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ONTOLOGY REPORT - ANNOTATIONS

Term:inclusion body
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Accession:GO:0016234 term browser browse the term
Definition:A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers.
Synonyms:narrow_synonym: neuronal cytoplasmic inclusion
 related_synonym: cellular inclusion
 xref: NIF_Subcellular:sao120573470;   Wikipedia:Inclusion_bodies

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inclusion body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agl amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase located_in ISO (MGI:3758968|PMID:17908927) MGI PMID:17908927 MGI:3758968 NCBI chrNW_004955435:4,622,142...4,684,439
Ensembl chrNW_004955435:4,621,991...4,688,139 		JBrowse link
G Bag5 BAG cochaperone 5 located_in ISO (PMID:15603737) BHF-UCL PMID:15603737 NCBI chrNW_004955538:2,412,297...2,416,094
Ensembl chrNW_004955538:2,412,297...2,415,132 		JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 located_in ISO (PMID:15936278) BHF-UCL PMID:15936278 NCBI chrNW_004955453:14,147,286...14,154,396
Ensembl chrNW_004955453:14,148,070...14,154,670 		JBrowse link
G Gys1 glycogen synthase 1 located_in ISO (MGI:3758968|PMID:17908927) MGI PMID:17908927 MGI:3758968 NCBI chrNW_004955559:1,674,969...1,690,098
Ensembl chrNW_004955559:1,674,969...1,690,098 		JBrowse link
G Hdac6 histone deacetylase 6 located_in ISO (PMID:16192271) BHF-UCL PMID:16192271 NCBI chrNW_004955543:348,314...378,391
Ensembl chrNW_004955543:348,019...378,071 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO pseudovacuole RGD PMID:18445155 RGD:5686867 NCBI chrNW_004955437:9,872,649...9,878,459
Ensembl chrNW_004955437:9,873,908...9,878,459 		JBrowse link
G Htt huntingtin located_in ISO (PMID:17947297)
(MGI:3522382|PMID:15615787)		 CAFA
MGI		 PMID:15615787 PMID:17947297 MGI:3522382 NCBI chrNW_004955514:1,906,189...2,042,357
Ensembl chrNW_004955514:1,906,502...2,038,889 		JBrowse link
G Iapp islet amyloid polypeptide located_in ISO (PMID:22944668) UniProt PMID:22944668 NCBI chrNW_004955413:16,834,940...16,841,071
Ensembl chrNW_004955413:16,835,037...16,840,682 		JBrowse link
G Keap1 kelch like ECH associated protein 1 located_in ISO (PMID:20452972)
(MGI:4819475|PMID:20421418), (MGI:5009358|PMID:20173742)		 UniProt PMID:20173742 PMID:20421418 PMID:20452972 MGI:4819475 MGI:5009358 NCBI chrNW_004955495:1,704,695...1,711,339
Ensembl chrNW_004955495:1,704,695...1,711,290 		JBrowse link
G Lrrk2 leucine rich repeat kinase 2 located_in ISO (PMID:24403142) ParkinsonsUK-UCL PMID:24403142 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923 		JBrowse link
G Miox myo-inositol oxygenase located_in ISO (PMID:11716759) UniProt PMID:11716759 NCBI chrNW_004955413:33,476,097...33,478,539
Ensembl chrNW_004955413:33,476,033...33,478,539 		JBrowse link
G Prnp prion protein located_in ISO (PMID:20564047) CAFA PMID:20564047 NCBI chrNW_004955415:15,442,313...15,454,644
Ensembl chrNW_004955415:15,442,313...15,454,644 		JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 ISO RGD PMID:18986984 RGD:7242199 NCBI chrNW_004955578:1,113,445...1,120,050
Ensembl chrNW_004955578:1,113,445...1,120,370 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 ISO RGD PMID:18986984 RGD:7242199 NCBI chrNW_004955478:7,996,902...8,002,183
Ensembl chrNW_004955478:7,996,902...8,002,183 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 ISO RGD PMID:18986984 RGD:7242199 NCBI chrNW_004955409:10,454,210...10,474,872
