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ONTOLOGY REPORT - ANNOTATIONS

Term:synaptic vesicle docking
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Accession:GO:0016081 term browser browse the term
Definition:The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process.
Comment:Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission (dos, pvn, fk synapse project 2015).
Synonyms:exact_synonym: synaptic vesicle docking involved in exocytosis
 related_synonym: synaptic vesicle docking during exocytosis

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synaptic vesicle docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTBP2 C-terminal binding protein 2 involved_in ISO (PMID:26929012) SynGO PMID:26929012 NCBI chr 9:117,635,124...117,806,908
Ensembl chr 9:117,639,317...117,804,850 		JBrowse link
G PPFIA3 PTPRF interacting protein alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,342,791...42,372,598
Ensembl chr 6:42,350,203...42,371,720 		JBrowse link
G RIMS1 regulating synaptic membrane exocytosis 1 involved_in ISO (PMID:21241895) SynGO PMID:21241895 NCBI chr17:2,690,430...3,176,794
Ensembl chr17:2,690,418...3,176,738 		JBrowse link
G RIMS2 regulating synaptic membrane exocytosis 2 involved_in ISO (PMID:21241895) SynGO PMID:21241895 NCBI chr 8:98,354,271...99,097,457
Ensembl chr 8:98,354,131...99,097,577 		JBrowse link
G STX1A syntaxin 1A involved_in ISO PMID:1321498 UniProt PMID:1321498 RGD:8553325 NCBI chr28:9,347,495...9,367,948
Ensembl chr28:9,347,532...9,368,585 		JBrowse link
G STX1B syntaxin 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:27,683,526...27,702,032
Ensembl chr 5:27,684,082...27,694,814 		JBrowse link
G STX4 syntaxin 4 ISO RGD PMID:7690687 RGD:68313 NCBI chr 5:27,725,121...27,734,442
Ensembl chr 5:27,724,495...27,732,736 		JBrowse link
G SYDE1 synapse defective Rho GTPase activating protein 1 acts_upstream_of_or_within ISO (PMID:23791195) MGI PMID:23791195 NCBI chr 6:13,709,110...13,717,249
Ensembl chr 6:13,709,148...13,716,241 		JBrowse link
G TPRG1L tumor protein p63 regulated 1 like acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:128,057,629...128,062,545
Ensembl chr20:128,059,137...128,062,455 		JBrowse link
G UNC13A unc-13 homolog A acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:19558619) MGI
TreeGrafter		 PMID:19558619 GO_REF:0000118 NCBI chr 6:16,082,703...16,167,165
Ensembl chr 6:16,084,168...16,154,812 		JBrowse link
G UNC13B unc-13 homolog B acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:19558619) MGI
TreeGrafter		 PMID:19558619 GO_REF:0000118 NCBI chr12:45,230,661...45,461,934
Ensembl chr12:45,230,659...45,461,339 		JBrowse link
G UNC13C unc-13 homolog C involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr26:28,806,368...29,196,031 JBrowse link
G VAMP2 vesicle associated membrane protein 2 involved_in ISO (PMID:25374362) SynGO
RGD		 PMID:23663838 PMID:25374362 RGD:616390116 NCBI chr16:7,539,098...7,542,466 JBrowse link
regulation of synaptic vesicle docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2A calcium/calmodulin dependent protein kinase II alpha involved_in ISO (PMID:17660813) SynGO PMID:17660813 NCBI chr23:52,829,438...52,899,428
Ensembl chr23:52,829,350...52,899,375 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19906
    cellular process 19370
      exocytic process 94
        vesicle docking involved in exocytosis 28
          synaptic vesicle docking 14
            regulation of synaptic vesicle docking 1
            synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
Path 2
Term Annotations click to browse term
  biological_process 19906
    biological regulation 12250
      regulation of biological process 11851
        signaling 6294
          cell-cell signaling 1377
            synaptic signaling 895
              trans-synaptic signaling 860
                anterograde trans-synaptic signaling 850
                  chemical synaptic transmission 850
                    neurotransmitter secretion 190
                      synaptic vesicle exocytosis 129
                        synaptic vesicle docking 14
                          regulation of synaptic vesicle docking 1
                          synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
paths to the root