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ONTOLOGY REPORT - ANNOTATIONS


Term:sterol metabolic process
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Accession:GO:0016125 term browser browse the term
Definition:The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
Synonyms:exact_synonym: sterol metabolism


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sterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arv1 ARV1 homolog, fatty acid homeostasis modulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:57,484,720...57,496,539
Ensembl chr19:57,484,634...57,496,695
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:256,369,410...256,380,649
Ensembl chr 1:256,370,850...256,378,335
JBrowse link
G Cyp51 cytochrome P450, family 51 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase acts_upstream_of_or_within ISO MGI:3027024 (MGI:2686848|PMID:14684813) RGD PMID:14684813 MGI:2686848 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Ebpl EBP like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:41,668,119...41,691,518
Ensembl chr15:41,668,119...41,691,518
JBrowse link
G Lipa lipase A, lysosomal acid type involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:10419291, PMID:21873635 RGD:1626385, RGD:13792537 NCBI chr 1:252,816,536...252,959,348
Ensembl chr 1:252,816,527...252,849,904
JBrowse link
G Lss lanosterol synthase IMP RGD PMID:16440058 RGD:1626611 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
JBrowse link
G Mvk mevalonate kinase TAS RGD PMID:11877411 RGD:729101 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400
JBrowse link
cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07021955.1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 Ensembl chr13:100,431,390...100,450,209 JBrowse link
G AABR07028137.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr17:57,755,210...57,765,652 JBrowse link
G AABR07028157.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr17:57,906,050...57,908,621 JBrowse link
G AABR07060293.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 4:66,336,143...66,336,901 JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 involved_in TAS PMID:10806397 UniProt PMID:10806397 RGD:2326086 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Apoa1 apolipoprotein A1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2180783 (MGI:2180727|PMID:8647961)
RGD PMID:8647961, PMID:21873635 MGI:2180727, RGD:13792537 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa4 apolipoprotein A4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoa5 apolipoprotein A5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:11015575) RGD PMID:11015575 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cftr CF transmembrane conductance regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856709 (MGI:3709533|PMID:17085523)
Ensembl
RGD
PMID:17085523 GO_REF:0000107 MGI:3709533 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:124,024,003...124,041,564
Ensembl chr 7:124,023,995...124,041,594
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:11519011)
MGI:3027024 (MGI:2686848|PMID:14684813), (MGI:3624168|PMID:16321981), (MGI:3769949|PMID:16513830)
UniProt
RGD
PMID:11519011 PMID:14684813 PMID:16321981 PMID:16513830 GO_REF:0000024 MGI:2686848 MGI:3624168 MGI:3769949 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase involved_in TAS
IBA
IEA
ISO
IMP
IC
IDA
PMID:21873635
GO_REF:0000041
(PMID:9465114)
UniProt
RGD
PMID:9465114, PMID:12031495, PMID:21873635, PMID:9831636, PMID:10666310, PMID:10329655 GO_REF:0000041, RGD:625561, RGD:13792537, RGD:2316918, RGD:2316916, RGD:632010 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Ebp EBP, cholestenol delta-isomerase involved_in IDA
ISO
IBA
IEA
TAS
(PMID:9894009)
PMID:21873635
GO_REF:0000041
RGD
UniProt
PMID:9894009, PMID:11171067, PMID:21873635, PMID:11171067 GO_REF:0000041, RGD:628445, RGD:13792537, RGD:628445 NCBI chr  X:15,049,394...15,055,782
Ensembl chr  X:15,049,462...15,055,781
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 involved_in TAS
IBA
IMP
PMID:21873635 RGD
GO_Central
