482,239...27,526,798
Ensembl chrNW_004955422:27,478,698...27,526,575
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 acts_upstream_of_or_within ISO (MGI:5543871|PMID:23918802) MGI PMID:23918802 MGI:5543871 NCBI chrNW_004955437:396,736...411,144
Ensembl chrNW_004955437:396,742...411,144
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 involved_in ISO (PMID:25495476) GO_Central PMID:25495476 NCBI chrNW_004955412:26,477,995...26,530,686
Ensembl chrNW_004955412:26,477,301...26,531,354
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 involved_in ISO (PMID:25495476) GO_Central PMID:25495476 NCBI chrNW_004955441:4,421,936...4,456,070 JBrowse link
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (PMID:23916833) ParkinsonsUK-UCL PMID:23916833 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923
JBrowse link
G Mtm1 myotubularin 1 acts_upstream_of_or_within ISO (MGI:5510937|PMID:23695157) MGI PMID:23695157 MGI:5510937 NCBI chrNW_004955498:6,329,402...6,444,708
Ensembl chrNW_004955498:6,329,275...6,445,169
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO (PMID:20181828) UniProt PMID:20181828 NCBI chrNW_004955493:6,746,380...6,747,763
Ensembl chrNW_004955493:6,746,380...6,747,763
JBrowse link
G Phf23 PHD finger protein 23 involved_in ISO (PMID:25484098) GO_Central PMID:25484098 NCBI chrNW_004955467:9,671,133...9,675,434
Ensembl chrNW_004955467:9,671,133...9,675,434
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19279012) ParkinsonsUK-UCL PMID:19279012 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125
JBrowse link
G Scfd1 sec1 family domain containing 1 involved_in ISO (PMID:21242315) UniProt PMID:21242315 NCBI chrNW_004955409:29,805,909...29,903,208
Ensembl chrNW_004955409:29,805,909...29,903,208
JBrowse link
G Sec22b SEC22 homolog B, vesicle trafficking protein involved_in ISO (PMID:21242315) UniProt PMID:21242315 NCBI chrNW_004955568:1,559,519...1,587,782
Ensembl chrNW_004955568:1,559,452...1,587,782
JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit involved_in ISO (PMID:28195531) HGNC PMID:28195531 NCBI chrNW_004955478:11,002,174...11,015,123
Ensembl chrNW_004955478:11,002,174...11,015,123
JBrowse link
G Tmem39a transmembrane protein 39A involved_in ISO (PMID:31806350) UniProt PMID:31806350 NCBI chrNW_004955427:19,118,631...19,184,315
Ensembl chrNW_004955427:19,133,434...19,184,344
JBrowse link
negative regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A involved_in ISO (PMID:28223137) UniProt PMID:28223137 NCBI chrNW_004955442:7,369,616...7,584,052
Ensembl chrNW_004955442:7,368,952...7,584,703
JBrowse link
G Phf23 PHD finger protein 23 involved_in ISO (PMID:25484098) GO_Central PMID:25484098 NCBI chrNW_004955467:9,671,133...9,675,434
Ensembl chrNW_004955467:9,671,133...9,675,434
JBrowse link
G Rubcn rubicon autophagy regulator involved_in ISO (PMID:21062745) UniProt PMID:21062745 NCBI chrNW_004955420:12,124,193...12,187,154
Ensembl chrNW_004955420:12,123,450...12,187,154
JBrowse link
G Tmem39a transmembrane protein 39A involved_in ISO (PMID:31806350) UniProt PMID:31806350 NCBI chrNW_004955427:19,118,631...19,184,315
Ensembl chrNW_004955427:19,133,434...19,184,344
JBrowse link
G Ubqln4 ubiquilin 4 involved_in ISO (PMID:23459205) UniProt PMID:23459205 NCBI chrNW_004955545:2,218,794...2,236,665
Ensembl chrNW_004955545:2,220,548...2,236,646
JBrowse link
negative regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within ISO (MGI:5430482|PMID:20705711) MGI PMID:20705711 MGI:5430482 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979
