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ONTOLOGY REPORT - ANNOTATIONS

Term:sterol biosynthetic process
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Accession:GO:0016126 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
Synonyms:exact_synonym: sterol anabolism;   sterol biosynthesis;   sterol formation;   sterol synthesis
 xref: MetaCyc:PWY-2541


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sterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458 		JBrowse link
G Cyb5r2 cytochrome b5 reductase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:161,655,862...161,664,359
Ensembl chr 1:161,655,864...161,664,097 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase acts_upstream_of_or_within ISO MGI:2387406 (PMID:15005800) RGD PMID:15005800 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase acts_upstream_of_or_within TAS
ISO		 MGI:1857832 (PMID:10391218) RGD PMID:10391218 PMID:11171067 RGD:628445 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Faxdc2 fatty acid hydroxylase domain containing 2 involved_in IEA
IBA		 GO_REF:0000043
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000043 NCBI chr10:42,245,808...42,271,679
Ensembl chr10:42,246,868...42,271,871 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO MGI:1920249 (PMID:16955138) RGD PMID:16955138 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO MGI:1916289 (PMID:16955138) RGD PMID:16955138 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
G Pmvk phosphomevalonate kinase involved_in ISO (PMID:16519518) RGD PMID:16519518 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364 		JBrowse link
G Sqle squalene epoxidase involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000104
GO_REF:0000033
(PMID:30626872)		 UniProt
GO_Central
RGD		 PMID:30626872 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07021955.1 involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041
G Acat2 acetyl-CoA acetyltransferase 2 involved_in TAS PMID:10806397 UniProt PMID:10806397 RGD:2326086 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Apoa1 apolipoprotein A1 acts_upstream_of_or_within ISO MGI:2180783 (PMID:8647961) RGD PMID:8647961 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:11015575) RGD PMID:11015575 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cftr CF transmembrane conductance regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856709 (PMID:17085523)		 Ensembl
RGD		 PMID:17085523 GO_REF:0000107 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:14684813)
MGI:3027024 (PMID:14684813), (PMID:16321981), (PMID:16513830)
(PMID:11519011)		 UniProt
RGD		 PMID:11519011 PMID:14684813 PMID:16321981 PMID:16513830 GO_REF:0000024 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase involved_in TAS
IBA
IEA
ISO
IMP
IC
IDA		 GO_REF:0000033
GO_REF:0000041
(PMID:9465114)		 GO_Central
UniProt
RGD		 PMID:9465114 PMID:12031495 PMID:9831636 PMID:10666310 PMID:10329655 GO_REF:0000033 GO_REF:0000041, RGD:625561, RGD:2316918, RGD:2316916, RGD:632010 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase involved_in IDA
IBA
ISO
IEA
TAS		 GO_REF:0000033
(PMID:9894009)
GO_REF:0000041		 GO_Central
RGD
UniProt		 PMID:9894009 PMID:11171067 PMID:11171067 GO_REF:0000033 GO_REF:0000041, RGD:628445, RGD:628445 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G ENSRNOG00000062441 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr17:61,602,519...61,608,185 JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16440058 GO_REF:0000033, RGD:1626611 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fdps farnesyl diphosphate synthase TAS RGD PMID:1321149 RGD:728501 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (PMID:12027950) RGD PMID:12027950 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:23063590)
(PMID:15845870), (PMID:7798939), (PMID:8647961)
GO_REF:0000107
GO_REF:0000043		 RGD
Ensembl
UniProt		 PMID:7798939 PMID:8647961 PMID:15845870 PMID:23063590 GO_REF:0000043 GO_REF:0000107 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 involved_in
acts_upstream_of_or_within		 ISO
IBA
ISS
IEA		 (PMID:12829805)
GO_REF:0000033
GO_REF:0000024
GO_REF:0000107		 RGD
GO_Central
UniProt
Ensembl		 PMID:12829805 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 involved_in TAS
IEA		 GO_REF:0000043 UniProt
RGD		 PMID:9228075 GO_REF:0000043, RGD:729078 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,331,385...61,334,987
Ensembl chr17:61,331,669...61,334,285 		JBrowse link
G Idi2-ps1 isopentenyl-diphosphate delta isomerase 2, pseudogene 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,420,357...61,423,924 JBrowse link
G Idi2l2 isopentenyl-diphosphate delta isomerase 2 like 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,372,853...61,386,459
Ensembl chr17:61,373,678...61,386,454 		JBrowse link
G Idi2l3 isopentenyl-diphosphate delta isomerase 2 like 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,518,138...61,535,484
Ensembl chr17:61,519,390...61,531,603 		JBrowse link
G Insig1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:32322062)
MGI:1920249 (PMID:16955138)
GO_REF:0000033		 RGD
GO_Central		 PMID:16955138 PMID:32322062 GO_REF:0000033 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insig2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 GO_REF:0000024
