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ONTOLOGY REPORT - ANNOTATIONS


Term:iron-sulfur cluster assembly
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Accession:GO:0016226 term browser browse the term
Definition:The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
Synonyms:exact_synonym: iron-sulphur cluster assembly
 related_synonym: iron-sulfur cluster biosynthesis



show annotations for term's descendants           Sort by:
 
iron-sulfur cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 involved_in IMP (MGI:6695684|PMID:30765471) UniProt PMID:30765471 MGI:6695684 NCBI chr  X:103,324,171...103,457,452
Ensembl chr  X:103,324,263...103,457,462
JBrowse link
G AK157302 cDNA sequence AK157302 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr13:21,679,393...21,681,307
Ensembl chr13:21,679,393...21,681,316
JBrowse link
G Bola2 bolA-like 2 (E. coli) involved_in ISO (PMID:27519415) ComplexPortal PMID:27519415 NCBI chr 7:126,295,172...126,295,865
Ensembl chr 7:126,294,573...126,298,970
JBrowse link
G Ciao1 cytosolic iron-sulfur protein assembly 1 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 2:127,082,858...127,089,736
Ensembl chr 2:127,082,858...127,089,736
JBrowse link
G Ciao2a cytosolic iron-sulfur assembly component 2A involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:66,033,878...66,046,250
Ensembl chr 9:66,033,893...66,046,237
JBrowse link
G Ciao2b cytosolic iron-sulfur assembly component 2B involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 8:105,366,471...105,368,360
Ensembl chr 8:105,366,470...105,368,597
JBrowse link
G Ciao3 cytosolic iron-sulfur assembly component 3 involved_in
acts_upstream_of_or_within
ISO
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:4946832|PMID:21367862)
MGI
GO_Central
PMID:21367862 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:4946832 MGI:6201960 NCBI chr17:25,992,750...26,002,306
Ensembl chr17:25,992,750...26,002,306
JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:95,546,446...95,565,454
Ensembl chr 8:95,546,432...95,564,986
JBrowse link
G Fdx2 ferredoxin 2 involved_in IC (MGI:6867303|PMID:29097656) ComplexPortal PMID:29097656 MGI:6867303 NCBI chr 9:20,978,808...20,984,827
Ensembl chr 9:20,978,816...20,984,910
JBrowse link
G Fxn frataxin involved_in
acts_upstream_of_or_within
ISO
IMP
IC
(MGI:3611157|PMID:16278235)
(MGI:3770334|PMID:17597094)
(MGI:6867303|PMID:29097656)
MGI
ComplexPortal
PMID:16278235 PMID:17597094 PMID:29097656 GO_REF:0000096 MGI:3611157 MGI:3770334 MGI:4834177 MGI:6867303 NCBI chr19:24,236,909...24,257,954
Ensembl chr19:24,238,817...24,257,969
JBrowse link
G Glrx3 glutaredoxin 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:137,039,302...137,071,360
Ensembl chr 7:137,039,343...137,070,323
JBrowse link
G Hscb HscB iron-sulfur cluster co-chaperone involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:110,976,936...110,987,673
Ensembl chr 5:110,976,936...110,987,643
JBrowse link
G Hspa9 heat shock protein 9 involved_in ISO
IMP
(MGI:6094650|PMID:26702583) MGI
UniProt
PMID:26702583 GO_REF:0000096 MGI:4834177 MGI:6094650 NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410
JBrowse link
G Iba57 IBA57 homolog, iron-sulfur cluster assembly involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr11:59,046,194...59,055,391
Ensembl chr11:59,046,195...59,054,565
JBrowse link
G Isca1 iron-sulfur cluster assembly 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr13:59,903,229...59,917,603
Ensembl chr13:59,903,223...59,917,624
JBrowse link
G Isca2 iron-sulfur cluster assembly 2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr12:84,820,007...84,821,863
Ensembl chr12:84,820,025...84,821,862
