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ONTOLOGY REPORT - ANNOTATIONS


Term:inclusion body
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Accession:GO:0016234 term browser browse the term
Definition:A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers.
Synonyms:narrow_synonym: neuronal cytoplasmic inclusion
 related_synonym: cellular inclusion
 xref: NIF_Subcellular:sao120573470;   Wikipedia:Inclusion_bodies



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inclusion body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:50,039,661...50,112,543
Ensembl chr 6:50,041,947...50,112,279
JBrowse link
G BAG5 BAG cochaperone 5 located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:71,318,730...71,324,743
Ensembl chr 8:71,321,625...71,322,992
JBrowse link
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 located_in ISO (PMID:15936278) BHF-UCL PMID:15936278 NCBI chr37:25,826,496...25,834,011
Ensembl chr37:25,827,713...25,833,144
JBrowse link
G GYS1 glycogen synthase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,401,056...107,417,273
Ensembl chr 1:107,401,114...107,417,122
JBrowse link
G HAP1 huntingtin associated protein 1 located_in ISO (PMID:21386698) UniProt PMID:21386698 NCBI chr 9:21,065,770...21,074,462
Ensembl chr 9:21,065,846...21,072,991
JBrowse link
G HDAC6 histone deacetylase 6 located_in ISO (PMID:16192271) BHF-UCL PMID:16192271 NCBI chr  X:42,004,268...42,024,726
Ensembl chr  X:42,004,591...42,024,427
JBrowse link
G HSP70 heat shock protein 70 located_in ISO (PMID:15603737) BHF-UCL PMID:15603737 NCBI chr12:1,285,282...1,287,670 JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO pseudovacuole RGD PMID:18445155 RGD:5686867 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940
JBrowse link
G HTT huntingtin located_in ISO (PMID:17947297)
(MGI:3522382|PMID:15615787)
CAFA
MGI
PMID:15615787 PMID:17947297 MGI:3522382 NCBI chr 3:61,076,934...61,221,462
Ensembl chr 3:61,079,904...61,330,290
JBrowse link
G IAPP islet amyloid polypeptide located_in ISO (PMID:22944668) UniProt PMID:22944668 NCBI chr27:26,295,481...26,299,967
Ensembl chr27:26,295,481...26,299,967
JBrowse link
G KEAP1 kelch like ECH associated protein 1 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr20:50,651,070...50,661,178
Ensembl chr20:50,650,711...50,658,496
JBrowse link
G LOC100687259 26S proteasome regulatory subunit 10B ISO RGD PMID:18986984 RGD:7242199 NCBI chr32:35,814,756...35,816,311 JBrowse link
G LRRK2 leucine rich repeat kinase 2 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870
JBrowse link
G MIOX myo-inositol oxygenase located_in ISO (PMID:11716759) UniProt PMID:11716759 NCBI chr10:16,813,532...16,815,930
Ensembl chr10:16,813,545...16,818,015
JBrowse link
G MT-III transcription initiation factor TFIID subunit 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,624,845...59,630,386 JBrowse link
G PRNP prion protein located_in IEA Ensembl GO_REF:0000107 NCBI chr24:16,845,224...16,862,319
Ensembl chr24:16,846,207...16,859,815
JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 ISO RGD PMID:18986984 RGD:7242199 NCBI chr 1:113,548,351...113,557,725
Ensembl chr 1:113,548,373...113,557,630
JBrowse link
G PSMC5 proteasome 26S subunit, ATPase 5 ISO RGD PMID:18986984 RGD:7242199 NCBI chr 9:11,783,422...11,787,624
Ensembl chr 9:11,783,466...11,787,617
JBrowse link
G RAD50 RAD50 double strand break repair protein ISO Ad5-transformed BRK cells RGD PMID:18212738 RGD:2300253 NCBI chr11:20,836,863...20,928,930
Ensembl chr11:20,836,879...20,928,819
JBrowse link
G SNCA synuclein alpha located_in IEA Ensembl GO_REF:0000107 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383
JBrowse link
G SNCB synuclein beta located_in IEA Ensembl GO_REF:0000107 NCBI chr 4:36,710,236...36,719,455
Ensembl chr 4:36,616,039...36,764,501
JBrowse link
G SQSTM1 sequestosome 1 located_in ISO (PMID:20168092) UniProt PMID:20168092 NCBI chr11:1,859,776...1,869,289
Ensembl chr11:1,859,465...1,870,755
JBrowse link