Ensembl chrNW_004955409:10,452,615...10,475,100 		JBrowse link
G Rad50 RAD50 double strand break repair protein ISO Ad5-transformed BRK cells RGD PMID:18212738 RGD:2300253 NCBI chrNW_004955408:3,953,801...4,035,494 JBrowse link
G Snca synuclein alpha located_in ISO (PMID:17222866), (PMID:20039155)
(MGI:5516416|PMID:24076025), (MGI:5582171|PMID:17222866)		 ParkinsonsUK-UCL PMID:17222866 PMID:20039155 PMID:24076025 MGI:5516416 MGI:5582171 NCBI chrNW_004955405:854,011...962,741
Ensembl chrNW_004955405:853,946...965,403 		JBrowse link
G Sncb synuclein beta located_in ISO (PMID:17222866) ParkinsonsUK-UCL PMID:17222866 NCBI chrNW_004955408:28,894,204...28,903,095
Ensembl chrNW_004955408:28,894,204...28,903,095 		JBrowse link
G Sqstm1 sequestosome 1 located_in ISO (PMID:20168092) UniProt PMID:20168092 NCBI chrNW_004955408:757,426...764,989
Ensembl chrNW_004955408:757,426...771,615 		JBrowse link
G Wdfy3 WD repeat and FYVE domain containing 3 located_in ISO (PMID:20168092) UniProt PMID:20168092 NCBI chrNW_004955474:4,764,902...5,045,421
Ensembl chrNW_004955474:4,870,835...5,042,310 		JBrowse link
G Zp2 zona pellucida glycoprotein 2 located_in ISO (PMID:12052239) UniProt PMID:12052239 NCBI chrNW_004955493:400,868...412,660
Ensembl chrNW_004955493:400,868...412,596 		JBrowse link
aggresome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cabin1 calcineurin binding protein 1 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955455:8,162,365...8,312,932
Ensembl chrNW_004955455:8,162,315...8,312,909 		JBrowse link
G Card14 caspase recruitment domain family member 14 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955506:2,711,061...2,744,555
Ensembl chrNW_004955506:2,711,942...2,734,219 		JBrowse link
G Clu clusterin ISO RGD PMID:12799419 RGD:1582417 NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876 		JBrowse link
G Cpne1 copine 1 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955422:25,793,841...25,837,680
Ensembl chrNW_004955422:25,793,819...25,837,564
Ensembl chrNW_004955422:25,793,819...25,837,564 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955467:9,675,912...9,683,996
Ensembl chrNW_004955467:9,675,912...9,683,996 		JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955421:8,196,631...8,225,561
Ensembl chrNW_004955421:8,196,557...8,225,561 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955495:4,800,103...4,807,714
Ensembl chrNW_004955495:4,799,922...4,807,252 		JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 located_in ISO (PMID:16159959) UniProt PMID:16159959 NCBI chrNW_004955464:7,569,570...7,688,098
Ensembl chrNW_004955464:7,569,566...7,688,098 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955452:6,840,274...6,863,460
Ensembl chrNW_004955452:6,841,802...6,863,542 		JBrowse link
G Hdac6 histone deacetylase 6 located_in ISO (PMID:14675537) BHF-UCL PMID:14675537 NCBI chrNW_004955543:348,314...378,391
Ensembl chrNW_004955543:348,019...378,071 		JBrowse link
G Hoxc9 homeobox C9 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955458:1,258,364...1,261,510
Ensembl chrNW_004955458:1,258,364...1,261,510 		JBrowse link
G Hoxd3 homeobox D3 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955403:20,489,663...20,496,021 JBrowse link
G Hspb7 heat shock protein family B (small) member 7 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955527:2,219,462...2,222,824
Ensembl chrNW_004955527:2,219,462...2,222,824 		JBrowse link
G Klf8 Kruppel like factor 8 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955475:2,938,071...2,998,435
