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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of macroautophagy
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Accession:GO:0016241 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of macroautophagy.
Synonyms:exact_synonym: regulation of starvation-induced autophagy


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regulation of macroautophagy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07001519.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:49,290,112...49,844,547 JBrowse link
G Atp13a2 ATPase cation transporting 13A2 ISO (PMID:22198378) RGD PMID:22198378 NCBI chr 5:159,512,208...159,531,631
Ensembl chr 5:159,512,285...159,531,637
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 ISO
IEA
(PMID:22982048)
GO_REF:0000107
RGD
Ensembl
PMID:22982048 GO_REF:0000107 NCBI chr10:88,914,264...88,967,736
Ensembl chr10:88,914,276...88,967,748
JBrowse link
G Hdac6 histone deacetylase 6 ISO (PMID:16192271) RGD PMID:16192271 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 IEA
ISO
ISS
GO_REF:0000107
(MGI:5619439|PMID:23332761)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23332761 GO_REF:0000024, GO_REF:0000107, MGI:5619439 NCBI chr 5:124,568,845...124,642,569
Ensembl chr 5:124,574,079...124,642,569
JBrowse link
G Ubqln1 ubiquilin 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:6,840,441...6,878,842
Ensembl chr17:6,840,463...6,878,844
JBrowse link
G Ubqln2 ubiquilin 2 ISO
IBA
(PMID:20529957)
PMID:21873635
RGD PMID:20529957, PMID:21873635 RGD:13792537 NCBI chr  X:18,723,313...18,726,732
Ensembl chr  X:18,723,341...18,726,732
JBrowse link
negative regulation of autophagosome assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 ISO MGI:2683833 (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Chmp4b charged multivesicular body protein 4B ISO (PMID:21975012) RGD PMID:21975012 NCBI chr 3:150,188,275...150,227,453
Ensembl chr 3:150,188,455...150,227,405
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO (MGI:5543871|PMID:23918802) RGD PMID:23918802 MGI:5543871 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 ISO
ISS
(PMID:25495476)
GO_REF:0000024
RGD
GO_Central
PMID:25495476 GO_REF:0000024 NCBI chr 8:39,305,128...39,350,270
Ensembl chr 8:39,305,128...39,350,270
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 ISO
ISS
IEA
(PMID:25495476)
GO_REF:0000024
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:25495476 GO_REF:0000024, GO_REF:0000107 NCBI chr 6:963,903...1,003,955
Ensembl chr 6:963,907...1,004,001
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO
IBA
(PMID:23916833)
PMID:21873635
RGD PMID:23916833, PMID:21873635 RGD:13792537 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Mtm1 myotubularin 1 IBA
ISO
PMID:21873635
MGI:2450997 (MGI:5510937|PMID:23695157)
RGD PMID:23695157, PMID:21873635 MGI:5510937, RGD:13792537 NCBI chr 6:18,821,821...18,840,449
Ensembl chr 6:18,821,815...18,839,409
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator ISS
ISO
GO_REF:0000024
(PMID:20181828)
UniProt
RGD
PMID:20181828 GO_REF:0000024 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Phf23 PHD finger protein 23 ISO
IBA
ISS
(PMID:25484098)
PMID:21873635
GO_REF:0000024
RGD
GO_Central
PMID:25484098, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:56,605,078...56,609,236
Ensembl chr10:56,605,140...56,609,233
JBrowse link
G Pink1 PTEN induced kinase 1 ISO (PMID:19279012) RGD PMID:19279012 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Scfd1 sec1 family domain containing 1 ISO (PMID:21242315) RGD PMID:21242315 NCBI chr 6:72,124,408...72,202,703
