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ONTOLOGY REPORT - ANNOTATIONS


Term:inclusion body
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Accession:GO:0016234 term browser browse the term
Definition:A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers.
Synonyms:narrow_synonym: neuronal cytoplasmic inclusion
 related_synonym: cellular inclusion
 xref: NIF_Subcellular:sao120573470;   Wikipedia:Inclusion_bodies


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inclusion body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agl amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase located_in ISO (MGI:3758968|PMID:17908927) MGI PMID:17908927 MGI:3758968 NCBI chrNW_004937224:23,225...32,639 JBrowse link
G Bag5 BAG cochaperone 5 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936621:1,573,237...1,578,257 JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 located_in ISO (PMID:15936278) BHF-UCL PMID:15936278 NCBI chrNW_004936569:1,689,926...1,697,179 JBrowse link
G Gys1 glycogen synthase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:2,978,546...2,995,145 JBrowse link
G Hap1 huntingtin associated protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:16,645,116...16,652,310 JBrowse link
G Hdac6 histone deacetylase 6 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936721:757,500...778,416 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO pseudovacuole RGD PMID:18445155 RGD:5686867 NCBI chrNW_004936476:15,830,459...15,836,994 JBrowse link
G Keap1 kelch like ECH associated protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936659:785,059...793,775 JBrowse link
G LOC101954740 islet amyloid polypeptide located_in ISO (PMID:22944668) UniProt PMID:22944668 NCBI chrNW_004936548:5,463,829...5,469,136 JBrowse link
G LOC101955831 heat shock 70 kDa protein 1 located_in ISO (PMID:15603737) BHF-UCL PMID:15603737 NCBI chrNW_004936727:1,718,952...1,721,691 JBrowse link
G LOC101956126 heat shock 70 kDa protein 1 located_in ISO (PMID:15603737) BHF-UCL PMID:15603737 NCBI chrNW_004936727:1,732,323...1,735,128 JBrowse link
G LOC101959784 prion protein located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:14,104,829...14,118,614 JBrowse link
G LOC101966195 huntingtin located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936477:20,443,101...20,577,167 JBrowse link
G LOC101974150 WD repeat and FYVE domain-containing protein 3 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936738:31,426...150,463 JBrowse link
G Lrrk2 leucine rich repeat kinase 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936607:628,469...761,117 JBrowse link
G Miox myo-inositol oxygenase located_in ISO (PMID:11716759) UniProt PMID:11716759 NCBI chrNW_004936629:355,517...357,678 JBrowse link
G Mt3 metallothionein 3 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:8,864,512...8,866,516 JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 ISO RGD PMID:18986984 RGD:7242199 NCBI chrNW_004936661:2,522,665...2,528,279 JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 ISO RGD PMID:18986984 RGD:7242199 NCBI chrNW_004936541:4,470,210...4,475,233 JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 ISO RGD PMID:18986984 RGD:7242199 NCBI chrNW_004936697:2,122,727...2,143,988 JBrowse link
G Rad50 RAD50 double strand break repair protein ISO Ad5-transformed BRK cells RGD PMID:18212738 RGD:2300253 NCBI chrNW_004936647:2,546,100...2,637,524 JBrowse link
G Snca synuclein alpha located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936685:2,077,017...2,175,298 JBrowse link
G Sncb synuclein beta located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936597:878,270...888,346 JBrowse link
G Sqstm1 sequestosome 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936739:943,080...955,296 JBrowse link
G Zp2 zona pellucida glycoprotein 2 located_in ISO (PMID:12052239) UniProt PMID:12052239 NCBI chrNW_004936501:6,394,838...6,407,512 JBrowse link
aggresome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cabin1 calcineurin binding protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936619:890,474...1,030,914 JBrowse link
G Card14 caspase recruitment domain family member 14 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:4,174,258...4,195,165 JBrowse link
G Clu clusterin ISO RGD PMID:12799419 RGD:1582417 NCBI chrNW_004936675:499,745...513,515 JBrowse link
G Dvl2 dishevelled segment polarity protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:520,299...528,361 JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936577:4,486,617...4,516,379 JBrowse link
G Eef2 eukaryotic translation elongation factor 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:2,259,236...2,267,692 JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 located_in ISO (PMID:16159959) UniProt PMID:16159959 NCBI chrNW_004936522:9,438,929...9,486,781 JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:11,897,998...11,919,153 JBrowse link
G Hdac6 histone deacetylase 6 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936721:757,500...778,416 JBrowse link
G Hoxc9 homeobox C9 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:11,222,120...11,225,455 JBrowse link
G Hoxd3 homeobox D3 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936509:5,654,737...5,659,937 JBrowse link
G Hspb7 heat shock protein family B (small) member 7 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:3,583,999...3,587,316 JBrowse link
G Klf8 Kruppel like factor 8 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936819:633,562...673,365 JBrowse link
G Klhl14 kelch like family member 14 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936682:599,716...697,235 JBrowse link
G LOC101955357 uncharacterized LOC101955357 located_in ISO (MGI:4421086|PMID:19819238) MGI PMID:19819238 MGI:4421086 NCBI chrNW_004936862:405,205...413,920 JBrowse link
G LOC101955831 heat shock 70 kDa protein 1 located_in ISO (PMID:15885686) UniProt PMID:15885686 NCBI chrNW_004936727:1,718,952...1,721,691 JBrowse link
G LOC101956126 heat shock 70 kDa protein 1 located_in ISO (PMID:15885686) UniProt PMID:15885686 NCBI chrNW_004936727:1,732,323...1,735,128 JBrowse link
G LOC101976627 prosaposin located_in ISO (MGI:4819645|PMID:20498017) MGI PMID:20498017 MGI:4819645 NCBI chrNW_004936521:6,975,844...7,009,460 JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936889:231,373...250,985 JBrowse link