PMID:1400448, PMID:21873635, PMID:16440058 RGD:728402, RGD:13792537, RGD:1626611 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase TAS RGD PMID:1321149 RGD:728501 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (PMID:12027950) RGD PMID:12027950 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase involved_in
acts_upstream_of_or_within
ISO (PMID:23063590)
(MGI:2180727|PMID:8647961), (MGI:3603484|PMID:15845870), (MGI:70238|PMID:7798939)
RGD PMID:7798939 PMID:8647961 PMID:15845870 PMID:23063590 MGI:2180727 MGI:3603484 MGI:70238 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 involved_in
acts_upstream_of_or_within
ISO
IBA
ISS
IEA
(PMID:12829805)
(MGI:2673751|PMID:12829805)
PMID:21873635
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:12829805, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:2673751, RGD:13792537 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 involved_in TAS
IEA
GO_REF:0000043 UniProt PMID:9228075 GO_REF:0000043, RGD:729078 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Insig1 insulin induced gene 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1920249 (MGI:3689278|PMID:16955138)
(PMID:32322062)
RGD PMID:16955138 PMID:32322062, PMID:21873635 MGI:3689278, RGD:13792537 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insig2 insulin induced gene 2 involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
GO_REF:0000024
MGI:1916289 (MGI:3689278|PMID:16955138)
PMID:21873635
(PMID:32322062)
UniProt
RGD
PMID:16955138 PMID:32322062, PMID:21873635 GO_REF:0000024 MGI:3689278, RGD:13792537 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Lbr lamin B receptor involved_in ISO
IEA
ISS
(PMID:16784888), (PMID:27336722)
(MGI:3822946|PMID:18785926), (MGI:5308142|PMID:22140257)
GO_REF:0000041
GO_REF:0000024
RGD
UniProt
PMID:16784888 PMID:18785926 PMID:22140257 PMID:27336722 GO_REF:0000024 GO_REF:0000041 MGI:3822946 MGI:5308142 NCBI chr13:100,431,390...100,450,209 JBrowse link
G LOC102551575 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:57,864,652...57,866,201
Ensembl chr17:57,864,244...57,865,804
JBrowse link
G LOC103694120 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:57,814,239...57,816,277
Ensembl chr17:57,814,539...57,816,256
JBrowse link
G LOC291276 similar to isopentenyl diphosphate delta-isomerase type 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:57,701,861...57,705,698
Ensembl chr17:57,701,861...57,704,293
JBrowse link
G Lss lanosterol synthase involved_in IMP
IDA
IBA
ISO
IEA
PMID:7568116
PMID:21873635
(PMID:17186944)
GO_REF:0000107
RGD
Ensembl
PMID:17186944, PMID:16440058, PMID:7568116, PMID:21873635, PMID:1429550 GO_REF:0000107, RGD:1626611, RGD:728996, RGD:13792537, RGD:2316919 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
JBrowse link
G Msmo1 methylsterol monooxygenase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link
G Mvd mevalonate diphosphate decarboxylase involved_in NAS
IEA
GO_REF:0000041 UniProt PMID:11767099 GO_REF:0000041, RGD:729305 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951
JBrowse link
G Mvk mevalonate kinase involved_in TAS
IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:1377680)
Ensembl
RGD
PMID:1377680, PMID:2158094, PMID:21873635 GO_REF:0000107, RGD:728935, RGD:13792537 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO (PMID:17140581) RGD PMID:17140581 NCBI chr14:86,345,946...86,560,694
Ensembl chr14:86,345,953...86,560,694
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:152,933,118...152,964,399
Ensembl chr  X:152,933,069...152,964,390
JBrowse link
G Pmvk phosphomevalonate kinase involved_in IBA
NAS
ISO
PMID:21873635
PMID:10191291
(PMID:8663599)
RGD PMID:8663599, PMID:21873635, PMID:10191291 RGD:13792537, RGD:8553625 NCBI chr 2:188,784,329...188,793,890
Ensembl chr 2:188,784,222...188,793,895
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:124,568,845...124,642,569
Ensembl chr 5:124,574,079...124,642,569
JBrowse link
G RGD1564347 similar to isopentenyl diphosphate delta-isomerase type 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:57,674,146...57,688,350
Ensembl chr17:57,676,569...57,687,379
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 involved_in IEA
ISO
IDA
GO_REF:0000041
(MGI:3822946|PMID:18785926)
PMID:16784888
(PMID:16784888)
UniProt
RGD
PMID:16784888 PMID:18785926, PMID:16784888 GO_REF:0000041 MGI:3822946, RGD:13825441 NCBI chr 1:221,426,017...221,430,340