MGI:1916289 (PMID:16955138)
GO_REF:0000033
GO_REF:0000107
(PMID:32322062)		 UniProt
RGD
GO_Central
Ensembl		 PMID:16955138 PMID:32322062 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Lbr lamin B receptor involved_in ISO
IBA
IEA
ISS		 (PMID:16784888), (PMID:27336722)
GO_REF:0000033
(MGI:3822946|PMID:18785926), (MGI:5308142|PMID:22140257)
GO_REF:0000041
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:16784888 PMID:18785926 PMID:22140257 PMID:27336722 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 MGI:3822946 MGI:5308142 NCBI chr13:93,539,386...93,564,026
Ensembl chr13:93,538,920...93,564,017 		JBrowse link
G Lipa lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2451080 (PMID:25147230), (PMID:29599133)		 Ensembl
RGD		 PMID:25147230 PMID:29599133 GO_REF:0000107 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G LOC102550988 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,451,920...61,457,799
Ensembl chr17:61,451,918...61,458,215 		JBrowse link
G LOC102551575 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,504,294...61,507,015
Ensembl chr17:61,504,535...61,507,015 		JBrowse link
G LOC120097764 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,338,622...61,349,795
Ensembl chr17:61,347,251...61,349,795
Ensembl chr17:61,347,251...61,349,795 		JBrowse link
G LOC120102490 insulin-induced gene 1 protein-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:67,330,399...67,331,371
Ensembl chr 4:67,330,588...67,331,346 		JBrowse link
G LOC134482631 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482634 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482635 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482779 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482866 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134484812 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G Lss lanosterol synthase involved_in IMP
IBA
IEA
IDA
ISO		 GO_REF:0000033
GO_REF:0000107
PMID:7568116
(PMID:17186944)		 GO_Central
Ensembl
RGD		 PMID:17186944 PMID:16440058 PMID:7568116 PMID:1429550 GO_REF:0000033 GO_REF:0000107, RGD:1626611, RGD:728996, RGD:2316919 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase involved_in NAS
IEA		 GO_REF:0000041 UniProt
RGD		 PMID:11767099 GO_REF:0000041, RGD:729305 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971 		JBrowse link
G Mvk mevalonate kinase involved_in TAS
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
GO_REF:0000043
(PMID:1377680)		 GO_Central
Ensembl
UniProt
RGD		 PMID:1377680 PMID:2158094 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:728935 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882 		JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO (PMID:17140581) RGD PMID:17140581 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113 		JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142 		JBrowse link
G Pmvk phosphomevalonate kinase involved_in ISO
IBA
NAS		 (PMID:8663599)
GO_REF:0000033
PMID:10191291		 RGD
GO_Central		 PMID:8663599 PMID:10191291 GO_REF:0000033, RGD:8553625 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of ISO MGI:2177958 (PMID:9329978) RGD PMID:9329978 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 involved_in IEA
ISO
IBA		 GO_REF:0000041
(PMID:18785926)
GO_REF:0000033
(MGI:3822946|PMID:18785926)
(PMID:16784888)		 UniProt
RGD
GO_Central		 PMID:16784888 PMID:18785926 GO_REF:0000033 GO_REF:0000041 MGI:3822946 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270 		JBrowse link
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 IDA RGD PMID:7581240 RGD:2316902 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
cholesterol biosynthetic process via desmosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr24 24-dehydrocholesterol reductase involved_in ISO (PMID:11519011) RGD PMID:11519011 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr7 7-dehydrocholesterol reductase involved_in ISO
IEA		 (PMID:38297129), (PMID:38297130)
GO_REF:0000107		 RGD
Ensembl		 PMID:38297129 PMID:38297130 GO_REF:0000107 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Sc5d sterol-C5-desaturase involved_in IDA
ISO
IBA		 PMID:4019441
(PMID:10786622)
GO_REF:0000033		 RGD
GO_Central		 PMID:10786622 PMID:7961720 PMID:4019441 GO_REF:0000033, RGD:2316911, RGD:405866208 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
IEA
ISO		 GO_REF:0000107
(PMID:1917954)		 Ensembl
RGD		 PMID:1917954 PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G C12h7orf50 similar to human chromosome 7 open reading frame 50 involved_in ISO (PMID:38503280) RGD PMID:38503280 NCBI chr12:15,185,728...15,289,042
Ensembl chr12:15,185,707...15,289,069 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671 		JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) RGD PMID:17202134 NCBI chr17:61,331,385...61,334,987
Ensembl chr17:61,331,669...61,334,285 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:23951060), (PMID:24296663) RGD PMID:23951060 PMID:24296663 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir342 microRNA 342 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367 		JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:30195495) RGD PMID:30195495 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3768186|PMID:17916878)