G Prdm16 PR/SET domain 16 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936737:400,819...446,768 JBrowse link
G Prkcq protein kinase C theta located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936484:8,048,239...8,166,058 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Psen1 presenilin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936488:2,464,623...2,528,807 JBrowse link
G Rangap1 Ran GTPase activating protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:595,905...626,219 JBrowse link
G Rnf32 ring finger protein 32 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936797:876,305...906,252 JBrowse link
G Sfmbt2 Scm like with four mbt domains 2 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004936484:7,344,144...7,558,341 JBrowse link
G Sqstm1 sequestosome 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936739:943,080...955,296 JBrowse link
G Stradb STE20 related adaptor beta located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936726:709,037...728,696 JBrowse link
G Tdp2 tyrosyl-DNA phosphodiesterase 2 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004948563:494...1,113 JBrowse link
G Trim37 tripartite motif containing 37 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:4,163,871...4,310,016 JBrowse link
G Trim50 tripartite motif containing 50 located_in ISO (MGI:5446594|PMID:22792322) MGI PMID:22792322 MGI:5446594 NCBI chrNW_004936543:2,624,441...2,638,190 JBrowse link
G Trim66 tripartite motif containing 66 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936528:9,358,976...9,410,425 JBrowse link
G Ubd ubiquitin D located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936723:1,218,621...1,221,070 JBrowse link
G Ubqln1 ubiquilin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936828:543,651...588,673 JBrowse link
G Urb2 URB2 ribosome biogenesis homolog located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936484:20,098,210...20,118,808 JBrowse link
G Xrn2 5'-3' exoribonuclease 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936620:4,069,956...4,145,212 JBrowse link
G Zbtb14 zinc finger and BTB domain containing 14 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936779:1,198,469...1,205,671 JBrowse link
G Zdhhc17 zinc finger DHHC-type palmitoyltransferase 17 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936568:4,959,796...5,052,254 JBrowse link
classical Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:7,261,442...7,276,779 JBrowse link
glial cytoplasmic inclusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:7,261,442...7,276,779 JBrowse link
Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:31,822,592...31,947,624 JBrowse link
G Gpx1 glutathione peroxidase 1 colocalizes_with
located_in
ISO
IEA
(PMID:18853169) ParkinsonsUK-UCL
Ensembl
PMID:18853169 GO_REF:0000107 NCBI chrNW_004936529:997,943...999,123 JBrowse link
G Nub1 negative regulator of ubiquitin like proteins 1 located_in ISO (MGI:5781275|PMID:26797281) MGI PMID:26797281 MGI:5781275 NCBI chrNW_004936527:6,726,363...6,756,445 JBrowse link
G Sqstm1 sequestosome 1 ISO RGD PMID:15158159 RGD:13210572 NCBI chrNW_004936739:943,080...955,296 JBrowse link
Lewy body core term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:2,114,478...2,115,969 JBrowse link
G Fbxo7 F-box protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:7,261,442...7,276,779 JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:9,091,115...9,102,101 JBrowse link
Lewy body corona term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:7,261,442...7,276,779 JBrowse link
neurofibrillary tangle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936675:499,745...513,515 JBrowse link
G Mapt microtubule associated protein tau located_in ISO (PMID:2484340) CAFA PMID:2484340 NCBI chrNW_004936541:2,381,411...2,479,984 JBrowse link
G Nefh neurofilament heavy chain located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936657:3,443,406...3,453,096 JBrowse link
G Nefm neurofilament medium chain located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936757:1,662,905...1,668,707 JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:13,785,638...13,885,931 JBrowse link
nuclear inclusion body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn1 ataxin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936552:2,498,711...2,521,225 JBrowse link
G Atxn3 ataxin 3 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936733:306,400...347,161 JBrowse link
G LOC101973872 bcl-2-like protein 2 located_in ISO (PMID:27209344) RGD
UniProt
PMID:18255312 PMID:27209344 RGD:9686377 NCBI chrNW_004936722:1,039,970...1,044,942 JBrowse link
G Nbn nibrin located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936544:3,773,828...3,812,673 JBrowse link
G Nup153 nucleoporin 153 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936552:3,529,506...3,588,830 JBrowse link
G Nup98 nucleoporin 98 and 96 precursor located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:1,112,724...1,219,790 JBrowse link
G Nxf1 nuclear RNA export factor 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936581:488,691...501,323 JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase located_in ISO (PMID:22036607) UniProt PMID:22036607 NCBI chrNW_004936602:4,030,353...4,134,119 JBrowse link
G Ranbp2 RAN binding protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936829:261,017...333,910 JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936523:8,563,662...8,634,576 JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:328,767...330,963 JBrowse link
G Tpr translocated promoter region, nuclear basket protein located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936481:4,050,693...4,111,682 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 15332
    cellular anatomical entity 15218
      intracellular anatomical structure 11674
        inclusion body 81
          Bunina body 0
          Lewy body + 7
          Lewy body-like hyaline inclusion 0
          PHA granule 0
          Pick body 0
          aggresome 38
          fibrillary inclusion 0
          glial cytoplasmic inclusion 1
          hyaline inclusion 0
          laminated body + 0
          nematosome 0
          neurofibrillary tangle 5
          nuclear inclusion body + 12
          skein-like inclusion 0
paths to the root