Ensembl chr 1:221,425,987...221,431,713
JBrowse link
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 IDA RGD PMID:7581240 RGD:2316902 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
cholesterol biosynthetic process via desmosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr24 24-dehydrocholesterol reductase involved_in ISO (PMID:11519011) RGD PMID:11519011 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sc5d sterol-C5-desaturase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7961720, PMID:21873635 RGD:2316911, RGD:13792537 NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050
JBrowse link
cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1d1 aldo-keto reductase family 1, member D1 involved_in ISO
IEA
(PMID:7508385)
GO_REF:0000107
RGD
Ensembl
PMID:7508385 GO_REF:0000107 NCBI chr 4:65,110,706...65,143,930
Ensembl chr 4:65,110,746...65,143,941
JBrowse link
G Apoe apolipoprotein E involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1314982|PMID:9826706)
RGD PMID:9826706, PMID:21873635 MGI:1314982, RGD:13792537 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Cel carboxyl ester lipase involved_in ISO
IEA
(PMID:12031288)
GO_REF:0000107
RGD
Ensembl
PMID:12031288 GO_REF:0000107 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
GO_REF:0000041
(PMID:9660774)
UniProt
Ensembl
RGD
PMID:9660774 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO (MGI:1859119|PMID:10748047) RGD PMID:10748047 MGI:1859119 NCBI chr 9:19,804,079...19,880,346
Ensembl chr 9:19,804,079...19,880,346
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in IBA
ISO
PMID:21873635
(MGI:1339884|PMID:10377398), (MGI:6393037|PMID:20193040)
(PMID:14640697), (PMID:18621681), (PMID:25017465)
RGD PMID:10377398 PMID:14640697 PMID:18621681 PMID:20193040 PMID:25017465, PMID:21873635 MGI:1339884 MGI:6393037, RGD:13792537 NCBI chr 6:132,242,328...132,273,788
Ensembl chr 6:132,242,328...132,273,787
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in
acts_upstream_of_or_within
IDA
ISO
IEA
PMID:1694852
(MGI:1933035|PMID:11279518), (MGI:3603484|PMID:15845870)
GO_REF:0000041
RGD
UniProt
PMID:11279518 PMID:15845870, PMID:1694852 GO_REF:0000041 MGI:1933035 MGI:3603484, RGD:70534 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 IDA RGD PMID:16081591 RGD:1599972 NCBI chr 1:199,248,084...199,251,745
Ensembl chr 1:199,248,470...199,251,740
JBrowse link
G Mt3 metallothionein 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:4881636|PMID:20544854)
UniProt
RGD
PMID:20544854 GO_REF:0000024 MGI:4881636 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Scarb1 scavenger receptor class B, member 1 acts_upstream_of_or_within ISO MGI:1928989 (MGI:1934548|PMID:11278646), (MGI:3690692|PMID:10559220) RGD PMID:10559220 PMID:11278646 MGI:1934548 MGI:3690692 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in
acts_upstream_of_or_within
ISO (PMID:14747463)
(MGI:2153573|PMID:11559713)
RGD PMID:11559713 PMID:14747463 MGI:2153573 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:25125465)
UniProt
Ensembl
RGD
PMID:25125465 GO_REF:0000024 GO_REF:0000107 NCBI chr10:98,573,226...98,645,028
Ensembl chr10:98,576,039...98,644,938
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:15994327) RGD PMID:15994327 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Angptl3 angiopoietin-like 3 involved_in ISO (PMID:17110602) RGD PMID:17110602 NCBI chr 5:117,698,590...117,706,729
Ensembl chr 5:117,698,764...117,705,808
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 acts_upstream_of_or_within ISO MGI:88059 (MGI:3762423|PMID:17920016) RGD PMID:17920016 MGI:3762423 NCBI chr 8:32,298,526...32,328,821
Ensembl chr 8:32,298,532...32,328,839
JBrowse link
G Apoa1 apolipoprotein A1 involved_in
acts_upstream_of_or_within
ISO (PMID:15464323)
MGI:104663|MGI:104993|MGI:1857127 (MGI:1099137|PMID:9327769), (MGI:1339278|PMID:10357841), (MGI:3487338|PMID:15466405), (MGI:3588626|PMID:15995171), (MGI:3688492|PMID:9795222), (MGI:3696597|PMID:17071966), (MGI:70854|PMID:7751823)