JBrowse link
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (PMID:19640926) ParkinsonsUK-UCL PMID:19640926 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923
JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 involved_in ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chrNW_004955403:43,909,722...43,962,965
Ensembl chrNW_004955403:43,909,681...43,962,971
JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO (MGI:3690270|PMID:16714284), (MGI:5563734|PMID:23274896)
(PMID:25327288)
MGI PMID:16714284 PMID:23274896 PMID:25327288 MGI:3690270 MGI:5563734 NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 acts_upstream_of_or_within ISO (MGI:3723543|PMID:17468177) MGI PMID:17468177 MGI:3723543 NCBI chrNW_004955402:11,699,434...11,742,899
Ensembl chrNW_004955402:11,699,434...11,742,899
JBrowse link
G Nrbp2 nuclear receptor binding protein 2 involved_in ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chrNW_004955454:2,500,360...2,507,372 JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19279012) ParkinsonsUK-UCL PMID:19279012 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125
JBrowse link
G Poldip2 DNA polymerase delta interacting protein 2 acts_upstream_of_or_within ISO (MGI:5588624|PMID:24797518) MGI PMID:24797518 MGI:5588624 NCBI chrNW_004955481:4,776,721...4,785,817
Ensembl chrNW_004955481:4,776,721...4,785,817
JBrowse link
G Qsox1 quiescin sulfhydryl oxidase 1 involved_in ISO (PMID:24475161) CACAO PMID:24475161 NCBI chrNW_004955406:19,363,938...19,402,134 JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit involved_in ISO (PMID:28195531) HGNC PMID:28195531 NCBI chrNW_004955478:11,002,174...11,015,123
Ensembl chrNW_004955478:11,002,174...11,015,123
JBrowse link
G Tsc1 TSC complex subunit 1 involved_in ISO PMID:23435171 ParkinsonsUK-UCL PMID:23435171 RGD:10448950 NCBI chrNW_004955513:2,197,037...2,244,992
Ensembl chrNW_004955513:2,197,037...2,244,992
JBrowse link
G Tsc2 TSC complex subunit 2 ISO RGD PMID:24599401 RGD:11568679 NCBI chrNW_004955442:15,178,356...15,216,978
Ensembl chrNW_004955442:15,178,487...15,216,362
JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO (PMID:22622177) UniProt PMID:22622177 NCBI chrNW_004955506:3,824,598...3,861,919
Ensembl chrNW_004955506:3,824,556...3,862,098
JBrowse link
negative regulation of macroautophagy by TORC1 signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A involved_in ISO (PMID:28223137) UniProt PMID:28223137 NCBI chrNW_004955442:7,369,616...7,584,052
Ensembl chrNW_004955442:7,368,952...7,584,703
JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chrNW_004955442:7,369,616...7,584,052
Ensembl chrNW_004955442:7,368,952...7,584,703
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19279012) ParkinsonsUK-UCL PMID:19279012 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125
JBrowse link
G Rnf41 ring finger protein 41 acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chrNW_004955458:3,799,450...3,833,269
Ensembl chrNW_004955458:3,799,450...3,833,263
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:5319065|PMID:22044588) MGI PMID:22044588 MGI:5319065 NCBI chrNW_004955413:2,129,719...2,153,873
Ensembl chrNW_004955413:2,129,678...2,154,380
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:5319065|PMID:22044588) MGI PMID:22044588 MGI:5319065 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928
JBrowse link
G Usp30 ubiquitin specific peptidase 30 ISO RGD PMID:24896179 RGD:13208875 NCBI chrNW_004955455:10,234,779...10,257,959