JBrowse link
G Iscu iron-sulfur cluster assembly enzyme involved_in IC (MGI:6867303|PMID:29097656) ComplexPortal PMID:29097656 MGI:6867303 NCBI chr 5:113,910,479...113,916,349
Ensembl chr 5:113,910,809...113,916,349
JBrowse link
G Lyrm4 LYR motif containing 4 involved_in IBA
IC
(MGI:6201960|PMID:21873635)
(MGI:6867303|PMID:29097656)
GO_Central
ComplexPortal
PMID:21873635 PMID:29097656 MGI:6201960 MGI:6867303 NCBI chr13:36,162,780...36,301,340
Ensembl chr13:36,162,378...36,301,509
JBrowse link
G Mms19 MMS19 cytosolic iron-sulfur assembly component involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr19:41,932,146...41,969,603
Ensembl chr19:41,929,525...41,969,596
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 involved_in IC (MGI:6867303|PMID:29097656) ComplexPortal PMID:29097656 MGI:6867303 NCBI chr 7:121,686,038...121,701,071
Ensembl chr 7:121,684,626...121,701,109
JBrowse link
G Nfs1 nitrogen fixation gene 1 (S. cerevisiae) involved_in IBA
IC
(MGI:6201960|PMID:21873635)
(MGI:6867303|PMID:29097656)
GO_Central
ComplexPortal
PMID:21873635 PMID:29097656 MGI:6201960 MGI:6867303 NCBI chr 2:155,965,557...155,986,134
Ensembl chr 2:155,965,559...155,986,106
JBrowse link
G Nfu1 NFU1 iron-sulfur cluster scaffold involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 6:86,986,040...87,005,443
Ensembl chr 6:86,986,218...87,005,443
JBrowse link
G Nubp1 nucleotide binding protein 1 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr16:10,229,748...10,242,317
Ensembl chr16:10,229,812...10,242,292
JBrowse link
G Nubp2 nucleotide binding protein 2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr17:25,101,585...25,105,423
Ensembl chr17:25,101,585...25,105,323
JBrowse link
G Nubpl nucleotide binding protein-like involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr12:52,144,529...52,357,753
Ensembl chr12:52,144,520...52,359,527
JBrowse link
G Xdh xanthine dehydrogenase acts_upstream_of_or_within IDA (MGI:3770334|PMID:17597094) MGI PMID:17597094 MGI:3770334 NCBI chr17:74,190,890...74,257,369
Ensembl chr17:74,190,890...74,257,191
JBrowse link
[2Fe-2S] cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bola2 bolA-like 2 (E. coli) involved_in ISO (PMID:27519415) UniProt PMID:27519415 NCBI chr 7:126,295,172...126,295,865
Ensembl chr 7:126,294,573...126,298,970
JBrowse link
G Fxn frataxin involved_in ISO (PMID:24971490), (PMID:29576242) UniProt PMID:24971490 PMID:29576242 NCBI chr19:24,236,909...24,257,954
Ensembl chr19:24,238,817...24,257,969
JBrowse link
G Glrx3 glutaredoxin 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:137,039,302...137,071,360
Ensembl chr 7:137,039,343...137,070,323
JBrowse link
G Glrx5 glutaredoxin 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:104,998,877...105,007,170
Ensembl chr12:104,998,947...105,009,165
JBrowse link
G Hscb HscB iron-sulfur cluster co-chaperone involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 5:110,976,936...110,987,673
Ensembl chr 5:110,976,936...110,987,643
JBrowse link
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:113,910,479...113,916,349
Ensembl chr 5:113,910,809...113,916,349
JBrowse link
G Nfs1 nitrogen fixation gene 1 (S. cerevisiae) involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 2:155,965,557...155,986,134
Ensembl chr 2:155,965,559...155,986,106
JBrowse link
[4Fe-4S] cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxn frataxin acts_upstream_of
acts_upstream_of_or_within
ISO
IDA
(PMID:29576242)
(PMID:25597503)
UniProt
UniProt
PMID:25597503 PMID:29576242 NCBI chr19:24,236,909...24,257,954
Ensembl chr19:24,238,817...24,257,969
JBrowse link
G Iscu iron-sulfur cluster assembly enzyme acts_upstream_of_positive_effect
