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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA decay
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Accession:GO:0016078 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis.
Synonyms:exact_synonym: tRNA breakdown;   tRNA catabolic process;   tRNA catabolism;   tRNA degradation
 xref: Reactome:R-HSA-9708296 "tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"


show annotations for term's descendants           Sort by:
tRNA decay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pop1 POP1 homolog, ribonuclease P/MRP subunit involved_in ISO (PMID:8918471) RGD PMID:8918471 NCBI chr 7:65,705,348...65,733,143
Ensembl chr 7:65,705,368...65,733,141 		JBrowse link
G Slfn9 schlafen family member 9 involved_in IDA PMID:29563550 UniProt PMID:29563550 RGD:13601999 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383 		JBrowse link
TRAMP-dependent tRNA surveillance pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc10 exosome component 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:158,995,313...159,018,940
Ensembl chr 5:158,995,313...159,018,940 		JBrowse link
G Exosc2 exosome component 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575 		JBrowse link
G Exosc3 exosome component 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060 		JBrowse link
G Exosc7 exosome component 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270 		JBrowse link
G Exosc8 exosome component 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928 		JBrowse link
G Exosc9 exosome component 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051 		JBrowse link
G Zcchc7 zinc finger CCHC-type containing 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:58,992,558...59,173,308
Ensembl chr 5:58,993,290...59,173,300 		JBrowse link
tRNA destabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ang angiogenin involved_in ISO (PMID:33986151) RGD PMID:33986151 NCBI chr15:24,312,711...24,323,361 JBrowse link
tRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl1 methyltransferase 1, tRNA methylguanosine involved_in ISO (PMID:36599982), (PMID:36599985) RGD PMID:36599982 PMID:36599985 NCBI chr 7:62,864,860...62,869,202
Ensembl chr 7:62,864,853...62,869,202 		JBrowse link
G Nsun2 NOP2/Sun RNA methyltransferase 2 involved_in ISO (PMID:22885326) RGD PMID:22885326 NCBI chr 1:33,662,139...33,685,887
Ensembl chr 1:33,662,139...33,685,862 		JBrowse link
G Rnh1 ribonuclease/angiogenin inhibitor 1 involved_in ISO
IEA		 (PMID:23843625)
GO_REF:0000107		 RGD
Ensembl		 PMID:23843625 GO_REF:0000107 NCBI chr 1:196,269,293...196,281,763
Ensembl chr 1:196,269,293...196,281,910 		JBrowse link
G Slfn2 schlafen family member 2 involved_in ISO (PMID:33986151) RGD PMID:33986151 NCBI chr10:67,953,322...67,959,659
Ensembl chr10:67,953,171...67,959,458 		JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22885326)		 UniProt
RGD		 PMID:22885326 GO_REF:0000024 NCBI chr17:76,601,966...76,646,104
Ensembl chr17:76,610,543...76,645,439 		JBrowse link
tRNA surveillance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trnt1 tRNA nucleotidyl transferase 1 involved_in ISO (PMID:22076379), (PMID:25640237) RGD PMID:22076379 PMID:25640237 NCBI chr 4:139,681,115...139,703,611
Ensembl chr 4:139,680,858...139,703,611 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20537
    cellular process 19526
      metabolic process 12168
        catabolic process 2918
          macromolecule catabolic process 1678
            nucleic acid catabolic process 421
              RNA catabolic process 391
                tRNA decay 16
                  negative regulation of tRNA catabolic process + 5
                  positive regulation of tRNA catabolic process + 1
                  regulation of tRNA catabolic process + 6
                  tRNA surveillance + 8
Path 2
Term Annotations click to browse term
  biological_process 20537
    cellular process 19526
      metabolic process 12168
        primary metabolic process 10755
          nucleobase-containing compound metabolic process 5945
            nucleic acid metabolic process 5329
              nucleic acid catabolic process 421
                RNA catabolic process 391
                  tRNA decay 16
                    negative regulation of tRNA catabolic process + 5
                    positive regulation of tRNA catabolic process + 1
                    regulation of tRNA catabolic process + 6
                    tRNA surveillance + 8
paths to the root