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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic vesicle docking
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Accession:GO:0016081 term browser browse the term
Definition:The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process.
Comment:Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission (dos, pvn, fk synapse project 2015).
Synonyms:exact_synonym: synaptic vesicle docking involved in exocytosis
 related_synonym: synaptic vesicle docking during exocytosis



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synaptic vesicle docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctbp2 C-terminal binding protein 2 involved_in ISO (PMID:26929012) RGD PMID:26929012 NCBI chr 1:187,782,064...187,918,115
Ensembl chr 1:187,782,682...187,920,222
JBrowse link
G Ppfia3 PTPRF interacting protein alpha 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:29439199)
Ensembl
RGD
PMID:29439199 GO_REF:0000107 NCBI chr 1:95,817,110...95,845,950
Ensembl chr 1:95,817,110...95,845,798
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in ISO (PMID:21241895) RGD PMID:21241895 NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in ISO (PMID:21241895) RGD PMID:21241895 NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491
JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 involved_in TAS PMID:9704016 UniProt PMID:9704016 RGD:70020 NCBI chr 1:202,002,970...202,045,343
Ensembl chr 1:202,002,970...202,044,283
JBrowse link
G Stx1a syntaxin 1A involved_in IEP PMID:1321498 UniProt PMID:1321498 RGD:8553325 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
JBrowse link
G Stx1b syntaxin 1B involved_in ISS
ISO
IEA
GO_REF:0000024
UniProtKB:O35526 (MGI:5521403|PMID:24133272), (MGI:5603022|PMID:24587181)
GO_REF:0000107
ParkinsonsUK-UCL
RGD
Ensembl
PMID:24133272 PMID:24587181 GO_REF:0000024 GO_REF:0000107 MGI:5521403 MGI:5603022 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280
JBrowse link
G Stx3 syntaxin 3 TAS RGD PMID:7690687 RGD:68313 NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805
JBrowse link
G Stx4 syntaxin 4 IDA RGD PMID:7690687 RGD:68313 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979
JBrowse link
G Syde1 synapse defective Rho GTPase homolog 1 acts_upstream_of_or_within ISO MGI:4841821 (PMID:23791195) RGD PMID:23791195 NCBI chr 7:11,032,931...11,038,917
Ensembl chr 7:11,032,898...11,039,869
JBrowse link
G Tprg1l tumor protein p63 regulated 1-like involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:6385150 (PMID:33431696)
Ensembl
RGD
PMID:33431696 GO_REF:0000107 NCBI chr 5:164,722,151...164,725,358
Ensembl chr 5:164,710,285...164,725,425
JBrowse link
G Unc13a unc-13 homolog A involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1342278 (PMID:19558619)
GO_Central
RGD
PMID:19558619 GO_REF:0000033 NCBI chr16:18,333,910...18,381,813
Ensembl chr16:18,336,229...18,381,872
JBrowse link
G Unc13b unc-13 homolog B involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:3051532 (PMID:19558619)
GO_Central
RGD
PMID:19558619 GO_REF:0000033 NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926
JBrowse link
G Unc13c unc-13 homolog C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:74,247,026...74,697,629
Ensembl chr 8:74,247,899...74,673,223
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 involved_in ISO (PMID:25374362) RGD PMID:25374362 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
JBrowse link
regulation of synaptic vesicle docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in ISO (PMID:17660813) RGD PMID:17660813 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Septin5 septin 5 involved_in ISO (PMID:20624595) RGD PMID:20624595 NCBI chr11:82,373,601...82,379,393
Ensembl chr11:82,369,754...82,379,393
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19870
    cellular process 18312
      exocytic process 99
        vesicle docking involved in exocytosis 35
          synaptic vesicle docking 17
            regulation of synaptic vesicle docking 2
            synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
Path 2
Term Annotations click to browse term
  biological_process 19870
    biological regulation 13395
      regulation of biological process 12997
        signaling 7618
          cell-cell signaling 1461
            synaptic signaling 989
              trans-synaptic signaling 953
                anterograde trans-synaptic signaling 945
                  chemical synaptic transmission 945
                    neurotransmitter secretion 197
                      synaptic vesicle exocytosis 132
                        synaptic vesicle docking 17
                          regulation of synaptic vesicle docking 2
                          synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
paths to the root