acts_upstream_of_or_within
involved_in
ISO
IDA
(PMID:29309586)
(PMID:25597503)
(PMID:23940031)
(PMID:16527810), (PMID:29576242)
UniProt
UniProt
MGI
PMID:16527810 PMID:23940031 PMID:25597503 PMID:29309586 PMID:29576242 GO_REF:0000096 MGI:4834177 NCBI chr 5:113,910,479...113,916,349
Ensembl chr 5:113,910,809...113,916,349
JBrowse link
G Lyrm4 LYR motif containing 4 acts_upstream_of_or_within IDA (PMID:25597503) UniProt PMID:25597503 NCBI chr13:36,162,780...36,301,340
Ensembl chr13:36,162,378...36,301,509
JBrowse link
G Nfs1 nitrogen fixation gene 1 (S. cerevisiae) acts_upstream_of
acts_upstream_of_or_within
ISO
IDA
(PMID:16527810)
(PMID:25597503)
UniProt
UniProt
PMID:16527810 PMID:25597503 NCBI chr 2:155,965,557...155,986,134
Ensembl chr 2:155,965,559...155,986,106
JBrowse link
iron incorporation into metallo-sulfur cluster term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxn frataxin involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr19:24,236,909...24,257,954
Ensembl chr19:24,238,817...24,257,969
JBrowse link
G Nfs1 nitrogen fixation gene 1 (S. cerevisiae) involved_in IDA
ISO
(MGI:3763294|PMID:16847322) HGNC-UCL
MGI
PMID:16847322 GO_REF:0000096 MGI:3763294 MGI:4834177 NCBI chr 2:155,965,557...155,986,134
Ensembl chr 2:155,965,559...155,986,106
JBrowse link
positive regulation of iron-sulfur cluster assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 involved_in ISO
IMP
(MGI:3619656|PMID:16467350) MGI
UniProt
PMID:16467350 GO_REF:0000096 MGI:3619656 MGI:4834177 NCBI chr  X:103,324,171...103,457,452
Ensembl chr  X:103,324,263...103,457,462
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28742
    metabolic process 11549
      cellular metabolic process 9731
        sulfur compound metabolic process 333
          iron-sulfur cluster assembly 27
            [2Fe-2S] cluster assembly + 7
            [4Fe-4S] cluster assembly + 3
            iron incorporation into metallo-sulfur cluster + 2
            iron-sulfur-molybdenum cofactor assembly + 0
            molybdenum incorporation into iron-sulfur cluster + 0
            negative regulation of iron-sulfur cluster assembly + 0
            nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide + 0
            nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide 0
            nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide 0
            nitrogenase P cluster assembly 0
            positive regulation of iron-sulfur cluster assembly + 1
            regulation of iron-sulfur cluster assembly + 1
Path 2
Term Annotations click to browse term
  biological_process 28742
    cellular process 17717
      cellular component organization or biogenesis 6748
        cellular component organization 6545
          cellular component assembly 2975
            metallo-sulfur cluster assembly 27
              iron-sulfur cluster assembly 27
                [2Fe-2S] cluster assembly + 7
                [4Fe-4S] cluster assembly + 3
                iron incorporation into metallo-sulfur cluster + 2
                iron-sulfur-molybdenum cofactor assembly + 0
                molybdenum incorporation into iron-sulfur cluster + 0
                negative regulation of iron-sulfur cluster assembly + 0
                nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide + 0
                nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide 0
                nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide 0
                nitrogenase P cluster assembly 0
                positive regulation of iron-sulfur cluster assembly + 1
                regulation of iron-sulfur cluster assembly + 1
paths to the root