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ONTOLOGY REPORT - ANNOTATIONS

Term:synaptic vesicle docking
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Accession:GO:0016081 term browser browse the term
Definition:The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process.
Comment:Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission (dos, pvn, fk synapse project 2015).
Synonyms:exact_synonym: synaptic vesicle docking involved in exocytosis
 related_synonym: synaptic vesicle docking during exocytosis


show annotations for term's descendants           Sort by:
synaptic vesicle docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctbp2 C-terminal binding protein 2 involved_in ISO
IEA 		(PMID:26929012)
GO_REF:0000107 		RGD
Ensembl		 PMID:26929012 GO_REF:0000107 NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:197,212,133...197,254,261 		JBrowse link
G Ppfia3 PTPRF interacting protein alpha 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:29439199) 		Ensembl
RGD		 PMID:29439199 GO_REF:0000107 NCBI chr 1:104,953,598...104,982,373
Ensembl chr 1:104,953,598...104,982,278 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in ISO
IBA 		(PMID:21241895)
GO_REF:0000033 		RGD
GO_Central		 PMID:21241895 GO_REF:0000033 NCBI chr 9:32,193,352...32,692,998
Ensembl chr 9:32,193,352...32,692,772 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in ISO
IBA 		(PMID:21241895)
GO_REF:0000033 		RGD
GO_Central		 PMID:21241895 GO_REF:0000033 NCBI chr 7:72,133,004...72,644,059
Ensembl chr 7:72,133,170...72,645,499 		JBrowse link
G Rims3 regulating synaptic membrane exocytosis 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:139,714,302...139,754,145
Ensembl chr 5:139,714,320...139,754,145 		JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 involved_in TAS PMID:9704016 UniProt PMID:9704016 RGD:70020 NCBI chr 1:211,432,373...211,473,016
Ensembl chr 1:211,432,373...211,473,306 		JBrowse link
G Stx1a syntaxin 1A involved_in IEP PMID:1321498 UniProt PMID:1321498 RGD:8553325 NCBI chr12:27,278,517...27,306,547
Ensembl chr12:27,278,517...27,306,471 		JBrowse link
G Stx1b syntaxin 1B involved_in ISS
ISO
IEA 		GO_REF:0000024
UniProtKB:O35526 (PMID:24133272), (PMID:24587181)
GO_REF:0000107 		ParkinsonsUK-UCL
RGD
Ensembl		 PMID:24133272 PMID:24587181 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:191,846,016...191,864,878
Ensembl chr 1:191,833,743...191,871,633 		JBrowse link
G Stx3 syntaxin 3 TAS RGD PMID:7690687 RGD:68313 NCBI chr 1:217,940,697...218,114,865
Ensembl chr 1:217,909,169...218,110,466 		JBrowse link
G Stx4 syntaxin 4 IDA RGD PMID:7690687 RGD:68313 NCBI chr 1:191,880,549...191,890,333
Ensembl chr 1:191,881,559...191,896,774 		JBrowse link
G Syde1 synapse defective Rho GTPase homolog 1 acts_upstream_of_or_within ISO MGI:4841821 (PMID:23791195) RGD PMID:23791195 NCBI chr 7:11,683,505...11,689,491
Ensembl chr 7:11,681,111...11,690,443 		JBrowse link
G Tprg1l tumor protein p63 regulated 1-like acts_upstream_of_or_within ISO
IEA 		MGI:6385150 (PMID:33431696)
GO_REF:0000107 		RGD
Ensembl		 PMID:33431696 GO_REF:0000107 NCBI chr 5:170,004,577...170,007,784
Ensembl chr 5:170,004,577...170,007,983 		JBrowse link
G Unc13a unc-13 homolog A involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:1342278 (PMID:19558619) 		GO_Central
RGD		 PMID:19558619 GO_REF:0000033 NCBI chr16:18,367,891...18,415,808
Ensembl chr16:18,367,919...18,415,899 		JBrowse link
G Unc13b unc-13 homolog B involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:3051532 (PMID:19558619) 		GO_Central
RGD		 PMID:19558619 GO_REF:0000033 NCBI chr 5:62,084,809...62,299,884
Ensembl chr 5:62,084,819...62,299,884 		JBrowse link
G Unc13c unc-13 homolog C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:83,127,650...83,553,822
Ensembl chr 8:83,128,523...83,553,822 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 involved_in ISO
IMP 		(PMID:25374362) RGD PMID:25374362 PMID:23663838 RGD:616390116 NCBI chr10:54,292,423...54,296,657
Ensembl chr10:54,292,806...54,296,654 		JBrowse link
regulation of synaptic vesicle docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in ISO (PMID:17660813) RGD PMID:17660813 NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504 		JBrowse link
G Septin5 septin 5 involved_in ISO (PMID:20624595) RGD PMID:20624595 NCBI chr11:95,877,946...95,883,738
Ensembl chr11:95,873,864...95,883,737 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20668
    cellular process 19605
      exocytic process 106
        vesicle docking involved in exocytosis 36
          synaptic vesicle docking 18
            regulation of synaptic vesicle docking 2
            synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
Path 2
Term Annotations click to browse term
  biological_process 20668
    biological regulation 13898
      regulation of biological process 13474
        signaling 7941
          cell-cell signaling 1503
            synaptic signaling 1021
              trans-synaptic signaling 977
                anterograde trans-synaptic signaling 969
                  chemical synaptic transmission 969
                    neurotransmitter secretion 205
                      synaptic vesicle exocytosis 139
                        synaptic vesicle docking 18
                          regulation of synaptic vesicle docking 2
                          synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
paths to the root