Ensembl chrNW_004955475:2,938,043...2,999,317 		JBrowse link
G Klhl14 kelch like family member 14 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955402:19,841,255...19,932,774
Ensembl chrNW_004955402:19,841,194...19,932,774 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955559:712,375...730,551
Ensembl chrNW_004955559:712,321...725,661 		JBrowse link
G Prdm16 PR/SET domain 16 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955486:8,139,848...8,327,788
Ensembl chrNW_004955486:8,137,531...8,327,977 		JBrowse link
G Prkcq protein kinase C theta located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955421:23,072,607...23,151,591
Ensembl chrNW_004955421:23,070,955...23,175,699 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase located_in ISO (PMID:14645198) BHF-UCL PMID:14645198 NCBI chrNW_004955439:18,664,230...19,953,358
Ensembl chrNW_004955439:18,664,379...19,951,152 		JBrowse link
G Psap prosaposin located_in ISO (MGI:4819645|PMID:20498017) MGI PMID:20498017 MGI:4819645 NCBI chrNW_004955437:19,667,252...19,683,669 JBrowse link
G Psen1 presenilin 1 located_in ISO (PMID:21143716) UniProt PMID:21143716 NCBI chrNW_004955523:2,128,529...2,210,737
Ensembl chrNW_004955523:2,128,529...2,210,737 		JBrowse link
G Rangap1 Ran GTPase activating protein 1 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955413:26,869,487...26,894,192
Ensembl chrNW_004955413:26,867,812...26,890,284 		JBrowse link
G Rnf32 ring finger protein 32 located_in ISO (PMID:11890671) MGI PMID:11890671 NCBI chrNW_004955491:9,128,998...9,154,082
Ensembl chrNW_004955491:9,130,214...9,153,851 		JBrowse link
G Sfmbt2 Scm like with four mbt domains 2 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955421:23,691,648...23,913,781 JBrowse link
G Sqstm1 sequestosome 1 located_in ISO (MGI:5446594|PMID:22792322) MGI PMID:22792322 MGI:5446594 NCBI chrNW_004955408:757,426...764,989
Ensembl chrNW_004955408:757,426...771,615 		JBrowse link
G Stradb STE20 related adaptor beta located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955403:181,120...198,882
Ensembl chrNW_004955403:181,120...198,885 		JBrowse link
G Tdp2 tyrosyl-DNA phosphodiesterase 2 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955483:2,375,213...2,385,354
Ensembl chrNW_004955483:2,375,313...2,388,892 		JBrowse link
G Trim37 tripartite motif containing 37 located_in ISO (PMID:15885686) UniProt PMID:15885686 NCBI chrNW_004955451:3,839,757...4,014,178
Ensembl chrNW_004955451:3,878,416...3,989,208 		JBrowse link
G Trim66 tripartite motif containing 66 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955414:24,405,986...24,459,729
Ensembl chrNW_004955414:24,406,205...24,459,601 		JBrowse link
G Ubd ubiquitin D located_in ISO (PMID:19033385) UniProt PMID:19033385 NCBI chrNW_004955583:29,438...29,873
Ensembl chrNW_004955583:29,438...31,555 		JBrowse link
G Ubqln1 ubiquilin 1 located_in ISO (PMID:16159959), (PMID:21143716) UniProt PMID:16159959 PMID:21143716 NCBI chrNW_004955432:3,575,034...3,617,029
Ensembl chrNW_004955432:3,575,272...3,616,691 		JBrowse link
G Ucma upper zone of growth plate and cartilage matrix associated located_in ISO (MGI:4421086|PMID:19819238) MGI PMID:19819238 MGI:4421086 NCBI chrNW_004955462:1,195,738...1,204,255
Ensembl chrNW_004955462:1,195,608...1,204,266 		JBrowse link
G Urb2 URB2 ribosome biogenesis homolog located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955492:8,451,367...8,478,213
Ensembl chrNW_004955492:8,451,048...8,478,728 		JBrowse link