RGD PMID:7751823 PMID:9327769 PMID:9795222 PMID:10357841 PMID:15464323 PMID:15466405 PMID:15995171 PMID:17071966 MGI:1099137 MGI:1339278 MGI:3487338 MGI:3588626 MGI:3688492 MGI:3696597 MGI:70854 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa2 apolipoprotein A2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2157148|MGI:96216 (MGI:1339279|PMID:10357838), (MGI:2180727|PMID:8647961)
RGD PMID:8647961 PMID:10357838, PMID:21873635 MGI:1339279 MGI:2180727, RGD:13792537 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apoa4 apolipoprotein A4 involved_in IEA
ISO
GO_REF:0000107
(PMID:1935934)
Ensembl
RGD
PMID:1935934 GO_REF:0000107 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apob apolipoprotein B involved_in ISO (PMID:2563166) RGD PMID:2563166 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc1 apolipoprotein C1 acts_upstream_of_or_within ISO MGI:2157218 (MGI:70746|PMID:7848292) RGD PMID:7848292 MGI:70746 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoc3 apolipoprotein C3 acts_upstream_of_or_within ISO MGI:1857128|MGI:3758464 (MGI:2152463|PMID:11590213), (MGI:69667|PMID:8089130), (MGI:82330|PMID:8864964) RGD PMID:8089130 PMID:8864964 PMID:11590213 MGI:2152463 MGI:69667 MGI:82330 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Apoe apolipoprotein E involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2137814 (MGI:2180727|PMID:8647961), (MGI:51330|PMID:1423598)
(PMID:3771793), (PMID:9649566)
Ensembl
RGD
PMID:1423598 PMID:3771793 PMID:8647961 PMID:9649566 GO_REF:0000107 MGI:2180727 MGI:51330 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apof apolipoprotein F involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3800154 (MGI:5428098|PMID:22363685)
RGD PMID:22363685, PMID:21873635 MGI:5428098, RGD:13792537 NCBI chr 7:2,689,501...2,690,938
Ensembl chr 7:2,689,501...2,690,936
JBrowse link
G Apon apolipoprotein N involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:2,675,796...2,677,199
Ensembl chr 7:2,675,797...2,677,199
JBrowse link
G App amyloid beta precursor protein acts_upstream_of_or_within ISO MGI:2136847|MGI:88047 (MGI:3762423|PMID:17920016) RGD PMID:17920016 MGI:3762423 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Cat catalase acts_upstream_of_or_within ISO MGI:3053604 (MGI:53683|PMID:5087482) RGD PMID:5087482 MGI:53683 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3848341 (MGI:3847596|PMID:18974039)
Ensembl
RGD
PMID:18974039 GO_REF:0000107 MGI:3847596 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:16024911) RGD PMID:16024911 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ch25h cholesterol 25-hydroxylase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1316846|PMID:9852097)
RGD PMID:9852097, PMID:21873635 MGI:1316846, RGD:13792537 NCBI chr 1:252,807,062...252,811,409
Ensembl chr 1:252,807,065...252,808,380
JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO (PMID:16857350) RGD PMID:16857350 NCBI chr 8:67,733,215...67,748,170
Ensembl chr 8:67,733,215...67,748,172
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein involved_in ISS
ISO
GO_REF:0000024
(PMID:16086686)
UniProt
RGD
PMID:16086686 GO_REF:0000024 NCBI chr16:79,828,321...79,838,212
Ensembl chr16:79,828,324...79,838,212
JBrowse link
G Cubn cubilin involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:80,584,921...80,807,181
Ensembl chr17:80,584,878...80,807,243
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 involved_in IBA
ISO
ISS
IEA
PMID:21873635
(PMID:18182448), (PMID:21636783)
GO_REF:0000024
GO_REF:0000041
RGD
UniProt
PMID:18182448 PMID:21636783, PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:116,195,976...116,201,829 JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:2175615, PMID:21873635 RGD:1299597, RGD:13792537 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 TAS RGD PMID:12029625 RGD:1298868 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase acts_upstream_of_or_within ISO MGI:3027024 (MGI:3614236|PMID:16407971) RGD PMID:16407971 MGI:3614236 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:69,179,005...69,195,452
Ensembl chr16:69,179,588...69,195,097
JBrowse link
G Fdx1 ferredoxin 1 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:21636783)
Ensembl
UniProt
RGD
PMID:21636783 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:56,373,729...56,393,199
Ensembl chr 8:56,373,723...56,393,233
JBrowse link
