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ONTOLOGY REPORT - ANNOTATIONS


Term:iron-sulfur cluster assembly
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Accession:GO:0016226 term browser browse the term
Definition:The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
Synonyms:exact_synonym: iron-sulphur cluster assembly
 related_synonym: iron-sulfur cluster biosynthesis


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iron-sulfur cluster assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ciao1 cytosolic iron-sulfur assembly component 1 JBrowse link 3 119,671,778 119,677,324 RGD:1600115
RGD:13792537
RGD:1624291
G Ciao2a cytosolic iron-sulfur assembly component 2A JBrowse link 8 71,786,336 71,798,258 RGD:1624291
G Ciao2b cytosolic iron-sulfur assembly component 2B JBrowse link 19 551,708 553,573 RGD:1624291
RGD:13792537
G Ciao3 cytosolic iron-sulfur assembly component 3 JBrowse link 10 15,143,732 15,152,706 RGD:1624291
RGD:13792537
RGD:1600115
G Ciapin1 cytokine induced apoptosis inhibitor 1 JBrowse link 19 10,596,923 10,612,414 RGD:13792537
G Fxn frataxin JBrowse link 1 242,123,975 242,152,834 RGD:1600115
RGD:1624291
G Hscb HscB mitochondrial iron-sulfur cluster co-chaperone JBrowse link 12 51,878,267 51,888,645 RGD:1624291
G Hspa9 heat shock protein family A (Hsp70) member 9 JBrowse link 18 27,731,072 27,749,235 RGD:1600115
RGD:1624291
G Iba57 iron-sulfur cluster assembly factor IBA57 JBrowse link 10 45,506,124 45,514,909 RGD:13792537
G Isca1 iron-sulfur cluster assembly 1 JBrowse link 17 5,281,727 5,294,386 RGD:13792537
G Isca2 iron-sulfur cluster assembly 2 JBrowse link 6 108,488,678 108,490,188 RGD:13792537
G Iscu iron-sulfur cluster assembly enzyme JBrowse link 12 48,621,454 48,627,297 RGD:1600115
G Lyrm4 LYR motif containing 4 JBrowse link 17 29,439,042 29,552,773 RGD:13792537
G Mms19 MMS19 homolog, cytosolic iron-sulfur assembly component JBrowse link 1 261,191,646 261,229,070 RGD:1624291
RGD:13792537
G Ndor1 NADPH dependent diflavin oxidoreductase 1 JBrowse link 3 2,466,698 2,474,928 RGD:1600115
G Nfs1 NFS1 cysteine desulfurase JBrowse link 3 151,665,813 151,688,151 RGD:13792537
G Nfu1 NFU1 iron-sulfur cluster scaffold JBrowse link 4 118,814,284 118,834,955 RGD:1624291
RGD:13792537
G Nubp1 nucleotide binding protein 1 JBrowse link 10 5,333,378 5,343,949 RGD:1624291
RGD:13792537
RGD:1600115
G Nubp2 nucleotide binding protein 2 JBrowse link 10 14,244,201 14,247,930 RGD:13792537
G Nubpl nucleotide binding protein-like JBrowse link 6 72,891,758 73,147,837 RGD:13792537
G Tst thiosulfate sulfurtransferase JBrowse link 7 119,616,323 119,623,072 RGD:729953
[2Fe-2S] cluster assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bola2 bolA family member 2 JBrowse link 1 198,120,104 198,121,158 RGD:1624291
RGD:13792537
G Glrx3 glutaredoxin 3 JBrowse link 1 209,768,696 209,799,912 RGD:1624291
RGD:1600115
G Hscb HscB mitochondrial iron-sulfur cluster co-chaperone JBrowse link 12 51,878,267 51,888,645 RGD:13792537
G Nfs1 NFS1 cysteine desulfurase JBrowse link 3 151,665,813 151,688,151 RGD:1600115
iron incorporation into metallo-sulfur cluster term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fxn frataxin JBrowse link 1 242,123,975 242,152,834 RGD:1624291
RGD:1600115
RGD:13792537
G Nfs1 NFS1 cysteine desulfurase JBrowse link 3 151,665,813 151,688,151 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    metabolic process 11954
      cellular metabolic process 10782
        sulfur compound metabolic process 298
          iron-sulfur cluster assembly 23
            [2Fe-2S] cluster assembly + 4
            [4Fe-4S] cluster assembly + 0
            iron incorporation into metallo-sulfur cluster + 2
            iron-sulfur-molybdenum cofactor assembly + 0
            molybdenum incorporation into iron-sulfur cluster + 0
            negative regulation of iron-sulfur cluster assembly + 0
            nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide + 0
            nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide 0
            nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide 0
            nitrogenase P cluster assembly 0
            positive regulation of iron-sulfur cluster assembly + 0
            regulation of iron-sulfur cluster assembly + 0
Path 2
Term Annotations click to browse term
  biological_process 19678
    cellular process 18452
      cellular component organization or biogenesis 6667
        cellular component organization 6427
          cellular component assembly 2942
            metallo-sulfur cluster assembly 23
              iron-sulfur cluster assembly 23
                [2Fe-2S] cluster assembly + 4
                [4Fe-4S] cluster assembly + 0
                iron incorporation into metallo-sulfur cluster + 2
                iron-sulfur-molybdenum cofactor assembly + 0
                molybdenum incorporation into iron-sulfur cluster + 0
                negative regulation of iron-sulfur cluster assembly + 0
                nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide + 0
                nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide 0
                nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide 0
                nitrogenase P cluster assembly 0
                positive regulation of iron-sulfur cluster assembly + 0
                regulation of iron-sulfur cluster assembly + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.