Ensembl chrNW_004955455:10,192,426...10,257,951
JBrowse link
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps13c vacuolar protein sorting 13 homolog C involved_in ISO (PMID:26942284) ParkinsonsUK-UCL PMID:26942284 NCBI chrNW_004955450:13,016,933...13,178,797
Ensembl chrNW_004955450:13,016,950...13,174,990
JBrowse link
positive regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag3 BAG cochaperone 3 involved_in ISO (PMID:18006506) ARUK-UCL PMID:18006506 NCBI chrNW_004955551:446,322...468,329
Ensembl chrNW_004955551:446,605...469,207
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 involved_in ISO (PMID:18006506) ARUK-UCL PMID:18006506 NCBI chrNW_004955455:12,290,884...12,304,588
Ensembl chrNW_004955455:12,290,587...12,304,656
JBrowse link
G Htt huntingtin involved_in ISO (PMID:25686248) ParkinsonsUK-UCL PMID:25686248 NCBI chrNW_004955514:1,906,189...2,042,357
Ensembl chrNW_004955514:1,906,502...2,038,889
JBrowse link
positive regulation of autophagosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg2a autophagy related 2A involved_in ISO (PMID:30952800), (PMID:31271352) UniProt PMID:30952800 PMID:31271352 NCBI chrNW_004955422:20,261,749...20,290,879
Ensembl chrNW_004955422:20,271,330...20,291,875
JBrowse link
G Becn1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
JBrowse link
G Elapor1 endosome-lysosome associated apoptosis and autophagy regulator 1 involved_in ISO (PMID:21072319) BHF-UCL PMID:21072319 NCBI chrNW_004955435:12,531,651...12,626,969
Ensembl chrNW_004955435:12,531,642...12,627,874
JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO (PMID:25484098) GO_Central PMID:25484098 NCBI chrNW_004955419:1,121,127...1,154,356
Ensembl chrNW_004955419:1,121,127...1,154,356
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in ISO (PMID:25578879) ParkinsonsUK-UCL PMID:25578879 NCBI chrNW_004955429:6,231,135...6,399,672
Ensembl chrNW_004955429:6,336,355...6,399,672
JBrowse link
G Pip4k2b phosphatidylinositol-5-phosphate 4-kinase type 2 beta involved_in ISO (PMID:25578879) ParkinsonsUK-UCL PMID:25578879 NCBI chrNW_004955451:13,842,814...13,856,301
Ensembl chrNW_004955451:13,842,814...13,856,302
JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase type 2 gamma involved_in ISO (PMID:25578879) ParkinsonsUK-UCL PMID:25578879 NCBI chrNW_004955458:5,315,083...5,327,617
Ensembl chrNW_004955458:5,315,376...5,327,617
JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 involved_in ISO (PMID:25495476) GO_Central PMID:25495476 NCBI chrNW_004955440:2,551,015...2,645,938
Ensembl chrNW_004955440:2,550,982...2,646,331
JBrowse link
G Rab3gap2 RAB3 GTPase activating non-catalytic protein subunit 2 involved_in ISO (PMID:25495476) GO_Central PMID:25495476 NCBI chrNW_004955520:3,411,504...3,483,703
Ensembl chrNW_004955520:3,411,770...3,483,413
JBrowse link
G Ralb RAS like proto-oncogene B involved_in ISO (PMID:24056301) UniProt PMID:24056301 NCBI chrNW_004955459:9,533,081...9,574,464
Ensembl chrNW_004955459:9,531,538...9,574,766
JBrowse link
G Sh3glb1 SH3 domain containing GRB2 like, endophilin B1 involved_in ISO (PMID:21068542)
(MGI:5634888|PMID:21068542)
UniProt PMID:21068542 MGI:5634888 NCBI chrNW_004955423:7,393,186...7,414,199
Ensembl chrNW_004955423:7,393,186...7,423,903
JBrowse link
G Snx18 sorting nexin 18 involved_in ISO (PMID:29437695) UniProt PMID:29437695 NCBI chrNW_004955446:13,043,821...13,067,933
Ensembl chrNW_004955446:13,043,821...13,067,933
JBrowse link
G Snx30 sorting nexin family member 30 involved_in ISO (PMID:32513819) UniProt PMID:32513819 NCBI chrNW_004955419:14,567,317...14,645,442