Ensembl chr 6:72,124,417...72,202,713
JBrowse link
G Sec22b SEC22 homolog B, vesicle trafficking protein ISO (PMID:21242315) RGD PMID:21242315 NCBI chr 2:200,076,079...200,096,861
Ensembl chr 2:200,076,054...200,098,076
JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit ISO (PMID:28195531) RGD PMID:28195531 NCBI chr10:47,019,326...47,026,465
Ensembl chr10:47,018,974...47,026,465
JBrowse link
G Tmem39a transmembrane protein 39a ISO
IBA
ISS
(PMID:31806350)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:31806350, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:64,723,181...64,752,514
Ensembl chr11:64,723,186...64,752,544
JBrowse link
negative regulation of autophagosome maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A ISO (PMID:28223137) RGD PMID:28223137 NCBI chr10:5,002,196...5,196,914
Ensembl chr10:5,009,826...5,196,892
JBrowse link
G Phf23 PHD finger protein 23 ISO
IBA
ISS
(PMID:25484098)
PMID:21873635
GO_REF:0000024
RGD
GO_Central
PMID:25484098, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:56,605,078...56,609,236
Ensembl chr10:56,605,140...56,609,233
JBrowse link
G Rubcn rubicon autophagy regulator ISO
IBA
(PMID:21062745)
PMID:21873635
RGD PMID:21062745, PMID:21873635 RGD:13792537 NCBI chr11:71,150,506...71,199,254
Ensembl chr11:71,151,132...71,197,035
JBrowse link
G Tmem39a transmembrane protein 39a ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:31806350)
UniProt
RGD
PMID:31806350, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:64,723,181...64,752,514
Ensembl chr11:64,723,186...64,752,544
JBrowse link
G Ubqln4 ubiquilin 4 ISO (PMID:23459205) RGD PMID:23459205 NCBI chr 2:187,915,701...187,931,035
Ensembl chr 2:187,915,751...187,931,035
JBrowse link
negative regulation of macroautophagy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 ISO MGI:2429784 (MGI:5430482|PMID:20705711) RGD PMID:20705711 MGI:5430482 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (PMID:19640926) RGD PMID:19640926 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 ISO (PMID:22354037) RGD PMID:22354037 NCBI chr16:22,250,452...22,306,667
Ensembl chr16:22,250,470...22,306,662
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO
IBA
(PMID:25327288)
(MGI:3690270|PMID:16714284), (MGI:5563734|PMID:23274896)
PMID:21873635
RGD PMID:16714284, PMID:23274896, PMID:25327288, PMID:21873635 MGI:3690270, MGI:5563734, RGD:13792537 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 ISO MGI:1857409|MGI:1891828 (MGI:3723543|PMID:17468177) RGD PMID:17468177 MGI:3723543 NCBI chr18:3,616,878...3,662,656
Ensembl chr18:3,616,878...3,662,683
JBrowse link
G Nrbp2 nuclear receptor binding protein 2 ISO (PMID:22354037) RGD PMID:22354037 NCBI chr 7:117,145,106...117,151,694
Ensembl chr 7:117,145,961...117,151,694
JBrowse link
G Pink1 PTEN induced kinase 1 ISO (PMID:19279012) RGD PMID:19279012 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Poldip2 DNA polymerase delta interacting protein 2 ISO MGI:4044390 (MGI:5588624|PMID:24797518) RGD PMID:24797518 MGI:5588624 NCBI chr10:65,781,994...65,790,833
Ensembl chr10:65,780,494...65,790,272
JBrowse link
G Qsox1 quiescin sulfhydryl oxidase 1 ISO (PMID:24475161) RGD PMID:24475161 NCBI chr13:73,423,396...73,460,890
Ensembl chr13:73,423,397...73,460,935
JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit ISO (PMID:28195531) RGD PMID:28195531 NCBI chr10:47,019,326...47,026,465
Ensembl chr10:47,018,974...47,026,465
JBrowse link
G Tsc1 TSC complex subunit 1 IMP PMID:23435171 ParkinsonsUK-UCL PMID:23435171 RGD:10448950 NCBI chr 3:7,219,955...7,269,063