G WDFY3 WD repeat and FYVE domain containing 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr32:8,430,856...8,662,988
Ensembl chr32:8,433,080...8,695,859
JBrowse link
G ZP2 zona pellucida glycoprotein 2 located_in IDA (PMID:12052239) UniProt
UniProt
PMID:12052239 NCBI chr 6:24,230,202...24,242,441
Ensembl chr 6:24,230,201...24,242,451
JBrowse link
aggresome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CABIN1 calcineurin binding protein 1 located_in ISO HPA GO_REF:0000052 NCBI chr26:28,366,264...28,517,570
Ensembl chr26:28,366,265...28,517,656
JBrowse link
G CARD14 caspase recruitment domain family member 14 located_in ISO HPA GO_REF:0000052 NCBI chr 9:1,547,645...1,571,567
Ensembl chr 9:1,547,686...1,573,581
JBrowse link
G CLU clusterin ISO RGD PMID:12799419 RGD:1582417 NCBI chr25:29,982,811...29,999,565
Ensembl chr25:29,982,811...29,999,563
JBrowse link
G CPNE1 copine 1 located_in ISO HPA GO_REF:0000052 NCBI chr24:24,554,636...24,589,748
Ensembl chr24:24,554,636...24,589,731
JBrowse link
G DVL2 dishevelled segment polarity protein 2 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:32,194,326...32,201,922
Ensembl chr 5:32,194,313...32,201,857
JBrowse link
G EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 located_in ISO HPA GO_REF:0000052 NCBI chr20:12,444,013...12,473,188
Ensembl chr20:12,452,730...12,472,069
JBrowse link
G EEF2 eukaryotic translation elongation factor 2 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr20:55,577,413...55,586,422
Ensembl chr20:55,522,213...55,586,126
JBrowse link
G EPS15 epidermal growth factor receptor pathway substrate 15 located_in ISO (PMID:16159959) UniProt PMID:16159959 NCBI chr15:9,834,285...9,895,755
Ensembl chr15:9,787,260...9,893,540
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase located_in ISO HPA GO_REF:0000052 NCBI chr 2:72,678,858...72,692,417
Ensembl chr 2:72,680,675...72,690,251
JBrowse link
G HDAC6 histone deacetylase 6 located_in ISO (PMID:14675537) BHF-UCL PMID:14675537 NCBI chr  X:42,004,268...42,024,726
Ensembl chr  X:42,004,591...42,024,427
JBrowse link
G HOXC9 homeobox C9 located_in ISO HPA GO_REF:0000052
G HOXD3 homeobox D3 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr36:19,961,393...19,981,672
Ensembl chr36:19,960,761...19,980,525
JBrowse link
G HSP70 heat shock protein 70 located_in ISO (PMID:15885686) UniProt PMID:15885686 NCBI chr12:1,285,282...1,287,670 JBrowse link
G HSPB7 heat shock protein family B (small) member 7 located_in ISO HPA GO_REF:0000052 NCBI chr 2:81,628,051...81,631,939
Ensembl chr 2:81,619,999...81,630,483
JBrowse link
G KLF8 Kruppel like factor 8 located_in ISO HPA GO_REF:0000052 NCBI chr  X:47,662,824...47,758,628
Ensembl chr  X:47,662,253...47,755,578
JBrowse link
G KLHL14 kelch like family member 14 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:56,973,284...57,089,128
Ensembl chr 7:56,974,692...57,088,039
JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,302,583...106,331,353
Ensembl chr 1:106,302,574...106,331,385
JBrowse link
G PRDM16 PR/SET domain 16 located_in ISO HPA GO_REF:0000052 NCBI chr 5:57,805,951...58,018,817
Ensembl chr 5:57,730,370...58,017,976
JBrowse link
G PRKCQ protein kinase C theta located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
G PSAP prosaposin located_in ISO (MGI:4819645|PMID:20498017) MGI PMID:20498017 MGI:4819645 NCBI chr 4:22,571,095...22,603,880
Ensembl chr 4:22,572,153...22,603,848
JBrowse link
G PSEN1 presenilin 1 located_in ISS
IEA
UniProt
UniProt
Ensembl
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532
JBrowse link
G RANGAP1 Ran GTPase activating protein 1 located_in ISO HPA GO_REF:0000052 NCBI chr10:23,953,877...23,985,622
Ensembl chr10:23,953,912...24,003,162
JBrowse link
G RNF32 ring finger protein 32 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:19,237,069...19,297,984
Ensembl chr16:19,235,972...19,280,301
JBrowse link
G SFMBT2 Scm like with four mbt domains 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:28,637,365...28,856,505
Ensembl chr 2:28,661,058...28,853,364
JBrowse link
G SQSTM1 sequestosome 1 located_in
