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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic vesicle docking
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Accession:GO:0016081 term browser browse the term
Definition:The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process.
Comment:Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission (dos, pvn, fk synapse project 2015).
Synonyms:exact_synonym: synaptic vesicle docking involved in exocytosis
 related_synonym: synaptic vesicle docking during exocytosis


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synaptic vesicle docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctbp2 C-terminal binding protein 2 ISO (MGI:5784793|PMID:26929012) RGD PMID:26929012 MGI:5784793 NCBI chr 1:205,001,354...205,030,565
Ensembl chr 1:205,001,396...205,040,755
JBrowse link
G Ppfia3 PTPRF interacting protein alpha 3 involved_in ISO
IEA
(MGI:6120581|PMID:29439199)
GO_REF:0000107
RGD
Ensembl
PMID:29439199 GO_REF:0000107 MGI:6120581 NCBI chr 1:101,328,547...101,357,391
Ensembl chr 1:101,327,998...101,351,879
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 ISO (MGI:4939085|PMID:21241895) RGD PMID:21241895 MGI:4939085 NCBI chr 9:28,440,408...28,973,246
Ensembl chr 9:28,442,229...28,973,246
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 ISO (MGI:4939085|PMID:21241895) RGD PMID:21241895 MGI:4939085 NCBI chr 7:78,091,998...78,594,164
Ensembl chr 7:78,092,037...78,594,138
JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 involved_in TAS PMID:9704016 UniProt PMID:9704016, PMID:9704016 RGD:70020, RGD:70020 NCBI chr 1:219,964,429...220,006,811
Ensembl chr 1:219,964,429...220,005,068
JBrowse link
G Stx1a syntaxin 1A involved_in IEP PMID:1321498 UniProt PMID:1321498, PMID:1321498 RGD:8553325, RGD:8553325 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019
JBrowse link
G Stx1b syntaxin 1B involved_in ISS
ISO
GO_REF:0000024
UniProtKB:O35526 (MGI:5521403|PMID:24133272), (MGI:5603022|PMID:24587181)
ParkinsonsUK-UCL
RGD
PMID:24133272 PMID:24587181 GO_REF:0000024 MGI:5521403 MGI:5603022 NCBI chr 1:199,251,842...199,270,465
Ensembl chr 1:199,251,844...199,270,627
JBrowse link
G Stx3 syntaxin 3 TAS RGD PMID:7690687 RGD:68313 NCBI chr 1:228,137,781...228,195,004
Ensembl chr 1:228,149,867...228,194,977
JBrowse link
G Stx4 syntaxin 4 IDA RGD PMID:7690687 RGD:68313 NCBI chr 1:199,287,384...199,295,606
Ensembl chr 1:199,287,710...199,294,979
JBrowse link
G Syde1 synapse defective Rho GTPase homolog 1 ISO MGI:4841821 (MGI:5515279|PMID:23791195) RGD PMID:23791195 MGI:5515279 NCBI chr 7:14,037,646...14,043,632
Ensembl chr 7:14,037,620...14,043,779
JBrowse link
G Unc13a unc-13 homolog A involved_in ISO
IBA
MGI:1342278 (MGI:4354715|PMID:19558619)
PMID:21873635
RGD PMID:19558619, PMID:21873635, PMID:21873635 MGI:4354715, RGD:13792537, RGD:13792537 NCBI chr16:20,056,398...20,103,951
Ensembl chr16:20,056,765...20,097,287
JBrowse link
G Unc13b unc-13 homolog B involved_in ISO
IBA
MGI:3051532 (MGI:4354715|PMID:19558619)
PMID:21873635
RGD PMID:19558619, PMID:21873635, PMID:21873635 MGI:4354715, RGD:13792537, RGD:13792537 NCBI chr 5:58,505,449...58,714,396
Ensembl chr 5:58,505,500...58,715,576
JBrowse link
G Unc13c unc-13 homolog C involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 8:80,202,736...80,656,363
Ensembl chr 8:80,203,609...80,631,926
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 ISO (MGI:5617001|PMID:25374362) RGD PMID:25374362 MGI:5617001 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
regulation of synaptic vesicle docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2a calcium/calmodulin-dependent protein kinase II alpha ISO (MGI:3763684|PMID:17660813) RGD PMID:17660813 MGI:3763684 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Septin5 septin 5 ISO (MGI:4880833|PMID:20624595) RGD PMID:20624595 MGI:4880833 NCBI chr11:86,516,377...86,522,169
Ensembl chr11:86,512,797...86,522,168
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20078
    cellular process 18896
      exocytic process 99
        vesicle docking involved in exocytosis 49
          synaptic vesicle docking 16
            regulation of synaptic vesicle docking 2
            synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
Path 2
Term Annotations click to browse term
  biological_process 20078
    localization 6501
      establishment of localization 4917
        transport 4753
          export from cell 1017
            secretion by cell 966
              signal release 621
                signal release from synapse 208
                  neurotransmitter secretion 208
                    synaptic vesicle exocytosis 155
                      synaptic vesicle docking 16
                        regulation of synaptic vesicle docking 2
                        synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
paths to the root