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ONTOLOGY REPORT - ANNOTATIONS

Term:synaptic vesicle docking
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Accession:GO:0016081 term browser browse the term
Definition:The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process.
Comment:Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission (dos, pvn, fk synapse project 2015).
Synonyms:exact_synonym: synaptic vesicle docking involved in exocytosis
 related_synonym: synaptic vesicle docking during exocytosis


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synaptic vesicle docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctbp2 C-terminal binding protein 2 involved_in ISO (MGI:5784793|PMID:26929012) RGD PMID:26929012 MGI:5784793 NCBI chr 1:187,782,064...187,918,115
Ensembl chr 1:187,782,682...187,920,222 		JBrowse link
G Ppfia3 PTPRF interacting protein alpha 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6120581|PMID:29439199)		 Ensembl
RGD		 PMID:29439199 GO_REF:0000107 MGI:6120581 NCBI chr 1:95,817,110...95,845,950
Ensembl chr 1:95,817,110...95,845,798 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in ISO (MGI:4939085|PMID:21241895) RGD PMID:21241895 MGI:4939085 NCBI chr 9:24,696,959...25,196,368
Ensembl chr 9:24,698,854...25,196,631 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in ISO (MGI:4939085|PMID:21241895) RGD PMID:21241895 MGI:4939085 NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491 		JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 involved_in TAS PMID:9704016 UniProt PMID:9704016 RGD:70020 NCBI chr 1:202,002,970...202,045,343
Ensembl chr 1:202,002,970...202,044,283 		JBrowse link
G Stx1a syntaxin 1A involved_in IEP PMID:1321498 UniProt PMID:1321498 RGD:8553325 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930 		JBrowse link
G Stx1b syntaxin 1B involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:O35526 (MGI:5521403|PMID:24133272), (MGI:5603022|PMID:24587181)		 ParkinsonsUK-UCL
RGD		 PMID:24133272 PMID:24587181 GO_REF:0000024 MGI:5521403 MGI:5603022 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280 		JBrowse link
G Stx3 syntaxin 3 TAS RGD PMID:7690687 RGD:68313 NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805 		JBrowse link
G Stx4 syntaxin 4 IDA RGD PMID:7690687 RGD:68313 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
G Syde1 synapse defective Rho GTPase homolog 1 acts_upstream_of_or_within ISO MGI:4841821 (MGI:5515279|PMID:23791195) RGD PMID:23791195 MGI:5515279 NCBI chr 7:11,032,931...11,038,917
Ensembl chr 7:11,032,898...11,039,869 		JBrowse link
G Unc13a unc-13 homolog A involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1342278 (MGI:4354715|PMID:19558619)		 RGD PMID:19558619 PMID:21873635 MGI:4354715, RGD:13792537 NCBI chr16:18,336,229...18,381,811
Ensembl chr16:18,336,229...18,381,872 		JBrowse link
G Unc13b unc-13 homolog B involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3051532 (MGI:4354715|PMID:19558619)		 RGD PMID:19558619 PMID:21873635 MGI:4354715, RGD:13792537 NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926 		JBrowse link
G Unc13c unc-13 homolog C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:74,247,026...74,697,629
Ensembl chr 8:74,247,899...74,673,223 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 involved_in ISO (MGI:5617001|PMID:25374362) RGD PMID:25374362 MGI:5617001 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
regulation of synaptic vesicle docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in ISO (MGI:3763684|PMID:17660813) RGD PMID:17660813 MGI:3763684 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Septin5 septin 5 involved_in ISO (MGI:4880833|PMID:20624595) RGD PMID:20624595 MGI:4880833 NCBI chr11:82,373,601...82,379,393
Ensembl chr11:82,369,754...82,379,393 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19541
    cellular process 18407
      exocytic process 95
        vesicle docking involved in exocytosis 45
          synaptic vesicle docking 16
            regulation of synaptic vesicle docking 2
            synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
Path 2
Term Annotations click to browse term
  biological_process 19541
    localization 6501
      establishment of localization 4895
        transport 4733
          export from cell 1021
            secretion by cell 967
              signal release 625
                signal release from synapse 206
                  neurotransmitter secretion 206
                    synaptic vesicle exocytosis 154
                      synaptic vesicle docking 16
                        regulation of synaptic vesicle docking 2
                        synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
paths to the root