G Fdxr ferredoxin reductase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1858114 (MGI:1930023|PMID:11160364) RGD PMID:11160364 MGI:1930023 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Fgl1 fibrinogen-like 1 acts_upstream_of_or_within ISO MGI:5510996 (MGI:5505372|PMID:23483972) RGD PMID:23483972 MGI:5505372 NCBI chr16:54,153,086...54,188,120
Ensembl chr16:54,153,054...54,188,181
JBrowse link
G Gba glucosylceramidase beta involved_in ISO
IEA
(PMID:24211208), (PMID:26724485)
(MGI:6271235|PMID:24211208)
GO_REF:0000041
RGD
UniProt
PMID:24211208 PMID:26724485 GO_REF:0000041 MGI:6271235 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in IEA
ISO
ISS
GO_REF:0000041
(MGI:5771619|PMID:26724485)
GO_REF:0000024
UniProt
RGD
PMID:26724485 GO_REF:0000024 GO_REF:0000041 MGI:5771619 NCBI chr 5:59,068,081...59,079,719
Ensembl chr 5:59,068,081...59,079,719
JBrowse link
G Hdlbp high density lipoprotein binding protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:100,554,574...100,624,707
Ensembl chr 9:100,554,563...100,624,638
JBrowse link
G Hnf1a HNF1 homeobox A acts_upstream_of_or_within ISO MGI:2384427 (MGI:1933035|PMID:11279518) RGD PMID:11279518 MGI:1933035 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 NAS RGD PMID:8913347 RGD:632889 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Il4 interleukin 4 involved_in ISO (MGI:2178917|PMID:11971948) RGD PMID:11971948 MGI:2178917 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO MGI:1920249 (MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:3603108 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO MGI:1916289 (MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:3603108 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Lcat lecithin cholesterol acyltransferase acts_upstream_of_or_within
involved_in
IDA
ISO
(PMID:10559507)
(PMID:26195816), (PMID:4335615)
(MGI:1096057|PMID:9300780)
RGD PMID:4335615 PMID:9300780 PMID:10559507 PMID:26195816, PMID:746355 MGI:1096057, RGD:1581789 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Ldlr low density lipoprotein receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857212 (MGI:3696597|PMID:17071966)
Ensembl
RGD
PMID:17071966 GO_REF:0000107 MGI:3696597 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211
JBrowse link
G Lep leptin acts_upstream_of_or_within ISO MGI:88049 (MGI:3588626|PMID:15995171) RGD PMID:15995171 MGI:3588626 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor acts_upstream_of_or_within ISO MGI:88049 (MGI:3588626|PMID:15995171) RGD PMID:15995171 MGI:3588626 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lima1 LIM domain and actin binding 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:141,428,113...141,528,447
Ensembl chr 7:141,428,063...141,528,397
JBrowse link
G Lipc lipase C, hepatic type involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:88050 (MGI:1339279|PMID:10357838)
Ensembl
RGD
PMID:10357838 GO_REF:0000107 MGI:1339279 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Lipe lipase E, hormone sensitive type involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727
JBrowse link
G Lrp1 LDL receptor related protein 1 acts_upstream_of_or_within ISO MGI:2177650|MGI:2180880 (MGI:3762423|PMID:17920016) RGD PMID:17920016 MGI:3762423 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO MGI:2448955 (MGI:2448205|PMID:12509515) RGD PMID:12509515 MGI:2448205 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094
JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr19:52,146,507...52,206,310
Ensembl chr19:52,146,808...52,206,310
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1857776 (MGI:1338572|PMID:10369263)
RGD PMID:10369263, PMID:21873635 MGI:1338572, RGD:13792537 NCBI chr  X:152,933,118...152,964,399
Ensembl chr  X:152,933,069...152,964,390
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 acts_upstream_of_or_within ISO (MGI:3710922|PMID:17242417) RGD PMID:17242417 MGI:3710922 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Pctp phosphatidylcholine transfer protein acts_upstream_of_or_within ISO MGI:2673156 (MGI:3603484|PMID:15845870) RGD PMID:15845870 MGI:3603484 NCBI chr10:77,491,445...77,537,268
Ensembl chr10:77,491,454...77,512,032
JBrowse link