(PMID:17916878)		 RGD PMID:17916878 MGI:3768186 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 involved_in ISO
IEA		 (MGI:3768186|PMID:17916878)
GO_REF:0000107
(PMID:17916878)		 RGD
Ensembl		 PMID:17916878 GO_REF:0000107 MGI:3768186 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:18637708 RGD:2316295 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19229075)		 UniProt
RGD		 PMID:19229075 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Gnai1 G protein subunit alpha i1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:38503280)		 Ensembl
RGD		 PMID:38503280 GO_REF:0000107 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:38503280)		 Ensembl
RGD		 PMID:38503280 GO_REF:0000107 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mir96 microRNA 96 involved_in
acts_upstream_of		 ISO RNAcentral:URS00001CC379_9606 (PMID:23823476)
(PMID:30460077)		 RGD PMID:23823476 PMID:30460077 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 IMP RGD PMID:32976883 RGD:405096663 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:38503280)		 Ensembl
RGD		 PMID:38503280 GO_REF:0000107 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (MGI:6712091|PMID:33942715) RGD PMID:33942715 MGI:6712091 NCBI chr 1:50,387,716...50,501,568
Ensembl chr 1:50,387,698...50,498,831 		JBrowse link
G Scap SREBF chaperone involved_in ISO (PMID:32322062) RGD PMID:32322062 NCBI chr 8:110,306,026...110,360,677
Ensembl chr 8:110,306,031...110,360,666 		JBrowse link
G Scp2 sterol carrier protein 2 IDA RGD PMID:2554812 RGD:9850260 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 IDA RGD PMID:11226224 RGD:727312 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (MGI:3623165|PMID:9062341), (MGI:83216|PMID:8833906)
(PMID:12177166)
(PMID:32322062)
GO_REF:0000024
MGI:2177958|MGI:2177959 (PMID:16046411), (PMID:9329978)		 RGD
UniProt		 PMID:8833906 PMID:9062341 PMID:9329978 PMID:12177166 PMID:16046411 More... GO_REF:0000024 MGI:3623165 MGI:83216 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:32322062)
GO_REF:0000024
(MGI:6712091|PMID:33942715), (MGI:6713934|PMID:34021134)
(PMID:12177166), (PMID:38503280)		 Ensembl
RGD
UniProt		 PMID:12177166 PMID:32322062 PMID:33942715 PMID:34021134 PMID:38503280 GO_REF:0000024 GO_REF:0000107 MGI:6712091 MGI:6713934 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Apob apolipoprotein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2183298 (PMID:16455790)		 Ensembl
RGD		 PMID:16455790 GO_REF:0000107 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Aqp8 aquaporin 8 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:30579780)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:30579780 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158 		JBrowse link
G Cyp51 cytochrome P450, family 51 TAS RGD PMID:7665087 RGD:1298863 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase IDA RGD PMID:10329655 RGD:632010 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671 		JBrowse link
G Gpr146 G protein-coupled receptor 146 involved_in IEA
ISO		 GO_REF:0000107
(PMID:38503280)		 Ensembl
RGD		 PMID:38503280 GO_REF:0000107 NCBI chr12:15,251,936...15,267,217
Ensembl chr12:15,251,813...15,267,206 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29395055)
(MGI:6278041|PMID:29395055)		 UniProt
RGD		 PMID:29395055 GO_REF:0000024 MGI:6278041 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880 		JBrowse link
G Mvk mevalonate kinase NAS RGD PMID:2158094 RGD:728935 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882 		JBrowse link
G Pex2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO MGI:2180128 (PMID:14673138) RGD PMID:14673138 NCBI chr 2:96,050,380...96,072,928
Ensembl chr 2:96,045,958...96,073,404 		JBrowse link
G Scap SREBF chaperone involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2148743|MGI:2180899 (PMID:16054043)		 GO_Central
RGD		 PMID:16054043 GO_REF:0000033 NCBI chr 8:110,306,026...110,360,677
Ensembl chr 8:110,306,031...110,360,666 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20133
    cellular process 19325
      metabolic process 12307
        biosynthetic process 8434
          organic hydroxy compound biosynthetic process 270
            sterol biosynthetic process 82
              cholesterol biosynthetic process + 77
              ecdysone biosynthetic process 0
              ergosterol biosynthetic process + 0
              negative regulation of sterol biosynthetic process + 8
              positive regulation of sterol biosynthetic process + 17
              regulation of sterol biosynthetic process + 34
              zymosterol biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 20133
    cellular process 19325
      metabolic process 12307
        primary metabolic process 10934
          lipid metabolic process 1457
            steroid metabolic process 370
              steroid biosynthetic process 198
                sterol biosynthetic process 82
                  cholesterol biosynthetic process + 77
                  ecdysone biosynthetic process 0
                  ergosterol biosynthetic process + 0
                  negative regulation of sterol biosynthetic process + 8
                  positive regulation of sterol biosynthetic process + 17
                  regulation of sterol biosynthetic process + 34
                  zymosterol biosynthetic process 0
paths to the root