G Xrn2 5'-3' exoribonuclease 2 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955415:29,107,060...29,175,374
Ensembl chrNW_004955415:29,107,034...29,175,538 		JBrowse link
G Zbtb14 zinc finger and BTB domain containing 14 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955402:5,750,877...5,757,370
Ensembl chrNW_004955402:5,750,877...5,757,370 		JBrowse link
G Zdhhc17 zinc finger DHHC-type palmitoyltransferase 17 located_in ISO HPA GO_REF:0000052 NCBI chrNW_004955405:15,915,756...15,997,777
Ensembl chrNW_004955405:15,915,756...15,997,777 		JBrowse link
classical Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in ISO (PMID:23656991) ParkinsonsUK-UCL PMID:23656991 NCBI chrNW_004955405:41,429,421...41,449,670
Ensembl chrNW_004955405:41,433,082...41,453,909 		JBrowse link
glial cytoplasmic inclusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in ISO (PMID:23656991) ParkinsonsUK-UCL PMID:23656991 NCBI chrNW_004955405:41,429,421...41,449,670
Ensembl chrNW_004955405:41,433,082...41,453,909 		JBrowse link
Lewy body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 located_in ISO (PMID:21590270) UniProt PMID:21590270 NCBI chrNW_004955450:4,683,118...4,737,793
Ensembl chrNW_004955450:4,683,118...4,737,994 		JBrowse link
G Gpx1 glutathione peroxidase 1 colocalizes_with ISO (PMID:18853169) ParkinsonsUK-UCL PMID:18853169 NCBI chrNW_004955532:1,298,336...1,298,830 JBrowse link
G Nub1 negative regulator of ubiquitin like proteins 1 located_in ISO (MGI:5781275|PMID:26797281) MGI PMID:26797281 MGI:5781275 NCBI chrNW_004955491:5,709,791...5,737,620
Ensembl chrNW_004955491:5,709,791...5,739,079 		JBrowse link
G Sqstm1 sequestosome 1 ISO RGD PMID:15158159 RGD:13210572 NCBI chrNW_004955408:757,426...764,989
Ensembl chrNW_004955408:757,426...771,615 		JBrowse link
Lewy body core term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 located_in ISO (PMID:23392669) ParkinsonsUK-UCL PMID:23392669 NCBI chrNW_004955413:25,406,589...25,408,727
Ensembl chrNW_004955413:25,406,589...25,412,218 		JBrowse link
G Fbxo7 F-box protein 7 located_in ISO (PMID:23656991) ParkinsonsUK-UCL PMID:23656991 NCBI chrNW_004955405:41,429,421...41,449,670
Ensembl chrNW_004955405:41,433,082...41,453,909 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 located_in ISO (PMID:19788048) ParkinsonsUK-UCL PMID:19788048 NCBI chrNW_004955433:14,609,275...14,621,774
Ensembl chrNW_004955433:14,608,375...14,621,839 		JBrowse link
Lewy body corona term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 located_in ISO (PMID:23656991) ParkinsonsUK-UCL PMID:23656991 NCBI chrNW_004955405:41,429,421...41,449,670
Ensembl chrNW_004955405:41,433,082...41,453,909 		JBrowse link
neurofibrillary tangle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin located_in ISO (PMID:15897157), (PMID:9560017) Alzheimers_University_of_Toronto PMID:9560017 PMID:15897157 NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876 		JBrowse link
G Mapt microtubule associated protein tau located_in ISO (PMID:2484340) CAFA PMID:2484340 NCBI chrNW_004955478:10,222,439...10,271,439
Ensembl chrNW_004955478:10,225,823...10,271,442 		JBrowse link
G Nefh neurofilament heavy chain located_in ISO (PMID:21828286) BHF-UCL PMID:21828286 NCBI chrNW_004955455:3,735,330...3,744,714
Ensembl chrNW_004955455:3,735,410...3,744,107 		JBrowse link
G Nefm neurofilament medium chain located_in ISO (PMID:21828286) BHF-UCL PMID:21828286 NCBI chrNW_004955403:47,920,408...47,926,922 JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein located_in ISO (PMID:23589030) Alzheimers_University_of_Toronto PMID:23589030 NCBI chrNW_004955414:6,871,220...6,970,569