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 involved_in ISO
ISS
(PMID:25035345)
GO_REF:0000024
RGD
UniProt
PMID:25035345 GO_REF:0000024 NCBI chr15:27,852,152...27,855,999
Ensembl chr15:27,852,154...27,855,999
JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:3614822 (MGI:5616959|PMID:25429154) RGD PMID:25429154 MGI:5616959 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Pon1 paraoxonase 1 acts_upstream_of_or_within ISO MGI:2148702 (MGI:1860864|PMID:9685159) RGD PMID:9685159 MGI:1860864 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Scap SREBF chaperone involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:1934968|PMID:11358865)
UniProt
RGD
PMID:11358865 GO_REF:0000024 MGI:1934968 NCBI chr 8:118,551,869...118,628,650
Ensembl chr 8:118,570,503...118,628,651
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 acts_upstream_of_or_within ISO (MGI:5320806|PMID:22383528) RGD PMID:22383528 MGI:5320806 NCBI chr 1:170,383,682...170,387,525
Ensembl chr 1:170,383,682...170,387,524
JBrowse link
G Soat1 sterol O-acyltransferase 1 acts_upstream_of_or_within
involved_in
TAS
ISO
ISS
IBA
IEA
(PMID:9756919)
(PMID:16647063), (PMID:8407899)
(MGI:3603484|PMID:15845870)
GO_REF:0000024
PMID:21873635
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:8407899 PMID:9756919 PMID:15845870 PMID:16647063, PMID:9555010, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:3603484, RGD:730254, RGD:13792537 NCBI chr13:74,035,258...74,077,759
Ensembl chr13:74,035,080...74,077,783
JBrowse link
G Soat2 sterol O-acyltransferase 2 acts_upstream_of_or_within
involved_in
IDA
ISO
IEA
IBA
(MGI:1206070|PMID:9756919)
GO_REF:0000107
PMID:21873635
(PMID:11294643), (PMID:16647063)
RGD
Ensembl
PMID:9756919 PMID:11294643 PMID:16647063, PMID:12217884, PMID:21873635 GO_REF:0000107 MGI:1206070, RGD:625687, RGD:13792537 NCBI chr 7:143,754,892...143,767,989
Ensembl chr 7:143,754,892...143,767,989
JBrowse link
G Sqle squalene epoxidase involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:9300786, PMID:21873635 RGD:1625701, RGD:13792537 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 IMP RGD PMID:18071061 RGD:1643359 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srebf1_v2 sterol regulatory element binding factor 1, variant 2 IMP RGD PMID:18071061 RGD:1643359
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
G Star steroidogenic acute regulatory protein involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 involved_in ISO (PMID:28992322) RGD PMID:28992322 NCBI chr 9:4,931,038...4,978,847
Ensembl chr 9:4,930,818...4,978,892
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19589875)
UniProt
RGD
PMID:19589875 GO_REF:0000024 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 involved_in ISO
ISS
(PMID:28575648)
GO_REF:0000024
RGD
UniProt
PMID:28575648 GO_REF:0000024 NCBI chr 1:101,712,254...101,774,683
Ensembl chr 1:101,710,959...101,773,508
JBrowse link
G Tnfsf4 TNF superfamily member 4 acts_upstream_of_or_within ISO (MGI:57200|PMID:3473481) RGD PMID:3473481 MGI:57200 NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6407480|PMID:31391339)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:31391339 GO_REF:0000024 GO_REF:0000107 MGI:6407480 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591
JBrowse link
G Vldlr very low density lipoprotein receptor involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
ISO
IEA
(PMID:1917954)
GO_REF:0000107
RGD
Ensembl
PMID:1917954, PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:263,810,439...263,845,762
Ensembl chr 1:263,810,439...263,845,762
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:69,179,005...69,195,452
Ensembl chr16:69,179,588...69,195,097
JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (MGI:5490819|PMID:17202134) RGD PMID:17202134 MGI:5490819 NCBI chr17:63,107,152...63,107,469 JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:15473258)
UniProt
RGD
PMID:15473258 GO_REF:0000024 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3768186|PMID:17916878) RGD PMID:17916878 MGI:3768186 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:18637708 RGD:2316295 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19229075)
UniProt
RGD