Ensembl chr 3:7,237,192...7,265,145
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:24599401 RGD:11568679 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Usp36 ubiquitin specific peptidase 36 ISO (PMID:22622177) RGD PMID:22622177 NCBI chr10:107,292,828...107,324,355
Ensembl chr10:107,292,828...107,324,355
JBrowse link
negative regulation of macroautophagy by TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A ISO (PMID:28223137) RGD PMID:28223137 NCBI chr10:5,002,196...5,196,914
Ensembl chr10:5,009,826...5,196,892
JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A ISO MGI:5648633 (MGI:5603233|PMID:24949970) RGD PMID:24949970 MGI:5603233 NCBI chr10:5,002,196...5,196,914
Ensembl chr10:5,009,826...5,196,892
JBrowse link
G Rnf41 ring finger protein 41 ISO MGI:1921624 (MGI:5603233|PMID:24949970) RGD PMID:24949970 MGI:5603233 NCBI chr 7:2,827,242...2,854,230
Ensembl chr 7:2,827,247...2,852,681
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase ISO MGI:5319187 (MGI:5319065|PMID:22044588) RGD PMID:22044588 MGI:5319065 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link
G Tp53 tumor protein p53 ISO MGI:1857263 (MGI:5319065|PMID:22044588) RGD PMID:22044588 MGI:5319065 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Usp30 ubiquitin specific peptidase 30 IMP RGD PMID:24896179 RGD:13208875 NCBI chr12:48,262,663...48,316,580
Ensembl chr12:48,262,658...48,316,722
JBrowse link
negative regulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra2 HtrA serine peptidase 2 ISO (MGI:5581539|PMID:24709290) RGD PMID:24709290 MGI:5581539 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps13c vacuolar protein sorting 13 homolog C ISO
ISS
(PMID:26942284)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:26942284 GO_REF:0000024 NCBI chr 8:73,682,814...73,843,290
Ensembl chr 8:73,682,887...73,842,928
JBrowse link
parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 ISO UniProtKB:Q9JK66|UniProtKB:Q9Z2V5 (PMID:20457763) RGD PMID:20457763 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Mfn2 mitofusin 2 ISO (MGI:5498413|PMID:23620051) RGD PMID:23620051 MGI:5498413 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Optn optineurin IEA
ISO
GO_REF:0000107
(PMID:25294927)
Ensembl
RGD
PMID:25294927 GO_REF:0000107 NCBI chr17:77,167,700...77,218,374
Ensembl chr17:77,167,740...77,218,389
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO (PMID:19029340) RGD PMID:19029340 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO (MGI:5298125|PMID:22020285) RGD PMID:22020285 MGI:5298125 NCBI chr12:11,433,815...11,526,465
Ensembl chr12:11,407,213...11,526,465
JBrowse link
positive regulation of aggrephagy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag3 BAG cochaperone 3 ISO (PMID:18006506) RGD PMID:18006506 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 ISO (PMID:18006506) RGD PMID:18006506 NCBI chr12:45,905,371...45,920,014
Ensembl chr12:45,905,371...45,920,013
JBrowse link
G Htt huntingtin IEA
ISO
GO_REF:0000107
(PMID:25686248)
Ensembl
RGD
PMID:25686248 GO_REF:0000107 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
positive regulation of autophagosome assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 IMP RGD PMID:25561470 RGD:11561937 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Elapor1 endosome-lysosome associated apoptosis and autophagy regulator 1 ISO
IEA
(PMID:21072319)
GO_REF:0000107
RGD
Ensembl
PMID:21072319 GO_REF:0000107 NCBI chr 2:211,243,398...211,323,283
Ensembl chr 2:211,246,068...211,322,719
JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 ISO (PMID:25484098) RGD PMID:25484098 NCBI chr 3:11,970,401...12,009,463
Ensembl chr 3:11,972,813...12,007,570
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha ISO (PMID:25578879) RGD PMID:25578879 NCBI chr17:85,533,056...85,748,843 JBrowse link
G Pip4k2b phosphatidylinositol-5-phosphate 4-kinase type 2 beta ISO (PMID:25578879) RGD PMID:25578879 NCBI chr10:85,655,223...85,684,138
Ensembl chr10:85,658,324...85,684,138
JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase type 2 gamma ISO
IEA
(PMID:25578879)
GO_REF:0000107
RGD
Ensembl
PMID:25578879 GO_REF:0000107 NCBI chr 7:70,483,948...70,498,995
Ensembl chr 7:70,483,942...70,498,995
JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 ISO
ISS
IEA
(PMID:25495476)
GO_REF:0000024
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:25495476 GO_REF:0000024, GO_REF:0000107 NCBI chr13:44,578,208...44,649,876
Ensembl chr13:44,615,553...44,648,620
JBrowse link
G Rab3gap2 RAB3 GTPase activating non-catalytic protein subunit 2 ISO
ISS
IEA
(PMID:25495476)
GO_REF:0000024
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:25495476 GO_REF:0000024, GO_REF:0000107 NCBI chr13:103,157,806...103,229,010
Ensembl chr13:103,157,806...103,228,423
JBrowse link
G Ralb RAS like proto-oncogene B IEA
ISO
GO_REF:0000107
(PMID:24056301)
Ensembl
RGD
PMID:24056301 GO_REF:0000107 NCBI chr13:35,494,716...35,531,503
Ensembl chr13:35,494,721...35,511,020
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 IEA
ISO
GO_REF:0000107
(MGI:5634888|PMID:21068542)
(PMID:21068542)
Ensembl
RGD
PMID:21068542 GO_REF:0000107, MGI:5634888 NCBI chr 2:250,709,812...250,744,216
Ensembl chr 2:250,709,439...250,744,196
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 IMP RGD PMID:23448468 RGD:13208863 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
positive regulation of autophagosome maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07025818.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr16:51,786,459...51,787,151 JBrowse link
G Adrb2 adrenoceptor beta 2 ISO
ISS
IEA
(PMID:23708524)
GO_REF:0000024
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:23708524 GO_REF:0000024, GO_REF:0000107 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Calcoco2 calcium binding and coiled-coil domain 2 ISO (PMID:25771791) RGD PMID:25771791 NCBI chr10:83,935,087...83,963,750 JBrowse link
G Clec16a C-type lectin domain containing 16A ISO MGI:5648633 (MGI:5603233|PMID:24949970) RGD PMID:24949970 MGI:5603233 NCBI chr10:5,002,196...5,196,914
Ensembl chr10:5,009,826...5,196,892
JBrowse link
G Fyco1 FYVE and coiled-coil domain autophagy adaptor 1 ISO
IBA
(PMID:26468287)
PMID:21873635
RGD PMID:26468287, PMID:21873635 RGD:13792537 NCBI chr 8:132,844,042...132,910,905
Ensembl chr 8:132,844,043...132,911,193
JBrowse link
G Irgm immunity-related GTPase M ISO (PMID:16888103)
(MGI:3656111|PMID:16888103)
RGD PMID:16888103 MGI:3656111 NCBI chr10:34,213,885...34,221,968
Ensembl chr10:34,213,936...34,221,928
JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit ISO (PMID:28195531) RGD PMID:28195531 NCBI chr10:47,019,326...47,026,465
Ensembl chr10:47,018,974...47,026,465
JBrowse link
positive regulation of lipophagy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 ISO
ISS
IEA
(PMID:23708524)
GO_REF:0000024
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:23708524 GO_REF:0000024, GO_REF:0000107 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Htt huntingtin IEA
ISO
GO_REF:0000107
(PMID:25686248)
Ensembl
RGD