Ensembl chrNW_004955414:6,871,520...6,969,208 		JBrowse link
nuclear inclusion body term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn1 ataxin 1 located_in ISO (PMID:15615787)
(MGI:3522382|PMID:15615787)		 UniProt
MGI		 PMID:15615787 MGI:3522382 NCBI chrNW_004955483:9,159,877...9,559,453
Ensembl chrNW_004955483:9,536,261...9,552,321 		JBrowse link
G Atxn3 ataxin 3 located_in ISO (MGI:3716223|PMID:17626202) MGI PMID:17626202 MGI:3716223 NCBI chrNW_004955438:14,405,415...14,443,457 JBrowse link
G Ifi16 interferon gamma inducible protein 16 located_in ISO (MGI:5487541|PMID:12513910) UniProt PMID:12513910 MGI:5487541 NCBI chrNW_004955468:10,828,726...10,845,853 JBrowse link
G Nbn nibrin located_in ISO (PMID:12447371) UniProt PMID:12447371 NCBI chrNW_004955417:6,840,916...6,880,479
Ensembl chrNW_004955417:6,839,312...6,880,133 		JBrowse link
G Nup153 nucleoporin 153 located_in ISO PMID:11839768
(PMID:11839768)		 UniProt PMID:11839768 RGD:8553300 NCBI chrNW_004955483:8,377,253...8,457,018
Ensembl chrNW_004955483:8,388,066...8,455,965 		JBrowse link
G Nup98 nucleoporin 98 and 96 precursor located_in ISO (PMID:11839768) UniProt PMID:11839768 RGD:8553300 NCBI chrNW_004955414:19,499,577...19,607,075
Ensembl chrNW_004955414:19,499,406...19,607,075 		JBrowse link
G Nxf1 nuclear RNA export factor 1 located_in ISO (MGI:3522382|PMID:15615787) MGI PMID:15615787 MGI:3522382 NCBI chrNW_004955599:439,773...450,834
Ensembl chrNW_004955599:439,775...454,300 		JBrowse link
G Pabpn1 poly(A) binding protein nuclear 1 located_in ISO (PMID:27209344) RGD
UniProt		 PMID:18255312 PMID:27209344 RGD:9686377 NCBI chrNW_004955409:37,000,423...37,004,823
Ensembl chrNW_004955409:37,000,451...37,004,682 		JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase located_in ISO (PMID:22036607) UniProt PMID:22036607 NCBI chrNW_004955561:463,586...602,354
Ensembl chrNW_004955561:464,343...599,789 		JBrowse link
G Ranbp2 RAN binding protein 2 located_in ISO (PMID:11839768) UniProt PMID:11839768 NCBI chrNW_004955470:12,180,426...12,247,737
Ensembl chrNW_004955470:12,180,544...12,249,555 		JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 located_in ISO (MGI:5688834|PMID:22036607) UniProt PMID:22036607 MGI:5688834 NCBI chrNW_004955418:17,756,610...17,818,552
Ensembl chrNW_004955418:17,756,861...17,810,663 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 located_in ISO (PMID:16831871) BHF-UCL PMID:16831871 NCBI chrNW_004955442:16,521,130...16,523,733
Ensembl chrNW_004955442:16,521,130...16,523,468 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein located_in ISO (PMID:11514627), (PMID:11839768)
(MGI:5487541|PMID:12513910)		 UniProt PMID:11514627 PMID:11839768 PMID:12513910 MGI:5487541 RGD:8553300 NCBI chrNW_004955406:24,742,525...24,805,989
Ensembl chrNW_004955406:24,742,525...24,805,989 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12360
    cellular anatomical entity 12202
      intracellular anatomical structure 10482
        inclusion body 78
          Bunina body 0
          Lewy body + 7
          Lewy body-like hyaline inclusion 0
          PHA granule 0
          Pick body 0
          aggresome 36
          fibrillary inclusion 0
          glial cytoplasmic inclusion 1
          hyaline inclusion 0
          laminated body + 0
          nematosome 0
          neurofibrillary tangle 5
          nuclear inclusion body + 13
          skein-like inclusion 0
paths to the root