Ensembl chrNW_004955419:14,567,317...14,619,637
JBrowse link
G Snx4 sorting nexin 4 involved_in ISO (PMID:32513819), (PMID:33468622) UniProt PMID:32513819 PMID:33468622 NCBI chrNW_004955427:24,520,125...24,579,589
Ensembl chrNW_004955427:24,520,125...24,579,589
JBrowse link
G Snx7 sorting nexin 7 involved_in ISO (PMID:32513819) UniProt PMID:32513819 NCBI chrNW_004955435:3,481,304...3,543,801
Ensembl chrNW_004955435:3,477,496...3,543,886
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 ISO RGD PMID:23448468 RGD:13208863 NCBI chrNW_004955482:760,200...777,133
Ensembl chrNW_004955482:761,811...777,133
JBrowse link
G Wdr45 WD repeat domain 45 involved_in ISO (PMID:31271352) UniProt PMID:31271352 NCBI chrNW_004955543:597,796...604,163
Ensembl chrNW_004955543:597,814...603,963
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 involved_in ISO (PMID:31271352) UniProt PMID:31271352 NCBI chrNW_004955478:4,309,975...4,341,107
Ensembl chrNW_004955478:4,309,880...4,343,934
JBrowse link
positive regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in ISO (PMID:23708524) GO_Central PMID:23708524 NCBI chrNW_004955415:5,515,157...5,517,198
Ensembl chrNW_004955415:5,515,697...5,516,980
JBrowse link
G Calcoco2 calcium binding and coiled-coil domain 2 involved_in ISO (PMID:25771791) GO_Central PMID:25771791 NCBI chrNW_004955451:12,443,262...12,469,608
Ensembl chrNW_004955451:12,443,796...12,469,857
JBrowse link
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chrNW_004955442:7,369,616...7,584,052
Ensembl chrNW_004955442:7,368,952...7,584,703
JBrowse link
G Fyco1 FYVE and coiled-coil domain autophagy adaptor 1 involved_in ISO (PMID:26468287) ParkinsonsUK-UCL PMID:26468287 NCBI chrNW_004955420:26,019,621...26,076,846
Ensembl chrNW_004955420:26,019,514...26,074,492
JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:16888103)
(MGI:3656111|PMID:16888103)
UniProt PMID:16888103 MGI:3656111 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit involved_in ISO (PMID:28195531) HGNC PMID:28195531 NCBI chrNW_004955478:11,002,174...11,015,123
Ensembl chrNW_004955478:11,002,174...11,015,123
JBrowse link
positive regulation of lipophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in ISO (PMID:23708524) GO_Central PMID:23708524 NCBI chrNW_004955415:5,515,157...5,517,198
Ensembl chrNW_004955415:5,515,697...5,516,980
JBrowse link
G Htt huntingtin involved_in ISO (PMID:25686248) ParkinsonsUK-UCL PMID:25686248 NCBI chrNW_004955514:1,906,189...2,042,357
Ensembl chrNW_004955514:1,906,502...2,038,889
JBrowse link
G Sesn2 sestrin 2 acts_upstream_of_or_within ISO (MGI:5444071|PMID:22958918) MGI PMID:22958918 MGI:5444071 NCBI chrNW_004955452:7,392,644...7,417,204
Ensembl chrNW_004955452:7,393,007...7,417,304
JBrowse link
G Sptlc1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within ISO (PMID:25332431) MGI PMID:25332431 NCBI chrNW_004955515:57,711...161,012
Ensembl chrNW_004955515:57,711...161,611
JBrowse link
G Sptlc2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within ISO (PMID:25332431) MGI PMID:25332431 NCBI chrNW_004955438:1,385,431...1,491,534
Ensembl chrNW_004955438:1,385,431...1,491,578
JBrowse link
positive regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2 interacting protein 3 acts_upstream_of_or_within ISO (PMID:19273585) MGI PMID:19273585 NCBI chrNW_004955477:9,621,812...9,630,406
Ensembl chrNW_004955477:9,621,812...9,638,099
JBrowse link
