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ONTOLOGY REPORT - ANNOTATIONS


Term:coenzyme A biosynthetic process
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Accession:GO:0015937 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
Synonyms:exact_synonym: CoA biosynthesis;   coenzyme A anabolism;   coenzyme A biosynthesis;   coenzyme A formation;   coenzyme A synthesis
 alt_id: GO:0006764
 xref: MetaCyc:COA-PWY;   MetaCyc:PANTOSYN-PWY;   MetaCyc:PWY-4221



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coenzyme A biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IDA (PMID:17371050) BHF-UCL PMID:17371050 NCBI chr11:108,116,705...108,148,822
Ensembl chr11:108,116,695...108,147,603
JBrowse link
G ACOT7 acyl-CoA thioesterase 7 involved_in IDA (PMID:10578051) BHF-UCL PMID:10578051 NCBI chr 1:6,264,272...6,393,767
Ensembl chr 1:6,264,269...6,393,767
JBrowse link
G COASY Coenzyme A synthase involved_in
acts_upstream_of_or_within
IEA
ISO
TAS
IDA
IBA
(MGI:2181228|PMID:11980892)
(PMID:11994049)
(PMID:11923312)
(PMID:21873635)
UniProt
MGI
Reactome
InterPro
GO_Central
PMID:11923312 PMID:11980892 PMID:11994049 PMID:21873635 GO_REF:0000002 GO_REF:0000041 MGI:2181228 Reactome:R-HSA-196783 NCBI chr17:42,562,148...42,566,277
Ensembl chr17:42,561,467...42,566,277
JBrowse link
G DCAKD dephospho-CoA kinase domain containing involved_in IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr17:45,023,338...45,061,131
Ensembl chr17:45,023,340...45,061,109
JBrowse link
G PANK1 pantothenate kinase 1 involved_in
acts_upstream_of_or_within
TAS
ISO
IBA
IEA
(MGI:3607004|PMID:16040613)
(MGI:4461354|PMID:20559429), (MGI:5446555|PMID:22815849)
(PMID:21873635)
Reactome
MGI
GO_Central
UniProt
PMID:16040613 PMID:20559429 PMID:21873635 PMID:22815849 GO_REF:0000041 MGI:3607004 MGI:4461354 MGI:5446555 Reactome:R-HSA-196783 NCBI chr10:89,579,495...89,645,242
Ensembl chr10:89,582,988...89,645,418
JBrowse link
G PANK2 pantothenate kinase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
NAS
TAS
(PMID:21873635)
(MGI:5446555|PMID:22815849)
(PMID:22221393)
GO_Central
MGI
UniProt
ParkinsonsUK-UCL
Reactome
InterPro
PMID:21873635 PMID:22221393 PMID:22815849 GO_REF:0000002 GO_REF:0000041 MGI:5446555 Reactome:R-HSA-196783 NCBI chr20:3,888,781...3,929,887
Ensembl chr20:3,888,839...3,929,887
JBrowse link
G PANK3 pantothenate kinase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
IDA
IMP
IEA
(PMID:21873635)
(MGI:3607004|PMID:16040613)
(PMID:30927326)
(PMID:20797618)
GO_Central
MGI
UniProt
InterPro
PMID:16040613 PMID:20797618 PMID:21873635 PMID:30927326 GO_REF:0000002 GO_REF:0000041 MGI:3607004 NCBI chr 5:168,548,495...168,579,368
Ensembl chr 5:168,548,495...168,579,368
JBrowse link
G PANK4 pantothenate kinase 4 (inactive) involved_in IEA
IBA
(PMID:21873635) UniProt
InterPro
GO_Central
PMID:21873635 GO_REF:0000002 GO_REF:0000104 NCBI chr 1:2,508,537...2,526,622
Ensembl chr 1:2,508,537...2,526,597
JBrowse link
G PPCDC phosphopantothenoylcysteine decarboxylase involved_in IEA
IBA
IDA
(PMID:21873635)
(PMID:11923312)
UniProt
GO_Central
PMID:11923312 PMID:21873635 GO_REF:0000041 NCBI chr15:75,023,544...75,060,180
Ensembl chr15:75,023,586...75,117,462
JBrowse link
G PPCS phosphopantothenoylcysteine synthetase involved_in IEA
IBA
IMP
IDA
(PMID:21873635)
(PMID:29754768)
(PMID:11923312)
UniProt
GO_Central
PMID:11923312 PMID:21873635 PMID:29754768 GO_REF:0000041 NCBI chr 1:42,456,341...42,473,417
Ensembl chr 1:42,456,117...42,473,385
JBrowse link
G SLC25A16 solute carrier family 25 member 16 involved_in TAS Reactome Reactome:R-HSA-196783 NCBI chr10:68,477,998...68,527,523
Ensembl chr10:68,477,998...68,527,523
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18539
    metabolic process 11872
      cellular metabolic process 10812
        cellular aromatic compound metabolic process 6018
          purine-containing compound metabolic process 457
            purine nucleoside bisphosphate metabolic process 134
              coenzyme A metabolic process 18
                coenzyme A biosynthetic process 11
                  regulation of coenzyme A biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 18539
    metabolic process 11872
      cellular metabolic process 10812
        cellular aromatic compound metabolic process 6018
          nucleobase-containing compound metabolic process 5775
            nucleobase-containing small molecule metabolic process 616
              nucleoside phosphate metabolic process 537
                nucleotide metabolic process 528
                  purine nucleotide metabolic process 431
                    purine ribonucleotide metabolic process 401
                      coenzyme A metabolic process 18
                        coenzyme A biosynthetic process 11
                          regulation of coenzyme A biosynthetic process 0
paths to the root