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ONTOLOGY REPORT - ANNOTATIONS


Term:coenzyme A biosynthetic process
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Accession:GO:0015937 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
Synonyms:exact_synonym: CoA biosynthesis;   coenzyme A anabolism;   coenzyme A biosynthesis;   coenzyme A formation;   coenzyme A synthesis
 alt_id: GO:0006764
 xref: Reactome:R-HSA-196783 "Coenzyme A biosynthesis"



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coenzyme A biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) RGD PMID:17371050 NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Acot7 acyl-CoA thioesterase 7 involved_in ISO
IEA
(PMID:10578051)
GO_REF:0000107
RGD
Ensembl
PMID:10578051 GO_REF:0000107 NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309
JBrowse link
G Ak6 adenylate kinase 6 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:31,794,316...31,806,375
Ensembl chr 2:31,794,519...31,806,371
Ensembl chr20:31,794,519...31,806,371
JBrowse link
G Coasy Coenzyme A synthase involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:11923312)
GO_REF:0000033
(PMID:11980892)
RGD
GO_Central
PMID:11923312 PMID:11980892 GO_REF:0000033 NCBI chr10:86,014,566...86,018,849
Ensembl chr10:86,014,597...86,018,841
JBrowse link
G Dcakd dephospho-CoA kinase domain containing involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:88,457,829...88,489,011
Ensembl chr10:87,957,740...87,980,054
JBrowse link
G Pank1 pantothenate kinase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:2176050|MGI:4462018 (PMID:20559429), (PMID:22815849)
MGI:1921700 (PMID:10625688), (PMID:22815849)
GO_Central
RGD
PMID:10625688 PMID:20559429 PMID:22815849 GO_REF:0000033 NCBI chr 1:241,737,371...241,808,126
Ensembl chr 1:232,328,430...232,396,829
JBrowse link
G Pank2 pantothenate kinase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1922985|MGI:3514020 (PMID:22815849), (PMID:24316510)
MGI:2176050|MGI:5446719 (PMID:22815849)
GO_Central
RGD
PMID:22815849 PMID:24316510 GO_REF:0000033 NCBI chr 3:118,483,382...118,519,551
Ensembl chr 3:118,483,444...118,518,320
JBrowse link
G Pank3 pantothenate kinase 3 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:20797618), (PMID:30927326)
GO_REF:0000033
(PMID:16040613)
RGD
GO_Central
PMID:16040613 PMID:20797618 PMID:30927326 GO_REF:0000033 NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955
JBrowse link
G Pank4 pantothenate kinase 4 involved_in IEA
IBA
GO_REF:0000104
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000104 NCBI chr 5:165,525,340...165,542,139
Ensembl chr 5:165,525,402...165,542,135
JBrowse link
G Ppcdc phosphopantothenoylcysteine decarboxylase involved_in ISO
IBA
(PMID:11923312)
GO_REF:0000033
RGD
GO_Central
PMID:11923312 GO_REF:0000033 NCBI chr 8:57,815,195...57,842,863
Ensembl chr 8:57,815,195...58,000,570
JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase involved_in ISO
IBA
(PMID:11923312), (PMID:29754768)
GO_REF:0000033
RGD
GO_Central
PMID:11923312 PMID:29754768 GO_REF:0000033 NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933
JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      metabolic process 12171
        purine-containing compound metabolic process 619
          purine-containing compound biosynthetic process 235
            coenzyme A biosynthetic process 12
              regulation of coenzyme A biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      metabolic process 12171
        primary metabolic process 10746
          nucleobase-containing compound metabolic process 5951
            nucleobase-containing small molecule metabolic process 731
              nucleoside phosphate metabolic process 696
                coenzyme A metabolic process 19
                  coenzyme A biosynthetic process 12
                    regulation of coenzyme A biosynthetic process 0
paths to the root