G Bnip3l BCL2 interacting protein 3 like acts_upstream_of_or_within ISO (PMID:19273585) MGI PMID:19273585 NCBI chrNW_004955403:49,122,408...49,144,162
Ensembl chrNW_004955403:49,122,408...49,144,998
JBrowse link
G C9orf72 C9orf72-SMCR8 complex subunit involved_in ISO (PMID:27103069), (PMID:27334615) HGNC PMID:27103069 PMID:27334615 NCBI chrNW_004955472:7,299,092...7,337,591
Ensembl chrNW_004955472:7,310,788...7,337,735
JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO (PMID:23798385) MGI PMID:23798385 NCBI chrNW_004955405:28,335,493...28,371,912
Ensembl chrNW_004955405:28,332,545...28,372,323
JBrowse link
G Epm2a EPM2A glucan phosphatase, laforin acts_upstream_of_or_within ISO (MGI:4457987|PMID:20453062)
(PMID:20453062)
MGI PMID:20453062 MGI:4457987 NCBI chrNW_004955436:14,925,452...14,982,357
Ensembl chrNW_004955436:14,926,123...14,983,180
JBrowse link
G Gnai3 G protein subunit alpha i3 involved_in ISO (PMID:12642577) UniProt PMID:12642577 NCBI chrNW_004955435:12,965,006...13,005,614
Ensembl chrNW_004955435:12,965,006...13,005,614
JBrowse link
G Gpsm1 G protein signaling modulator 1 involved_in ISO (PMID:12642577) UniProt PMID:12642577 NCBI chrNW_004955513:4,363,534...4,387,356
Ensembl chrNW_004955513:4,361,139...4,387,356
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within ISO (MGI:3847365|PMID:19273585) MGI PMID:19273585 MGI:3847365 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
JBrowse link
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within ISO (MGI:5430482|PMID:20705711) MGI PMID:20705711 MGI:5430482 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (MGI:5819337|PMID:23778976) ParkinsonsUK-UCL PMID:23778976 MGI:5819337 NCBI chrNW_004955580:1,053,823...1,069,802
Ensembl chrNW_004955580:1,053,823...1,069,802
JBrowse link
G Il4 interleukin 4 involved_in ISO (MGI:5702366|PMID:26416964) UniProt PMID:26416964 MGI:5702366 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Kdr kinase insert domain receptor acts_upstream_of_or_within ISO (PMID:23798385) MGI PMID:23798385 NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583
JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chrNW_004955408:9,002,443...9,080,938
Ensembl chrNW_004955408:9,002,458...9,080,938
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (MGI:5819337|PMID:23778976) ParkinsonsUK-UCL PMID:23778976 MGI:5819337 NCBI chrNW_004955411:17,177,335...17,229,957
Ensembl chrNW_004955411:17,177,335...17,229,957
JBrowse link
G Pafah1b2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 involved_in ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chrNW_004955412:18,471,621...18,494,082
Ensembl chrNW_004955412:18,474,199...18,494,082
JBrowse link
G Pim2 Pim-2 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:4361989|PMID:17476689) MGI PMID:17476689 MGI:4361989 NCBI chrNW_004955543:444,314...449,201
Ensembl chrNW_004955543:444,314...449,201
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:20871098) ParkinsonsUK-UCL PMID:20871098 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125
JBrowse link
G Rab12 RAB12, member RAS oncogene family involved_in ISO (MGI:5574288|PMID:23357852) UniProt PMID:23357852 MGI:5574288 NCBI chrNW_004955402:3,102,709...3,109,701
Ensembl chrNW_004955402:3,103,708...3,110,701
JBrowse link
G Rufy4 RUN and FYVE domain containing 4 involved_in ISO (PMID:26416964) UniProt PMID:26416964 NCBI chrNW_004955453:15,243,125...15,259,086
Ensembl chrNW_004955453:15,242,954...15,257,976
JBrowse link
G Scoc short coiled-coil protein involved_in ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chrNW_004955428:3,404,372...3,435,653