is_active_in
ISO
IBA
(MGI:5446594|PMID:22792322)
(PMID:21873635)
MGI
GO_Central
PMID:21873635 PMID:22792322 MGI:5446594 NCBI chr11:1,859,776...1,869,289
Ensembl chr11:1,859,465...1,870,755
JBrowse link
G STRADB STE20 related adaptor beta located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr37:10,521,643...10,557,611
Ensembl chr37:10,521,574...10,557,231
JBrowse link
G TDP2 tyrosyl-DNA phosphodiesterase 2 located_in ISO HPA GO_REF:0000052 NCBI chr35:22,693,203...22,707,054
Ensembl chr35:22,693,110...22,707,008
JBrowse link
G TRIM37 tripartite motif containing 37 located_in
is_active_in
ISO
IBA
(PMID:15885686)
(PMID:21873635)
UniProt
GO_Central
PMID:15885686 PMID:21873635 NCBI chr 9:33,446,903...33,687,650
Ensembl chr 9:33,446,918...33,687,555
JBrowse link
G TRIM50 tripartite motif containing 50 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,868,484...6,882,964
Ensembl chr 6:6,868,117...6,882,576
JBrowse link
G TRIM66 tripartite motif containing 66 located_in ISO HPA GO_REF:0000052 NCBI chr21:32,037,874...32,097,362
Ensembl chr21:32,044,841...32,097,357
JBrowse link
G UBD ubiquitin D located_in ISO (PMID:19033385) UniProt PMID:19033385 NCBI chr35:26,426,919...26,436,189 JBrowse link
G UBQLN1 ubiquilin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:75,767,345...75,812,278
Ensembl chr 1:75,767,188...75,838,051
JBrowse link
G UCMA upper zone of growth plate and cartilage matrix associated located_in ISO (MGI:4421086|PMID:19819238) MGI PMID:19819238 MGI:4421086 NCBI chr 2:23,287,410...23,307,116
Ensembl chr 2:23,287,551...23,298,035
JBrowse link
G URB2 URB2 ribosome biogenesis homolog located_in ISO HPA GO_REF:0000052 NCBI chr 4:9,617,824...9,645,763
Ensembl chr 4:9,616,020...9,645,835
JBrowse link
G XRN2 5'-3' exoribonuclease 2 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr24:2,042,521...2,128,942
Ensembl chr24:2,042,888...2,128,867
JBrowse link
G ZBTB14 zinc finger and BTB domain containing 14 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:71,680,692...71,687,651
Ensembl chr 7:71,682,578...71,687,703
JBrowse link
G ZDHHC17 zinc finger DHHC-type palmitoyltransferase 17 located_in ISO HPA GO_REF:0000052 NCBI chr15:19,631,719...19,727,089
Ensembl chr15:19,499,445...19,724,341
JBrowse link
classical Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO7 F-box protein 7 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:30,928,059...30,948,858
Ensembl chr10:30,928,329...30,948,977
JBrowse link
glial cytoplasmic inclusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO7 F-box protein 7 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:30,928,059...30,948,858
Ensembl chr10:30,928,329...30,948,977
JBrowse link
Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 located_in ISO (PMID:21590270) UniProt PMID:21590270 NCBI chr30:35,927,277...36,040,168
Ensembl chr30:35,927,233...36,108,381
JBrowse link
G GPX1 glutathione peroxidase 1 colocalizes_with
located_in
ISO
IEA
(PMID:18853169) ParkinsonsUK-UCL
Ensembl
Ensembl
PMID:18853169 GO_REF:0000107 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260
JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 located_in ISO (MGI:5781275|PMID:26797281) MGI PMID:26797281 MGI:5781275 NCBI chr16:15,355,237...15,382,284
Ensembl chr16:15,352,476...15,381,095
JBrowse link
G SQSTM1 sequestosome 1 ISO RGD PMID:15158159 RGD:13210572 NCBI chr11:1,859,776...1,869,289
Ensembl chr11:1,859,465...1,870,755
JBrowse link
Lewy body core term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993
JBrowse link
G FBXO7 F-box protein 7 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:30,928,059...30,948,858
Ensembl chr10:30,928,329...30,948,977
JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:59,388,492...59,400,028
Ensembl chr 2:59,388,494...59,400,003
JBrowse link
Lewy body corona term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO7 F-box protein 7 located_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:30,928,059...30,948,858
Ensembl chr10:30,928,329...30,948,977
JBrowse link