PMID:25686248 GO_REF:0000107 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Sesn2 sestrin 2 ISO MGI:3587950 (MGI:5444071|PMID:22958918) RGD PMID:22958918 MGI:5444071 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 ISO (PMID:25332431) RGD PMID:25332431 NCBI chr17:11,856,525...11,895,566
Ensembl chr17:11,856,525...11,895,566
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 ISO (PMID:25332431) RGD PMID:25332431 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link
positive regulation of macroautophagy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2 interacting protein 3 ISO UniProtKB:O60238 (PMID:19273585) RGD PMID:19273585 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bnip3l BCL2 interacting protein 3 like ISO UniProtKB:Q12983 (PMID:19273585) RGD PMID:19273585 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Dcn decorin ISO UniProtKB:P35968 (PMID:23798385) RGD PMID:23798385 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Epm2a EPM2A glucan phosphatase, laforin ISO (PMID:20453062)
MGI:102548|MGI:2182627 (MGI:4457987|PMID:20453062)
RGD PMID:20453062 MGI:4457987 NCBI chr 1:5,448,958...5,571,512
Ensembl chr 1:5,448,958...5,571,512
JBrowse link
G Gnai3 G protein subunit alpha i3 ISO (PMID:12642577) RGD PMID:12642577 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749
JBrowse link
G Gpsm1 G-protein signaling modulator 1 ISO (PMID:12642577) RGD PMID:12642577 NCBI chr 3:3,767,394...3,794,360
Ensembl chr 3:3,767,394...3,794,359
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEA
ISO
GO_REF:0000107
MGI:2386679 (MGI:3847365|PMID:19273585)
Ensembl
RGD
PMID:19273585 GO_REF:0000107, MGI:3847365 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 ISO MGI:2429784 (MGI:5430482|PMID:20705711) RGD PMID:20705711 MGI:5430482 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO (MGI:5819337|PMID:23778976) RGD PMID:23778976 MGI:5819337 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Il4 interleukin 4 ISS
ISO
IBA
GO_REF:0000024
(MGI:5702366|PMID:26416964)
PMID:21873635
UniProt
RGD
PMID:26416964, PMID:21873635 GO_REF:0000024, MGI:5702366, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Kdr kinase insert domain receptor ISO
IEA
UniProtKB:P07585 (PMID:23798385)
GO_REF:0000107
RGD
Ensembl
PMID:23798385 GO_REF:0000107 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator ISO (PMID:22354037) RGD PMID:22354037 NCBI chr10:43,435,738...43,501,186
Ensembl chr10:43,446,526...43,498,066
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO (MGI:5819337|PMID:23778976) RGD PMID:23778976 MGI:5819337 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416
JBrowse link
G Pafah1b2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 ISO (PMID:22354037) RGD PMID:22354037 NCBI chr 8:50,256,969...50,310,043
Ensembl chr 8:50,259,248...50,277,797
JBrowse link
G Pim2 Pim-2 proto-oncogene, serine/threonine kinase ISO (MGI:4361989|PMID:17476689) RGD PMID:17476689 MGI:4361989 NCBI chr  X:15,462,621...15,467,890
Ensembl chr  X:15,462,016...15,467,875
JBrowse link
G Pink1 PTEN induced kinase 1 ISO (PMID:20871098) RGD PMID:20871098 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Rab12 RAB12, member RAS oncogene family ISO (MGI:5574288|PMID:23357852) RGD PMID:23357852 MGI:5574288 NCBI chr 9:114,683,985...114,709,613
Ensembl chr 9:114,684,039...114,709,546
JBrowse link
G RGD1359108 similar to RIKEN cDNA 3110043O21 IEA
ISO
ISS
GO_REF:0000107
UniProtKB:Q96DA2 (PMID:27103069), (PMID:27334615)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:27103069, PMID:27334615 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:50,666,444...50,691,523
Ensembl chr 5:50,668,040...50,684,409