PMID:19229075 GO_REF:0000024 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Scap SREBF chaperone involved_in ISO (PMID:32322062) RGD PMID:32322062 NCBI chr 8:118,551,869...118,628,650
Ensembl chr 8:118,570,503...118,628,651
JBrowse link
G Scp2 sterol carrier protein 2 IDA RGD PMID:2554812 RGD:9850260 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 IDA RGD PMID:11226224 RGD:727312 NCBI chr14:84,335,594...84,360,354
Ensembl chr14:84,335,597...84,355,528
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:32322062)
(MGI:3623165|PMID:9062341), (MGI:83216|PMID:8833906)
MGI:2177958|MGI:2177959 (MGI:1098057|PMID:9329978), (MGI:3603730|PMID:16046411)
GO_REF:0000024
RGD
UniProt
PMID:8833906 PMID:9062341 PMID:9329978 PMID:16046411 PMID:32322062 GO_REF:0000024 MGI:1098057 MGI:3603730 MGI:3623165 MGI:83216 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:32322062)
UniProt
RGD
PMID:32322062 GO_REF:0000024 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
positive regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D involved_in ISO (PMID:16971496) RGD PMID:16971496 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Apob apolipoprotein B acts_upstream_of_or_within ISO MGI:2183298 (MGI:3652707|PMID:16455790) RGD PMID:16455790 MGI:3652707 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Cyp51 cytochrome P450, family 51 TAS RGD PMID:7665087 RGD:1298863 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase IDA RGD PMID:10329655 RGD:632010 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:6278041|PMID:29395055)
UniProt
RGD
PMID:29395055 GO_REF:0000024 MGI:6278041 NCBI chr 4:157,181,722...157,222,997
Ensembl chr 4:157,181,795...157,222,996
JBrowse link
G Mvk mevalonate kinase NAS RGD PMID:2158094 RGD:728935 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO MGI:2180128 (MGI:3027293|PMID:14673138) RGD PMID:14673138 MGI:3027293 NCBI chr 2:98,251,756...98,269,185
Ensembl chr 2:98,252,925...98,269,184
JBrowse link
G Scap SREBF chaperone acts_upstream_of_or_within ISO MGI:2148743|MGI:2180899 (MGI:3770209|PMID:16054043) RGD PMID:16054043 MGI:3770209 NCBI chr 8:118,551,869...118,628,650
Ensembl chr 8:118,570,503...118,628,651
JBrowse link
regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:3526480 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO
GO_REF:0000107
(MGI:3526480|PMID:15639194)
Ensembl
RGD
PMID:15639194 GO_REF:0000107 MGI:3526480 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Apoe apolipoprotein E involved_in ISO UniProtKB:P35951 (PMID:24412220) RGD PMID:24412220 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator involved_in
acts_upstream_of_or_within
ISO (PMID:20663892)
(MGI:4849624|PMID:20663892)
RGD PMID:20663892 MGI:4849624 NCBI chr19:57,484,720...57,496,539
Ensembl chr19:57,484,634...57,496,695
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:2,069,409...2,083,370
Ensembl chr14:2,069,409...2,083,370
JBrowse link
G Ephx2 epoxide hydrolase 2 involved_in ISO
IEA
(PMID:18974052)
(MGI:3829349|PMID:18974052)
GO_REF:0000107
RGD
Ensembl
PMID:18974052 GO_REF:0000107 MGI:3829349 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5648738|PMID:26049045)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:26049045 GO_REF:0000024 GO_REF:0000107 MGI:5648738 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Gnb3 G protein subunit beta 3 involved_in ISO UniProtKB:Q61011 (PMID:29206867) RGD PMID:29206867 NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262
JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P02649 (MGI:5575733|PMID:24412220)
Ensembl
RGD
PMID:24412220 GO_REF:0000107 MGI:5575733 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lmf1 lipase maturation factor 1 acts_upstream_of_or_within ISO MGI:1856820 (MGI:55554|PMID:6857276) RGD PMID:6857276 MGI:55554 NCBI chr10:14,945,185...15,031,855
Ensembl chr10:14,945,265...15,031,942
JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Serpina12 serpin family A member 12 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5568548 (MGI:5563627|PMID:22837305)
Ensembl
RGD
PMID:22837305 GO_REF:0000107 MGI:5563627 NCBI chr 6:127,696,501...127,711,238
Ensembl chr 6:127,696,252...127,711,212
JBrowse link