neurofibrillary tangle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLU clusterin located_in ISO (PMID:15897157), (PMID:9560017) Alzheimers_University_of_Toronto PMID:9560017 PMID:15897157 NCBI chr25:29,982,811...29,999,565
Ensembl chr25:29,982,811...29,999,563
JBrowse link
G MAPT microtubule associated protein tau located_in ISO (PMID:2484340) CAFA PMID:2484340 NCBI chr 9:9,572,174...9,674,082
Ensembl chr 9:9,570,557...9,674,349
JBrowse link
G NEFH neurofilament heavy chain located_in ISO (PMID:21828286) BHF-UCL PMID:21828286 NCBI chr26:22,726,523...22,735,129
Ensembl chr26:22,726,526...22,735,125
JBrowse link
G NEFM neurofilament medium chain located_in ISO (PMID:21828286) BHF-UCL PMID:21828286 NCBI chr25:32,493,517...32,498,615
Ensembl chr25:32,493,675...32,498,570
JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein located_in IEA Ensembl GO_REF:0000107 NCBI chr21:13,437,819...13,540,167
Ensembl chr21:13,437,925...13,539,616
JBrowse link
nuclear inclusion body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATXN1 ataxin 1 located_in ISO (MGI:3522382|PMID:15615787)
(PMID:15615787)
MGI
UniProt
PMID:15615787 MGI:3522382 NCBI chr35:15,458,498...15,863,829
Ensembl chr35:15,452,135...15,649,747
JBrowse link
G ATXN3 ataxin 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:1,318,440...1,354,814
Ensembl chr 8:1,247,155...1,354,720
JBrowse link
G LOC488622 myeloid cell nuclear differentiation antigen located_in ISO (MGI:5487541|PMID:12513910) UniProt PMID:12513910 MGI:5487541 NCBI chr38:22,874,345...22,892,362 JBrowse link
G NBN nibrin located_in IEA Ensembl GO_REF:0000107 NCBI chr29:35,416,093...35,477,569
Ensembl chr29:35,416,093...35,477,563
JBrowse link
G NUP153 nucleoporin 153 located_in ISO (PMID:11839768) UniProt PMID:11839768 RGD:8553300 NCBI chr35:16,517,992...16,598,472
Ensembl chr35:16,519,109...16,589,537
JBrowse link
G NUP98 nucleoporin 98 and 96 precursor located_in IEA Ensembl GO_REF:0000107 NCBI chr21:26,231,585...26,348,019
Ensembl chr21:26,220,963...26,336,020
JBrowse link
G NXF1 nuclear RNA export factor 1 located_in ISO (MGI:3522382|PMID:15615787) MGI PMID:15615787 MGI:3522382 NCBI chr18:53,884,512...53,895,168
Ensembl chr18:53,884,546...53,895,162
JBrowse link
G PABPN1 poly(A) binding protein nuclear 1 located_in ISO (PMID:27209344) RGD
UniProt
PMID:18255312 PMID:27209344 RGD:9686377 NCBI chr 8:3,580,768...3,585,546
Ensembl chr 8:3,569,399...3,586,070
JBrowse link
G RAD18 RAD18 E3 ubiquitin protein ligase located_in IEA Ensembl GO_REF:0000107 NCBI chr20:9,163,322...9,271,224
Ensembl chr20:9,163,428...9,263,730
JBrowse link
G RANBP2 RAN binding protein 2 located_in ISO (PMID:11839768) UniProt PMID:11839768 NCBI chr10:35,088,175...35,181,248
Ensembl chr10:35,088,872...35,181,129
JBrowse link
G SLF1 SMC5-SMC6 complex localization factor 1 located_in ISO (MGI:5688834|PMID:22036607) UniProt PMID:22036607 MGI:5688834 NCBI chr 3:14,792,851...14,877,024
Ensembl chr 3:14,793,363...14,869,755
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 located_in ISO (PMID:16831871) BHF-UCL PMID:16831871 NCBI chr 6:39,893,492...39,895,385
Ensembl chr 6:39,893,670...39,897,573
JBrowse link
G TPR translocated promoter region, nuclear basket protein located_in ISO PMID:11839768
(PMID:11514627), (PMID:11839768)
(MGI:5487541|PMID:12513910)
UniProt PMID:11514627 PMID:11839768 PMID:12513910 MGI:5487541 RGD:8553300 NCBI chr 7:19,376,951...19,442,368
Ensembl chr 7:19,376,975...19,442,303
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 16921
    cellular anatomical entity 16667
      intracellular anatomical structure 12925
        inclusion body 82
          Bunina body 0
          Lewy body + 7
          Lewy body-like hyaline inclusion 0
          PHA granule 0
          Pick body 0
          aggresome 38
          fibrillary inclusion 0
          glial cytoplasmic inclusion 1
          hyaline inclusion 0
          laminated body + 0
          nematosome 0
          neurofibrillary tangle 5
          nuclear inclusion body + 13
          skein-like inclusion 0
paths to the root