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ONTOLOGY REPORT - ANNOTATIONS


Term:rRNA catabolic process
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Accession:GO:0016075 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes.
Synonyms:exact_synonym: rRNA breakdown;   rRNA catabolism;   rRNA degradation


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rRNA catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC118772.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:70,484,134...70,506,963 JBrowse link
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease ISO
IBA
(PMID:20368444)
PMID:21873635
RGD PMID:20368444, PMID:21873635 RGD:13792537 NCBI chr15:83,466,330...83,494,107
Ensembl chr15:83,466,428...83,494,423
JBrowse link
G Dis3l DIS3-like exosome 3'-5' exoribonuclease ISO
IBA
(PMID:20368444), (PMID:20531389)
PMID:21873635
RGD PMID:20368444, PMID:20531389, PMID:21873635 RGD:13792537 NCBI chr 8:69,771,211...69,807,880
Ensembl chr 8:69,771,197...69,807,826
JBrowse link
G Drosha drosha ribonuclease III IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:62,887,267...63,000,307
Ensembl chr 2:62,887,267...62,999,572
JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 ISO (PMID:11175748) RGD PMID:11175748 NCBI chr 1:192,126,023...192,142,865
Ensembl chr 1:192,126,023...192,142,854
JBrowse link
G Exosc4 exosome component 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:117,390,302...117,393,044
Ensembl chr 7:117,390,285...117,393,719
JBrowse link
G Exosc5 exosome component 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,452,104...82,461,607
Ensembl chr 1:82,452,469...82,461,606
JBrowse link
G Exosc6 exosome component 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:43,190,879...43,193,164
Ensembl chr19:43,191,390...43,192,208
JBrowse link
G Exosc7 exosome component 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:132,204,628...132,229,968
Ensembl chr 8:132,204,604...132,229,969
JBrowse link
G Exosc8 exosome component 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:143,925,643...143,932,240
Ensembl chr 2:143,925,546...143,931,940
JBrowse link
G Exosc9 exosome component 9 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:123,264,679...123,275,623
Ensembl chr 2:123,264,694...123,294,880
JBrowse link
G Slfn13 schlafen family member 13 IDA PMID:29563550 UniProt PMID:29563550 RGD:13601999 NCBI chr10:70,326,157...70,343,024
Ensembl chr10:70,326,157...70,342,492
JBrowse link
G Slfn14 schlafen family member 14 ISO (MGI:MGI:5705207|PMID:25996083) RGD PMID:25996083 MGI:MGI:5705207 NCBI chr10:70,493,340...70,504,810 JBrowse link
G Trir telomerase RNA component interacting RNase ISO (PMID:28322335) RGD PMID:28322335 NCBI chr19:26,142,720...26,146,136
Ensembl chr19:26,142,720...26,146,136
JBrowse link
G Xrn1 5'-3' exoribonuclease 1 ISO
IBA
(PMID:20368444)
PMID:21873635
RGD PMID:20368444, PMID:21873635 RGD:13792537 NCBI chr 8:103,774,125...103,883,563
Ensembl chr 8:103,774,358...103,878,899
JBrowse link
nonfunctional rRNA decay term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pelo pelota mRNA surveillance and ribosome rescue factor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:47,266,758...47,268,526
Ensembl chr 2:47,266,738...47,268,625
JBrowse link
nuclear polyadenylation-dependent rRNA catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc10 exosome component 10 ISO
IBA
(PMID:16455498)
PMID:21873635
RGD PMID:16455498, PMID:21873635 RGD:13792537 NCBI chr 5:165,374,964...165,398,195
Ensembl chr 5:165,374,951...165,398,217
JBrowse link
G Exosc2 exosome component 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:10,151,734...10,161,997
Ensembl chr 3:10,151,284...10,161,989
JBrowse link
G Exosc3 exosome component 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:60,866,498...60,871,734
Ensembl chr 5:60,868,502...60,871,705
JBrowse link
G Exosc7 exosome component 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:132,204,628...132,229,968
Ensembl chr 8:132,204,604...132,229,969
JBrowse link
G Exosc8 exosome component 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:143,925,643...143,932,240
Ensembl chr 2:143,925,546...143,931,940
JBrowse link
G Exosc9 exosome component 9 ISO
IBA
(PMID:16455498)
PMID:21873635
RGD PMID:16455498, PMID:21873635 RGD:13792537 NCBI chr 2:123,264,679...123,275,623
Ensembl chr 2:123,264,694...123,294,880
JBrowse link
regulation of rRNA stability term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx49 DEAD-box helicase 49 ISO (PMID:29618122) RGD PMID:29618122 NCBI chr16:20,873,585...20,881,312
Ensembl chr16:20,873,642...20,881,439
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      primary metabolic process 10904
        nucleobase-containing compound metabolic process 5483
          nucleobase-containing compound catabolic process 373
            RNA catabolic process 266
              ncRNA catabolic process 37
                rRNA catabolic process 20
                  cytoplasmic polyadenylation-dependent rRNA catabolic process 0
                  nonfunctional rRNA decay 1
                  nuclear polyadenylation-dependent rRNA catabolic process + 6
                  regulation of rRNA catabolic process + 1
Path 2
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      cellular metabolic process 11067
        cellular aromatic compound metabolic process 5709
          nucleobase-containing compound metabolic process 5483
            nucleic acid metabolic process 4980
              RNA metabolic process 4470
                ncRNA metabolic process 523
                  rRNA metabolic process 273
                    rRNA catabolic process 20
                      cytoplasmic polyadenylation-dependent rRNA catabolic process 0
                      nonfunctional rRNA decay 1
                      nuclear polyadenylation-dependent rRNA catabolic process + 6
                      regulation of rRNA catabolic process + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.