Ensembl chrNW_004955428:3,404,326...3,435,759
JBrowse link
G Sesn2 sestrin 2 involved_in ISO (PMID:23274085) UniProt PMID:23274085 NCBI chrNW_004955452:7,392,644...7,417,204
Ensembl chrNW_004955452:7,393,007...7,417,304
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:18296641)
(MGI:3776699|PMID:18296641), (MGI:4940431|PMID:21189328)
UniProt PMID:18296641 PMID:21189328 MGI:3776699 MGI:4940431 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:30568238), (PMID:30842662)
(MGI:6305034|PMID:30568238)
UniProt PMID:30568238 PMID:30842662 MGI:6305034 NCBI chrNW_004955418:1,091,022...1,097,064
Ensembl chrNW_004955418:1,083,613...1,100,448
JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit involved_in ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chrNW_004955468:95,997...123,005
Ensembl chrNW_004955468:95,181...123,147
JBrowse link
G Tbk1 TANK binding kinase 1 involved_in ISO (PMID:27103069) HGNC PMID:27103069 NCBI chrNW_004955458:11,210,120...11,263,632
Ensembl chrNW_004955458:11,211,398...11,263,867
JBrowse link
G Trim13 tripartite motif containing 13 involved_in ISO (PMID:22178386) UniProt PMID:22178386 NCBI chrNW_004955431:3,324,331...3,395,724
Ensembl chrNW_004955431:3,324,331...3,395,724
JBrowse link
G Tsc1 TSC complex subunit 1 ISO RGD PMID:23435171 RGD:10448950 NCBI chrNW_004955513:2,197,037...2,244,992
Ensembl chrNW_004955513:2,197,037...2,244,992
JBrowse link
G Tsc2 TSC complex subunit 2 involved_in
acts_upstream_of_or_within
ISO (PMID:23778976)
(MGI:5819337|PMID:23778976)
(MGI:4457987|PMID:20453062)
ParkinsonsUK-UCL
MGI
PMID:20453062 PMID:23778976 MGI:4457987 MGI:5819337 NCBI chrNW_004955442:15,178,356...15,216,978
Ensembl chrNW_004955442:15,178,487...15,216,362
JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chrNW_004955462:2,358,842...2,435,644
Ensembl chrNW_004955462:2,358,842...2,435,628
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO (PMID:30217973) UniProt PMID:30217973 NCBI chrNW_004955422:1,455,392...1,644,368
Ensembl chrNW_004955422:1,455,380...1,644,452
JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:22922758) UniProt PMID:22922758 NCBI chrNW_004955524:2,788,672...2,798,068
Ensembl chrNW_004955524:2,788,653...2,796,370
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:28608965 RGD:13432560 NCBI chrNW_004955439:18,664,230...19,953,358
Ensembl chrNW_004955439:18,664,379...19,951,152
JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in ISO (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chrNW_004955403:23,878,329...23,882,322
Ensembl chrNW_004955403:23,878,329...23,882,322
JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISO (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chrNW_004955534:497,518...500,309
Ensembl chrNW_004955534:496,933...510,934
JBrowse link
G Vdac1 voltage dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chrNW_004955408:5,260,444...5,275,972
Ensembl chrNW_004955408:5,260,353...5,275,990
JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D involved_in ISO (PMID:29307555) UniProt PMID:29307555 NCBI chrNW_004955486:1,515,630...1,772,107
Ensembl chrNW_004955486:1,513,712...1,767,956
JBrowse link
positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vdac1 voltage dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chrNW_004955408:5,260,444...5,275,972
Ensembl chrNW_004955408:5,260,353...5,275,990
JBrowse link
positive regulation of xenophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO (PMID:23245322) GO_Central PMID:23245322 NCBI chrNW_004955419:1,121,127...1,154,356