JBrowse link
G Rufy4 RUN and FYVE domain containing 4 ISO
IBA
(PMID:26416964)
PMID:21873635
RGD PMID:26416964, PMID:21873635 RGD:13792537 NCBI chr 9:81,401,080...81,422,016
Ensembl chr 9:81,402,124...81,421,990
JBrowse link
G Scoc short coiled-coil protein ISO
ISS
(PMID:22354037)
GO_REF:0000024
RGD
GO_Central
PMID:22354037 GO_REF:0000024 NCBI chr19:24,584,435...24,614,167
Ensembl chr19:24,584,455...24,614,019
JBrowse link
G Sesn1 sestrin 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:46,667,116...46,758,306
Ensembl chr20:46,667,121...46,758,305
JBrowse link
G Sesn2 sestrin 2 ISO
IBA
(PMID:23274085)
PMID:21873635
RGD PMID:23274085, PMID:21873635 RGD:13792537 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sesn3 sestrin 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:12,823,060...12,878,749
Ensembl chr 8:12,823,155...12,872,705
JBrowse link
G Sirt1 sirtuin 1 ISO
IEA
(PMID:18296641)
(MGI:3776699|PMID:18296641), (MGI:4940431|PMID:21189328)
GO_REF:0000107
RGD
Ensembl
PMID:18296641, PMID:21189328 GO_REF:0000107, MGI:3776699, MGI:4940431 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 ISS
ISO
IBA
GO_REF:0000024
(MGI:6305034|PMID:30568238)
PMID:21873635
(PMID:30568238), (PMID:30842662)
UniProt
RGD
PMID:30568238, PMID:30842662, PMID:21873635 GO_REF:0000024, MGI:6305034, RGD:13792537 NCBI chr18:28,529,537...28,535,828
Ensembl chr18:28,529,576...28,535,828
JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit ISO (PMID:22354037) RGD PMID:22354037 NCBI chr 1:85,437,780...85,466,854
Ensembl chr 1:85,437,780...85,466,854
JBrowse link
G Tbk1 TANK-binding kinase 1 ISO (PMID:27103069) RGD PMID:27103069 NCBI chr 7:63,655,247...63,687,978
Ensembl chr 7:63,655,247...63,687,978
JBrowse link
G Trim13 tripartite motif-containing 13 ISO
IBA
(PMID:22178386)
PMID:21873635
RGD PMID:22178386, PMID:21873635 RGD:13792537 NCBI chr15:41,897,191...41,936,545
Ensembl chr15:41,927,241...41,935,718
JBrowse link
G Tsc1 TSC complex subunit 1 IDA RGD PMID:23435171 RGD:10448950 NCBI chr 3:7,219,955...7,269,063
Ensembl chr 3:7,237,192...7,265,145
JBrowse link
G Tsc2 TSC complex subunit 2 ISO
IEA
UniProtKB:Q61037 (PMID:23778976)
(MGI:4457987|PMID:20453062), (MGI:5819337|PMID:23778976)
GO_REF:0000107
RGD
Ensembl
PMID:20453062, PMID:23778976 GO_REF:0000107, MGI:4457987, MGI:5819337 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Wac WW domain containing adaptor with coiled-coil ISO (PMID:22354037) RGD PMID:22354037 NCBI chr17:60,887,606...60,946,630
Ensembl chr17:60,888,017...60,946,426
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:28608965 RGD:13432560 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Vdac1 voltage-dependent anion channel 1 ISO (PMID:32047033) RGD PMID:32047033 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D ISO (PMID:29307555) RGD PMID:29307555 NCBI chr 5:162,891,451...163,119,239
Ensembl chr 5:162,891,451...163,119,239
JBrowse link
positive regulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc37 cell division cycle 37, HSP90 cochaperone IEA
ISO
GO_REF:0000107
(MGI:5607224|PMID:21855797)
Ensembl
RGD
PMID:21855797 GO_REF:0000107, MGI:5607224 NCBI chr 8:22,160,922...22,173,797
Ensembl chr 8:22,154,067...22,173,804
JBrowse link
G Hdac6 histone deacetylase 6 ISO UniProtKB:Q9JK66 (MGI:5616310|PMID:20457763) RGD PMID:20457763 MGI:5616310 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 IEA
ISO
GO_REF:0000107
(PMID:30217973)
Ensembl
RGD
PMID:30217973 GO_REF:0000107 NCBI chr  X:21,474,627...21,603,348
Ensembl chr  X:21,499,934...21,598,876
JBrowse link