G Thrb thyroid hormone receptor beta IMP RGD PMID:17878314 RGD:2315101 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Ttc39b tetratricopeptide repeat domain 39B involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:5800596|PMID:27383786)
PMID:21873635
UniProt
RGD
PMID:27383786, PMID:21873635 GO_REF:0000024 MGI:5800596, RGD:13792537 NCBI chr 5:101,304,982...101,405,689
Ensembl chr 5:101,304,982...101,405,656
JBrowse link
G Ttc39d tetratricopeptide repeat domain 39D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:2,886,764...2,895,118
Ensembl chr 6:2,886,764...2,895,118
JBrowse link
sterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07021955.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr13:100,431,390...100,450,209 JBrowse link
G AABR07060293.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 4:66,336,143...66,336,901 JBrowse link
G Ch25h cholesterol 25-hydroxylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:252,807,062...252,811,409
Ensembl chr 1:252,807,065...252,808,380
JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:51,229,697...51,236,447
Ensembl chr13:51,229,890...51,236,463
JBrowse link
G Cyb5r2 cytochrome b5 reductase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:171,971,424...171,981,586
Ensembl chr 1:171,971,701...171,979,933
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2387406 (MGI:3056828|PMID:15005800)
RGD PMID:15005800, PMID:21873635 MGI:3056828, RGD:13792537 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Ebp EBP, cholestenol delta-isomerase acts_upstream_of_or_within
involved_in
TAS
ISO
IBA
MGI:1857832 (MGI:1339492|PMID:10391218)
PMID:21873635
RGD PMID:10391218, PMID:11171067, PMID:21873635 MGI:1339492, RGD:628445, RGD:13792537 NCBI chr  X:15,049,394...15,055,782
Ensembl chr  X:15,049,462...15,055,781
JBrowse link
G Faxdc2 fatty acid hydroxylase domain containing 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:43,500,825...43,526,376
Ensembl chr10:43,502,931...43,512,287
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Insig1 insulin induced gene 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1920249 (MGI:3689278|PMID:16955138)
RGD PMID:16955138, PMID:21873635 MGI:3689278, RGD:13792537 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insig2 insulin induced gene 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1916289 (MGI:3689278|PMID:16955138)
RGD PMID:16955138, PMID:21873635 MGI:3689278, RGD:13792537 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Lbr lamin B receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:100,431,390...100,450,209 JBrowse link
G Msmo1 methylsterol monooxygenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link
G Pmvk phosphomevalonate kinase involved_in ISO (PMID:16519518) RGD PMID:16519518 NCBI chr 2:188,784,329...188,793,890
Ensembl chr 2:188,784,222...188,793,895
JBrowse link
G Sc5d sterol-C5-desaturase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050
JBrowse link
G Sqle squalene epoxidase involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:30626872)
UniProt
RGD
PMID:30626872, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:221,426,017...221,430,340
Ensembl chr 1:221,425,987...221,431,713
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      organic substance metabolic process 11337
        organic hydroxy compound metabolic process 550
          sterol metabolic process 148
            cholesterol metabolic process + 140
            ecdysone metabolic process + 0
            ergosterol metabolic process + 0
            sterol acetylation 0
            sterol biosynthetic process + 64
            sterol catabolic process + 10
            sterol deacetylation 0
            zymosterol metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      primary metabolic process 10565
        lipid metabolic process 1362
          steroid metabolic process 333
            sterol metabolic process 148
              cholesterol metabolic process + 140
              ecdysone metabolic process + 0
              ergosterol metabolic process + 0
              sterol acetylation 0
              sterol biosynthetic process + 64
              sterol catabolic process + 10
              sterol deacetylation 0
              zymosterol metabolic process + 0
paths to the root