Ensembl chrNW_004955419:1,121,127...1,154,356
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chrNW_004955493:6,870,699...6,876,836
Ensembl chrNW_004955493:6,869,668...6,879,152
JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chrNW_004955410:31,681,191...31,725,173
Ensembl chrNW_004955410:31,681,077...31,725,173
JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710
JBrowse link
G Optn optineurin involved_in ISO (PMID:21617041) ParkinsonsUK-UCL PMID:21617041 NCBI chrNW_004955462:1,098,118...1,150,291
Ensembl chrNW_004955462:1,107,510...1,151,269
JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228
JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO (PMID:28481331) UniProt PMID:28481331 NCBI chrNW_004955409:36,240,008...36,252,166 JBrowse link
G Tbk1 TANK binding kinase 1 involved_in ISO (MGI:5645201|PMID:21617041) ParkinsonsUK-UCL PMID:21617041 MGI:5645201 NCBI chrNW_004955458:11,210,120...11,263,632
Ensembl chrNW_004955458:11,211,398...11,263,867
JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
JBrowse link
regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg12 autophagy related 12 involved_in ISO (PMID:22342342) ComplexPortal PMID:22342342 NCBI chrNW_004955408:35,607,541...35,620,878
Ensembl chrNW_004955408:35,607,541...35,620,878
JBrowse link
G Atg5 autophagy related 5 involved_in ISO (PMID:22342342) ComplexPortal PMID:22342342 NCBI chrNW_004955411:31,501,191...31,646,407
Ensembl chrNW_004955411:31,522,420...31,646,827
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:5698740 NCBI chrNW_004955493:6,696,520...6,707,849
Ensembl chrNW_004955493:6,696,241...6,707,849
JBrowse link
G Tbc1d25 TBC1 domain family member 25 involved_in ISO (PMID:21383079) UniProt PMID:21383079 NCBI chrNW_004955543:127,314...154,235
Ensembl chrNW_004955543:127,162...154,235
JBrowse link
G Tecpr1 tectonin beta-propeller repeat containing 1 involved_in ISO (PMID:22342342) ComplexPortal PMID:22342342 NCBI chrNW_004955460:14,106,711...14,137,983
Ensembl chrNW_004955460:14,106,711...14,138,033
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12199
    cellular process 11340
      process utilizing autophagic mechanism 398
        autophagy 398
          macroautophagy 227
            regulation of macroautophagy 111
              negative regulation of macroautophagy + 31
              positive regulation of macroautophagy + 72
              regulation of aggrephagy + 3
              regulation of autophagosome maturation + 15
              regulation of lipophagy + 5
              regulation of mitophagy + 14
              regulation of reticulophagy + 0
              regulation of xenophagy + 9
Path 2
Term Annotations click to browse term
  biological_process 12199
    biological regulation 8982
      regulation of biological process 8510
        regulation of cellular process 8024
          regulation of cellular metabolic process 4205
            regulation of cellular catabolic process 637
              regulation of autophagy 251
                regulation of macroautophagy 111
                  negative regulation of macroautophagy + 31
                  positive regulation of macroautophagy + 72
                  regulation of aggrephagy + 3
                  regulation of autophagosome maturation + 15
                  regulation of lipophagy + 5
                  regulation of mitophagy + 14
                  regulation of reticulophagy + 0
                  regulation of xenophagy + 9
paths to the root