G Pink1 PTEN induced kinase 1 ISO (PMID:20871098) RGD PMID:20871098 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO (PMID:20457763), (PMID:20871098), (PMID:23212910) RGD PMID:20457763, PMID:20871098, PMID:23212910 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 ISO (PMID:24270810) RGD PMID:24270810 NCBI chr 4:7,835,949...7,842,790
Ensembl chr 4:7,835,949...7,842,789
JBrowse link
positive regulation of xenophagy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 ISO (PMID:23245322) RGD PMID:23245322 NCBI chr 3:11,970,401...12,009,463
Ensembl chr 3:11,972,813...12,007,570
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO MGI:1346858 (MGI:5299952|PMID:22033934) RGD PMID:22033934 MGI:5299952 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 ISO MGI:2674231 (MGI:5299952|PMID:22033934) RGD PMID:22033934 MGI:5299952 NCBI chr 4:85,123,965...85,175,206
Ensembl chr 4:85,123,960...85,174,951
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO MGI:3529594 (MGI:5299952|PMID:22033934) RGD PMID:22033934 MGI:5299952 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Optn optineurin ISO
IEA
(PMID:21617041)
GO_REF:0000107
RGD
Ensembl
PMID:21617041 GO_REF:0000107 NCBI chr17:77,167,700...77,218,374
Ensembl chr17:77,167,740...77,218,389
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 ISO MGI:2660793 (MGI:5299952|PMID:22033934) RGD PMID:22033934 MGI:5299952 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735
JBrowse link
G Tbk1 TANK-binding kinase 1 ISO (MGI:5645201|PMID:21617041) RGD PMID:21617041 MGI:5645201 NCBI chr 7:63,655,247...63,687,978
Ensembl chr 7:63,655,247...63,687,978
JBrowse link
G Tlr2 toll-like receptor 2 ISO MGI:2674036 (MGI:5299952|PMID:22033934) RGD PMID:22033934 MGI:5299952 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
regulation of autophagosome maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:5,002,196...5,196,914
Ensembl chr10:5,009,826...5,196,892
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:5698740|PMID:26450516) RGD PMID:26450516 MGI:5698740 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Tbc1d25 TBC1 domain family, member 25 ISO
IBA
(PMID:21383079)
PMID:21873635
RGD PMID:21383079, PMID:21873635 RGD:13792537 NCBI chr  X:15,064,733...15,088,579
Ensembl chr  X:15,064,594...15,088,589
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      process utilizing autophagic mechanism 467
        autophagy 467
          macroautophagy 226
            regulation of macroautophagy 103
              negative regulation of macroautophagy + 32
              positive regulation of macroautophagy + 70
              regulation of aggrephagy + 3
              regulation of autophagosome maturation + 13
              regulation of lipophagy + 5
              regulation of mitophagy + 18
              regulation of reticulophagy + 0
              regulation of xenophagy + 8
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of cellular process 12556
          regulation of cellular metabolic process 6227
            regulation of cellular catabolic process 760
              regulation of autophagy 291
                regulation of macroautophagy 103
                  negative regulation of macroautophagy + 32
                  positive regulation of macroautophagy + 70
                  regulation of aggrephagy + 3
                  regulation of autophagosome maturation + 13
                  regulation of lipophagy + 5
                  regulation of mitophagy + 18
                  regulation of reticulophagy + 0
                  regulation of xenophagy + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.